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1. 发明授权

US09888896B2 Determining a three-dimensional model dataset of a blood vessel system with at least one vessel segment 有权
公开(公告)号：US09888896B2
公开(公告)日：2018-02-13
申请号：US14789413
申请日：2015-07-01
申请人： Günter Lauritsch , Thomas Redel , Christopher Rohkohl , Michael Scheuering
发明人： Günter Lauritsch , Thomas Redel , Christopher Rohkohl , Michael Scheuering
IPC分类号： G06T11/60 , A61B6/00 , G06T17/00 , A61B6/03
CPC分类号： A61B6/504 , A61B6/032 , A61B6/4441 , A61B6/5205 , A61B6/5288 , A61B6/5294 , G06T11/60 , G06T17/00 , G06T2200/04 , G06T2210/41
摘要： A three-dimensional model dataset of a blood vessel system of a patient including at least one the vessel system is determined from a number of projection images, which have been recorded from different recording angles, of the blood vessel system The projection images are divided up into image areas each containing at least one pixel. A feature vector is determined for each of the image areas. Classification information, which describes how the respective image area belongs or does not belong to a vessel segment of the blood vessel system defined in accordance with anatomical specification data, is defined for each of the image areas by applying a classification function to the feature vector assigned to the image area. The classification function has been trained by training data records annotated with classification information obtained from at least one person other than the patient. The blood vessel system in the projection images is segmented by grouping image areas with the same classification information. The three-dimensional model dataset is calculated as a function of the segmented projection images and the classification information.

2. 发明申请

US20160012636A1 Determining a Three-dimensional Model Dataset of a Blood Vessel System with at least One Vessel Segment 有权
标题翻译：确定具有至少一个血管段的血管系统的三维模型数据集
公开(公告)号：US20160012636A1
公开(公告)日：2016-01-14
申请号：US14789413
申请日：2015-07-01
申请人： Günter Lauritsch , Thomas Redel , Christopher Rohkohl , Michael Scheuering
发明人： Günter Lauritsch , Thomas Redel , Christopher Rohkohl , Michael Scheuering
IPC分类号： G06T17/10 , A61B6/03 , A61B6/00 , G06T11/60
CPC分类号： A61B6/504 , A61B6/032 , A61B6/4441 , A61B6/5205 , A61B6/5288 , A61B6/5294 , G06T11/60 , G06T17/00 , G06T2200/04 , G06T2210/41
摘要： A three-dimensional model dataset of a blood vessel system of a patient including at least one the vessel system is determined from a number of projection images, which have been recorded from different recording angles, of the blood vessel system The projection images are divided up into image areas each containing at least one pixel. A feature vector is determined for each of the image areas. Classification information, which describes how the respective image area belongs or does not belong to a vessel segment of the blood vessel system defined in accordance with anatomical specification data, is defined for each of the image areas by applying a classification function to the feature vector assigned to the image area. The classification function has been trained by training data records annotated with classification information obtained from at least one person other than the patient. The blood vessel system in the projection images is segmented by grouping image areas with the same classification information. The three-dimensional model dataset is calculated as a function of the segmented projection images and the classification information.
摘要翻译：包括至少一个血管系统的患者的血管系统的三维模型数据集是从血管系统的不同记录角度记录的多个投影图像确定的。将投影图像分割到每个包含至少一个像素的图像区域中。为每个图像区域确定特征向量。通过对分配的特征矢量应用分类函数，对每个图像区域分别描述各个图像区域属于或不属于根据解剖规范数据定义的血管系统的血管段的分类信息到图像区域。分类功能已经通过训练用从患者以外的至少一个人获得的分类信息注释的数据记录来训练。投影图像中的血管系统通过对具有相同分类信息的图像区域进行分组。三维模型数据集被计算为分段投影图像和分类信息的函数。

