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1. 发明申请

WO2007068900A3 MEDICAMENT DISPENSER 审中-公开
标题翻译：药物分配器
公开(公告)号：WO2007068900A3
公开(公告)日：2007-07-26
申请号：PCT/GB2006004623
申请日：2006-12-11
申请人： GLAXO GROUP LTD , ANDERSON GREGOR JOHN MCLENNAN , DAVIES MICHAEL BIRSHA , HAILEY MARK ANDREW , PALMER MARK GREGORY , WALKER RICHARD IAN
发明人： ANDERSON GREGOR JOHN MCLENNAN , DAVIES MICHAEL BIRSHA , HAILEY MARK ANDREW , PALMER MARK GREGORY , WALKER RICHARD IAN
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0026 , A61M15/0043 , A61M15/0051 , A61M15/0055 , A61M15/007 , A61M15/0075 , A61M2202/064 , A61M2205/12
摘要： There is provided a medicament dispenser device for the delivery of medicament powder from an open blister pocket (404a,b) of at least one blister pack (400a,b). The dispenser device comprises a housing (420) having an air inlet (470); enclosed by the housing, a dispensing mechanism (440, 448a,b) for the dispensing of medicament powder from an open blister pocket; and associated with the dispensing mechanism and in communication with the air inlet, a manifold (450). The manifold comprises a body, the body defining a chimney (452) having a chimney inlet (453) and a chimney exit (454a,b) for directing airflow (483) from said chimney inlet to said chimney exit; the body further defining a chamber (460) having a chamber inlet (473a,b) and a chamber exit (474), wherein the chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof. In use, the airflow is drawn into the chimney of the manifold solely through the air inlet provided to the housing.
摘要翻译：提供了一种用于从至少一个泡罩包装（400a，b）的开口泡罩袋（404a，b）输送药物粉末的药物分配器装置。分配器装置包括具有空气入口（470）的壳体（420）; 由外壳封闭的分配机构（440,448a，b），用于从开口泡罩袋中分配药物粉末; 并且与分配机构相关联并且与空气入口连通，歧管（450）。所述歧管包括主体，所述主体限定具有烟囱入口（453）和烟囱出口（454a，b）的烟囱（452），烟囱出口用于将气流（483）从所述烟囱入口引导至所述烟囱出口; 所述主体进一步限定具有腔室入口（473a，b）和腔室出口（474）的腔室（460），其中所述烟囱出口和所述腔室入口彼此并排设置，使得当所述开口泡罩袋所述泡罩包装定位在其附近，所述气流可以从烟囱出口通过敞开的泡罩袋引导至腔室入口，以夹带所述药物粉末并使其能够运输。在使用中，气流仅通过提供给壳体的进气口被吸入歧管的烟囱中。

2. 发明申请

WO0056632A2 VALVE 审中-公开
标题翻译：阀
公开(公告)号：WO0056632A2
公开(公告)日：2000-09-28
申请号：PCT/EP0001444
申请日：2000-02-23
申请人： GLAXO GROUP LTD , ANDERSON GREGOR JOHN MCLENNAN , HAILEY MARK ANDREW , RUSSELL DAVID JOSEPH , GODFREY JAMES WILLIAM
发明人： ANDERSON GREGOR JOHN MCLENNAN , HAILEY MARK ANDREW , RUSSELL DAVID JOSEPH , GODFREY JAMES WILLIAM
IPC分类号： B65D83/44 , B05B9/04 , B65D83/14 , B65D83/00
CPC分类号： B65D83/48 , B65D83/54
摘要： There is provided a valve for an aerosol container. The valve comprises a valve body (1), within the valve body (1), a sealing ring (112) and receivable by the sealing ring (112), a valve stem (108) having a dispensing passage (10, 11). The valve stem (108) is slidably movable within the sealing ring (112) from a valve-closed position to a valve-open position in which the interior of the valve body is in communication with the dispensing passage (10, 11). The sealing ring (112) is shaped such as to reduce the contact area between the sealing ring (112) and the valve stem (108). Preferably, the valve is a metering valve.
摘要翻译：提供了一种用于气溶胶容器的阀。所述阀包括在所述阀体（1）内的阀体（1），密封环（112）并且可由所述密封环（112）接收，阀杆（108）具有分配通道（10,11）。阀杆（108）可在密封环（112）内从阀关闭位置可滑动地移动到阀打开位置，在该位置阀体的内部与分配通道（10,11）连通。密封环（112）成形为减小密封环（112）和阀杆（108）之间的接触面积。优选地，阀是计量阀。

