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1. 发明授权

US07803164B2 Method for guiding instruments having different sizes 有权
标题翻译：用于引导具有不同尺寸的仪器的方法
公开(公告)号：US07803164B2
公开(公告)日：2010-09-28
申请号：US11733368
申请日：2007-04-10
申请人： Frans L. H. Gielen , Peter Appenrodt , Paulus Cornelis Van Venrooij , Victor Duysens
发明人： Frans L. H. Gielen , Peter Appenrodt , Paulus Cornelis Van Venrooij , Victor Duysens
IPC分类号： A61B19/00
CPC分类号： A61B17/3403 , A61B34/20 , A61B34/70 , A61B90/11 , A61B2017/3407 , A61B2017/3411 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/256 , A61B2090/374 , A61B2090/376
摘要： A system and procedure for using the system are disclosed for guiding instruments of varying sizes. The instruments can be guided into various portions of the anatomy for performing a procedure, providing a treatment, measuring a physiological response, or the like. Two or more instruments of varying sizes can be driven or guided relative to one another with the same system.
摘要翻译：公开了用于引导不同尺寸的仪器的系统和程序。可以将器械引导到解剖结构的各个部分以执行手术，提供治疗，测量生理反应等。可以使用相同的系统相对于彼此驱动或引导两种或更多种不同尺寸的仪器。

2. 发明授权

US07879045B2 System for guiding instruments having different sizes 有权
标题翻译：用于引导具有不同尺寸的仪器的系统
公开(公告)号：US07879045B2
公开(公告)日：2011-02-01
申请号：US11733362
申请日：2007-04-10
申请人： Frans L. H. Gielen , Peter Appenrodt , Paulus Cornelis Van Venrooij , Victor Duysens
发明人： Frans L. H. Gielen , Peter Appenrodt , Paulus Cornelis Van Venrooij , Victor Duysens
IPC分类号： A61B19/00
CPC分类号： A61B17/3403 , A61B34/20 , A61B34/70 , A61B90/11 , A61B2017/3407 , A61B2017/3411 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/256 , A61B2090/374 , A61B2090/376 , A61B2090/3983
摘要： A system and procedure for using the system are disclosed for guiding instruments of varying sizes. The instruments can be guided into various portions of the anatomy for performing a procedure, providing a treatment, measuring a physiological response, or the like. Two or more instruments of varying sizes can be driven or guided relative to one another with the same system.
摘要翻译：公开了用于引导不同尺寸的仪器的系统和程序。可以将器械引导到解剖结构的各个部分以执行手术，提供治疗，测量生理反应等。可以使用相同的系统相对于彼此驱动或引导两种或更多种不同尺寸的仪器。

3. 发明申请

US20080255583A1 Method For Guiding Instruments Having Different Sizes 有权
标题翻译：引导不同尺寸仪器的方法
公开(公告)号：US20080255583A1
公开(公告)日：2008-10-16
申请号：US11733368
申请日：2007-04-10
申请人： Frans L.H. Gielen , Peter Appenrodt , Paulus Cornelis van Venrooij , Victor Duysens
发明人： Frans L.H. Gielen , Peter Appenrodt , Paulus Cornelis van Venrooij , Victor Duysens
IPC分类号： A61B19/00
CPC分类号： A61B17/3403 , A61B34/20 , A61B34/70 , A61B90/11 , A61B2017/3407 , A61B2017/3411 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/256 , A61B2090/374 , A61B2090/376
摘要： A system and procedure for using the system are disclosed for guiding instruments of varying sizes. The instruments can be guided into various portions of the anatomy for performing a procedure, providing a treatment, measuring a physiological response, or the like. Two or more instruments of varying sizes can be driven or guided relative to one another with the same system.
摘要翻译：公开了用于引导不同尺寸的仪器的系统和程序。可以将器械引导到解剖结构的各个部分以执行手术，提供治疗，测量生理反应等。可以使用相同的系统相对于彼此驱动或引导两种或更多种不同尺寸的仪器。

