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    • 2. 发明专利
    • Coaggregation inhibitor for oral cavity bacteria and composition for oral cavity compounded therewith
    • 用于口腔肠细菌的组合抑制剂及其复合物的口腔组合物
    • JP2011063556A
    • 2011-03-31
    • JP2009216849
    • 2009-09-18
    • Gc Corp株式会社ジーシー
    • SATO TAKUYAYASUDA EMIKOTAKAYAMA KAZUTO
    • A61K36/18A61K8/97A61K36/00A61K36/28A61K36/53A61K36/60A61K36/71A61K36/73A61P1/02A61Q11/00
    • PROBLEM TO BE SOLVED: To provide an agent important for radically and effectively preventing periodontosis and dental caries and for inhibiting or delaying the progress or curing the diseases, and inhibiting all coaggregation of initial colonization bacteria and bacteria of genus Fusobacterium, bacteria of genus Fusobacterium and periodontosis-relating bacteria, and initial colonization bacteria and periodontosis-relating bacteria, and to provide an oral cavity composition compounded with the agent.
      SOLUTION: The coaggregation inhibitor for oral cavity bacteria comprises dried powder and/or solvent extract of a plant selected from (A) one or more plants selected from Paeonia lactiflora, Humulus lupulus and Hamamelis virginiana, and/or (B) a combination of one or more plants selected from Crataegus cuneata, Crataegus laevigata and Aesculus hippocastanum with one or more plant selected from Salvia officinalis, Anthemis nobilis and Mentha piperita and/or (C) a combination of Houttuynia cordata with one or more plants selected from Crataegus cuneata, Crataegus laevigata and Aesculus hippocastanum.
      COPYRIGHT: (C)2011,JPO&INPIT
    • 要解决的问题:提供一种重要的用于彻底有效预防牙周病和龋齿并抑制或延缓进展或治愈疾病,以及抑制初始定殖细菌和杆菌属细菌的所有聚集的重要试剂, Fusobacterium属和牙周病相关细菌,以及初始定殖细菌和牙周病相关细菌,并提供与该药剂混合的口腔组合物。 解决方案:用于口腔细菌的共聚抑制剂包括选自(A)一种或多种选自芍药芍药,葎草和金缕梅的植物的干粉和/或溶剂提取物和/或(B) 一种或多种选自Crataegus cuneata,Crataegus laevigata和Eesculus hippocastanum的植物与选自Salvia officinalis,Anthemis nobilis和Mentha piperita的一种或多种植物和/或(C)鱼腥菜与选自Crataegus的一种或多种植物的组合的组合 une ata,山楂和七叶树(Eesculus hippocastanum)。 版权所有(C)2011,JPO&INPIT
    • 3. 发明专利
    • Dental x-ray imaging paste composition
    • 牙齿X射线成像胶料组合物
    • JP2008189576A
    • 2008-08-21
    • JP2007024355
    • 2007-02-02
    • Gc Corp株式会社ジーシー
    • LAURENCE J WALSHKATO SHINICHIKARIYA SHUJISATO TAKUYA
    • A61K6/097A61K49/04
    • PROBLEM TO BE SOLVED: To obtain a dental X-ray imaging paste composition that is simply removed after roentgenography, eliminates a complicated procedure due to an operation of merely filling a pasty composition, nevertheless has a sufficient X-ray imaging property even with a small amount.
