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1. 发明授权

US5723595A Plant desaturases--compositions and uses 失效
标题翻译：植物去饱和酶 - 组合物和用途
公开(公告)号：US5723595A
公开(公告)日：1998-03-03
申请号：US471791
申请日：1995-06-06
申请人： Gregory A. Thompson , Vic C. Knauf
发明人： Gregory A. Thompson , Vic C. Knauf
IPC分类号： A23D9/00 , C12N9/02 , C12N15/82 , C12P7/64 , C12N15/29 , C07H21/04 , C12N15/63
CPC分类号： C12N9/0083 , A23D9/00 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12Y114/19002
摘要： By this invention, compositions and methods of use of plant desaturase enzymes, especially .DELTA.-9 desaturases, are provided. Of special interest are methods and compositions of amino acids and nucleic acid sequences related to biologically active plant desaturases as well as sequences, especially nucleic acid sequences, which are to be used as probes, vectors for transformation or cloning intermediates. Biologically active sequences may be found in a sense or anti-sense orientation as to transcriptional regulatory regions found in various constructs.
摘要翻译：通过本发明，提供了植物去饱和酶，特别是DELTA -9去饱和酶的组合物和使用方法。特别感兴趣的是与生物活性植物去饱和酶相关的氨基酸和核酸序列的方法和组合物以及用作探针的序列，特别是核酸序列，用于转化或克隆中间体的载体。关于在各种构建体中发现的转录调控区域，可以在有义或反义方向上发现生物活性序列。

2. 发明授权

US5475099A Plant fatty acid synthases 失效
标题翻译：植物脂肪酸合成酶
公开(公告)号：US5475099A
公开(公告)日：1995-12-12
申请号：US721761
申请日：1991-06-26
申请人： Vic C. Knauf , Gregory A. Thompson
发明人： Vic C. Knauf , Gregory A. Thompson
IPC分类号： A01H5/00 , C07K1/14 , C07K14/415 , C11B1/00 , C12N5/10 , C12N9/02 , C12N9/10 , C12N15/09 , C12N15/29 , C12N15/52 , C12N15/82 , C12P7/64 , C07H21/04
CPC分类号： C12N9/0083 , C12N15/52 , C12N15/8247 , C12N9/1029 , C12P7/6463 , C12Y114/19002
摘要： By this invention, compositions and methods of use related to .beta.-ketoacyl-ACP synthase, hereinafter also referred to as "synthase", are provided. Also of interest are methods and compositions of amino acid and nucleic acid sequences related to biologically active plant synthase(s).In particular, synthase protein preparations which have relatively high turnover (specific activity) are of interest for use in a variety of applications, in vitro and in vivo. Especially, protein preparations having synthase I and/or synthase II activities are contemplated hereunder. Synthase activities are distinguished by the preferential activity towards longer and shorter acyl-ACPs. Protein preparations having preferential activity towards shorter chain length acyl-ACPs are synthase I-type. Synthases having preferential activity towards longer chain length acyl-ACPs are synthase II-type. Of special interest are synthases obtainable from Ricinus communis.
摘要翻译：通过本发明，提供了与β-酮酰基-ACP合酶相关的组合物和使用方法，以下也称为“合酶”。还感兴趣的是与生物活性植物合酶相关的氨基酸和核酸序列的方法和组合物。特别地，具有相对高的周转率（比活性）的合成酶蛋白制剂在体外和体内用于各种应用中是有意义的。特别地，考虑到具有合酶I和/或合酶II活性的蛋白质制剂。合酶活性的区别在于对较长和较短酰基-ACP的优先活性。对较短链长酰基-ACP具有优先活性的蛋白质制剂是合酶I型。对较长链长酰基-ACP具有优先活性的合成酶是合酶II型。特别感兴趣的是从蓖麻（Ricinus communis）获得的合成酶。