4. 发明申请

US20080255544A1 System for Guiding Instruments Having Different Sizes 有权
标题翻译：不同尺寸指导仪器系统
公开(公告)号：US20080255544A1
公开(公告)日：2008-10-16
申请号：US11733362
申请日：2007-04-10
申请人： Frans L.H. Gielen , Peter Appenrodt , Paulus Cornelis van Venrooij , Victor Duysens
发明人： Frans L.H. Gielen , Peter Appenrodt , Paulus Cornelis van Venrooij , Victor Duysens
IPC分类号： A61B17/00
CPC分类号： A61B17/3403 , A61B34/20 , A61B34/70 , A61B90/11 , A61B2017/3407 , A61B2017/3411 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/256 , A61B2090/374 , A61B2090/376 , A61B2090/3983
摘要： A system and procedure for using the system are disclosed for guiding instruments of varying sizes. The instruments can be guided into various portions of the anatomy for performing a procedure, providing a treatment, measuring a physiological response, or the like. Two or more instruments of varying sizes can be driven or guided relative to one another with the same system.
摘要翻译：公开了用于引导不同尺寸的仪器的系统和程序。可以将器械引导到解剖结构的各个部分以执行手术，提供治疗，测量生理反应等。可以使用相同的系统相对于彼此驱动或引导两种或更多种不同尺寸的仪器。

5. 发明申请

US20060184222A1 Medical electrical lead with interchangeable fixation member 审中-公开
标题翻译：医用电线带可互换固定件
公开(公告)号：US20060184222A1
公开(公告)日：2006-08-17
申请号：US11204749
申请日：2005-08-16
申请人： Antoine Camps , Victor Duysens , Leo Kretzers , Martin Gerber
发明人： Antoine Camps , Victor Duysens , Leo Kretzers , Martin Gerber
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/059
摘要： A medical electrical lead, a system for providing electrical stimulation or sensing using such a lead, and methods of implanting, making and using same are described. The lead includes a rapidly connectable and/or interchangeable distal line that may be attached to a connector located distally from a distal end of a stimulating electrode. The rapidly connectable or interchangeable line may be sutured to a patient's muscle or other tissue. A physician may select a distal suture line of the present invention on the basis of the desired characteristics of the line, and then connect, secure or attach same to the lead body just prior to the surgical operation in which the stimulating or sensing medical electrical lead of the present invention is to be employed. The desired characteristics of the suture line may relate to thickness or diameter, length, the material from which the line is made, biodegradability, and the like.
摘要翻译：描述了医用电线，用于提供使用这种引线的电刺激或感测的系统，以及植入，制造和使用它们的方法。引线包括可以连接到远离刺激电极的远端的连接器的可快速连接和/或可互换的远端线。可快速连接或可互换的线可以缝合到患者的肌肉或其他组织。医生可以根据线的期望特征选择本发明的远端缝合线，然后在外科手术之前连接，固定或连接到引线体，其中刺激或感测医用电线采用本发明。缝合线的期望特征可以涉及厚度或直径，长度，制造线的材料，生物降解性等。

6. 发明授权

US06980863B2 Neurological stimulation lead extension 有权
标题翻译：神经刺激引导延长
公开(公告)号：US06980863B2
公开(公告)日：2005-12-27
申请号：US10395321
申请日：2003-03-20
申请人： Paul van Venrooij , Victor Duysens
发明人： Paul van Venrooij , Victor Duysens
IPC分类号： A61N1/05 , A61N1/375 , H01R13/02 , H01R13/10 , H01R13/62 , H01R13/627 , H01R13/629 , H01R13/639 , H01R24/58
CPC分类号： A61N1/0529 , A61N1/0534 , A61N1/0539 , A61N1/0551 , A61N1/3752 , H01R13/025 , H01R13/10 , H01R13/62 , H01R13/6271 , H01R13/6273 , H01R13/629 , H01R13/62905 , H01R13/639 , H01R24/58 , H01R2107/00 , H01R2201/12
摘要： The invention is directed to neurological lead extensions without set screws, set screw blocks, or set screw inserts. Such elimination of set screws, blocks and inserts can reduce the amount of metal and ferromagnetic material in the extension. The neurological lead extension may include a proximal end configured to couple to a neurological device and a distal end configured to couple to an implanted neurological lead. A set of electrical contacts are disposed in proximity to the distal end to provide electrical contact to an inserted end of the implanted neurological lead. Various elements and structures are described which can mechanically secure the inserted end of the implanted neurological lead to the distal end of the extension.
摘要翻译：本发明涉及无固定螺钉，固定螺钉块或固定螺钉插入物的神经学引线延伸。固定螺钉，块和嵌件的这种消除可以减少延伸部分中的金属和铁磁材料的量。神经系统引导延伸可以包括被配置为耦合到神经学装置的近端和被配置为耦合到植入的神经学引线的远端。一组电触点设置在远端附近，以提供与植入的神经导联的插入端的电接触。描述了可以将植入的神经学引线的插入端机械地固定到延伸部的远端的各种元件和结构。

