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1. 发明申请

US20080262519A1 COMPOSITIONS AND METHODS FOR JOINING NON-CONJOINED LUMENS 有权
标题翻译：用于接合非结合光的组合物和方法
公开(公告)号：US20080262519A1
公开(公告)日：2008-10-23
申请号：US11962077
申请日：2007-12-20
申请人： Geoffrey C. GURTNER , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon M. Saul , C. Travis Rappleye , Evgenia Mandrusov
发明人： Geoffrey C. GURTNER , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon M. Saul , C. Travis Rappleye , Evgenia Mandrusov
IPC分类号： A61B17/11
CPC分类号： A61B17/00491 , A61B17/04 , A61B17/11 , A61B17/12022 , A61B17/1204 , A61B17/12109 , A61B17/12186 , A61B17/1219 , A61B17/122 , A61B17/1227 , A61B2017/1103 , A61B2017/1107
摘要： Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique
摘要翻译：公开了用于将非结合腔内连接在患者体内（包括血管内腔）的组合物，方法和试剂盒。更具体地，在各个方面，本发明提供了用于连接这种非结合腔的组合物，方法和试剂盒，包括通常需要显微手术技术的小腔

2. 发明授权

US08608760B2 Compositions and methods for joining non-conjoined lumens 有权
标题翻译：用于连接非结合腔的组合物和方法
公开(公告)号：US08608760B2
公开(公告)日：2013-12-17
申请号：US11962077
申请日：2007-12-20
申请人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
发明人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
IPC分类号： A61B17/08
CPC分类号： A61B17/00491 , A61B17/04 , A61B17/11 , A61B17/12022 , A61B17/1204 , A61B17/12109 , A61B17/12186 , A61B17/1219 , A61B17/122 , A61B17/1227 , A61B2017/1103 , A61B2017/1107
摘要： Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
摘要翻译：公开了用于将非结合腔内连接在患者体内（包括血管内腔）的组合物，方法和试剂盒。更具体地，在各个方面，本发明提供了用于连接这种非结合腔的组合物，方法和试剂盒，包括通常需要显微外科技术的小腔。

3. 发明授权

US08172861B2 Compositions and methods for joining non-conjoined lumens 有权
标题翻译：用于连接非结合腔的组合物和方法
公开(公告)号：US08172861B2
公开(公告)日：2012-05-08
申请号：US12340586
申请日：2008-12-19
申请人： Gerald G. Fuller , C. Travis Rappleye , Evgenia Mandrusov
发明人： Gerald G. Fuller , C. Travis Rappleye , Evgenia Mandrusov
IPC分类号： A61B17/08 , A61F13/00 , A61K9/14
CPC分类号： A61L27/14
摘要： Sol-gel compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides thermoreversible sol-gel compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
摘要翻译：溶胶 - 凝胶组合物，方法和用于将非结合腔体连接在患者体内（包括血管内腔）的试剂盒。更具体地，在各个方面，本发明提供了用于连接这种非结合腔的热可逆溶胶 - 凝胶组合物，方法和试剂盒，包括通常需要显微外科技术的小腔。

4. 发明申请

US20090187199A1 COMPOSITIONS AND METHODS FOR JOINING NON-CONJOINED LUMENS 有权
标题翻译：用于接合非结合光的组合物和方法
公开(公告)号：US20090187199A1
公开(公告)日：2009-07-23
申请号：US12340588
申请日：2008-12-19
申请人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
发明人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
IPC分类号： A61B17/11 , A61B17/08 , A61J1/00
CPC分类号： A61B17/00491 , A61B17/04 , A61B17/11 , A61B17/122 , A61B17/1227 , A61B2017/1103 , A61B2017/1107
摘要： Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
摘要翻译：公开了用于将非结合腔内连接在患者体内（包括血管内腔）的组合物，方法和试剂盒。更具体地，在各个方面，本发明提供了用于连接这种非结合腔的组合物，方法和试剂盒，包括通常需要显微外科技术的小腔。

5. 发明申请

US20090162438A1 COMPOSITIONS AND METHODS FOR JOINING NON-CONJOINED LUMENS 有权
标题翻译：用于接合非结合光的组合物和方法
公开(公告)号：US20090162438A1
公开(公告)日：2009-06-25
申请号：US12340586
申请日：2008-12-19
申请人： Gerald G. Fuller , C. Travis Rappleye , Evgenia Mandrusov
发明人： Gerald G. Fuller , C. Travis Rappleye , Evgenia Mandrusov
IPC分类号： A61K9/10 , A61B17/11 , A61K31/727
CPC分类号： A61L27/14
摘要： Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique
摘要翻译：公开了用于将非结合腔内连接在患者体内（包括血管内腔）的组合物，方法和试剂盒。更具体地，在各个方面，本发明提供了用于连接这种非结合腔的组合物，方法和试剂盒，包括通常需要显微手术技术的小腔

6. 发明授权

US08197499B2 Compositions and methods for joining non-conjoined lumens 有权
公开(公告)号：US08197499B2
公开(公告)日：2012-06-12
申请号：US12340588
申请日：2008-12-19
申请人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
发明人： Geoffrey C. Gurtner , Gerald G. Fuller , Michael T. Longaker , Jayakumar Rajadas , Gordon Saul , C. Travis Rappleye , Evgenia Mandrusov
IPC分类号： A61B17/08
CPC分类号： A61B17/00491 , A61B17/04 , A61B17/11 , A61B17/122 , A61B17/1227 , A61B2017/1103 , A61B2017/1107
摘要： Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.