3. 发明授权

US07572926B2 Plant desaturases—compositions and uses 失效
标题翻译：植物去饱和酶 - 组合物和用途
公开(公告)号：US07572926B2
公开(公告)日：2009-08-11
申请号：US11415867
申请日：2006-05-02
申请人： Gregory A. Thompson , Vic C. Knauf
发明人： Gregory A. Thompson , Vic C. Knauf
IPC分类号： C11B1/00 , C12N15/82
CPC分类号： C12N9/0083 , A23D9/00 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12Y114/19002
摘要： By this invention, compositions and methods of use of plant desaturase enzymes, especially Δ-9 desaturases, are provided. Of special interest are methods and compositions of amino acids and nucleic acid sequences related to biologically active plant desaturases as well as sequences, especially nucleic acid sequences, which are to be used as probes, vectors for transformation or cloning intermediates. Biologically active sequences may be found in a sense or anti-sense orientation as to transcriptional regulatory regions found in various constructs.
摘要翻译：通过本发明，提供了植物去饱和酶，特别是Δ-9去饱和酶的组合物和方法。特别感兴趣的是与生物活性植物去饱和酶相关的氨基酸和核酸序列的方法和组合物以及用作探针的序列，特别是核酸序列，用于转化或克隆中间体的载体。关于在各种构建体中发现的转录调控区域，可以在有义或反义方向上发现生物活性序列。

4. 发明授权

US07498455B2 Plant oils with altered oleic acid content 失效
标题翻译：具有油酸含量变化的植物油
公开(公告)号：US07498455B2
公开(公告)日：2009-03-03
申请号：US10259604
申请日：2002-09-30
申请人： Katayoon Dehesh , Vic C. Knauf , Gregory A. Thompson
发明人： Katayoon Dehesh , Vic C. Knauf , Gregory A. Thompson
IPC分类号： C07C53/00 , C07C57/00
CPC分类号： C12N9/1029 , C12N9/0083 , C12N15/52 , C12N15/8247 , C12P7/6409 , C12P7/6463 , C12Y114/19002
摘要： By this invention, methods to produce oleic fatty acids in plant seed oils are provided. The methods of the present invention generally involve the suppression of a host plant cells endogenous β-ketoacyl-ACP synthase I protein. Also described in the instant invention are the plants, cells and oils obtained therefrom.
摘要翻译：通过本发明，提供了在植物种子油中制备油酸脂肪酸的方法。本发明的方法通常涉及抑制宿主植物细胞内源性β-酮酸酰-ACP合酶I蛋白。在本发明中也描述了由其获得的植物，细胞和油。

5. 发明授权

US06117677A Plant stearoyl-ACP desaturases genes 失效
标题翻译：植物硬脂酰ACP去饱和酶基因
公开(公告)号：US06117677A
公开(公告)日：2000-09-12
申请号：US979461
申请日：1992-11-20
申请人： Gregory A. Thompson , Vic C. Knauf
发明人： Gregory A. Thompson , Vic C. Knauf
IPC分类号： A23D9/00 , C12N9/02 , C12N15/82 , C12P7/64 , C12Q1/68 , C12N15/00 , C12N15/52
CPC分类号： C12N9/0083 , A23D9/00 , C12N15/8247 , C12P7/6463 , C12Y114/19002
摘要： The present invention relates to DNA constructs comprising a plant stearoyl-ACP desaturase and a second DNA sequence which is not naturally joined to the given plant stearoyl-ACP desaturase. The plant stearoyl-ACP desaturase is under the regulatory control of a transcription and translation initiation region preferentially expressed in plant embryo tissue.The amino acid sequence and methods to purify safflower stearoyl-ACP desaturase to homogenity are also provided.
摘要翻译：本发明涉及包含植物硬脂酰-ACP去饱和酶的DNA构建体和不是天然连接到给定植物硬脂酰-ACP去饱和酶的第二DNA序列。植物硬脂酰ACP去饱和酶处于优先在植物胚胎组织中表达的转录和翻译起始区的调控下。还提供了将红花硬脂酰-ACP去饱和酶纯化成均匀性的氨基酸序列和方法。

