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    • 1. 发明申请
    • Measurement of Mitochondrial Membrane Potential to Assess Organ Dysfunction
    • 线粒体膜电位的测定以评估器官功能障碍
    • US20120171716A1
    • 2012-07-05
    • US13389861
    • 2010-08-11
    • Zhaoli SunGeorge Williams
    • Zhaoli SunGeorge Williams
    • C12Q1/02
    • G01N33/5005G01N2800/245
    • The present invention relates to the field of organ transplantation. More specifically, the present invention provides methods for predicting organ function after transplantation. In certain embodiments, the method comprises measuring mitochondrial membrane potential from a biopsy sample from the donor organ. The present invention is also applicable to organ dysfunction in general. More specifically, the methods of the present invention may be useful in formulating prognoses for patients with acute or chronic organ dysfunction due to ischemia, infection, drug injury or age. In this rapid procedure, only small samples of tissue are required, enabling the clinical application of mitochondrial function previously thought impractical.
    • 本发明涉及器官移植领域。 更具体地,本发明提供了用于预测移植后器官功能的方法。 在某些实施方案中,该方法包括从供体器官的活组织检查样品测量线粒体膜电位。 本发明一般也适用于器官功能障碍。 更具体地说,本发明的方法可用于为由于缺血,感染,药物损伤或年龄引起的急性或慢性器官功能障碍的患者的预后。 在这个快速的过程中,只需要小的组织样本,从而使线粒体功能的临床应用以前认为是不切实际的。
    • 5. 发明申请
    • Heat exchanger tube support
    • 热交换器管支撑
    • US20050109494A1
    • 2005-05-26
    • US10995664
    • 2004-11-23
    • George WilliamsWilliam PritzPeter PritzThomas PritzDorothy Pritz
    • George WilliamsWilliam PritzPeter PritzThomas PritzDorothy Pritz
    • F28F9/013F28F9/00
    • F28F9/0135
    • A tube support device is presented. The present invention includes at least two first plates and at least two second plates each having a plurality of slots mutually arranged and aligned so as to allow four or more plates to interlock and form a grid of depth-wise planar extent thereby providing at least one square-shaped opening. Each first plate and each second plate have a plurality of u-shaped nodules. At least one u-shaped nodule along each first plate and along each second plate extends into each square-shaped opening. U-shaped nodules are disposed parallel to and contacting a tube passing through each square-shaped opening. The grid is surrounded by a fluid with a flow field parallel to each tube and may include a secondary flow field crosswise disposed with respect to each tube. In yet another embodiments, the present invention is positioned within a shell and tube heat exchanger so as to support a plurality of tubes passing there through.
    • 提供管支撑装置。 本发明包括至少两个第一板和至少两个第二板,每个第二板具有相互排列和对准的多个槽,以便允许四个或更多个板互锁并形成一个深度方向的平面盘区,从而提供至少一个 方形开口。 每个第一板和每个第二板具有多个u形结节。 沿着每个第一板和沿着每个第二板的至少一个u形结节延伸到每个方形开口中。 U形结节平行于通过每个方形开口的管接触。 格栅由流体围绕,流体具有平行于每个管的流场,并且可以包括相对于每个管道横向设置的二次流场。 在另一个实施例中,本发明定位在壳管式热交换器内,以支撑通过其的多个管。
    • 6. 发明申请
    • Audible warning device for a motorcycle
    • 摩托车的声音报警装置
    • US20050080526A1
    • 2005-04-14
    • US10685212
    • 2003-10-14
    • George WilliamsBrandon Tusing
    • George WilliamsBrandon Tusing
    • B60R16/023G06F19/00
    • B60R16/0232
    • The present invention is adapted to sound an audible alarm if the operator of a motorcycle stops the engine with the shut off switch and leaves the ignition on. The alarm will sound once the oil pressure falls to 0 or below a predetermined level. The present invention is also useful for notifying the operator of a loss of oil pressure during operation, indicating either that the engine has stopped running, such as by stalling, or oil pressure has dropped below the minimum safe operating level due to a leak or mechanical defect. The invention is also useful during startup of a motorcycle to warn of a problem with the lubrication system. When the engine is started, the oil pressure audible alarm will sound until the engine oil pressure has exceeded the minimum pressure.
    • 如果摩托车的操作员用关闭开关停止发动机并且使点火开启,本发明适于发出声音报警。 一旦油压降至0或低于预定水平,报警器将发出声音。 本发明还可用于在操作期间通知操作者油压损失,指示发动机已经停止运行,例如由于失速或油压已经由于泄漏或机械而已经降到最低安全操作水平以下 缺陷。 本发明在启动摩托车以警告润滑系统的问题时也是有用的。 当发动机启动时,油压声音报警器将发出声音,直到发动机机油压力超过最小压力。
    • 7. 发明授权
    • Matching hat and scarf
    • 匹配的帽子和围巾
    • US06185749B1
    • 2001-02-13
    • US09407403
    • 1999-09-28
    • George Williams
    • George Williams
    • A42B124
    • A42B7/00A41D23/00A42B1/041A42B1/045A42B1/24
    • A hat and scarf that is made from coordinating material. A band extends around the circumference of the bottom of the hat and secures it to one's head. A loop is secured to the top of the hat. Each end of the loop is stitched to the hat top, thereby creating a small opening between the hat and the loop. At the rear of the hat, a band is secured at both ends by means of a fastener. The fastener is preferably a button or snap, thereby allowing the band to be easily attached or detached from the hat. A strand of coordinating material extends along the rear of the hat. It is fitted through the loop at the hat top and is secured under the band, consequently leaving two ends of the strand dangling from the bottom of the hat. The scarf is made from a flexible material that drapes loosely over one's neck. It is made from the same material as the hat, thereby creating a matching set.
    • 由协调材料制成的帽子和围巾。 带子围绕着帽子底部的圆周延伸,并将其固定在头顶上。 一个环被固定在帽子的顶部。 环的每个端部被缝合到帽子顶部,从而在帽子和环之间形成小的开口。 在帽子的后部,通过紧固件将带固定在两端。 紧固件优选地是按钮或卡扣,从而允许带容易地从帽子附接或分离。 一串协调材料沿着帽子的后部延伸。 它通过帽子顶部的环路安装,并固定在带子下面,从而使绞线的两端悬挂在帽子的底部。 围巾由柔软的材料制成,宽松地覆盖在脖子上。 它由与帽子相同的材料制成,从而创建一个匹配的组合。