7. 发明授权

US07212867B2 Directional brain stimulation and recording leads 有权
标题翻译：定向脑刺激和记录线
公开(公告)号：US07212867B2
公开(公告)日：2007-05-01
申请号：US10008773
申请日：2001-12-05
申请人： Paul Van Venrooij , Frans H. Gielen , Keith R. Mullett , Victor Duysens , Dan Gruia
发明人： Paul Van Venrooij , Frans H. Gielen , Keith R. Mullett , Victor Duysens , Dan Gruia
IPC分类号： A61N1/05
CPC分类号： A61N1/0534 , A61N1/0531 , A61N1/36182
摘要： A directional brain stimulation lead assembly provides a lead body and an insulating member defining one or more windows that selectively expose portions of electrodes carried by the lead body to produce a directional stimulation current field. The lead assembly can achieve more effective localization of electrical stimulation to very small brain targets, and thereby reduce the incidence of material side effects caused by collateral stimulation of brain tissue adjoining a desired brain target. In addition, the directional lead can sense brain activity on a more localized basis.
摘要翻译：定向脑刺激引线组件提供引线体和限定一个或多个窗口的绝缘构件，所述窗口选择性地暴露由引线体承载的电极的部分以产生定向刺激电流场。引线组件可以实现电刺激对于非常小的脑靶标的更有效的定位，从而减少由毗邻刺激邻近期望的脑靶标的脑组织引起的材料副作用的发生。此外，方向引导可以在更本地化的基础上感测大脑活动。

8. 发明授权

US08244379B2 Pericardium fixation concepts of epicardium pacing leads and tools 有权
标题翻译：心包起搏导联和工具的心包固定概念
公开(公告)号：US08244379B2
公开(公告)日：2012-08-14
申请号：US11380234
申请日：2006-04-26
申请人： Koen Michels , Jean-Luc Jansens , Victor Duysens , Paulus G. Adams , Paulus Van Venrooij , Markus J. C. Lazeroms , Fredric W. Lindemans
发明人： Koen Michels , Jean-Luc Jansens , Victor Duysens , Paulus G. Adams , Paulus Van Venrooij , Markus J. C. Lazeroms , Fredric W. Lindemans
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： Certain aspects of the disclosure pertain to methods and apparatus for providing positive fixation of medical components to a portion of incised pericardial tissue. Accordingly, a resilient member protrudes through an incision in the pericardium and produces a positive biasing force to adjacent pericardial tissue against a side surface of an attached body structure. The resilient member can optionally be compressed during implantation and then relaxed to thereafter provide the positive biasing force. Diverse medical components can thus be safely and reliably chronically deployed into the pericardial space, including without limitation, cardiac sensing/pacing, defibrillation and/or cardioversion electrodes, mechanical and/or metabolic sensors and the like. More than one body structure can be linked to a single medical electrical lead and the medical components can couple within and/or upon a portion of the body structure, the resilient member, and the lead in myriad configurations.
摘要翻译：本公开的某些方面涉及用于向切开的心包组织的一部分提供医疗部件的正面固定的方法和装置。因此，弹性构件通过心包中的切口突出，并且相对于附接体结构的侧表面产生相邻心包组织的正偏置力。弹性构件可以可选地在植入期间被压缩，然后松弛，之后提供正的偏压力。因此，不同的医疗部件可以安全可靠地长期地部署到心包空间中，包括但不限于心脏感测/起搏，除颤和/或心脏复律电极，机械和/或代谢传感器等。多个主体结构可以连接到单个医疗电引线，并且医疗部件可以在各种构造中联接在身体结构，弹性构件和引线的一部分内和/或之内。

