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1. 发明授权

US08676297B2 Method and device for separate three-dimensional presentation of arteries and veins in a part of body 有权
标题翻译：用于在身体的一部分中单独的立体呈现动脉和静脉的方法和装置
公开(公告)号：US08676297B2
公开(公告)日：2014-03-18
申请号：US11724657
申请日：2007-03-15
申请人： Goetz Benndorf , Klaus Klingenbeck-Regn , Michael Zellerhoff
发明人： Goetz Benndorf , Klaus Klingenbeck-Regn , Michael Zellerhoff
IPC分类号： A61B5/05
CPC分类号： A61B6/481 , A61B6/504
摘要： The invention is directed to a method and a device for separate three-dimensional presentation of arteries and/or veins of a vessel system in a part of the body of a vertebrate by a rotation computer tomography. A masking run of the tomograph is undertaken without contrast media around the part of the body. Then two filling runs with contrast media are executed, with the venous phase of vessel contrasting during the first filling run occurring during the arterial phase of vessel contrasting of the second filling run and vice-versa. The data from the first and second filling run is combined into data sets from the arterial or the venous phases of the vessel contrasting of the filling runs. The data of the masking run is subtracted from the combined data sets to obtain final data sets for a three-dimensional presentation of the arterial or the venous vessel system.
摘要翻译：本发明涉及一种用于通过旋转计算机断层摄影在脊椎动物身体的一部分中分离地显示血管系统的血管和/或静脉的方法和装置。在身体部分周围没有造影剂进行断层摄影术的掩蔽运行。然后执行用造影剂的两次填充运行，在第一次填充运行期间血管对比的静脉期发生在第二次灌注运行的血管对比的动脉期期间，反之亦然。来自第一次和第二次灌注运行的数据被组合成来自血管的动脉或静脉期的数据集，与填充运行相反。从组合的数据集中减去掩蔽运行的数据，以获得用于动脉或静脉血管系统的三维呈现的最终数据集。

2. 发明申请

US20070232901A1 Method and device for separate three-dimensional presentation of arteries and veins in a part of body 有权
标题翻译：用于在身体的一部分中单独的立体呈现动脉和静脉的方法和装置
公开(公告)号：US20070232901A1
公开(公告)日：2007-10-04
申请号：US11724657
申请日：2007-03-15
申请人： Goetz Benndorf , Klaus Klingenbeck-Regn , Michael Zellerhoff
发明人： Goetz Benndorf , Klaus Klingenbeck-Regn , Michael Zellerhoff
IPC分类号： A61B5/05
CPC分类号： A61B6/481 , A61B6/504
摘要： The invention is directed to a method and a device for separate three-dimensional presentation of arteries and/or veins of a vessel system in a part of the body of a vertebrate by a rotation computer tomography. A masking run of the tomograph is undertaken without contrast media around the part of the body. Then two filling runs with contrast media are executed, with the venous phase of vessel contrasting during the first filling run occurring during the arterial phase of vessel contrasting of the second filling run and vice-versa. The data from the first and second filling run is combined into data sets from the arterial or the venous phases of the vessel contrasting of the filling runs. The data of the masking run is subtracted from the combined data sets to obtain final data sets for a three-dimensional presentation of the arterial or the venous vessel system.
摘要翻译：本发明涉及一种用于通过旋转计算机断层摄影在脊椎动物身体的一部分中分离地显示血管系统的血管和/或静脉的方法和装置。在身体部分周围没有造影剂进行断层摄影术的掩蔽运行。然后执行用造影剂的两次填充运行，在第一次填充运行期间血管对比的静脉期在第二次灌注运行的血管对比的动脉期期间发生，反之亦然。来自第一次和第二次灌注运行的数据被组合成来自血管的动脉或静脉期的数据集，与填充运行相反。从组合的数据集中减去掩蔽运行的数据，以获得用于动脉或静脉血管系统的三维呈现的最终数据集。

