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1. 发明授权

US08538556B2 Enhanced implantable antenna method 有权
标题翻译：增强植入式天线方法
公开(公告)号：US08538556B2
公开(公告)日：2013-09-17
申请号：US12060818
申请日：2008-04-01
申请人： George W. Keilman , Timothy Johnson
发明人： George W. Keilman , Timothy Johnson
IPC分类号： A61N1/08
CPC分类号： H01Q1/22 , A61N1/37229 , Y10T29/49016 , Y10T29/53204
摘要： As described herein vascular anchoring systems are used to position an implant in a vascular area such as a bifurcated vasculature with relatively high fluid flow, for instance, in an area of a pulmonary artery with associated left and right pulmonary arteries. Implementations include an anchoring trunk member having a first anchoring trunk section and a second anchoring trunk section. Further implementations include a first anchoring branch member extending from the anchoring trunk member. Still further implementations include a second anchoring branch member extending from the anchoring trunk member.
摘要翻译：如本文所描述的，血管锚定系统用于将植入物定位在诸如具有相对高的流体流动的分叉血管的血管区域中，例如在具有相关联的左肺动脉和右肺动脉的肺动脉的区域中。实施方案包括具有第一锚固干线部分和第二锚固干线部分的锚固干线部件。另外的实施方案包括从锚固树干构件延伸的第一锚定分支构件。另外的实施方式包括从锚固树干构件延伸的第二锚定分支构件。

2. 发明授权

US08142359B2 Enhanced intraluminal flow measurement method using reference and combined signals 有权
标题翻译：使用参考和组合信号增强管腔内流量测量方法
公开(公告)号：US08142359B2
公开(公告)日：2012-03-27
申请号：US12104966
申请日：2008-04-17
申请人： George W. Keilman , Leigh Bartlett , Timothy Johnson
发明人： George W. Keilman , Leigh Bartlett , Timothy Johnson
IPC分类号： A61B8/06
CPC分类号： A61B5/026 , A61B5/0031 , A61B5/0265 , A61B5/6846 , A61B8/06 , A61B8/12 , A61B8/4472
摘要： An enhanced intraluminal flow measurement system and method is conducive for a low-power ultrasonic system that can use continuous-wave (CW) Doppler sensing and wireless RF telemetry. Applications include measurement of blood flow in situ in living organisms. Implementations include an extraluminal component located outside of a body, such as a human or animal body, containing a lumen. The extraluminal component can be wirelessly coupled via an RF magnetic field or other RF field to an implantable intraluminal component. The intraluminal component (i.e. implant) is implanted inside of the lumen of the body such as a heart or elsewhere in a vasculature (such as in a dialysis shunt). The intraluminal component can telemeter, via RF electromagnetic signals, flow data directly out of the body housing the intraluminal component to be received by the extraluminal component.
摘要翻译：增强的管腔内流量测量系统和方法有利于可以使用连续波（CW）多普勒感测和无线RF遥测的低功率超声波系统。应用包括在生物体内原位测量血流。实施方案包括位于身体外部的外阴部件，例如包含内腔的人体或动物体。管腔内部件可以经由RF磁场或其他RF场无线耦合到可植入的管腔内部件。管腔内成分（即植入物）植入体内的腔内，例如心脏或其它脉管系统（如透析分流）中。管腔内成分可以通过射频电磁信号将流量数据直接传送出外壳体内的腔内部件，以便由腔内部件接收。

3. 发明申请

US20090264761A1 ENHANCED INTRALUMINAL FLOW MEASUREMENT SYSTEM USING REFERENCE AND COMBINED SIGNALS 有权
标题翻译：使用参考和组合信号的增强的内部流量测量系统
公开(公告)号：US20090264761A1
公开(公告)日：2009-10-22
申请号：US12104949
申请日：2008-04-17
申请人： George W. Keilman , Leigh Bartlett , Timothy Johnson
发明人： George W. Keilman , Leigh Bartlett , Timothy Johnson
IPC分类号： A61B8/00 , A61B5/00 , A61N1/00
CPC分类号： A61B8/12 , A61B5/0031 , A61B8/06 , A61B8/488
摘要： An enhanced intraluminal flow measurement system and method is conducive for a low-power ultrasonic system that can use continuous-wave (CW) Doppler sensing and wireless RF telemetry. Applications include measurement of blood flow in situ in living organisms. Implementations include an extraluminal component located outside of a body, such as a human or animal body, containing a lumen. The extraluminal component can be wirelessly coupled via an RF magnetic field or other RF field to an implantable intraluminal component. The intraluminal component (i.e. implant) is implanted inside of the lumen of the body such as a heart or elsewhere in a vasculature (such as in a dialysis shunt). The intraluminal component can telemeter, via RF electromagnetic signals, flow data directly out of the body housing the intraluminal component to be received by the extraluminal component.
摘要翻译：增强的管腔内流量测量系统和方法有利于可以使用连续波（CW）多普勒感测和无线RF遥测的低功率超声波系统。应用包括在生物体内原位测量血流。实施方案包括位于身体外部的外阴部件，例如包含内腔的人体或动物体。管腔内部件可以经由RF磁场或其他RF场无线耦合到可植入的管腔内部件。管腔内成分（即植入物）植入体内的腔内，例如心脏或其它脉管系统（如透析分流）中。管腔内成分可以通过射频电磁信号将流量数据直接传送出外壳体内的腔内部件，以便由腔内部件接收。