      SOLUTION: The dental X-ray imaging paste composition comprises (a) 3-25 wt.% of a polyhydric alcohol, (b) 0.5-10 wt.% of a powdery polymer substance soluble or swellable in the polyhydric alcohol and water, (c) 10-30 wt.% of water and (d) 25-80 wt.% of a powdery X-ray contrast medium. The total weight of (a) the polyhydric alcohol and (c) water is 3-25 times the weight of (b) the powdery polymer substance. The dental X-ray imaging paste composition comprises further (e) 0.01-5 wt.% of a fluorine compound and (f) ≤15 wt.% of one or more kinds selected from a buffer, sweetener, colorant, preservative, antiseptic, mildewproofing agent, pH adjuster and perfume as additives.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:为了获得在扫描后简单地除去的牙科X射线成像膏组合物,由于仅填充糊状组合物的操作而消除了复杂的过程,然而具有足够的X射线成像特性,甚至 少量。 牙科X射线成像膏组合物包含(a)3-25重量%的多元醇,(b)0.5-10重量%的在多元醇中可溶或溶胀的粉末状聚合物物质,和 水,(c)10-30重量%的水和(d)25-80重量%的粉末状X射线造影剂。 (a)多元醇和(c)水的总重量为(b)粉末聚合物物质重量的3-25倍。 牙科X射线成像膏组合物还包含(e)0.01-5重量%的氟化合物和(f)≤15重量%的选自缓冲剂,甜味剂,着色剂,防腐剂,防腐剂, 防霉剂,pH调节剂和香料作为添加剂。 版权所有(C)2008,JPO&INPIT
    • 5. 发明专利
    • Composition for cleaning inside of oral cavity
    • 用于清洁口腔内的组合物
    • JP2005002107A
    • 2005-01-06
    • JP2004150591
    • 2004-05-20
    • Gc Corp株式会社ジーシー
    • ABIRU MASAOSATO TAKUYA
    • A61K8/96A61K8/20A61K8/23A61K8/33A61K8/36A61K8/365A61K8/46A61K8/97A61Q11/00A61K7/26A61K7/24
    • PROBLEM TO BE SOLVED: To obtain a composition for cleaning the inside of oral cavity, safe even on swallowing inadvertently, having less bitterness, capable of being used by especially highly aged persons and children easily without having incompatible feeling, and capable of obtaining a safe disinfecting effect on various bacteria existing in the oral cavity.
      SOLUTION: This composition for cleaning the inside of the oral cavity is provided by combining natural substances of a persimmon tannin extract and grape fruit seed extract, and capable of disinfecting causing bacteria aggravating the environment of the oral cavity such as those of caries, periodontal disease, bad breath, fur on the tongue, widely and effectively. The composition for cleaning the inside of the oral cavity different from conventional ones, is provided by incorporating a refreshing agent and/or a sweetening agent gentle to teeth together with the persimmon tannin extract and grape fruit seed extract and in a certain ratio of water. Further, it is preferable to incorporate at least 1 kind water soluble zinc compound selected from zinc chloride, zinc lactate, zinc sulfate, zinc acetate, zinc salicylate and zinc thiocyanate for improving the bad breath-deodorizing effect.
      COPYRIGHT: (C)2005,JPO&NCIPI
    • 要解决的问题:为了获得用于清洁口腔内部的组合物,即使在无意中吞咽,具有较少的苦味,能够容易地被特别高度老化的人和儿童使用而容易地安全地使用,而没有不相容的感觉,并且能够 对口腔中存在的各种细菌获得安全的消毒效果。 解决方案:用于清洁口腔内部的组合物通过将柿子单宁提取物的天然物质与葡萄果实种子提取物组合而提供,并且能够消毒引起细菌恶化口腔环境,例如龋齿 ,牙周病,口臭,舌头上的毛皮,广泛有效。 通过与柿子单宁提取物和葡萄果实种子提取物一起并且以一定比例的水混合清洁剂和/或与牙齿温和的甜味剂,来提供与常规口腔不同的用于清洁口腔内部的组合物。 此外,优选掺入至少1种选自氯化锌,乳酸锌,硫酸锌,醋酸锌,水杨酸锌和硫氰酸锌的水溶性锌化合物,以改善不良呼吸除臭效果。 版权所有(C)2005,JPO&NCIPI
    • 8. 发明专利
    • Bacterial plaque staining composition for evaluating dental caries activity
    • 用于评估牙科活动的细菌液体染色组合物
    • JP2008189575A
    • 2008-08-21
    • JP2007024354
    • 2007-02-02
    • Gc Corp株式会社ジーシー
    • LAURENCE J WALSHOTA RIYOUKONAGAO SEIKOSATO TAKUYA
    • A61K49/00
    • PROBLEM TO BE SOLVED: To obtain a bacterial plaque staining composition for evaluating dental caries activity, which approximately simultaneously carries out bacterial plaque staining and dental caries activity evaluation and evaluates dental caries activity relatively accurately even in thick bacterial plaque in comparison with a conventional bacterial plaque staining composition.