3. 发明授权

US07734009B2 Angiographic x-ray diagnostic device for rotation angiography 有权
标题翻译：用于旋转血管造影的血管造影X线诊断装置
公开(公告)号：US07734009B2
公开(公告)日：2010-06-08
申请号：US11284235
申请日：2005-11-21
申请人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nöttling , Ernst-Peter Rührnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Karl Strobel , Karl Wiesent , Michael Zellerhoff
发明人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nöttling , Ernst-Peter Rührnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Karl Strobel , Karl Wiesent , Michael Zellerhoff
IPC分类号： G01N23/083 , H05G1/02
CPC分类号： G06T11/005 , A61B6/466 , A61B6/504 , G06T2211/404
摘要： The invention relates to an angiographic x-ray diagnostic device for rotation angiography with an x-ray emitter which can be moved on a circular path about a patient located on a patient support table, with an image detector unit which can moved on the circular path facing the x-ray emitter, with a digital image system for recording a plurality of projection images by means of rotation angiography, with a device for image processing, by means of which the projection images are reconstructed into a 3D volume image, and with a device for correcting physical effects and/or inadequacies in the recording system such as truncation correction, scatter correction, ring artifact correction, correction of the beam hardening and/or of the low frequency drop for the soft tissue display of projection images and the 3D volume images resulting therefrom.
摘要翻译：本发明涉及一种用X射线发射器进行旋转血管造影的血管造影X射线诊断装置，该X射线发射器可以围绕位于病人支撑台上的患者的圆形路径移动，图像检测器单元可在圆形路径上移动面对x射线发射器，具有用于通过旋转血管造影记录多个投影图像的数字图像系统，具有用于图像处理的装置，通过该装置将投影图像重建成3D体积图像，并且利用用于校正记录系统的物理效应和/或不足的装置，例如用于投影图像的软组织显示的截断校正，散射校正，环形伪影校正，光束硬化的校正和/或低频率下降以及3D体积由此产生的图像。

4. 发明申请

US20060120507A1 Angiographic x-ray diagnostic device for rotation angiography 有权
标题翻译：用于旋转血管造影的血管造影X线诊断装置
公开(公告)号：US20060120507A1
公开(公告)日：2006-06-08
申请号：US11284235
申请日：2005-11-21
申请人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nottling , Ernst-Peter Ruhrnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Strobel , Karl Wiesent , Michael Zellerhoff
发明人： Thomas Brunner , Klaus Klingenbeck-Regn , Michael Maschke , Alois Nottling , Ernst-Peter Ruhrnschopf , Bernhard Scholz , Bernd Schreiber , Norbert Strobel , Karl Wiesent , Michael Zellerhoff
IPC分类号： G01N23/04
CPC分类号： G06T11/005 , A61B6/466 , A61B6/504 , G06T2211/404
摘要： The invention relates to an angiographic x-ray diagnostic device for rotation angiography with an x-ray emitter which can be moved on a circular path about a patient located on a patient support table, with an image detector unit which can moved on the circular path facing the x-ray emitter, with a digital image system for recording a plurality of projection images by means of rotation angiography, with a device for image processing, by means of which the projection images are reconstructed into a 3D volume image, and with a device for correcting physical effects and/or inadequacies in the recording system such as truncation correction, scatter correction, ring artifact correction, correction of the beam hardening and/or of the low frequency drop for the soft tissue display of projection images and the 3D volume images resulting therefrom.
摘要翻译：本发明涉及一种用X射线发射器进行旋转血管造影的血管造影X射线诊断装置，该X射线发射器可以围绕位于病人支撑台上的患者的圆形路径移动，图像检测器单元可在圆形路径上移动面对x射线发射器，具有用于通过旋转血管造影记录多个投影图像的数字图像系统，具有用于图像处理的装置，通过该装置将投影图像重建成3D体积图像，并且利用用于校正记录系统的物理效应和/或不足的装置，例如用于投影图像的软组织显示的截断校正，散射校正，环形伪影校正，光束硬化的校正和/或低频率下降的3D体积由此产生的图像。

