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1. 发明申请

US20120135108A1 Grain Compositions Containing Pre-Biotic Isomal To-Oligosaccharides And Methods Of Making And Using Same 有权
标题翻译：含有预生物异构异构寡糖的谷物组合物及其制备和使用方法
公开(公告)号：US20120135108A1
公开(公告)日：2012-05-31
申请号：US13172744
申请日：2011-06-29
申请人： Gang Duan , Feng Li , Jayarama K. Shetty , Julius Vadakoot , Sridevi Vadakoot
发明人： Gang Duan , Feng Li , Jayarama K. Shetty , Julius Vadakoot , Sridevi Vadakoot
IPC分类号： A23L1/186 , A23L1/09
CPC分类号： A21D2/181 , A23L29/35 , C07H3/06 , C12C5/00 , C12P19/04 , C12P19/14 , C12P19/18 , C12P19/22
摘要： Methods for the production of substrate, tuber, and grain compositions containing isomalto-oligosaccharides are described. The methods comprise (a) contacting a substrate, tuber or grain containing ungelatinized starch with a maltogenic enzyme and a starch liquefying enzyme to produce maltose; (b) contacting said maltose with a transglucosidic enzyme, wherein said steps (a) and step (b) occur at a temperature less than or at a starch gelatinization temperature; and (c) obtaining a substrate, grain or tuber composition having an enzymatically produced isomalto-oligosaccharide, wherein the oligosaccharide is derived from the grain. The maltogenic enzyme can be either exogenous or endogenous to the grain. The contacting steps can be sequential or concurrent. The present invention also describes flour, oral rehydrating solutions, beer adjuncts, food, feed, beverage additives incorporating the grain compositions made as described.
摘要翻译：描述了生产含有异麦芽低聚糖的底物，块茎和谷物组合物的方法。所述方法包括（a）使含有未凝胶化淀粉的底物，块茎或谷粒与麦芽糖酶和淀粉液化酶接触以产生麦芽糖; （b）使所述麦芽糖与转葡糖苷酶接触，其中所述步骤（a）和步骤（b）在低于淀粉糊化温度或淀粉糊化温度的温度下进行; 和（c）获得具有酶促产生的异麦芽低聚糖的底物，谷物或块茎组合物，其中寡糖衍生自谷物。麦芽糖酶可以是外源的或内源的谷物。接触步骤可以是顺序的或并发的。本发明还描述了包含如上所述制备的谷物组合物的面粉，口服再水合溶液，啤酒助剂，食品，饲料，饮料添加剂。

2. 发明授权

US07638151B2 Grain compositions containing pre-biotic isomalto-oligosaccharides and methods of making and using same 有权
标题翻译：含有预生物异麦芽低聚糖的颗粒组合物及其制备和使用方法
公开(公告)号：US07638151B2
公开(公告)日：2009-12-29
申请号：US10798549
申请日：2004-03-10
申请人： Gang Duan , Feng Li , Jayarama K. Shetty , Julius Vadakoot , Sridevi Vadakoot, legal representative
发明人： Gang Duan , Feng Li , Jayarama K. Shetty , Julius Vadakoot
IPC分类号： A21D2/00 , C12P19/14
CPC分类号： A21D2/181 , A23L29/35 , C07H3/06 , C12C5/00 , C12P19/04 , C12P19/14 , C12P19/18 , C12P19/22
摘要： Methods for the production of substrate, tuber, and grain compositions containing isomalto-oligosaccharides are described. The methods comprise (a) contacting a substrate, tuber or grain containing ungelatinized starch with a maltogenic enzyme and a starch liquefying enzyme to produce maltose; (b) contacting said maltose with a transglucosidic enzyme, wherein said steps (a) and step (b) occur at a temperature less than or at a starch gelatinization temperature; and (c) obtaining a substrate, grain or tuber composition having an enzymatically produced isomalto-oligosaccharide, wherein the oligosaccharide is derived from the grain. The maltogenic enzyme can be either exogenous or endogenous to the grain. The contacting steps can be sequential or concurrent. The present invention also describes flour, oral rehydrating solutions, beer adjuncts, food, feed, beverage additives incorporating the grain compositions made as described.
摘要翻译：描述了生产含有异麦芽低聚糖的底物，块茎和谷物组合物的方法。所述方法包括（a）使含有未凝胶化淀粉的底物，块茎或谷粒与麦芽糖酶和淀粉液化酶接触以产生麦芽糖; （b）使所述麦芽糖与转葡糖苷酶接触，其中所述步骤（a）和步骤（b）在低于淀粉糊化温度或淀粉糊化温度的温度下进行; 和（c）获得具有酶促产生的异麦芽低聚糖的底物，谷物或块茎组合物，其中寡糖衍生自谷物。麦芽糖酶可以是外源的或内源的谷物。接触步骤可以是顺序的或并发的。本发明还描述了包含如上所述制备的谷物组合物的面粉，口服再水合溶液，啤酒助剂，食品，饲料，饮料添加剂。

