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    • 1. 发明专利
    • Tooth-adhesive composition
    • 牙膏组合物
    • JP2011042609A
    • 2011-03-03
    • JP2009190937
    • 2009-08-20
    • Gc Corp株式会社ジーシー
    • YARIMIZU HIDEKITOKUI HIDEKINAGAO SEIKO
    • A61K6/00
    • A61K6/0023C08L33/10
    • PROBLEM TO BE SOLVED: To provide a tooth-adhesive composition which does not cause lowering of the preservation stability of the composition due to the reaction between a filler having X-ray imaging properties and an acid component in the composition and does not have the necessity for mixing and kneading of the composition separated in two or more packages in use unlike the conventional case.
      SOLUTION: The tooth-adhesive composition includes a (meth)acrylate compound (a) having an acid group, a filler (b) which is an aluminosilicate glass powder including Sr and/or Ba and/or Ca and having an Al
      2 O
      3 content of 15 wt.% or less in terms of oxides and does not substantially cause an ion reaction with the compound (a) of the (meth)acrylate compound having an acid group, and a photopolymerization catalyst (c), and these components (a), (b), and (c) coexist in one pack.
      COPYRIGHT: (C)2011,JPO&INPIT
    • 要解决的问题:提供一种牙膏组合物,其不会由于具有X射线成像性质的填料和组合物中的酸成分之间的反应而导致组合物的保存稳定性降低,并且不 需要与常规情况不同的是使用在两种或多种包装中分离的组合物进行混合和捏合。 解决方案:该粘合剂组合物包括具有酸基的(甲基)丙烯酸酯化合物(a),作为包含Sr和/或Ba和/或Ca的铝硅酸盐玻璃粉末的填料(b)和具有Al 氧化物含量为15重量%以下,实质上不与(甲基)丙烯酸酯化合物(a)的离子反应 具有酸基和光聚合催化剂(c),并且这些组分(a),(b)和(c)共存于一个包装中。 版权所有(C)2011,JPO&INPIT
    • 2. 发明专利
    • Composition for wetting oral cavity
    • 用于润湿口腔的组合物
    • JP2009235012A
    • 2009-10-15
    • JP2008085062
    • 2008-03-28
    • Gc Corp株式会社ジーシー
    • SATO TAKUYAKARIYA SHUJINAGAO SEIKOOTA RYOKO
    • A61K8/34A61K8/19A61K8/64A61K31/047A61K33/06A61K33/42A61P1/02A61Q11/00
    • PROBLEM TO BE SOLVED: To provide a composition for wetting an oral cavity, having a wetting effect on oral mucosa for a long period of time and simultaneously a preventive effect on dentin dental caries and acid erosion.
      SOLUTION: The composition for wetting an oral cavity comprises 2-10 wt.% of glycerol, 25-60 wt.% of a polyglycerol, 20-60 wt.% of water, 0.1-15 wt.% of a water-soluble polymer-based thickener, 0.05-5 wt.% of a water-soluble protein or water-soluble peptide, 0.01-5 wt.% of a water-soluble calcium salt and 0.03-3 wt.% of a water-soluble phosphate. Otherwise the composition for wetting the oral cavity comprises 2-10 wt.% of glycerol, 25-60 wt.% of a polyglycerol, 20-60 wt.% of water, 0.1-15 wt.% of a water-soluble polymer-based thickener and 0.05-10 wt.% of a hydrolyzed protein-amorphous calcium phosphate complex.
      COPYRIGHT: (C)2010,JPO&INPIT
    • 要解决的问题:提供一种用于润湿口腔的组合物,其对口腔粘膜长时间具有润湿作用,同时对牙本质龋齿和酸侵蚀具有预防作用。 解决方案:用于润湿口腔的组合物包含2-10重量%的甘油,25-60重量%的聚甘油,20-60重量%的水,0.1-15重量%的水 可溶性聚合物基增稠剂,0.05-5重量%的水溶性蛋白质或水溶性肽,0.01-5重量%的水溶性钙盐和0.03-3重量%的水溶性 磷酸盐。 否则用于润湿口腔的组合物包含2-10重量%的甘油,25-60重量%的聚甘油,20-60重量%的水,0.1-15重量%的水溶性聚合物 - 和0.05-10重量%的水解蛋白质 - 无定形磷酸钙复合物。 版权所有(C)2010,JPO&INPIT
    • 3. 发明专利
    • Composition for oral cavity
    • 口腔组成
    • JP2008063282A
    • 2008-03-21
    • JP2006243519
    • 2006-09-08
    • Gc Corp株式会社ジーシー
    • NAGAO SEIKOSAKAGUCHI YOSHIHIROKARIYA SHUJI
    • A61K8/19A61K8/73A61K31/728A61K33/24A61P1/02A61P39/06A61Q11/00
    • PROBLEM TO BE SOLVED: To provide a composition for oral cavity, consisting of an aqueous solution of platinum nano colloid and without agglomerating the platinum nano colloid during its preservation.