6. 发明授权

US5510255A Plant fatty acid synthases 失效
标题翻译：植物脂肪酸合成酶
公开(公告)号：US5510255A
公开(公告)日：1996-04-23
申请号：US978687
申请日：1993-02-01
申请人： Vic C. Knauf , Gregory A. Thompson
发明人： Vic C. Knauf , Gregory A. Thompson
IPC分类号： A01H5/00 , C07K1/14 , C07K14/415 , C11B1/00 , C12N5/10 , C12N9/02 , C12N9/10 , C12N15/09 , C12N15/29 , C12N15/52 , C12N15/82 , C12P7/64 , C12N15/10
CPC分类号： C12N9/0083 , C12N15/52 , C12N15/8247 , C12N9/1029 , C12P7/6463 , C12Y114/19002
摘要： By this invention, compositions and methods of use related to .beta.-ketoacyl-ACP synthase, hereinafter also referred to as "synthase", are provided. Also of interest are methods and compositions of amino acid and nucleic acid sequences related to biologically active plant synthase(s).In particular, synthase protein preparations which have relatively high turnover (specific activity) are of interest for use in a variety of applications, in vitro and in vivo. Especially, protein preparations having synthase I and/or synthase II activities are contemplated hereunder. Synthase activities are distinguished by the preferential activity towards longer and shorter acyl-ACPs. Protein preparations having preferential activity towards shorter chain length acyl-ACPs are synthase I-type. Synthases having preferential activity towards longer chain length acyl-ACPs are synthase II-type. Of special interest are synthases obtainable from Ricinus communis.
摘要翻译： PCT No.PCT / US91 / 05801 Sec。 371日期：1993年2月1日 102（e）1993年2月1日授权PCT 1991年8月15日提交PCT。通过本发明，提供了与β-酮酰基-ACP合酶相关的组合物和方法，以下也称为“合酶”。还感兴趣的是与生物活性植物合酶相关的氨基酸和核酸序列的方法和组合物。特别地，具有相对高的周转率（比活性）的合成酶蛋白制剂在体外和体内用于各种应用中是有意义的。特别地，考虑到具有合酶I和/或合酶II活性的蛋白质制剂。合酶活性的区别在于对较长和较短酰基-ACP的优先活性。对较短链长酰基-ACP具有优先活性的蛋白质制剂是合酶I型。对较长链长酰基-ACP具有优先活性的合成酶是合酶II型。特别感兴趣的是从蓖麻（Ricinus communis）获得的合成酶。

7. 发明授权

US07037692B1 Plant desaturases compositions and uses 失效
标题翻译：植物去饱和组合物和用途
公开(公告)号：US07037692B1
公开(公告)日：2006-05-02
申请号：US07762762
申请日：1991-09-16
申请人： Gregory A. Thompson , Vic C. Knauf
发明人： Gregory A. Thompson , Vic C. Knauf
IPC分类号： C12N9/00 , C12N15/82 , C07H21/04 , C12P7/62 , A01H1/00
CPC分类号： C12N9/0083 , A23D9/00 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6463 , C12P7/6472 , C12Y114/19002
摘要： By this invention, compositions and methods of use of plant desaturase enzymes, especially Δ-9 desaturases, are provided. Of special interest are methods and compositions of amino acids and nucleic acid sequences related to biologically active plant desaturases as well as sequences, especially nucleic acid sequences, which are to be used as probes, vectors for transformation or cloning intermediates. Biologically active sequences may be found in a sense or anti-sense orientation as to transcriptional regulatory regions found in various constructs.
摘要翻译：通过本发明，提供了植物去饱和酶，特别是Δ-9去饱和酶的组合物和方法。特别感兴趣的是与生物活性植物去饱和酶相关的氨基酸和核酸序列的方法和组合物以及用作探针的序列，特别是核酸序列，用于转化或克隆中间体的载体。关于在各种构建体中发现的转录调控区域，可以在有义或反义方向上发现生物活性序列。