4. 发明申请

US20090243956A1 ENHANCED IMPLANTABLE HELICAL ANTENNA SYSTEM AND METHOD 有权
标题翻译：增强的可植入式天线系统和方法
公开(公告)号：US20090243956A1
公开(公告)日：2009-10-01
申请号：US12060816
申请日：2008-04-01
申请人： George W. Keilman , Timothy Johnson
发明人： George W. Keilman , Timothy Johnson
IPC分类号： H01Q1/36
CPC分类号： H01Q7/00 , A61N1/37229 , H01Q1/362 , H01Q9/26
摘要： As described herein vascular anchoring systems are used to position an implant in a vascular area such as a bifurcated vasculature with relatively high fluid flow, for instance, in an area of a pulmonary artery with associated left and right pulmonary arteries. Implementations include an anchoring trunk member having a first anchoring trunk section and a second anchoring trunk section. Further implementations include a first anchoring branch member extending from the anchoring trunk member. Still further implementations include a second anchoring branch member extending from the anchoring trunk member.
摘要翻译：如本文所描述的，血管锚定系统用于将植入物定位在诸如具有相对高的流体流动的分叉血管的血管区域中，例如在具有相关联的左肺动脉和右肺动脉的肺动脉的区域中。实施方案包括具有第一锚固干线部分和第二锚固干线部分的锚固干线部件。另外的实施方案包括从锚固树干构件延伸的第一锚定分支构件。另外的实施方式包括从锚固树干构件延伸的第二锚定分支构件。

5. 发明申请

US20090234435A1 VASCULAR ANCHORING SYSTEM AND METHOD 有权
标题翻译：血管锚固系统及方法
公开(公告)号：US20090234435A1
公开(公告)日：2009-09-17
申请号：US12048053
申请日：2008-03-13
申请人： Timothy Johnson , George W. Keilman
发明人： Timothy Johnson , George W. Keilman
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2/848 , A61F2/954 , A61F2/966 , A61F2002/821 , A61F2002/9665 , A61F2220/0008 , A61F2230/0008
摘要： As described herein vascular anchoring systems are used to position an implant in a vascular area such as a bifurcated vasculature with relatively high fluid flow, for instance, in an area of a pulmonary artery with associated left and right pulmonary arteries. Implementations include an anchoring trunk member having a first anchoring trunk section and a second anchoring trunk section. Further implementations include a first anchoring branch member extending from the anchoring trunk member. Still further implementations include a second anchoring branch member extending from the anchoring trunk member.
摘要翻译：如本文所描述的，血管锚定系统用于将植入物定位在诸如具有相对高的流体流动的分叉血管的血管区域中，例如在具有相关联的左肺动脉和右肺动脉的肺动脉的区域中。实施方案包括具有第一锚固干线部分和第二锚固干线部分的锚固干线部件。另外的实施方案包括从锚固树干构件延伸的第一锚定分支构件。另外的实施方式包括从锚固树干构件延伸的第二锚定分支构件。