3. 发明申请

WO0164273A3 METERED DOSE INHALER 审中-公开
标题翻译：计量剂量吸入器
公开(公告)号：WO0164273A3
公开(公告)日：2002-03-28
申请号：PCT/EP0102212
申请日：2001-02-28
申请人： GLAXO GROUP LTD , HAILEY MARK ANDREW
发明人： HAILEY MARK ANDREW
IPC分类号： A61M15/00 , A61K9/00 , A61M11/00 , A61M15/08 , B05B9/04 , B65D83/14
CPC分类号： A61K9/008 , A61M15/009
摘要： There is provided according to the invention a metered dose inhaler comprising an interfacial surface having the following properties: i) a contact angle of greater than 70 degrees; and ii) a conductivity of greater than 2.4 mS. There are also provided processes for its preparation and its use in therapy.
摘要翻译：根据本发明提供了一种计量剂量吸入器，其包括具有以下特性的界面：i）大于70度的接触角; 和ii）大于2.4mS的电导率。还提供了其制备方法及其在治疗中的应用。

4. 发明申请

WO0164274A3 METERED DOSE INHALER 审中-公开
标题翻译：计量剂量吸入器
公开(公告)号：WO0164274A3
公开(公告)日：2002-02-07
申请号：PCT/EP0102213
申请日：2001-02-28
申请人： GLAXO GROUP LTD , HAILEY MARK ANDREW
发明人： HAILEY MARK ANDREW
IPC分类号： A61K9/00 , A61M15/00 , A61K9/16 , A61M35/00 , B05D5/08 , B65D83/14 , C07F9/09 , C08F8/18 , C08G65/00 , C08G65/32 , C08G65/327 , C08G65/336 , C08K3/00 , C08L27/16 , C09D127/12 , C09D171/00 , G01N1/24
CPC分类号： A61K9/008 , A61M15/009
摘要： There is provided according to the invention a metered dose inhaler comprising an interfacial surface having a linear, non-cross-linked polymeric compound disposed thereon. There are also provided processes for its preparation and its use in therapy.
摘要翻译：根据本发明提供了一种定量吸入器，其包括其上设置有线性非交联聚合物的界面。还提供了其制备方法及其在治疗中的应用。

5. 发明申请

WO0164524A3 METERED DOSE INHALER 审中-公开
标题翻译：计量剂量吸入器
公开(公告)号：WO0164524A3
公开(公告)日：2002-03-28
申请号：PCT/EP0102214
申请日：2001-02-28
申请人： GLAXO GROUP LTD , HAILEY MARK ANDREW
发明人： HAILEY MARK ANDREW
IPC分类号： A61M11/00 , A61K9/00 , A61M15/00 , C08G65/00 , B65D83/14
CPC分类号： C08G65/007 , A61K9/008 , A61M15/0065
摘要： There is provided according to the invention a metered dose inhaler for dispensing a medicament, comprising an interfacial surface having a fluorocarbon polymeric compound dispensed thereon, such that deposition of the medicament on the metered dose inhaler is reduced by between 30 % and 80 %. There are also provided for its preparation and its use in therapy.
摘要翻译：根据本发明提供了一种用于分配药物的计量剂量吸入器，其包括其上分配有氟碳聚合物的界面，使得计量剂量吸入器上的药物沉积减少30％至80％。还提供其制备及其在治疗中的应用。

6. 发明专利

NZ569036A Medicament dispenser for inhalation of powder with only part of the airflow drawn in directed to the blister pocket 未知
公开(公告)号：NZ569036A
公开(公告)日：2011-08-26
申请号：NZ56903606
申请日：2006-12-11
申请人： GLAXO GROUP LTD
发明人： DAVIES MICHAEL BIRSHA , HAILEY MARK ANDREW , PALMER MARK GREGORY , WALKER RICHARD IAN , ANDERSON GREGOR JOHN MCLENNAN
IPC分类号： A61M15/00
摘要： There is provided a medicament dispenser device for the delivery of medicament powder from an open blister pocket of at least one blister pack. The dispenser device comprises a housing having an air inlet (470); enclosed by the housing, a dispensing mechanism for the dispensing of medicament powder from an open blister pocket; and associated with the dispensing mechanism and in communication with the air inlet, a manifold (450). The manifold comprises a body, the body defining a chimney (452) having a chimney inlet (453) and a chimney exit (454b) for directing airflow (483) from said chimney inlet to said chimney exit; the body further defining a chamber having a chamber inlet (473b) and a chamber exit (474), wherein the chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof. In use, the airflow is drawn into the chimney of the manifold solely through the air inlet provided to the housing.

