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    • 1. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008110584A3
    • 2008-11-27
    • PCT/EP2008052967
    • 2008-03-12
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASELLIMAN DAVID VINCENTKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • ANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASELLIMAN DAVID VINCENTKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • A61M15/00
    • A61M15/009A61M15/0026A61M15/0075A61M15/0091A61M15/0096A61M2205/6081G06M1/04G06M1/083
    • One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; an actuation counter; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to both move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism and also to actuate the actuation counter until a pre-determined threshold force is overcome.
    • 一方面提供了一种药物分配器装置,其包括壳体; 从壳体延伸,用于插入患者体腔中的出口; 所述药物排出装置具有纵向轴线并且包括用于储存待分配的药物制剂的容器,排出机构和从容器排出药物制剂到排出口的排出通道 ; 连接到所述容器,连接到所述排放装置的容器套环; 连接到所述容器套环并且能够沿着所述药物排放装置的纵向轴线相对于所述容器套环移动;传递元件,所述传递元件包括致动部分; 提供给所述壳体的至少一个手指可操作构件,所述至少一个手指可操作构件可移动以向所述传递元件的所述致动部分施加力以沿着所述纵向轴线在第一方向上移动所述传递元件; 将所述容器套环与所述传递元件联接;偏置机构,用于在所述传递元件沿着所述纵向轴线在所述第一方向上移动时存储偏置能量; 一个致动计数器; 并向容器套环提供预加载机构以防止偏置能量传递到容器套环以使药物排放装置沿第一方向沿纵向轴线移动以致动排放机构并且还致动致动计数器 直到克服预定的阈值力。
    • 2. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008023019A3
    • 2008-05-29
    • PCT/EP2007058679
    • 2007-08-21
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • ANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • B05B11/00A61M15/00
    • A61M15/009A61M15/0025A61M15/0075A61M15/0081A61M15/0096A61M2205/276A61M2205/8281B65D83/16
    • There is provided a drug dispenser device (1) comprising a housing (10a, 10b, 12), extending from the housing, an outlet (16) for insertion into a body-cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger (20a, 20b) operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction, linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome.
    • 提供了一种药物分配器装置(1),其包括从壳体延伸的壳体(10a,10b,12),用于插入患者体腔的出口(16); 提供给壳体并相对于其可移动的药物排出装置,具有纵向轴线并包括用于储存待分配的药物制剂的容器,排出机构和来自容器的排出通道,用于将药物制剂排出到出口 ; 连接到药物排出装置,容器衣领; 连接到所述容器套环并且沿着所述药物排出装置的纵向轴线可相对于其移动;转移元件,所述转移元件包括致动部分; 提供给壳体的至少一个手指(20a,20b)可操作构件可移动以对传递元件的致动部分施加力,以沿第一方向沿着纵向轴线移动传递元件,将容器环与传送件 元件,偏置机构,用于在第一方向沿着纵向轴线移动传递元件时存储偏置能量; 并且提供给所述容器套环,所述预加载机构用于防止所述偏置能量转移到所述容器套环,以沿所述纵向轴线沿所述第一方向移动所述药物排出装置,以启动所述排放机构,直到预定的阈值力为 克服。
    • 9. 发明申请
    • A COUNTER AND A RECORDER FOR A PILL DISPENSER
    • 计数器和记录器用于药片分配器
    • WO2008003759A3
    • 2008-06-05
    • PCT/EP2007056841
    • 2007-07-05
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCOLLINS JAMES TERENCEPEARSON ALLEN JOHN
    • ANDERSON GREGOR JOHN MCLENNANCOLLINS JAMES TERENCEPEARSON ALLEN JOHN
    • A61J7/02
    • A61J7/02G06M1/041G06M3/12
    • A counter (or recorder) for a pill dispenser (24), the counter (or recorder) comprising two relatively moveable chassis components (50, 52) forming part of a pill dispensement mechanism (21), a pill delivery or dispensement channel (32) for a pill or tablet (28) to pass through for dispensement and a counting (or recording) mechanism. The counting (or recording) mechanism comprises one or more actuation indicators (11), a ratchet pawl (14) for incrementally advancing a first (12) of the one or more actuation indicators (11) and a drive mechanism (16) for activating the ratchet pawl (14). The ratchet pawl (14) is mounted to a first of the two chassis components (50, 52). The drive mechanism (16) is mounted to the second of the two chassis components (50, 52). By this arrangement, by moving the two chassis components (50, 52) relative to each other, the drive mechanism (16) is moved relative to the ratchet pawl (14) and the pill dispensement mechanism (21) is actuated. The drive mechanism (16) is connected to a pill detect feature (18) that can move between a positive dispensement position and a negative dispensement position if the channel (32) is clear, the negative dispensement position being such that at least a part of the pill detect feature (18) is positioned within or blocking the pill delivery or dispensement channel (32), whereby the non-presence of a pill (28) within the channel (32) for dispensement, and therefore a failed dispensement, is confirmed. The movement from the positive dispensement position to the negative dispensement position prevents the drive mechanism (16) from activating the ratchet pawl (14) as the drive mechanism (16) moves relative to the ratchet pawl (16).