6. 发明授权

US07568394B1 Enhanced diaphragm for pressure sensing system and method 有权
标题翻译：用于压力传感系统和方法的增强隔膜
公开(公告)号：US07568394B1
公开(公告)日：2009-08-04
申请号：US12109289
申请日：2008-04-24
申请人： George W. Keilman , Timothy Johnson
发明人： George W. Keilman , Timothy Johnson
IPC分类号： G01L7/08
CPC分类号： A61B5/0215 , A61B2562/0247 , A61B2562/028 , G01L19/0046 , G01L19/04
摘要： An enhanced pressure sensing system and method use an external diaphragm to address issues involved with accurate and prolonged measurement of fluid pressure, such as of blood flowing in a vascular structure. Some external diaphragms include a metallized layer or other highly impermeable layer to furnish a high degree of seal at least near to hermetic grade. As temperature of the intermediary fluid changes, the external diaphragm is able to move in a direction that minimizes differential pressure across the external diaphragm over an operational temperature range thereby reducing pressure change of the intermediary fluid due to change in temperature of the intermediary fluid. Relatively smooth hydrodynamic surfaces can be used as well as a bi-layer construction.
摘要翻译：增强的压力感测系统和方法使用外部膜片来解决涉及流体压力的精确和长期测量的问题，例如在血管结构中流动的血液。一些外部隔膜包括金属化层或其它高度不可渗透的层，以至少接近密封级别提供高密度的密封。当中间流体的温度变化时，外部隔膜能够在使操作温度范围内使外部隔膜两端的差压最小化的方向上移动，从而减少由于中间流体的温度变化引起的中间流体的压力变化。可以使用相对平滑的流体动力学表面以及双层结构。

7. 发明申请

US20090093761A1 Medical-procedure assistance device and method with improved optical contrast, and new practitioner-safety, device-fixation, electrode and magnetic treatment and lumen-dilation capabilities 审中-公开
标题翻译：具有改善的光学对比度的医疗手术辅助装置和方法，以及新的从业者 - 安全性，装置固定，电极和磁疗以及管腔扩张能力
公开(公告)号：US20090093761A1
公开(公告)日：2009-04-09
申请号：US11973052
申请日：2007-10-05
申请人： John W. Sliwa , Bryan T. Oronsky , Herbert L. Berman , Neil C. Oronsky , Carol A Tosaya , George W. Keilman
发明人： John W. Sliwa , Bryan T. Oronsky , Herbert L. Berman , Neil C. Oronsky , Carol A Tosaya , George W. Keilman
IPC分类号： A61M5/32
CPC分类号： A61M5/427 , A61B17/3403 , A61B90/30 , A61B2090/309 , A61B2090/373 , A61N1/0452 , A61N1/0456 , A61N1/325 , A61N1/36021
摘要： Many medical procedures, such as needle-sticking, could benefit from an assistive device that improves the optical contrast of externally targeted features and lumens of interest residing in and underneath the skin and/or exposed organ tissues. The inventive inexpensive device and method are useable on such externally targeted features and lumens while also protecting the practitioner and freeing up both of his/her hands, if necessary, to thereby eliminate practitioner self-sticking problems. The present device provides good optical contrast and also provides splash-protection against HIV, hepatitis and other blood-borne diseases. The inventive device method and apparatus may also include vibratory subcutaneous electrical nerve stimulation (TENS), drug-based or heating treatment capabilities for reducing pain, both perceived and real pain, associated with a device guided procedure. Finally, the pain reduction mechanisms have also been found useful for lumen dilation.
摘要翻译：许多医疗程序，例如针刺，可以从辅助装置中获益，该辅助装置改善外部目标特征和驻留在皮肤和/或暴露的器官组织下方的感兴趣的流明的光学对比度。本发明的廉价的装置和方法可用于这样的外部目标特征和流明，同时还保护从业者并且如果需要释放他/她的双手，从而消除从业者自身的问题。本装置提供良好的光学对比度，并且还提供针对艾滋病毒，肝炎和其他血源性疾病的飞溅防护。本发明的装置方法和装置还可以包括振动皮下电神经刺激（TENS），基于药物的或加热处理能力，用于减少与装置引导的过程相关的疼痛，感觉和真实疼痛。最后，还发现减轻疼痛的机制可用于管腔扩张。

8. 发明授权

US06585763B1 Implantable therapeutic device and method 失效
标题翻译：可植入治疗装置及方法
公开(公告)号：US06585763B1
公开(公告)日：2003-07-01
申请号：US09028173
申请日：1998-02-23
申请人： George W. Keilman , George E. Cimochowski
发明人： George W. Keilman , George E. Cimochowski
IPC分类号： A61F206
CPC分类号： A61M37/0092 , A61B5/0031 , A61B5/026 , A61B5/04 , A61B5/4839 , A61B5/6862 , A61B5/6876 , A61B8/04 , A61B8/06 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B8/56 , A61B2560/0219 , A61F2/07 , A61F2250/0001 , A61M1/3656
摘要： A system includes a first coil, a signal source and a first control module. The first control module regulates coupling between the signal source and the first coil. The system also includes an implantable device having a second coil coupled to a therapeutic transducer comprising an ultrasonic transducer. When the first coil is aligned with the second coil, the signal source is able to supply electrical power to the implantable device to enable the therapeutic transducer to operate. The control module is able to activate the therapeutic transducer under the control of a physician.
摘要翻译：系统包括第一线圈，信号源和第一控制模块。第一控制模块调节信号源和第一线圈之间的耦合。该系统还包括具有耦合到包括超声换能器的治疗换能器的第二线圈的可植入装置。当第一线圈与第二线圈对准时，信号源能够向可植入装置供电，以使得治疗传感器能够操作。控制模块能够在医生的控制下激活治疗换能器。