7. 发明授权

US08227574B2 Collagen materials, films and methods of making same 有权
标题翻译：胶原材料，胶片及其制作方法
公开(公告)号：US08227574B2
公开(公告)日：2012-07-24
申请号：US11951324
申请日：2007-12-05
申请人： Mikhail Vitoldovich Paukshto , David Harwood McMurtry , Gerald G. Fuller , Yuri Alexandrovich Bobrov , John E. Kirkwood
发明人： Mikhail Vitoldovich Paukshto , David Harwood McMurtry , Gerald G. Fuller , Yuri Alexandrovich Bobrov , John E. Kirkwood
IPC分类号： A61K38/17
CPC分类号： C07K14/78 , Y10T428/24479 , Y10T428/24612
摘要： In general, the present invention is related to collagen compositions and thin films, and to methods of making and using the same. In some embodiments, the present invention is directed to “woven pattern” or “basket pattern” collagen compositions and thin films, and methods of making.
摘要翻译：通常，本发明涉及胶原组合物和薄膜，以及制造和使用它们的方法。在一些实施方案中，本发明涉及“编织图案”或“筐形图案”胶原组合物和薄膜以及制备方法。

8. 发明申请

US20110151563A1 Collagen Materials, Films and Methods of Making Same 有权
标题翻译：胶原材料，薄膜及其制作方法
公开(公告)号：US20110151563A1
公开(公告)日：2011-06-23
申请号：US11951324
申请日：2007-12-05
申请人： Mikhail Vitoldovich Paukshto , David Harwood McMurtry , Gerald G. Fuller , Yuri Alexandrovich Bobrov , John E. Kirkwood
发明人： Mikhail Vitoldovich Paukshto , David Harwood McMurtry , Gerald G. Fuller , Yuri Alexandrovich Bobrov , John E. Kirkwood
IPC分类号： C12N5/00 , B32B3/30 , B29C39/04 , B82Y5/00
CPC分类号： C07K14/78 , Y10T428/24479 , Y10T428/24612
摘要： In general, the present invention is related to collagen compositions and thin films, and to methods of making and using the same. In some embodiments, the present invention is directed to “woven pattern” or “basket pattern” collagen compositions and thin films, and methods of making.
摘要翻译：通常，本发明涉及胶原组合物和薄膜，以及制造和使用它们的方法。在一些实施方案中，本发明涉及“编织图案”或“筐形图案”胶原组合物和薄膜以及制备方法。

9. 发明申请

US20100227043A1 Oriented collagen gel 有权
标题翻译：定向胶原凝胶
公开(公告)号：US20100227043A1
公开(公告)日：2010-09-09
申请号：US12660702
申请日：2010-03-02
申请人： Gerald G. Fuller , John E. Kirkwood
发明人： Gerald G. Fuller , John E. Kirkwood
IPC分类号： A61L33/14
CPC分类号： B05D5/00 , A61L27/24 , A61L27/50 , C08J5/00 , C08J2389/00 , C08L89/06
摘要： Techniques for the production of flow-oriented collagen gels using hydrodynamics to influence the assembly of collagen fibers. Highly concentrated monomeric solutions of collagen are subjected to shear and extensional flow as they are drawn onto a substrate to induce fibrillogenesis under a high Ph buffer. The produced gel captures the flow induced ordering of molecular collagen upon fibril formation. The depositing or the induction of fibrillogenosis occurs without the application of a magnetic field to the concentration of collagen. These highly oriented 3D scaffolds are capable inducing contact guidance and guiding mammalian cell growth. The collagen fibers mimic the construction of in vivo fibers with the characteristic D-periodicity and the integrin receptors on the fibroblasts respond to this organization. The industrial applications of three-dimensional collagen gels as a biomaterial are widespread from drug delivery to burn repair or tissue engineering system.
摘要翻译：使用流体动力学制造流动性胶原凝胶来影响胶原纤维的组装的技术。胶体的高度浓缩的单体溶液经受剪切和拉伸流动，因为它们被吸引到基底上以在高Ph缓冲液下诱导原纤维生成。所产生的凝胶捕获原纤维形成时分子胶原的流动引发排序。原发性纤维化的沉积或诱导发生在没有对胶原浓度施加磁场的情况下。这些高度定向的3D支架能够诱导接触引导和引导哺乳动物细胞生长。胶原纤维模拟具有特征性D周期的体内纤维的构建，并且成纤维细胞上的整联蛋白受体对该组织作出反应。三维胶原凝胶作为生物材料的工业应用从药物输送到烧伤修复或组织工程系统是广泛的。

10. 发明授权

US5115669A Measuring shear viscosity of fluids 失效
标题翻译：测量流体的剪切粘度
公开(公告)号：US5115669A
公开(公告)日：1992-05-26
申请号：US593231
申请日：1990-10-05
申请人： Gerald G. Fuller , Ronald F. Garritano , Paul Mode
发明人： Gerald G. Fuller , Ronald F. Garritano , Paul Mode
IPC分类号： G01N11/04 , G01N33/32
CPC分类号： G01N11/04 , G01N33/32
摘要： Apparatus and method for measuring the shear viscosity of a fluid urges sample fluid through a gap between a sleeve having an axial passage and a pin extending axially into the passage in the sleeve to subject the sample fluid to shear while measuring the axial force tending to move the pin and the sleeve axially away from one another, the axial force being indicative of the shear viscosity of the sample fluid.
摘要翻译：用于测量流体的剪切粘度的装置和方法通过具有轴向通道的套筒和轴向延伸到套筒中的通道中的间隙之间的间隙来促使样品流体受到样品流体的剪切，同时测量倾向于移动的轴向力销和套筒轴向地彼此远离，轴向力表示样品流体的剪切粘度。

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