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1. 发明申请

WO2005123110A3 COMPOSITIONS COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF 审中-公开
公开(公告)号：WO2005123110A3
公开(公告)日：2005-12-29
申请号：PCT/US2005/020899
申请日：2005-06-09
申请人： GENENCOR INTERNATIONAL, INC. , DOW CORNING CORPORATION , BOTT, Richard R. , JENSEN, Rasmus B. , KELEMEN, Bradley , WARD II, Donald E. , WHITED, Gregory M.
发明人： BOTT, Richard R. , JENSEN, Rasmus B. , KELEMEN, Bradley , WARD II, Donald E. , WHITED, Gregory M.
IPC分类号： C07K1/00 , G11B7/085 , G11B7/00
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal- containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.

2. 发明授权

EP1753997B1 PHOTOCHROMIC MATERIAL COMPRISING A PROTEORHODOPSIN APOPROTEIN AND RETINAL ANALOG 有权
标题翻译： WITH A遗传工程脱辅基蛋白及RETINALANALOGON PHOTO铬合金材料
公开(公告)号：EP1753997B1
公开(公告)日：2009-10-28
申请号：EP05771676.3
申请日：2005-06-09
申请人： GENENCOR INTERNATIONAL, INC. , Dow Corning Corporation
发明人： JENSEN, Rasmus, B. , KELEMEN, Bradley , WARD, Donald, E., II , ASATO, Alfred, E.
IPC分类号： A61K31/07 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/275 , A61K38/17 , C07C47/225 , C07C47/24 , C07C47/548 , G02B5/23
CPC分类号： C07C403/14 , A61K31/07 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/275 , A61K38/1709 , C07C47/225 , C07C47/24 , C07C47/548 , C07C2601/16 , C07C2602/30 , G02B5/23 , A61K2300/00

3. 发明公开

EP1753997A1 PHOTOCHROMIC MATERIAL COMPRISING A PROTEORHODOPSIN APOPROTEIN AND RETINAL ANALOG 有权
标题翻译： FOTOCHROMES MATERIAL MIT EINEM PROTEOROODOPSIN-APOPROTEIN UND RETINALANALOGON
公开(公告)号：EP1753997A1
公开(公告)日：2007-02-21
申请号：EP05771676.3
申请日：2005-06-09
申请人： GENENCOR INTERNATIONAL, INC. , Dow Corning Corporation
发明人： JENSEN, Rasmus, B. , KELEMEN, Bradley , WARD, Donald, E., II , ASATO, Alfred, E.
IPC分类号： F21V9/00
CPC分类号： C07C403/14 , A61K31/07 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/275 , A61K38/1709 , C07C47/225 , C07C47/24 , C07C47/548 , C07C2601/16 , C07C2602/30 , G02B5/23 , A61K2300/00
摘要： The present invention relates to a photochromic material comprising a proteorhodopsin apoprotein and a retinal analog. In one embodiment, the retinal analog is an azulenic retinoid compound. In another embodiment, the retinal analog is other compound that is structurally similarly to all-trans-retinal. The proteorhodopsin apoprotein and the retinal analog form a photochromic material having different spectral properties from those of a corresponding photochromic material formed by the same proteorhodopsin apoprotein and all-trans-retinal. In one embodiment of the application, the retinal analog-containing proteorhodopsin has an absorbance spectrum that does not overlap significantly with that of all-trans-retinal-containing proteorhodopsin. In another embodiment of the application, the retinal analog-containing proteorhodopsin yields a red-shifted visual chromophore compared with the all-trans-retinal-containing proteorhodopsin chromophore. The photochromic material of the present invention is useful as an optical data storage carrier, a fraud-proof optical data carrier, security ink, and in other optical applications.
摘要翻译：本发明涉及包含蛋白质视紫红质脱辅基蛋白和视网膜类似物的光致变色材料。在一个实施方案中，视黄醛类似物是靛蓝色素类化合物。在另一个实施方案中，视黄醛类似物是在结构上类似于全反式视黄醛的化合物。蛋白质视紫红质脱蛋白和视网膜类似物形成与由相同的蛋白质视网膜脱辅基蛋白和全反式视网膜形成的相应的光致变色材料的光谱性质不同的光致变色材料。在本申请的一个实施方案中，含视网膜类似物的蛋白质视紫红质具有与全反式视网膜含蛋白质视紫红质不显着重叠的吸收光谱。在本申请的另一个实施方案中，与含全反式视网膜的蛋白质视紫红质发色团相比，含视网膜类似物的蛋白质视紫红质产生红移视觉发色团。本发明的光致变色材料可用作光学数据存储载体，防欺诈光学数据载体，安全墨水以及其它光学应用。

