专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO0002621A9 SKIN AND MUSCLE-TARGETED GENE THERAPY BY PULSED ELECTRICAL FIELD 审中-公开
标题翻译：皮肤和肌肉靶向基因治疗的脉冲电场
公开(公告)号：WO0002621A9
公开(公告)日：2000-03-23
申请号：PCT/US9915755
申请日：1999-07-13
申请人： GENETRONICS INC , DEV NAGENDU B , HOFMANN GUNTER A , NOLAN EDWARD , RABUSSAY DIETMAR , TONNESSEN ARNT , WIDERA GEORG , ZHANG LEI
发明人： DEV NAGENDU B , HOFMANN GUNTER A , NOLAN EDWARD , RABUSSAY DIETMAR , TONNESSEN ARNT , WIDERA GEORG , ZHANG LEI
IPC分类号： A61N1/30 , A61N1/32
CPC分类号： A61N1/327 , A61N1/0424 , A61N1/0452 , A61N1/306 , A61N1/325
摘要： The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
摘要翻译：本发明描述了一种体内方法，其使用脉冲电场将治疗剂递送到皮肤和肌肉细胞中进行局部和全身治疗。具体而言，治疗剂包括裸露或配制的核酸，多肽和化学治疗剂。

2. 发明专利

DE69927388T2 未知
公开(公告)号：DE69927388T2
公开(公告)日：2006-07-13
申请号：DE69927388
申请日：1999-05-14
申请人： GENETRONICS INC
发明人： HOFFMAN A , RABUSSAY DIETMAR , TONNESSEN ARNT
IPC分类号： A61N1/32 , C12N15/09 , A61M37/00 , A61N1/30 , C12M1/00 , C12Q1/68
摘要： An electrode assembly for an apparatus for trans-surface molecular includes a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a plurality of first electrodes disposed on the proximal surface, a first conductor disposed on at least a first portion of the distal surface and extending through at least a first portion of the plurality of through holes and connected to the first electrodes on the proximal surface, a plurality of second electrodes disposed on the proximal surface, and a second conductor disposed on at least a second portion of the distal surface and extending through at least a second portion of the plurality of through holes and connected to the second electrodes on the proximal surface, wherein the first electrodes and the second electrodes are configured and disposed in closely spaced relation on the proximal surface for engaging the tissue surface and applying an electric field.

3. 发明专利

CA2340075A1 APPARATUS AND METHOD FOR THE DELIVERY OF DRUGS AND GENES INTO TISSUE 未知
公开(公告)号：CA2340075A1
公开(公告)日：2000-02-24
申请号：CA2340075
申请日：1999-05-14
申请人： GENETRONICS INC
发明人： HOFFMAN GUNTER A , TONNESSEN ARNT , RABUSSAY DIETMAR
IPC分类号： C12N15/09 , A61M37/00 , A61N1/30 , A61N1/32 , C12M1/00 , C12Q1/68
摘要： An electrode assembly for an apparatus for and a method of trans-surface molecular delivery, including a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proxima l surface to the distal surface, a first electrode disposed on at least a portion of the distal surface and extending through at least a portion of th e plurality of through holes and onto at least a portion of the proximal surface, a second electrode disposed on at least a portion of the proximal surface and in closely spaced relation with the first electrode for engaging a tissue surface through which to apply an electric field, and an insulating barrier that is disposed on at least a portion of the proximal surface of th e carrier between the first electrode and the second electrode.

4. 发明专利

CA2337652A1 SKIN AND MUSCLE-TARGETED GENE THERAPY BY PULSED ELECTRICAL FIELD 未知
公开(公告)号：CA2337652A1
公开(公告)日：2000-01-20
申请号：CA2337652
申请日：1999-07-13
申请人： GENETRONICS INC
发明人： ZHANG LEI , HOFMANN GUNTER A , NOLAN EDWARD , TONNESSEN ARNT , RABUSSAY DIETMAR , WIDERA GEORG , DEV NAGENDU B
IPC分类号： A61N1/30 , A61N1/32
摘要： The present invention describes an in vivo method, using pulsed electric fie ld to deliver therapeutic agents into cells of the skin and muscle for local an d systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.

5. 发明专利

DE69927388D1 未知
公开(公告)号：DE69927388D1
公开(公告)日：2005-10-27
申请号：DE69927388
申请日：1999-05-14
申请人： GENETRONICS INC
发明人： HOFFMAN A , RABUSSAY DIETMAR , TONNESSEN ARNT
IPC分类号： C12N15/09 , A61M37/00 , A61N1/30 , A61N1/32 , C12M1/00 , C12Q1/68
摘要： An electrode assembly for an apparatus for trans-surface molecular includes a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a plurality of first electrodes disposed on the proximal surface, a first conductor disposed on at least a first portion of the distal surface and extending through at least a first portion of the plurality of through holes and connected to the first electrodes on the proximal surface, a plurality of second electrodes disposed on the proximal surface, and a second conductor disposed on at least a second portion of the distal surface and extending through at least a second portion of the plurality of through holes and connected to the second electrodes on the proximal surface, wherein the first electrodes and the second electrodes are configured and disposed in closely spaced relation on the proximal surface for engaging the tissue surface and applying an electric field.