3. 发明授权

US07993689B2 Grain compositions containing pre-biotic isomalto-oligosaccharides and methods of making and using same 有权
标题翻译：含有预生物异麦芽低聚糖的颗粒组合物及其制备和使用方法
公开(公告)号：US07993689B2
公开(公告)日：2011-08-09
申请号：US12616595
申请日：2009-11-11
申请人： Gang Duan , Fengi Li , Jayarama K. Shetty , Julius Vadakoot , Sridevi Vadakoot, legal representative
发明人： Gang Duan , Fengi Li , Jayarama K. Shetty , Julius Vadakoot
IPC分类号： A21D2/00 , C12P19/14
CPC分类号： A21D2/181 , A23L29/35 , C07H3/06 , C12C5/00 , C12P19/04 , C12P19/14 , C12P19/18 , C12P19/22
摘要： Methods for the production of substrate, tuber, and grain compositions containing isomalto-oligosaccharides are described. The methods comprise (a) contacting a substrate, tuber or grain containing ungelatinized starch with a maltogenic enzyme and a starch liquefying enzyme to produce maltose; (b) contacting the maltose with a transglucosidic enzyme, wherein the steps (a) and (b) occur at a temperature less than or at a starch gelatinization temperature; and (c) obtaining a substrate, grain or tuber composition having an enzymatically produced isomalto-oligosaccharide, wherein the oligosaccharide is derived from the grain. The maltogenic enzyme can be either exogenous or endogenous to the grain. The contacting steps can be sequential or concurrent. The present invention also describes flour, oral rehydrating solutions, beer adjuncts, food, feed, beverage additives incorporating the grain compositions made as described.
摘要翻译：描述了生产含有异麦芽低聚糖的底物，块茎和谷物组合物的方法。所述方法包括（a）使含有未凝胶化淀粉的底物，块茎或谷粒与麦芽糖酶和淀粉液化酶接触以产生麦芽糖; （b）使麦芽糖与转葡糖苷酶接触，其中步骤（a）和（b）在低于淀粉糊化温度或淀粉糊化温度的温度下进行; 和（c）获得具有酶促产生的异麦芽低聚糖的底物，谷物或块茎组合物，其中寡糖衍生自谷物。麦芽糖酶可以是外源的或内源的谷物。接触步骤可以是顺序的或并发的。本发明还描述了包含如上所述制备的谷物组合物的面粉，口服再水合溶液，啤酒助剂，食品，饲料，饮料添加剂。