9. 发明授权

US06434431B1 Intramuscular medical electrical lead with fixation member 有权
标题翻译：具有固定部件的肌内医用电线
公开(公告)号：US06434431B1
公开(公告)日：2002-08-13
申请号：US09487787
申请日：2000-01-20
申请人： Antoine Camps , Victor Duysens , Martin T. Gerber
发明人： Antoine Camps , Victor Duysens , Martin T. Gerber
IPC分类号： A61N105
CPC分类号： A61N1/05 , A61N1/059
摘要： The present invention relates to an intramuscular medical electrical lead, a system for providing electrical stimulation or sensing using such a lead, and methods of implanting, making and using same. The lead includes at least a first fixation member disposed distally or proximally from a sensing or stimulating electrode, and may further include a second fixation member disposed at the opposite end of the electrode form the first fixation member. The fixation members permit the electrode to be reliably and fixedly secured within a patient's muscle tissue at a desired site, and to remain so secured for a predetermined suitable period of time.
摘要翻译：本发明涉及一种肌肉内医用电引线，用于提供使用这种引线的电刺激或感测的系统，以及植入，制造和使用它们的方法。引线包括至少一个从感测或刺激电极远端或近侧设置的第一固定构件，并且还可以包括设置在电极的相对端的第二固定构件，形成第一固定构件。固定构件允许电极可靠地且牢固地固定在患者的肌肉组织中在期望的位置处，并且保持如此固定预定的合适的时间段。

10. 发明申请

US20070255376A1 Pericardium Fixation Concepts of Epicardium Pacing Leads and Tools 有权
标题翻译：心包起搏导联和工具的心包固定概念
公开(公告)号：US20070255376A1
公开(公告)日：2007-11-01
申请号：US11380234
申请日：2006-04-26
申请人： Koen Michels , Jean-Luc Jansens , Victor Duysens , Paulus Adams , Paulus Van Venrooij , Markus Lazeroms , Fredric Lindemans
发明人： Koen Michels , Jean-Luc Jansens , Victor Duysens , Paulus Adams , Paulus Van Venrooij , Markus Lazeroms , Fredric Lindemans
IPC分类号： A61N1/00
CPC分类号： A61N1/0587
摘要： Certain aspects of the disclosure pertain to methods and apparatus for providing positive fixation of medical components to a portion of incised pericardial tissue. Accordingly, a resilient member protrudes through an incision in the pericardium and produces a positive biasing force to adjacent pericardial tissue against a side surface of an attached body structure. The resilient member can optionally be compressed during implantation and then relaxed to thereafter provide the positive biasing force. Diverse medical components can thus be safely and reliably chronically deployed into the pericardial space, including without limitation, cardiac sensing/pacing, defibrillation and/or cardioversion electrodes, mechanical and/or metabolic sensors and the like. More than one body structure can be linked to a single medical electrical lead and the medical components can couple within and/or upon a portion of the body structure, the resilient member, and the lead in myriad configurations.
摘要翻译：本公开的某些方面涉及用于向切开的心包组织的一部分提供医疗部件的正面固定的方法和装置。因此，弹性构件通过心包中的切口突出，并且相对于附接体结构的侧表面产生相邻心包组织的正偏置力。弹性构件可以可选地在植入期间被压缩，然后松弛，之后提供正的偏压力。因此，不同的医疗部件可以安全可靠地长期地部署到心包空间中，包括但不限于心脏感测/起搏，除颤和/或心脏复律电极，机械和/或代谢传感器等。多个主体结构可以连接到单个医疗电引线，并且医疗部件可以在各种构造中联接在身体结构，弹性构件和引线的一部分内和/或之内。

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