6. 发明专利

AU769758B2 Apparatus and method for the delivery of drugs and genes into tissue 未知
公开(公告)号：AU769758B2
公开(公告)日：2004-02-05
申请号：AU3991299
申请日：1999-05-14
申请人： GENETRONICS INC
发明人： HOFFMAN GUNTER A , RABUSSAY DIETMAR , TONNESSEN ARNT
IPC分类号： C12N15/09 , A61M37/00 , A61N1/30 , A61N1/32 , C12M1/00 , C12Q1/68
摘要： An electrode assembly for an apparatus for trans-surface molecular includes a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a plurality of first electrodes disposed on the proximal surface, a first conductor disposed on at least a first portion of the distal surface and extending through at least a first portion of the plurality of through holes and connected to the first electrodes on the proximal surface, a plurality of second electrodes disposed on the proximal surface, and a second conductor disposed on at least a second portion of the distal surface and extending through at least a second portion of the plurality of through holes and connected to the second electrodes on the proximal surface, wherein the first electrodes and the second electrodes are configured and disposed in closely spaced relation on the proximal surface for engaging the tissue surface and applying an electric field.

7. 发明专利

AU3991299A Apparatus and method for the delivery of drugs and genes into tissue 未知
公开(公告)号：AU3991299A
公开(公告)日：2000-03-06
申请号：AU3991299
申请日：1999-05-14
申请人： GENETRONICS INC
发明人： HOFFMAN GUNTER A , RABUSSAY DIETMAR , TONNESSEN ARNT
IPC分类号： C12N15/09 , A61M37/00 , A61N1/30 , A61N1/32 , C12M1/00 , C12Q1/68
摘要： An electrode assembly for an apparatus for trans-surface molecular includes a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a plurality of first electrodes disposed on the proximal surface, a first conductor disposed on at least a first portion of the distal surface and extending through at least a first portion of the plurality of through holes and connected to the first electrodes on the proximal surface, a plurality of second electrodes disposed on the proximal surface, and a second conductor disposed on at least a second portion of the distal surface and extending through at least a second portion of the plurality of through holes and connected to the second electrodes on the proximal surface, wherein the first electrodes and the second electrodes are configured and disposed in closely spaced relation on the proximal surface for engaging the tissue surface and applying an electric field.

8. 发明专利

AU4988399A Skin and muscle-targeted gene therapy by pulsed electrical field 未知
公开(公告)号：AU4988399A
公开(公告)日：2000-02-01
申请号：AU4988399
申请日：1999-07-13
申请人： GENETRONICS INC
发明人： DEV NAGENDU B , HOFMANN GUNTER A , NOLAN EDWARD , RABUSSAY DIETMAR , TONNESSEN ARNT , WIDERA GEORG , ZHANG LEI
IPC分类号： A61N1/30 , A61N1/32
摘要： The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.

9. 发明专利

CA2337652C SKIN AND MUSCLE-TARGETED GENE THERAPY BY PULSED ELECTRICAL FIELD 未知
公开(公告)号：CA2337652C
公开(公告)日：2013-03-26
申请号：CA2337652
申请日：1999-07-13
申请人： GENETRONICS INC
发明人： DEV NAGENDU B , HOFMANN GUNTER A , NOLAN EDWARD , RABUSSAY DIETMAR , TONNESSEN ARNT , WIDERA GEORG , ZHANG LEI
IPC分类号： A61N1/30 , A61M37/00 , A61N1/32
摘要： The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.

10. 发明专利

AU769758C Apparatus and method for the delivery of drugs and genes into tissue 未知
公开(公告)号：AU769758C
公开(公告)日：2007-09-06
申请号：AU3991299
申请日：1999-05-14
申请人： GENETRONICS INC
发明人： HOFFMAN GUNTER A , RABUSSAY DIETMAR , TONNESSEN ARNT
IPC分类号： C12N15/09 , A61M37/00 , A61N1/30 , A61N1/32 , C12M1/00 , C12Q1/68
摘要： An electrode assembly for an apparatus for trans-surface molecular includes a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a plurality of first electrodes disposed on the proximal surface, a first conductor disposed on at least a first portion of the distal surface and extending through at least a first portion of the plurality of through holes and connected to the first electrodes on the proximal surface, a plurality of second electrodes disposed on the proximal surface, and a second conductor disposed on at least a second portion of the distal surface and extending through at least a second portion of the plurality of through holes and connected to the second electrodes on the proximal surface, wherein the first electrodes and the second electrodes are configured and disposed in closely spaced relation on the proximal surface for engaging the tissue surface and applying an electric field.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式