9. 发明授权

US07833265B2 Vascular anchoring system and method 有权
标题翻译：血管锚固系统及方法
公开(公告)号：US07833265B2
公开(公告)日：2010-11-16
申请号：US12048053
申请日：2008-03-13
申请人： Timothy Johnson , George W. Keilman
发明人： Timothy Johnson , George W. Keilman
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2/848 , A61F2/954 , A61F2/966 , A61F2002/821 , A61F2002/9665 , A61F2220/0008 , A61F2230/0008
摘要： As described herein vascular anchoring systems are used to position an implant in a vascular area such as a bifurcated vasculature with relatively high fluid flow, for instance, in an area of a pulmonary artery with associated left and right pulmonary arteries. Implementations include an anchoring trunk member having a first anchoring trunk section and a second anchoring trunk section. Further implementations include a first anchoring branch member extending from the anchoring trunk member. Still further implementations include a second anchoring branch member extending from the anchoring trunk member.
摘要翻译：如本文所描述的，血管锚定系统用于将植入物定位在诸如具有相对高的流体流动的分叉血管的血管区域中，例如在具有相关联的左肺动脉和右肺动脉的肺动脉的区域中。实施方案包括具有第一锚固干线部分和第二锚固干线部分的锚固干线部件。另外的实施方案包括从锚固树干构件延伸的第一锚定分支构件。另外的实施方式包括从锚固树干构件延伸的第二锚定分支构件。

10. 发明申请

US20100233021A1 Systems and methods to deal with health-relevant fouling or plugging depositions and growths 审中-公开
标题翻译：处理与健康有关的结垢或堵塞沉积和生长的系统和方法
公开(公告)号：US20100233021A1
公开(公告)日：2010-09-16
申请号：US12381423
申请日：2009-03-11
申请人： John W. Sliwa , George W. Keilman , Bryan T. Oronsky , Carol A. Tosaya , Herbert L. Berman
发明人： John W. Sliwa , George W. Keilman , Bryan T. Oronsky , Carol A. Tosaya , Herbert L. Berman
IPC分类号： A61L2/10 , A61L2/03 , A61L2/025 , A61N1/32
CPC分类号： A61M25/0017 , A61B90/70 , A61M27/00 , A61M37/00 , A61M2025/0019 , A61N1/205 , A61N1/32 , A61N1/40
摘要： Disclosed are methods of inhibiting, avoiding or destroying existing, potential or incipient biodeposits, biofilms or pathogens any of (a) in or on a living body including in or on a medical device or implement placed, inserted or insertable in the body, (b) in, on or in contact with an ex vivo bodily tissue or fluid, or (c) in, on or in contact with a medium or matter to be consumed, ingested by or exposed to a living being or entity. Also disclosed are medical devices, implements, and prostheses that can be kept in a safe defouled, pathogen-free or pathogen-reduced condition with the help of an electric field(s). Also disclosed are medical or industrial devices, implements, equipment-articles and storage/handling-entities that can be kept in a safely defouled, pathogen-free or pathogen-reduced condition with the help of a membrane or orifice that has one or more of the antifouling or antipathogenic attributes.
摘要翻译：公开了抑制，避免或破坏现有的，潜在的或初期的生物沉积物，生物膜或病原体（a）在生物体内或之上的生物体，包括在放置，插入或插入体内的医疗装置或器具中或之上，（b））在离体身体组织或流体接触或接触时，或（c）在要消费的介质或物质中或与其接触或摄入或暴露于活体或实体时。还公开了医疗装置，器具和假体，其可以在电场的帮助下保持在安全的防污染，无病原体或病原体减少的状态。还公开了医疗或工业装置，器具，设备制品和储存/处理实体，其可以在具有一个或多个以下的膜或孔的帮助下保持在安全脱钩，无病原体或病原体减少的状态防污或抗病原性。

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