5. 发明授权

US07953267B2 Method for the three-dimensional representation of a structure influenced by a periodic process, and medical imaging system 有权
标题翻译：用于周期性过程影响的结构的三维表示的方法，以及医学成像系统
公开(公告)号：US07953267B2
公开(公告)日：2011-05-31
申请号：US11881379
申请日：2007-07-26
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
IPC分类号： G06K9/00 , G06K9/32 , A61B6/00 , G01N23/00 , G21K1/12 , H05G1/60 , H05G1/10
CPC分类号： G01N23/046 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/541 , G01N2223/419 , G01N2223/612
摘要： There is described a method for a periodic and three-dimensional representation of a periodically variable structure. A number of rotation images is generated for this purpose. The required rotations relating to the same event of the periodic process are started at intervals offset by a defined angle. From the rotation images, new image series are assembled with which three-dimensional representations relating to different phase ranges of the period are reconstructed.
摘要翻译：描述了周期性和三维表示周期性变化结构的方法。为此目的生成多个旋转图像。与周期性过程的相同事件有关的所需旋转以间隔偏移定义的角度开始。从旋转图像，组装新图像系列，重建与周期的不同相位范围有关的三维表示。

6. 发明申请

US20100246916A1 Method and apparatus for generating a functional data set of a perfused region of the human or animal body 有权
标题翻译：用于产生人或动物体的灌注区域的功能数据集的方法和装置
公开(公告)号：US20100246916A1
公开(公告)日：2010-09-30
申请号：US12729269
申请日：2010-03-23
申请人： Yu Deuerling-Zheng , Thomas Redel , Michael Zellerhoff
发明人： Yu Deuerling-Zheng , Thomas Redel , Michael Zellerhoff
IPC分类号： G06K9/00 , G01N23/04
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , A61B6/5235 , A61B2090/364
摘要： A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
摘要翻译：提出了一种用于产生人体或动物身体的灌注区域的至少一个功能数据集的方法和装置。提供第一图像数据组，其包括在将造影剂注射到供应该区域的第一动脉之前和之后的不同时间记录的灌注区域的至少两个图像。提供第二图像数据集，其包括在将造影剂注射到供应该区域的第二动脉之前和之后的不同时间记录的灌注区域的至少两个图像。通过基于来自第一图像数据集的至少一个灌注参数的基于像素的计算来生成第一功能数据集。通过基于来自第二图像数据集的至少一个灌注参数的基于像素的计算来生成第二功能数据集。

7. 发明申请

US20090092225A1 Method for the three-dimensional representation of a moving structure by a tomographic method 有权
标题翻译：通过断层摄影法对移动结构进行三维表示的方法
公开(公告)号：US20090092225A1
公开(公告)日：2009-04-09
申请号：US12221938
申请日：2008-08-07
申请人： Jan Boese , Wolfgang Harer , Michael Zellerhoff
发明人： Jan Boese , Wolfgang Harer , Michael Zellerhoff
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/412 , G06T2211/436
摘要： The invention relates to a method for a three-dimensional representation of a moving structure by a tomographic method, in which during one recording pass a series of projection recordings is registered by an imaging unit at different recording angles between a start position and an end position, it being possible to reconstruct three-dimensional image data from the projection recordings with the following steps: a) generation of tomosynthesis projection recordings along a tomosynthesis scanning path; b) interpolation of the data of the tomosynthesis projection recordings in accordance with an interpolation algorithm in order to generate a projection data set; c) use of a tomosynthesis reconstruction method on the projection data set in order to generate a tomosynthesis volume image; d) repetition of steps b) and c) for all times of interest, and e) display of tomosynthesis representations from the tomosynthesis volume images.
摘要翻译：本发明涉及一种用于通过断层摄影方法对运动结构进行三维表示的方法，其中在一次记录通过期间，成像单元以起始位置和结束位置之间的不同记录角度登记一系列投影记录可以通过以下步骤从投影记录重建三维图像数据：a）沿着断层合成扫描路径生成断层合成投影记录; b）根据插值算法对所述断层合成投影记录的数据进行插值，以生成投影数据集; c）在投影数据集上使用断层合成重建方法，以便产生断层合成体积图像; d）对所有感兴趣的时间重复步骤b）和c），以及e）从断层合成体积图像显示断层合成表示。