4. 发明授权

US08715755B2 Grain compositions containing pre-biotic isomalto-oligosaccharides and methods of making and using same 有权
标题翻译：含有预生物异麦芽低聚糖的颗粒组合物及其制备和使用方法
公开(公告)号：US08715755B2
公开(公告)日：2014-05-06
申请号：US13172744
申请日：2011-06-29
申请人： Gang Duan , Feng Li , Jayarama K. Shetty , Sridevi Vadakoot
发明人： Gang Duan , Feng Li , Jayarama K. Shetty , Julius Vadakoot
IPC分类号： A23L1/10 , A23L1/186
CPC分类号： A21D2/181 , A23L29/35 , C07H3/06 , C12C5/00 , C12P19/04 , C12P19/14 , C12P19/18 , C12P19/22
摘要： Methods for the production of substrate, tuber, and grain compositions containing isomalto-oligosaccharides are described. The methods comprise (a) contacting a substrate, tuber or grain containing ungelatinized starch with a maltogenic enzyme and a starch liquefying enzyme to produce maltose; (b) contacting the maltose with a transglucosidic enzyme, wherein the steps (a) and (b) occur at a temperature less than or at a starch gelatinization temperature; and (c) obtaining a substrate, grain or tuber composition having an enzymatically produced isomalto-oligosaccharide, wherein the oligosaccharide is derived from the grain. The maltogenic enzyme can be either exogenous or endogenous to the grain. The contacting steps can be sequential or concurrent. The present invention also describes flour, oral rehydrating solutions, beer adjuncts, food, feed, beverage additives incorporating the grain compositions made as described.
摘要翻译：描述了生产含有异麦芽低聚糖的底物，块茎和谷物组合物的方法。所述方法包括（a）使含有未凝胶化淀粉的底物，块茎或谷粒与麦芽糖酶和淀粉液化酶接触以产生麦芽糖; （b）使麦芽糖与转葡糖苷酶接触，其中步骤（a）和（b）在低于淀粉糊化温度或淀粉糊化温度的温度下进行; 和（c）获得具有酶促产生的异麦芽低聚糖的底物，谷物或块茎组合物，其中寡糖衍生自谷物。麦芽糖酶可以是外源的或内源的谷物。接触步骤可以是顺序的或并发的。本发明还描述了包含如上所述制备的谷物组合物的面粉，口服再水合溶液，啤酒助剂，食品，饲料，饮料添加剂。

5. 发明申请

US20050031734A1 Grain compositions containing pre-biotic isomalto-oligosaccharides and methods of making and using same 有权
标题翻译：含有预生物异麦芽低聚糖的颗粒组合物及其制备和使用方法
公开(公告)号：US20050031734A1
公开(公告)日：2005-02-10
申请号：US10798549
申请日：2004-03-10
申请人： Gang Duan , Feng Li , Jayarama Shetty , Julius Vadakoot , Sridevi Vadakoot
发明人： Gang Duan , Feng Li , Jayarama Shetty , Julius Vadakoot , Sridevi Vadakoot
IPC分类号： A21D2/18 , A23L1/09 , C07H3/06 , C12C5/00 , C12P19/04 , C12P19/14 , C12P19/18 , C12P19/22 , A21D2/00 , A21D8/02
CPC分类号： A21D2/181 , A23L29/35 , C07H3/06 , C12C5/00 , C12P19/04 , C12P19/14 , C12P19/18 , C12P19/22
摘要： Methods for the production of substrate, tuber, and grain compositions containing isomalto-oligosaccharides are described. The methods comprise (a) contacting a substrate, tuber or grain containing ungelatinized starch with a maltogenic enzyme and a starch liquefying enzyme to produce maltose; (b) contacting said maltose with a transglucosidic enzyme, wherein said steps (a) and step (b) occur at a temperature less than or at a starch gelatinization temperature; and (c) obtaining a substrate, grain or tuber composition having an enzymatically produced isomalto-oligosaccharide, wherein the oligosaccharide is derived from the grain. The maltogenic enzyme can be either exogenous or endogenous to the grain. The contacting steps can be sequential or concurrent. The present invention also describes flour, oral rehydrating solutions, beer adjuncts, food, feed, beverage additives incorporating the grain compositions made as described.
摘要翻译：描述了生产含有异麦芽低聚糖的底物，块茎和谷物组合物的方法。所述方法包括（a）使含有未凝胶化淀粉的底物，块茎或谷粒与麦芽糖酶和淀粉液化酶接触以产生麦芽糖; （b）使所述麦芽糖与转葡糖苷酶接触，其中所述步骤（a）和步骤（b）在低于淀粉糊化温度或淀粉糊化温度的温度下进行; 和（c）获得具有酶促产生的异麦芽低聚糖的底物，谷物或块茎组合物，其中寡糖衍生自谷物。麦芽糖酶可以是外源的或内源的谷物。接触步骤可以是顺序的或并发的。本发明还描述了包含如上所述制备的谷物组合物的面粉，口服再水合溶液，啤酒助剂，食品，饲料，饮料添加剂。