4. 发明公开

EP1753448A2 COMPOSITIONS COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF 有权
标题翻译：包含各种蛋白质和/或细菌体的组合物及其用途
公开(公告)号：EP1753448A2
公开(公告)日：2007-02-21
申请号：EP05761082.6
申请日：2005-06-09
申请人： GENENCOR INTERNATIONAL, INC. , DOW CORNING CORPORATION
发明人： BOTT, Richard R. , JENSEN, Rasmus B. , KELEMEN, Bradley , WARD II, Donald E. , WHITED, Gregory M.
IPC分类号： A61K38/17
CPC分类号： G11C7/00 , C07K14/215 , C09D11/037 , C09D11/50 , G11B7/242 , Y10S430/146 , Y10T428/249921 , Y10T428/31623 , Y10T428/31685 , Y10T428/31725 , Y10T428/31783
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal- containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.
摘要翻译：本发明提供一种固体材料，其包含两种或更多种proteorhodopsins，两种或更多种细菌视紫红质或一种或更多种细菌视紫红质和一种或更多种proteorhodopsins的固定化混合物。该proteorhodopsins选自全反式视网膜proteorhodopsins和含视网膜类似物proteorhodopsins; 所有这些都具有不重叠的吸收光谱。细菌视紫红质选自含全反式视黄醛的细菌视紫红质和含视网膜模拟物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料和塑料材料，其中所述固体材料沉积在所述基材上。本发明进一步提供包含一种或多种亲水性聚合物和各种光致变色材料的混合物的安全油墨。

5. 发明申请

WO2005124230A1 PHOTOCHROMIC MATERIAL COMPRISING A PROTEORHODOPSIN APOPROTEIN AND RETINAL ANALOG 审中-公开
标题翻译：包含抗原蛋白磷酸化蛋白和视黄细胞模拟物的光致变色材料
公开(公告)号：WO2005124230A1
公开(公告)日：2005-12-29
申请号：PCT/US2005/020900
申请日：2005-06-09
申请人： GENENCOR INTERNATIONAL, INC. , DOW CORNING , JENSEN, Rasmus, B. , KELEMEN, Bradley , WARD, Donald, E., II , ASATO, Alfred, E.
发明人： JENSEN, Rasmus, B. , KELEMEN, Bradley , WARD, Donald, E., II , ASATO, Alfred, E.
IPC分类号： F21V9/00
CPC分类号： C07C403/14 , A61K31/07 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/275 , A61K38/1709 , C07C47/225 , C07C47/24 , C07C47/548 , C07C2601/16 , C07C2602/30 , G02B5/23 , A61K2300/00
摘要： The present invention relates to a photochromic material comprising a proteorhodopsin apoprotein and a retinal analog. In one embodiment, the retinal analog is an azulenic retinoid compound. In another embodiment, the retinal analog is other compound that is structurally similarly to all-trans-retinal. The proteorhodopsin apoprotein and the retinal analog form a photochromic material having different spectral properties from those of a corresponding photochromic material formed by the same proteorhodopsin apoprotein and all-trans-retinal. In one embodiment of the application, the retinal analog-containing proteorhodopsin has an absorbance spectrum that does not overlap significantly with that of all-trans-retinal-containing proteorhodopsin. In another embodiment of the application, the retinal analog-containing proteorhodopsin yields a red-shifted visual chromophore compared with the all-trans-retinal-containing proteorhodopsin chromophore. The photochromic material of the present invention is useful as an optical data storage carrier, a fraud-proof optical data carrier, security ink, and in other optical applications.
摘要翻译：本发明涉及包含蛋白质视紫红质脱辅蛋白和视网膜类似物的光致变色材料。在一个实施方案中，视黄醛类似物是靛蓝色素类化合物。在另一个实施方案中，视黄醛类似物是在结构上类似于全反式视黄醛的其它化合物。蛋白质视紫红质脱辅基蛋白和视网膜类似物形成与由相同的蛋白质视紫红质脱蛋白和全反式视网膜形成的相应的光致变色材料具有不同光谱性质的光致变色材料。在本申请的一个实施方案中，含视网膜类似物的蛋白质视紫红质具有与全反式视黄醛的蛋白质视紫红质相似的吸收光谱。在本申请的另一个实施方案中，与含全反式视网膜的蛋白质视紫红质发色团相比，含视网膜类似物的蛋白质视紫红质产生红移视觉发色团。本发明的光致变色材料可用作光学数据存储载体，防欺诈光学数据载体，安全墨水以及其它光学应用。

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