7. 发明专利

ES2209956T3 未知
公开(公告)号：ES2209956T3
公开(公告)日：2004-07-01
申请号：ES00956311
申请日：2000-07-27
申请人： GLAXO GROUP LTD
发明人： GODFREY JAMES WILLIAM , HAILEY MARK ANDREW , KOWALSKI JULIAN ZBIGNIEW
IPC分类号： A61M15/00 , B41M5/26 , B44C1/00 , G01B3/12

8. 发明专利

AU3656200A Valve 未知
公开(公告)号：AU3656200A
公开(公告)日：2000-10-09
申请号：AU3656200
申请日：2000-02-23
申请人： GLAXO GROUP LTD
发明人： ANDERSON GREGOR JOHN MCLENNAN , HAILEY MARK ANDREW , RUSSELL DAVID JOSEPH , GODFREY JAMES WILLIAM
IPC分类号： B65D83/44 , B05B9/04 , B65D83/14 , B65D83/00

9. 发明专利

ES2897661T3 Dispensador de medicamentos 未知
公开(公告)号：ES2897661T3
公开(公告)日：2022-03-02
申请号：ES06820486
申请日：2006-12-11
申请人： GLAXO GROUP LTD
发明人： ANDERSON GREGOR JOHN MCLENNAN , DAVIES MICHAEL BIRSHA , HAILEY MARK ANDREW , PALMER MARK GREGORY , WALKER RICHARD IAN
IPC分类号： A61M15/00
摘要： Un dispositivo dispensador de medicamentos adecuado para el suministro de medicamentos en polvo desde un bolsillo de blíster abierto de al menos un envase tipo blíster, comprendiendo el dispositivo dispensador (a) un alojamiento; (b) proporcionándose en dicho alojamiento, una entrada de aire; (c) encerrado por dicho alojamiento, un mecanismo de dispensación para dispensar medicamento en polvo desde un bolsillo de blíster abierto de al menos un envase tipo blíster que se puede recibir por el mismo; y (d) asociado con dicho mecanismo de dispensación y en comunicación con dicha entrada de aire, un colector que comprende (i) un cuerpo, (ii) definiendo dicho cuerpo una chimenea que tiene una entrada de chimenea y una salida de chimenea para dirigir el flujo de aire de dicha entrada de chimenea a dicha salida de chimenea; (iii) definiendo además el cuerpo una cámara que tiene una entrada de cámara y una salida de cámara, (iv) en donde la salida de chimenea y dicha entrada de cámara se encuentran una al lado de la otra de tal forma que cuando dicho bolsillo de blíster abierta de dicho envase tipo blíster se coloca adyacente a la misma, dicho flujo de aire se dirigirá de la salida de chimenea a la entrada de cámara a través del bolsillo de blíster abierto para arrastrar dicho medicamento en polvo y permitir su transporte en el flujo de aire de la entrada de cámara a la salida de dicha salida de cámara, caracterizado porque, durante el uso inhalado del dispositivo dispensador por parte de un paciente, el flujo de aire se introduce en la chimenea del colector únicamente a través de la entrada de aire proporcionada en el alojamiento, en donde la entrada de aire proporciona el único punto de entrada para que el aire fluya hacia el alojamiento durante el uso inhalado del dispositivo dispensador por parte de un paciente, solo una parte del flujo de aire extraído a través de la entrada de aire y hacia la chimenea del colector se dirige a través de la salida de chimenea hacia el bolsillo de blíster abierto, y se proporcionan uno o más orificios de purga (480) entre la chimenea y la cámara de tal forma que una parte del flujo de aire (el flujo de aire de purga) se dirigirá hacia la cámara a través de uno o más orificios de purga para impactar de forma disruptiva la parte del flujo de aire que transporta el medicamento en polvo arrastrado.

10. 发明专利

DK1960021T3 Forgreningsrør til brug i medikamentdispenser 未知
公开(公告)号：DK1960021T3
公开(公告)日：2019-01-02
申请号：DK06820477
申请日：2006-12-11
申请人： GLAXO GROUP LTD
发明人： DAVIES MICHAEL BIRSHA , HAILEY MARK ANDREW , PALMER MARK GREGORY , WALKER RICHARD IAN
IPC分类号： A61M15/00 , A61M16/12

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