6. 发明授权

US08916369B2 Trichoderma reesei α-amylase is a maltogenic enzyme 有权
标题翻译：里氏木霉α-淀粉酶是一种麦芽糖酶
公开(公告)号：US08916369B2
公开(公告)日：2014-12-23
申请号：US12531970
申请日：2008-03-12
申请人： Gang Duan , Kathy Qian , Martijn Scheffers , Jayarama K. Shetty , Pieter Van Solingen
发明人： Gang Duan , Kathy Qian , Martijn Scheffers , Jayarama K. Shetty , Pieter Van Solingen
IPC分类号： C12P21/06 , C12N9/00 , C12N9/28 , C12N1/20 , C12N15/00 , C07H21/04 , C12N9/30
CPC分类号： C12N9/242
摘要： A maltogenic a-amylase from Trichoderma reesei (TrAA) and variants thereof are useful in the production of high-maltose syrups from liquefied starch. Particularly high maltose concentrations are achieved when TrAA is used in the presence of a pullulanase. Expression hosts and encoding nucleic acids useful for producing TrAA and its variants also are provided.
摘要翻译：来自里氏木霉（TrAA）的麦芽糖α-淀粉酶及其变体可用于从液化淀粉生产高麦芽糖浆。当在存在支链淀粉酶的情况下使用TrAA时，可实现特别高的麦芽糖浓度。还提供了用于产生TrAA及其变体的表达宿主和编码核酸。

7. 发明授权

US08075694B2 Acid fungal protease in fermentation of insoluble starch substrates 有权
标题翻译：酸性真菌蛋白酶在不溶性淀粉基质发酵中的应用
公开(公告)号：US08075694B2
公开(公告)日：2011-12-13
申请号：US12485767
申请日：2009-06-16
申请人： Gang Duan , Nigel Dunn-Coleman , Oreste Lantero , Craig E. Pilgrim , Jayarama K. Shetty
发明人： Gang Duan , Nigel Dunn-Coleman , Oreste Lantero , Craig E. Pilgrim , Jayarama K. Shetty
IPC分类号： C08B37/00 , C12C1/00
CPC分类号： C12N9/58 , A23L13/424 , A23L33/18 , C12N9/48 , C12P7/06 , C12P7/10 , C12P19/02 , Y02E50/16 , Y02E50/17
摘要： The invention is directed to methods of producing ethanol and decreasing residual starch production in a no cook fermentation comprising contacting granular starch containing substrates with a granular starch hydrolyzing enzyme, a protease, and a fermenting microorganism under suitable fermentation conditions at a temperature below the starch gelatinization temperature of the starch substrate to produce ethanol, wherein the ethanol production is increased and the amount of residual starch is decreased compared to a substantially similar method conducted without the protease.
摘要翻译：本发明涉及生产乙醇的方法，并且在无烹饪发酵中减少残余淀粉的产生，包括在合适的发酵条件下，在低于淀粉糊化温度的温度下，使含有颗粒淀粉的底物与颗粒状淀粉水解酶，蛋白酶和发酵微生物接触淀粉底物的温度以产生乙醇，其中乙醇生产增加，并且残余淀粉的量与基本上相似的不含蛋白酶的方法相比降低。

8. 发明申请

US20130203140A1 PRODUCTION OF ISOPRENOIDS UNDER NEUTRAL pH CONDITIONS 有权
标题翻译：在中性pH条件下生产异烟肼
公开(公告)号：US20130203140A1
公开(公告)日：2013-08-08
申请号：US13566923
申请日：2012-08-03
申请人： Martien H. BERGSMA , Anthony R. Calabria , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
发明人： Martien H. BERGSMA , Anthony R. Calabria , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
IPC分类号： C12P5/00
CPC分类号： C12P5/007 , C12N9/1085 , C12N9/2428 , C12Y205/0101 , C12Y302/01003
摘要： Embodiments of the present disclosure relate to a process for producing isoprenoid precursor molecules and/or isoprenoids from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process.
摘要翻译：本公开的实施方案涉及通过糖化和/或发酵从淀粉底物生产类异戊二烯前体分子和/或类异戊二烯的方法。糖化在pH为5.0至8.0的范围内由葡糖淀粉酶有效地催化。在6.0或更高的pH下，葡糖淀粉酶相对于其最大活性具有至少50％的活性。糖化和发酵可以作为同时糖化和发酵（SSF）方法进行。

