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1. 发明授权

US6146668A Preparation of isoflavones from legumes 失效
标题翻译：从豆类制备异黄酮
公开(公告)号：US6146668A
公开(公告)日：2000-11-14
申请号：US847850
申请日：1997-04-28
申请人： Graham E. Kelly , Jiu Li Huang , Mark G. Deacon-Shaw , Mark A. Waring
发明人： Graham E. Kelly , Jiu Li Huang , Mark G. Deacon-Shaw , Mark A. Waring
IPC分类号： C12P17/06 , C12P17/18 , C21P21/06 , A61K31/337 , A61K35/78 , C12N9/24
CPC分类号： C12P17/182 , C12P17/06
摘要： Processes for the production of isoflavones are described wherein plant material from plants of the genus leguminosae are contacted with water, an enzyme which cleaves isoflavone glycosides to the aglucone form and a C.sub.2 -C.sub.10 organic solvent, so as to form a combination, incubating the combination for a time sufficient to allow isoflavones of the aglucone form to partition into the organic solvent component, and thereafter recovering isoflavones from the organic solvent component.
摘要翻译：描述了用于生产异黄酮的方法，其中来自豆科植物的植物材料与水接触，将异黄酮糖苷切割成配基形式的酶和C2-C10有机溶剂，以形成组合，孵育组合足以允许配基形式的异黄酮分配到有机溶剂组分中，然后从有机溶剂组分中回收异黄酮。

2. 发明授权

US07033621B1 Isoflavone compositions produced from legumes 失效
标题翻译：由豆类生产的异黄酮组合物
公开(公告)号：US07033621B1
公开(公告)日：2006-04-25
申请号：US09546565
申请日：2000-04-11
申请人： Graham E. Kelly , Jiu Li Huang , Mark G. Deacon-Shaw , Mark A. Waring
发明人： Graham E. Kelly , Jiu Li Huang , Mark G. Deacon-Shaw , Mark A. Waring
IPC分类号： A01N65/00 , A61K35/78
CPC分类号： C12P17/182 , C12P17/06
摘要： Processes for the production of isoflavones are described wherein plant material from plants of the genus leguminosae are contacted with water, an enzyme which cleaves isoflavone glycosides to the aglucone form and a C2-C10 organic solvent, so as to form a combination, incubating the combination for a time sufficient to allow isoflavones of the aglucone form to partition into the organic solvent component, and thereafter recovering isoflavones from the organic solvent component.
摘要翻译：描述了用于生产异黄酮的方法，其中来自豆科植物的植物材料与水接触，将异黄酮糖苷切割成配基形式的酶和C 2 -C 10 - / SUB>有机溶剂，以形成组合，将组合温育足以使配基形式的异黄酮分配到有机溶剂组分中，然后从有机溶剂组分中回收异黄酮。

3. 发明申请

US20110312906A1 TREATMENT OR REDUCTION OF MENOPAUSAL SYMPTOMS 审中-公开
标题翻译：治疗或减少男性症状
公开(公告)号：US20110312906A1
公开(公告)日：2011-12-22
申请号：US13167439
申请日：2011-06-23
申请人： Graham E. Kelly
发明人： Graham E. Kelly
IPC分类号： A61K31/7048 , A61P5/24 , A61K31/352
CPC分类号： A61K31/353 , A61K31/35 , A61K31/352 , Y10S514/899 , A61K2300/00
摘要： There is described a method for the treatment or prevention of menopausal symptoms or osteoporosis wherein there is administered to a subject in need of such treatment a therapeutically effective amount of the isotlavone formononetin, or a method for the treatment or prevention of menopausal symptoms wherein there is administered to a subject in need of such treatment a therapeutically effective amount of the isoflavone daidzein, the isotlavone being optionally administered with one or more pharmaceutically acceptable adjuvants, carriers and/or excipients. Therapeutic uses and compositions/foods are also described, comprising daidzein or formononetin optionally in association with one or more pharmaceutically acceptable adjuvants, carriers, food components and/or excipients.
摘要翻译：描述了一种治疗或预防绝经症状或骨质疏松症的方法，其中向需要这种治疗的受试者施用治疗有效量的异黄酮黄酮生物素，或用于治疗或预防绝经症状的方法，其中存在向需要这种治疗的受试者施用治疗有效量的异黄酮黄豆苷原，所述异黄酮任选地与一种或多种药学上可接受的佐剂，载体和/或赋形剂一起施用。还描述了治疗用途和组合物/食物，其包含任选地与一种或多种药学上可接受的佐剂，载体，食物组分和/或赋形剂结合的黄豆苷原或海参素。

4. 发明授权

US06340703B1 Treatment or prevention of osteoporosis 失效
标题翻译：治疗或预防骨质疏松症
公开(公告)号：US06340703B1
公开(公告)日：2002-01-22
申请号：US09077590
申请日：1998-06-02
申请人： Graham E. Kelly
发明人： Graham E. Kelly
IPC分类号： A61K31352
CPC分类号： A61K31/353 , A61K31/35 , A61K31/352 , Y10S514/899 , A61K2300/00
摘要： There is described a method for the treatment or prevention of menopausal symptoms or osteoporosis wherein there is administered to a subject in need of such treatment a therapeutically effective amount of the isoflavone formononetin, or a method for the treatment or prevention of menopausal symptoms wherein there is administered to a subject in need of such treatment a therapeutically effective amount of the isoflavone daidzein, the isoflavone being optionally administered with one or more pharmaceutically acceptable adjuvants, carriers and/or excipients. Therapeutic uses and compositions/foods are also described, comprising daidzeii or formononetin optionally in association with one or more pharmaceutically acceptable adjuvants, carriers, food components and/or excipients.
摘要翻译：描述了治疗或预防绝经症状或骨质疏松症的方法，其中向需要这种治疗的受试者施用治疗有效量的异黄酮异黄酮酮，或用于治疗或预防绝经症状的方法，其中存在向需要这种治疗的受试者施用治疗有效量的异黄酮黄豆苷原，所述异黄酮任选地与一种或多种药学上可接受的佐剂，载体和/或赋形剂一起施用。还描述了治疗用途和组合物/食物，其包含任选地与一种或多种药学上可接受的佐剂，载体，食物组分和/或赋形剂相关联的大豆黄单胞菌属（Daidzeii）或海参素（formononetin）。

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