3. 发明授权

US09013471B2 3D X-ray imaging of coronary vessels with ECG gating and motion correction 有权
标题翻译：冠脉血管的3D X线成像与ECG门控和运动校正
公开(公告)号：US09013471B2
公开(公告)日：2015-04-21
申请号：US13152367
申请日：2011-06-03
申请人： Günter Lauritsch , Christopher Rohkohl
发明人： Günter Lauritsch , Christopher Rohkohl
IPC分类号： G06T15/00 , A61B6/00 , G06T11/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/4458 , A61B6/5264 , A61B6/5288 , A61B6/541 , G06T11/005 , G06T2211/412 , G06T2211/424
摘要： A method for three-dimensional visualization of a moving structure by a rotation angiography method is described. A series of projection images is recorded by an image acquisition unit from different recording angles during a rotation cycle. A three-dimensional image data can be reconstructed from the projection images. A continuous rotation cycle is proposed to be performed with simultaneous recording of at least one ECG. A three-dimensional reconstructed reference image is generated through a first correction of the motion of the moving structure by affine transformations. A three-dimensional image data of the moving structure is reconstructed from the data acquired in the continuous rotation cycle when using the reconstructed reference image while performing an estimation and correction of the motion by elastic deformations.
摘要翻译：描述了通过旋转血管造影方法对运动结构进行三维可视化的方法。在旋转周期期间，图像采集单元从不同的记录角度记录一系列投影图像。可以从投影图像重建三维图像数据。提出连续旋转周期，同时记录至少一个ECG。通过仿射变换对运动结构的运动进行第一次校正来生成三维重建参考图像。当通过弹性变形执行运动的估计和校正时，在使用重建的参考图像时，从连续旋转周期中获取的数据重构运动结构的三维图像数据。

4. 发明申请

US20130004052A1 SUBTRACTION OF PROJECTION DATA IN MEDICAL DIAGNOSTIC IMAGING 有权
标题翻译：投影数据在医学诊断成像中的分类
公开(公告)号：US20130004052A1
公开(公告)日：2013-01-03
申请号：US13533314
申请日：2012-06-26
申请人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06T7/251 , G06T11/005 , G06T2207/10081 , G06T2207/30048 , G06T2211/412
摘要： Background information is subtracted from projection data in medical diagnostic imaging. The background is removed using data acquired in a single rotational sweep of a C-arm. The removal may be by masking out a target, leaving the background, in the data as constructed into a volume. For subtraction, the masked background information is projected to a plane and subtracted from the data representing the plane.
摘要翻译：医疗诊断成像中的投影数据中减去背景信息。使用在C臂的单次旋转扫描中获取的数据来去除背景。删除可能是通过将构建成一个卷的数据中的一个目标掩盖掉，留下背景。对于减法，将掩蔽的背景信息投影到平面，并从表示平面的数据中减去。

5. 发明授权

US08634620B2 Method for supplying a 3D X-ray image data record for a moving object with highly absorbent material 有权
标题翻译：用于为具有高吸收性材料的移动物体提供3D X射线图像数据记录的方法
公开(公告)号：US08634620B2
公开(公告)日：2014-01-21
申请号：US13456480
申请日：2012-04-26
申请人： Jan Boese , Günter Lauritsch , Christopher Rohkohl , Bernhard Scholz
发明人： Jan Boese , Günter Lauritsch , Christopher Rohkohl , Bernhard Scholz
IPC分类号： G06K9/00
CPC分类号： A61B6/503 , A61B5/7207 , A61B6/5223 , A61B6/5258 , A61B6/5264 , G06T11/005 , G06T11/006 , G06T2211/412
摘要： A method is provided for supplying a 3D X-ray image data record for a moving object. The said object contains highly X-ray radiation-absorbent material. A correction is made in respect of the highly absorbent material in 2D forward projections obtained from a 3D-X-ray image data record. The forward projections are calculated using 3D motion fields, which are derived from original 2D X-ray image data records.
摘要翻译：提供了一种用于为运动物体提供3D X射线图像数据记录的方法。所述物体包含高X射线吸收材料。对从3D-X射线图像数据记录获得的2D向前投影中的高吸收性材料进行校正。使用从原始2D X射线图像数据记录导出的3D运动场来计算向前投影。