      SOLUTION: This composition for oral cavity contains the platinum nano colloid having 1 to 5 nm mean particle diameter, a hyaluronic acid salt and water. The composition can be used as a liquid dental paste material, mouth wash, tooth surface-applying agent, etc. These compositions can be blended with, for example a thickening agent, a surfactant, a sweetener, a preservative, various active ingredients, a coloring matter, an aromatizing agent or the like as necessary.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:提供一种口腔组合物,其由铂纳米胶体的水溶液组成,并且在其保存期间不使铂纳米胶体附聚。 解决方案:该口腔用组合物含有平均粒径为1〜5nm的铂纳米胶体,透明质酸盐和水。 该组合物可以用作液体牙膏材料,漱口剂,牙齿表面施用剂等。这些组合物可以与例如增稠剂,表面活性剂,甜味剂,防腐剂,各种活性成分, 着色剂,芳构化剂等。 版权所有(C)2008,JPO&INPIT
    • 4. 发明专利
    • Method for regulating quorum sensing of bacterium
    • 调节细菌感应度的方法
    • JP2008043209A
    • 2008-02-28
    • JP2006219118
    • 2006-08-11
    • Gc Corp株式会社ジーシー
    • SATO TAKUYANAGAO SEIKO
    • C12N1/20
    • PROBLEM TO BE SOLVED: To provide a method for regulating quorum sensing without a risk of reducing useful bacteria or producing resistant bacteria in an affected part.
      SOLUTION: The method for regulating the quorum sensing of bacteria comprises using a platinum nano-colloid. Furthermore, the platinum nano-colloid is used by bringing the platinum nano-colloid together with a solvent forming and maintaining the colloid, preferably polyvinylpyrrolidone, polyacrylic acid and a polyacrylate, citric acid and a citrate into contact with the affected part or a culturing environment for the bacteria.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:提供一种用于调节群体感测的方法,而不会在受影响的部分中降低有用细菌或产生耐药细菌的风险。

      解决方案:调节细菌群体感应的方法包括使用铂纳米胶体。 此外,通过使铂纳米胶体与溶剂形成并保持胶体(优选聚乙烯吡咯烷酮,聚丙烯酸和聚丙烯酸酯,柠檬酸和柠檬酸盐)与受影响的部分或培养环境接触来使用铂纳米胶体 为细菌。 版权所有(C)2008,JPO&INPIT

    • 5. 发明专利
    • Antimicrobial composition for oral cavity use
    • 用于口腔使用的抗微生物组合物
    • JP2011051941A
    • 2011-03-17
    • JP2009203234
    • 2009-09-03
    • Gc Corp株式会社ジーシー
    • YARIMIZU HIDEKIKATO KATSUTONAGAO SEIKO
    • A61K6/00A61K6/083A61K31/155A61P1/02
    • PROBLEM TO BE SOLVED: To provide an antimicrobial composition for oral cavity use, having an antimicrobial effect not only in a dental prosthesis but also in a wide area in the oral cavity and high curability and forming a film for a long period of time.
      SOLUTION: The antimicrobial composition for oral cavity use includes 15-70 wt.% of a monofunctional (meth)acrylate compound not containing an acid group, 15-70 wt.% of a polyfunctional (meth)acrylate compound not containing an acid group, 1-20 wt.% of a (meth)acrylate compound containing an acid group, 0.01-10 wt.% of a polymerization initiator and 0.001-10 wt.% of chlorhexidine and/or its compound.
      COPYRIGHT: (C)2011,JPO&INPIT
    • 要解决的问题:提供一种口腔用抗微生物组合物,其不仅在牙科假体中具有抗菌作用,而且在口腔的广泛区域中具有抗菌作用,并且具有高的固化性,并且长时间形成膜 时间。 口腔用抗微生物组合物包括15-70重量%的不含酸基的单官能(甲基)丙烯酸酯化合物,15-70重量%的不含有(甲基)丙烯酸酯的多官能(甲基)丙烯酸酯化合物 酸基团,1-20重量%的含酸基的(甲基)丙烯酸酯化合物,0.01-10重量%的聚合引发剂和0.001-10重量%的氯己定和/或其化合物。 版权所有(C)2011,JPO&INPIT
    • 7. 发明专利
    • Bacterial plaque staining composition for evaluating dental caries activity
    • 用于评估牙科活动的细菌液体染色组合物
    • JP2008189575A
    • 2008-08-21
    • JP2007024354
    • 2007-02-02
    • Gc Corp株式会社ジーシー
    • LAURENCE J WALSHOTA RIYOUKONAGAO SEIKOSATO TAKUYA
    • A61K49/00
    • PROBLEM TO BE SOLVED: To obtain a bacterial plaque staining composition for evaluating dental caries activity, which approximately simultaneously carries out bacterial plaque staining and dental caries activity evaluation and evaluates dental caries activity relatively accurately even in thick bacterial plaque in comparison with a conventional bacterial plaque staining composition.
      SOLUTION: The bacterial plaque staining composition for evaluating dental caries activity comprises a blue pigment that is soluble in water and does not change a color tone at pH≤7, a red pigment that is soluble in water at pH>4.5 but not soluble in water and does not change a color tone at pH≤4.5 and a saccharide. The bacterial plaque staining composition comprises 1 pt.wt. of the total content of the blue pigment and the red pigment and 1-50 pts.wt. of saccharide content in the content ratio of the blue pigment to the red pigment of preferably 1:3-3:1.
      COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:为了获得用于评估龋齿活性的细菌斑块染色组合物,其大致同时进行细菌斑块染色和龋齿活性评估,并且即使在厚细菌斑块中相对准确地评估龋齿活性,与 常规细菌斑块染色组成。 解决方案:用于评价龋齿活性的细菌斑块染色组合物包含可溶于水的蓝色颜料,并且不改变pH≤7时的色调,在pH> 4.5但不溶于水的红色颜料 溶于水,不改变pH≤4.5的色调和糖。 细菌斑块染色组合物包含1重量% 的蓝色颜料和红色颜料的总含量和1-50重量份。 的糖含量,蓝色颜料与红色颜料的含量比优选为1:3-3:1。 版权所有(C)2008,JPO&INPIT