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    • 1. 发明授权
    • Method and apparatus for termination of tachyarrhythmias
    • 用于终止快速性心律失常的方法和装置
    • US5849031A
    • 1998-12-15
    • US991838
    • 1997-12-16
    • Gonzalo MartinezDavid LipsonTimothy G. Laske
    • Gonzalo MartinezDavid LipsonTimothy G. Laske
    • A61N1/05A61N1/39
    • A61N1/3918A61N1/0563Y10S977/952
    • An implantable medical lead for use with an implantable cardioverter defibrillator, a method of manufacture and a system employing the lead and cardioverter/defibrillator in combination. The lead is provided with an elongated insulative lead body carrying a cardioversion/defibrillation electrode, which includes a first portion displaying essentially equal attenuation of positive and negative voltage pulses and a second portion displaying differential attenuation of positive and negative voltage pulses. The cardioveter/defibrillator provides a biphasic pulse in which a higher amplitude phase of the pulse is differentially attenuated by the electrode. The electrode is fabricated in whole or in part of a valve metal such as tantalum, anodized and annealed to provide a thick, durable oxide coating.
    • 一种用于植入式心律转复除颤器的可植入医用引线,一种制造方法,以及组合使用引线和心律转复除颤器的系统。 引线设置有承载心电复律/除颤电极的细长绝缘引线体,其包括显示正负电压脉冲基本上相等的衰减的第一部分和显示正和负电压脉冲的差分衰减的第二部分。 心脏除颤器/除颤器提供双相脉冲,其中脉冲的较高振幅相位被电极差分衰减。 电极全部或部分地由诸如钽的阀金属制成,经过阳极氧化和退火,以提供厚实耐用的氧化物涂层。
    • 4. 发明授权
    • Leads for selective sensing and virtual electrodes
    • 引领选择性感应和虚拟电极
    • US09468754B2
    • 2016-10-18
    • US12474645
    • 2009-05-29
    • Gonzalo MartinezTimothy G. LaskeMark T. Marshall
    • Gonzalo MartinezTimothy G. LaskeMark T. Marshall
    • A61N1/05
    • A61N1/0563A61B5/042A61N1/0534A61N1/0541A61N1/056
    • Selective sensing implantable medical leads include pulsing and sensing portions and pulsing and not sensing portion. Leads and electrodes may be used in defibrillation and as integrated bipolar defibrillation electrodes. An entire electrode can pass charge while a valve metal or valve metal oxide portion of the electrode prevents the entire electrode from sensing, effectively rejecting unwanted signals. Differential conduction pathways, due to the valve metal and/or oxides thereof, cause the portions of the electrodes to conduct differently when used anodically and cathodically. Complex intracardiac electrical gradient can be formed along with a number of virtual electrodes within the tissue. Reentrant loops can thereby be pinned following defibrillation shock.
    • 选择性感测可植入医疗引线包括脉冲和感测部分以及脉冲和不感测部分。 引线和电极可用于除颤和作为集成的双极除颤电极。 整个电极可以通过电荷,同时电极的阀金属或阀金属氧化物部分防止整个电极感测,有效地排除不需要的信号。 由于阀门金属和/或其氧化物导致的差动传导路径导致当阳极和阴极使用时,电极的部分不同地传导。 可以与组织内的多个虚拟电极一起形成复杂的心内电梯度。 因此,除颤休克后可以固定可重入环。