6. 发明申请

US20130004040A1 LEFT VENTRICLE EPICARDIUM ESTIMATION IN MEDICAL DIAGNOSTIC IMAGING 有权
标题翻译：医学诊断成像中的左心室环境评估
公开(公告)号：US20130004040A1
公开(公告)日：2013-01-03
申请号：US13533234
申请日：2012-06-26
申请人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/68
CPC分类号： G06T7/251 , G06T11/005 , G06T2207/10081 , G06T2207/30048 , G06T2211/412
摘要： The left ventricle epicardium is estimated in medical diagnostic imaging. C-arm x-ray data is used to detect an endocardium at different phases. The detected endocardium at the different phases is compared to sample endocardiums at different phases. The sample endocardiums have corresponding sample epicadriums. The transformation between the most similar sample endocardium or endocardiums over time and the detected endocardium over time is applied to the corresponding sample epicardium or epicardiums. The transformed sample epicardium over time is the estimated epicardium over time for the C-arm x-ray data.
摘要翻译：估计左心室心外膜在医学诊断成像中。 C臂X射线数据用于检测不同阶段的心内膜。将检测到的不同阶段的心内膜与不同阶段的样品心内膜进行比较。样品心内膜具有相应的样品epicadrium。随着时间的推移，最相似的样品心内膜或心内膜与随时间的检测到的心内膜之间的转化被应用于相应的样品心外膜或心外膜。随着时间的推移，转化的样品心外膜随着时间的推移，C-arm x射线数据的估计心外膜。

7. 发明申请

US20110298793A1 3D X-RAY IMAGING OF CORONARY VESSELS WITH ECG GATING AND MOTION CORRECTION 有权
标题翻译：冠状动脉的3D X射线成像与心电图和运动校正
公开(公告)号：US20110298793A1
公开(公告)日：2011-12-08
申请号：US13152367
申请日：2011-06-03
申请人： Günter Lauritsch , Christopher Rohkohl
发明人： Günter Lauritsch , Christopher Rohkohl
IPC分类号： G06T15/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/4458 , A61B6/5264 , A61B6/5288 , A61B6/541 , G06T11/005 , G06T2211/412 , G06T2211/424
摘要： A method for three-dimensional visualization of a moving structure by a rotation angiography method is described. A series of projection images is recorded by an image acquisition unit from different recording angles during a rotation cycle. A three-dimensional image data can be reconstructed from the projection images. A continuous rotation cycle is proposed to be performed with simultaneous recording of at least one ECG. A three-dimensional reconstructed reference image is generated through a first correction of the motion of the moving structure by affine transformations. A three-dimensional image data of the moving structure is reconstructed from the data acquired in the continuous rotation cycle when using the reconstructed reference image while performing an estimation and correction of the motion by elastic deformations.
摘要翻译：描述了通过旋转血管造影方法对运动结构进行三维可视化的方法。在旋转周期期间，图像采集单元从不同的记录角度记录一系列投影图像。可以从投影图像重建三维图像数据。提出连续旋转周期，同时记录至少一个ECG。通过仿射变换对运动结构的运动进行第一次校正来生成三维重建参考图像。当通过弹性变形执行运动的估计和校正时，在使用重建的参考图像时，从连续旋转周期中获取的数据重构运动结构的三维图像数据。