8. 发明授权

US06483008B1 Methods for producing plants with elevated oleic acid content 失效
标题翻译：用于生产具有较高油酸含量的植物的方法
公开(公告)号：US06483008B1
公开(公告)日：2002-11-19
申请号：US09304603
申请日：1999-05-03
申请人： Katayoon Dehesh , Vic C. Knauf , Gregory A. Thompson
发明人： Katayoon Dehesh , Vic C. Knauf , Gregory A. Thompson
IPC分类号： A01H500
CPC分类号： C12N9/1029 , C12N9/0083 , C12N15/52 , C12N15/8247 , C12P7/6409 , C12P7/6463 , C12Y114/19002
摘要： By this invention, methods to produce oleic fatty acids in plant seed oils are provided. The methods of the present invention generally involve the suppression of a host plant cells endogenous &bgr;-ketoacyl-ACP synthase I protein. Also described in the instant invention are the plants, cells and oils obtained therefrom.
摘要翻译：通过本发明，提供了在植物种子油中制备油酸脂肪酸的方法。本发明的方法通常涉及抑制宿主植物细胞内源性β-酮酸酰-ACP合酶I蛋白。在本发明中也描述了由其获得的植物，细胞和油。

9. 发明授权

US06426447B1 Plant seed oils 失效
标题翻译：植物种子油
公开(公告)号：US06426447B1
公开(公告)日：2002-07-30
申请号：US08926522
申请日：1997-09-09
申请人： Vic C. Knauf , Gregory A. Thompson
发明人： Vic C. Knauf , Gregory A. Thompson
IPC分类号： A01H500
CPC分类号： C12N9/0083 , C12N15/8247
摘要： By this invention, modification of the fatty acid composition of a plant seed may be achieved as a result of the activity of a DNA sequence foreign to the plant species to be modified. In particular, it has been found that a plant oil having a modified fatty acid composition can be obtained upon the expression of genes derived from plants of different species than the host plant, upon the expression of genes derived from bacteria, and from the transcription of anti-sense sequences which are complementary to endogenous genes of the plant host cell. In a preferred embodiment, transcription of the fatty acid modifying foreign DNA sequence is restricted to the developing seed tissues.
摘要翻译：通过本发明，植物种子的脂肪酸组成的改变可以通过对待修饰的植物物种外来的DNA序列的活性来实现。特别地，已经发现，当从源自植物的不同种类的植物表达的基因表达时，可以获得具有改性脂肪酸组成的植物油，从表达来自细菌的基因，与植物宿主细胞的内源基因互补的反义序列。在优选的实施方案中，脂肪酸修饰外源DNA序列的转录限于显影种子组织。

10. 发明授权

US06348642B1 Ricinus communis &bgr;-ketoacyl-ACP synthase nucleic acids 失效
标题翻译：蓖麻β-酮酸酰-ACP合酶核酸
公开(公告)号：US06348642B1
公开(公告)日：2002-02-19
申请号：US07987256
申请日：1992-12-07
申请人： Vic C. Knauf , Gregory A. Thompson
发明人： Vic C. Knauf , Gregory A. Thompson
IPC分类号： A01N500
CPC分类号： C12N9/0083 , C12N9/1029 , C12N15/52 , C12N15/8247 , C12P7/6463 , C12Y114/19002
摘要： By this invention, compositions and methods of use of Ricinus communis cDNAs encoding &bgr;-ketoacyl-ACP synthase, are provided. Also of interest are plants, plant parts and plant cells comprising the nucleic acid sequences.
摘要翻译：通过本发明，提供了编码β-酮酸酰-ACP合酶的蓖麻cDNA的组合物和方法。还感兴趣的是包含核酸序列的植物，植物部分和植物细胞。

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