9. 发明申请

US20130142903A1 FOOD PRODUCT COMPRISING A LOW TEMPERATURE RICE PROTEIN CONCENTRATE 审中-公开
标题翻译：包含低温米饭蛋白浓度的食品
公开(公告)号：US20130142903A1
公开(公告)日：2013-06-06
申请号：US13817132
申请日：2011-08-19
申请人： Gang Duan , Kathleen Burns Jacobsen , Jayarama K. Shetty , Qian Ying , Troy Wilson
发明人： Gang Duan , Kathleen Burns Jacobsen , Jayarama K. Shetty , Qian Ying , Troy Wilson
IPC分类号： A23J3/34
CPC分类号： A23J3/346 , A23G1/54 , A23G3/54 , A23J1/125 , A23J3/14 , A23K20/147 , A23L33/185 , A23V2002/00 , C12Y302/01001 , C12Y302/01003 , A23V2250/548
摘要： Rice protein concentrates prepared at low temperature exhibit improved functionality and beneficial physiological benefits, including lowered cholesterol and enhanced lactic acid dehydrogenase activity, without an increase in blood urea nitrogen. The rice protein concentration could be made into a wet dough with comparatively less water than a soy protein concentrate. Use of the rice protein concentrate thus improved processing steps in the formulation of a food article containing the concentrate. The food product advantageously shows an extending shelf life and improved palatable texture.
摘要翻译：在低温下制备的大米蛋白浓缩物显示改善的功能和有益的生理益处，包括降低的胆固醇和提高的乳酸脱氢酶活性，而不增加血液尿素氮。大米蛋白质浓度可以制成湿面团，水分比大豆蛋白浓缩物少。大米蛋白浓缩物的使用从而改善了含有浓缩物的食品制剂的加工步骤。食品有利地显示出延长的保质期和改善的可口的质感。

10. 发明申请

US20120034659A1 NEUTRAL pH SACCHARIFICATION AND FERMENTATION 审中-公开
标题翻译：中性pH浓度和发酵
公开(公告)号：US20120034659A1
公开(公告)日：2012-02-09
申请号：US13204561
申请日：2011-08-05
申请人： Martien H. Bergsma , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
发明人： Martien H. Bergsma , Gopal K. Chotani , William A. Cuevas , Gang Duan , Sung Ho Lee , Ying Qian , Vivek Sharma , Jayarama K. Shetty , Bruce A. Strohm , Paula Johanna Maria Teunissen , Hongxian Xu
IPC分类号： C12P19/20 , C12P7/04 , C12P7/16 , C12P7/56 , C12P7/46 , C12P7/18 , C12P13/04 , C12P7/14 , C12P13/14
CPC分类号： C12P7/06 , C12P7/04 , C12P7/14 , C12P7/16 , C12P7/18 , C12P7/46 , C12P7/56 , C12P13/04 , C12P13/14 , C12P19/20 , Y02E50/10 , Y02E50/17
摘要： Embodiments of the present disclosure relate to a process for producing downstream products, such as fermentable sugars and end products, from a starch substrate by saccharification and/or fermentation. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.0 to 8.0. At a pH of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. The saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (SSF) process.
摘要翻译：本公开的实施方案涉及通过糖化和/或发酵从淀粉底物生产下游产物如可发酵糖和终产物的方法。糖化在pH为5.0至8.0的范围内由葡糖淀粉酶有效地催化。在6.0或更高的pH下，葡糖淀粉酶相对于其最大活性具有至少50％的活性。糖化和发酵可以作为同时糖化和发酵（SSF）方法进行。

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