8. 发明申请

US20150036905A1 THREE-DIMENSIONAL X-RAY IMAGING 有权
标题翻译：三维X射线成像
公开(公告)号：US20150036905A1
公开(公告)日：2015-02-05
申请号：US13959011
申请日：2013-08-05
申请人： Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Chris Schwemmer
发明人： Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Chris Schwemmer
IPC分类号： G06T11/00 , G06T15/08 , A61B6/02
CPC分类号： G06T15/08 , G06T11/005 , G06T11/006 , G06T2211/412
摘要： A 3D result image of an object is reconstructed from a set of X-ray two-dimensional projections of the object. A 3D reference image of the object is reconstructed by employing a compressed sensing technique based on at least some of the 2D projections at a reference motion state of the object. By employing an algebraic and/or analytic reconstruction technique, 3D intermediate images are reconstructed for various motion states of the object. The 3D intermediate images are registered with the 3D reference image to obtain spatial transformations for the various motion states of the object. Based on the spatial transformations, the 3D intermediate images are transformed to a joint phase and combined to obtain the 3D result image.
摘要翻译：从对象的一组X射线二维投影重建对象的3D结果图像。通过使用基于对象的参考运动状态下的至少一些2D投影的压缩感测技术，来重建对象的3D参考图像。通过采用代数和/或分析重建技术，为对象的各种运动状态重建3D中间图像。 3D中间图像被注册到3D参考图像以获得用于对象的各种运动状态的空间变换。基于空间变换，将3D中间图像转换为联合相位并进行组合以获得3D结果图像。

9. 发明授权

US08183529B2 Method for three-dimensional presentation of a moved structure using a tomographic method 有权
标题翻译：使用断层摄影法对移动结构进行三维显示的方法
公开(公告)号：US08183529B2
公开(公告)日：2012-05-22
申请号：US12378793
申请日：2009-02-19
申请人： Joachim Hornegger , Günter Lauritsch , Marcus Prümmer , Christopher Rohkohl
发明人： Joachim Hornegger , Günter Lauritsch , Marcus Prümmer , Christopher Rohkohl
IPC分类号： G01T1/20 , G06K9/00 , A61N5/10
CPC分类号： A61B6/032 , A61B6/4441 , A61B6/466 , G06T11/005 , G06T2211/412
摘要： The invention relates to a method for three-dimensional presentation of a moved structure using a tomographic method, in which a plurality of projection images are recorded from different imaging angles between a start angle with a start node point and an end angle with an end node point by an imaging unit during a number of rotation passes, with three-dimensional image data being able to be reconstructed from the projection images, with the projection images being spaced by a path or an edge. For determining the three-dimensional presentation for each angle of projection only those projection images are selected which minimize the sum of the paths or weighted edges between adjacent projection angles for a gating.
摘要翻译：本发明涉及一种使用断层摄影方法对移动结构进行三维呈现的方法，其中从与起点节点的开始角度与终端节点的终止角度之间的不同成像角度记录多个投影图像在多次旋转通过期间由成像单元指向，其中三维图像数据能够从投影图像重建，其中投影图像被路径或边缘间隔开。为了确定每个投影角度的三维呈现，仅选择那些最小化用于门控的相邻投影角之间的路径或加权边缘之和的投影图像。

10. 发明授权

US09349197B2 Left ventricle epicardium estimation in medical diagnostic imaging 有权
标题翻译：医学诊断影像左心室心外膜估计
公开(公告)号：US09349197B2
公开(公告)日：2016-05-24
申请号：US13533234
申请日：2012-06-26
申请人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/00 , G06T11/00 , G06T7/20
CPC分类号： G06T7/251 , G06T11/005 , G06T2207/10081 , G06T2207/30048 , G06T2211/412
摘要： The left ventricle epicardium is estimated in medical diagnostic imaging. C-arm x-ray data is used to detect an endocardium at different phases. The detected endocardium at the different phases is compared to sample endocardiums at different phases. The sample endocardiums have corresponding sample epicardiums. The transformation between the most similar sample endocardium or endocardiums over time and the detected endocardium over time is applied to the corresponding sample epicardium or epicardiums. The transformed sample epicardium over time is the estimated epicardium over time for the C-arm x-ray data.
摘要翻译：估计左心室心外膜在医学诊断成像中。 C臂X射线数据用于检测不同阶段的心内膜。将检测到的不同阶段的心内膜与不同阶段的样品心内膜进行比较。样品心内膜具有相应的样品心外膜。随着时间的推移，最相似的样品心内膜或心内膜与随时间的检测到的心内膜之间的转化被应用于相应的样品心外膜或心外膜。随着时间的推移，转化的样品心外膜随着时间的推移，C-arm x射线数据的估计心外膜。

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