8. 发明授权

US09164046B2 Method for a three-dimensional representation of a moving structure 有权
公开(公告)号：US09164046B2
公开(公告)日：2015-10-20
申请号：US12221942
申请日：2008-08-07
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
IPC分类号： A61B6/00 , G01N23/04
CPC分类号： G01N23/046 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/504 , A61B6/507 , A61B6/541 , G01N2223/419
摘要： The invention relates to a method for three-dimensional representation of a moving structure by a tomographical method. Projection images are recorded by an image recording unit during a rotational run from recording angles between a start angle and an end angle, with a three-dimensional image data reconstructed from the projection images, with a first perfusion measurement with a first contrast agent injection and a first rotational run and with a further perfusion measurement with a further contrast agent injection and a further rotational run, which is started after the preceding perfusion measurement has concluded, with the start time and/or the start angle of the additional rotational run deviating from one another in respect of the time of the contrast agent injection. The method enables a functional three-dimensional time-resolved imaging of perfusion processes with the aid of flexible C-arm x-ray devices, which allow a functional imaging in an interventional environment.

9. 发明授权

US08054941B2 Method for the production of angiography recordings 有权
标题翻译：生产血管造影记录的方法
公开(公告)号：US08054941B2
公开(公告)日：2011-11-08
申请号：US12507818
申请日：2009-07-23
申请人： Jan Boese , Yu Deuerling-Zheng , Michael Zellerhoff
发明人： Jan Boese , Yu Deuerling-Zheng , Michael Zellerhoff
IPC分类号： H05G1/64 , H05G1/60 , H05G1/58 , G01N23/083
CPC分类号： A61B6/504 , A61B5/055 , A61B6/4458 , A61B6/481 , A61B6/488 , A61B6/541
摘要： The invention relates to a method for the production of angiography recordings. First, a mask image is recorded with a first modality. A contrast medium is injected after the first recording. A control image is recorded with a second modality after the injection of the contrast medium. A spreading of the contrast medium is determined based on the images and the control of subsequent recordings is analyzed. A recording criterion is checked to determine whether the recording criterion has been achieved. If it has not been achieved, the control image is repeatedly recorded for repeatedly determining the spreading of the contrast medium. If it has been achieved, a contrast image is recorded with the first modality and the mask image and the contrast image are processed and analyzed.
摘要翻译：本发明涉及一种生产血管造影记录的方法。首先，以第一模式记录掩模图像。在第一次记录之后注射造影剂。在注射造影剂之后，以第二模态记录控制图像。基于图像确定造影剂的扩展，并分析后续记录的控制。检查记录标准以确定是否已经实现了记录标准。如果还没有实现，则重复记录控制图像以重复确定造影剂的扩展。如果已经实现，则用第一模态记录对比度图像，并且处理和分析掩模图像和对比度图像。

10. 发明授权

US07558372B2 Method and device for the separate three-dimensional representation of the arterial and venous vascular system using C-arm angiography systems 有权
标题翻译：使用C臂血管造影系统的动脉和静脉血管系统的单独三维表示的方法和装置
公开(公告)号：US07558372B2
公开(公告)日：2009-07-07
申请号：US11897373
申请日：2007-08-30
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
IPC分类号： H05G1/64
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/481
摘要： The invention relates to a method and a device for the separate three-dimensional representation of arteries and/or veins in a vascular system of the body by means of a C-arm biplanar system having two C-arms, which can each record a sequence of x-ray images from different projection angles during a mask or filler pass. With the filler pass, both C-arms record x-ray images, so that the x-ray images of the filler pass can be combined to form a first data record, which contains x-ray images from the arterial phase of the vascular contrasting and/or to form a second data record, which contains x-ray images from the venous phase of the vascular contrasting. This enables the arterial and venous phases to be reconstructed separately.
摘要翻译：本发明涉及一种用于通过具有两个C形臂的C臂双平面系统在身体的血管系统中分离地三维表示动脉和/或静脉的方法和装置，其可以记录一个序列在掩模或填充物通过期间，来自不同投影角度的X射线图像。利用填充通道，两个C臂记录X射线图像，使得填充通路的x射线图像可以组合以形成第一数据记录，其包含来自血管对比的动脉期的X射线图像和/或形成第二数据记录，其包含来自血管造影的静脉期的X射线图像。这使得能够分开重建动脉和静脉期。

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