    • 用于药丸分配器(24)的计数器(或记录器),计数器(或记录器)包括形成药丸分配机构(21)的一部分的两个可相对移动的底盘部件(50,52),药丸输送或分配通道 )用于药丸或药片(28)通过分配和计数(或记录)机制。 计数(或记录)机构包括一个或多个致动指示器(11),用于递增地推进一个或多个致动指示器(11)中的第一个(12)的棘轮棘爪(14)以及用于激活 棘爪(14)。 棘爪(14)安装在两个底盘部件(50,52)中的第一个上。 驱动机构(16)安装到两个底盘部件(50,52)中的第二个。 通过这种布置,通过相对于彼此移动两个底盘部件(50,52),驱动机构(16)相对于棘轮爪(14)移动并且药丸分配机构(21)被致动。 如果通道(32)清澈,则驱动机构(16)连接到药丸检测特征(18),其可在正分配位置和负分配位置之间移动,负分配位置使得 药丸检测特征(18)定位在药丸递送或分配通道(32)内或阻塞药丸递送或分配通道(32),由此确认通道(32)内不存在用于分配并因此分配失败的药丸(28) 。 当驱动机构16相对于棘轮爪16移动时,从正分配位置到负分配位置的移动防止驱动机构16启动棘轮爪14。
    • 10. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008023017A3
    • 2008-05-29
    • PCT/EP2007058676
    • 2007-08-21
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANRAND PAUL KENNETH
    • ANDERSON GREGOR JOHN MCLENNANRAND PAUL KENNETH
    • A61M15/00
    • A61M15/009A61M15/00A61M15/0001A61M15/0021A61M15/0075A61M15/0081
    • There is provided a drug dispenser device comprising a housing defining a first chamber; extending from said housing and defining a second open chamber, an outlet for insertion into a body cavity of a patient; provided to said first chamber of the housing, a discharge block defining a discharge block orifice; receivable within the first chamber for movement therewithin, a drug discharge device, said drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from said container, wherein said discharge channel is receivable by said discharge block to enable discharge of said drug formulation via said discharge block orifice to said outlet; provided to the housing; and at least one finger operable member moveable to apply a force directly or indirectly to the drug discharge device for movement along the longitudinal axis towards the discharge block to actuate said discharge mechanism. The housing further defines an aperture through which said at least one finger operable member in part protrudes, and wherein the at least one finger operable member is moveable from a rest position in which the at least one finger operable member acts to block off said aperture to an actuating position in which the aperture is unblocked and through which air may be drawn into the housing in response to patient inhalation through the outlet.
    • 提供了一种药物分配器装置,其包括限定第一腔室的壳体; 从所述壳体延伸并且限定第二开放室,用于插入患者体腔的出口; 提供到所述壳体的所述第一腔室,排出块限定排出块孔口; 在第一室内可接收用于在其中移动的药物排出装置,所述药物排出装置具有纵向轴线并且包括用于储存待分配的药物制剂的容器,排出机构和来自所述容器的排出通道,其中所述排出通道 可由所述排放块接收,以使所述药物制剂经由所述排放块孔口排放到所述出口; 提供给住房; 以及至少一个手指可操作构件,其可移动以直接或间接施加力到所述药物排出装置,以沿着所述纵向轴线朝向所述排放块移动以致动所述排放机构。 所述外壳还限定一个孔,所述至少一个手指可操作构件部分穿过所述孔部分地突出,并且其中所述至少一个手指可操作构件可从静止位置移动,在所述静止位置,所述至少一个手指可操作构件用于阻挡所述孔, 响应于患者通过出口吸入,致动位置,其中孔被解开并且空气可以被吸入壳体中。