      SOLUTION: The bacterial plaque staining composition for evaluating dental caries activity comprises a blue pigment that is soluble in water and does not change a color tone at pH≤7, a red pigment that is soluble in water at pH>4.5 but not soluble in water and does not change a color tone at pH≤4.5 and a saccharide. The bacterial plaque staining composition comprises 1 pt.wt. of the total content of the blue pigment and the red pigment and 1-50 pts.wt. of saccharide content in the content ratio of the blue pigment to the red pigment of preferably 1:3-3:1.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:为了获得用于评估龋齿活性的细菌斑块染色组合物,其大致同时进行细菌斑块染色和龋齿活性评估,并且即使在厚细菌斑块中相对准确地评估龋齿活性,与 常规细菌斑块染色组成。 解决方案:用于评价龋齿活性的细菌斑块染色组合物包含可溶于水的蓝色颜料,并且不改变pH≤7时的色调,在pH> 4.5但不溶于水的红色颜料 溶于水,不改变pH≤4.5的色调和糖。 细菌斑块染色组合物包含1重量% 的蓝色颜料和红色颜料的总含量和1-50重量份。 的糖含量,蓝色颜料与红色颜料的含量比优选为1:3-3:1。 版权所有(C)2008,JPO&INPIT
    • 9. 发明专利
    • Caries-preventing composition
    • 预防组合物
    • JP2005145952A
    • 2005-06-09
    • JP2004260622
    • 2004-09-08
    • Gc Corp株式会社ジーシー
    • YAMANAKA KATSUYUKISATO TAKUYAYOSHII HIDEKAZUWATANABE YOSHIKO
    • A61K8/00A61K8/21A61K8/64A61K8/73A61Q11/00A61K7/16A61K7/18
    • PROBLEM TO BE SOLVED: To obtain a caries-preventing composition having an efficiently inhibiting effect on demineralization and accelerating re-calcification, and excellent in preservation stability for a long period.
      SOLUTION: This caries-preventing composition characterized by being used by applying on the teeth is constituted with (a) 1-30 wt.% casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP) and/or casein phosphopeptide-amorphous calcium fluoride phosphate complex (CPP-ACFP), (b) 0.01-10 wt.% sodium carboxymethylcellulose having 0.7-1.0 etherification degree, (c) 0.5-40 wt.% thickening agent, (e) 0.01-5.0 wt.% at least 1 kind of fluorine compound selected from sodium fluoride, tin fluoride and monofluoro sodium phosphate, which may be blended as necessary, and (d) the balance of water.
      COPYRIGHT: (C)2005,JPO&NCIPI
    • 待解决的问题:获得对脱矿质和加速再钙化有效抑制作用的长期保存稳定性优异的防龋剂组合物。 (a)1-30重量%的酪蛋白磷酸肽 - 无定形磷酸钙复合物(CPP-ACP)和/或酪蛋白磷酸肽 - 无定形的蛋白质 磷酸钙复合物(CPP-ACFP),(b)0.01-10重量%的具有0.7-1.0醚化度的羧甲基纤维素钠,(c)0.5-40重量%增稠剂,(e)0.01-5.0重量% 至少一种选自氟化钠,氟化锡和一氟磷酸钠的氟化合物,根据需要可以混合,和(d)余量的水。 版权所有(C)2005,JPO&NCIPI