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    • 6. 发明授权
    • Multi-location posture sensing
    • 多位置姿态检测
    • US08788055B2
    • 2014-07-22
    • US11800653
    • 2007-05-07
    • Martin T. GerberJohn C. Rondoni
    • Martin T. GerberJohn C. Rondoni
    • A61N1/36A61N1/05
    • A61N1/36135A61N1/0551A61N1/36514A61N1/36535A61N1/36542
    • Techniques for controlling therapy delivery based on the relative orientation and/or motion of a device accelerometer and a lead accelerometer are described. In one embodiment, a therapy system includes an electrical stimulator and a lead. The electrical stimulator comprises a processor that controls delivery of a therapy to a target stimulation site in a patient and a device accelerometer coupled to the electrical stimulator. The lead is coupled to the electrical stimulator to deliver the therapy from the electrical stimulator to the target stimulation site in the patient, and includes a lead accelerometer. The processor compares signals from the accelerometers, and controls delivery of the therapy to the patient based on the comparison. In this manner, the processor may adjust stimulation to, for example, address movement of electrodes relative to target tissue when a patient changes postures.
    • 描述了基于设备加速度计和线加速度计的相对取向和/或运动来控制治疗递送的技术。 在一个实施例中,治疗系统包括电刺激器和引线。 电刺激器包括处理器,其控制对患者的目标刺激部位的治疗传递和耦合到电刺激器的装置加速度计。 引线耦合到电刺激器以将治疗从电刺激器传递到患者中的目标刺激部位,并且包括引线加速度计。 处理器比较来自加速度计的信号,并且基于比较来控制对患者的治疗传递。 以这种方式,当患者改变姿势时,处理器可以将刺激调整为例如电极相对于靶组织的地址移动。
    • 8. 发明授权
    • Therapy program modification
    • 治疗方案修改
    • US08554331B2
    • 2013-10-08
    • US12989763
    • 2009-01-23
    • Martin T. GerberJohn C. Rondoni
    • Martin T. GerberJohn C. Rondoni
    • A61N1/00
    • A61N1/36071A61N1/08A61N1/36007
    • A therapy program may be generated based on an algorithmic model of a baseline therapy field, which may represent a therapy field resulting from therapy delivery via the first therapy system based on a first therapy program. A second therapy program that controls therapy delivery by a second therapy system may be generated based on the baseline therapy field model. For example, therapy parameter values of the second therapy program may be selected to maintain at least one field characteristic of the baseline therapy field model. In some examples, the second therapy system may result from a hardware modification to the first therapy system. In other examples, the first and second therapy systems may be associated with different patients. For example, the baseline therapy field model may be an efficacious therapy field for a patient class, and a second therapy program may be generated for a patient in the class.
    • 可以基于基线治疗领域的算法模型来产生治疗程序,其可以代表由基于第一治疗程序的经由第一治疗系统的治疗递送产生的治疗领域。 可以基于基线治疗场模型来产生控制第二疗法系统治疗传递的第二疗法程序。 例如,可以选择第二治疗程序的治疗参数值以保持基线治疗场模型的至少一个场特征。 在一些示例中,第二治疗系统可能由对第一治疗系统的硬件修改而产生。 在其他实施例中,第一和第二治疗系统可以与不同的患者相关联。 例如,基线治疗场模型可以是患者类别的有效治疗领域,并且可以为该类别中的患者生成第二治疗程序。
    • 9. 发明授权
    • Flexible tube sensor for sensing urinary sphincter pressure
    • 柔性管传感器用于感测尿路括约肌压力
    • US08478411B2
    • 2013-07-02
    • US13279826
    • 2011-10-24
    • Martin T. GerberKeith A. Miesel
    • Martin T. GerberKeith A. Miesel
    • A61N1/00
    • A61N1/36007A61B5/0031A61B5/076A61B5/202A61B5/205A61B5/6882
    • The disclosure describes a therapeutic sphincter control system with a fluid tube pressure sensor. The system senses sphincter pressure and sends the information to a stimulator that is capable of stimulation therapy to control sphincter contractility, thus reducing unwanted urinary incontinence. Measuring sphincter pressure is accomplished through the use of a fluid-filled tube placed through the sphincter and attached to a module implanted within the bladder. Pressure within the tube is transduced to generate an electrical signal that is sent wirelessly to an implanted stimulator connected to a lead positioned near pelvic floor nerves. An external device may be used to wirelessly send information to the implanted stimulator and inhibit stimulation in order for the patient to empty the bladder. Pressure information and stimulation information may be recorded and reviewed for continued patient monitoring. In addition, the system may only include the pressure sensor to monitor patient pressure information.
    • 本公开描述了具有流体管压力传感器的治疗括约肌控制系统。 该系统感测括约肌压力,并将信息发送到能够刺激治疗的刺激器以控制括约肌收缩力,从而减少不必要的尿失禁。 测量括约肌压力是通过使用通过括约肌放置的流体填充管并附接到植入膀胱内的模块来实现的。 所述管内的压力被传导以产生电信号,所述电信号被无线地发送到连接到靠近盆底神经的引线的植入刺激器。 外部设备可以用于向植入的刺激器无线地发送信息并抑制刺激以使患者清空膀胱。 可以记录和审查压力信息和刺激信息以进行持续的患者监测。 另外,该系统可能只包括用于监测患者压力信息的压力传感器。
    • 10. 发明授权
    • Electrical stimulation to alleviate chronic pelvic pain
    • 电刺激缓解慢性盆腔疼痛
    • US08423146B2
    • 2013-04-16
    • US12861165
    • 2010-08-23
    • Jonathon E. GiftakisMartin T. Gerber
    • Jonathon E. GiftakisMartin T. Gerber
    • A61N1/34
    • A61N1/36071A61N1/0551A61N1/0556A61N1/36007
    • The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.
    • 本公开描述了一种将电刺激施加到患者的基因原经神经的生殖器神经或生殖器分支的方法和系统。 该系统包括电刺激器,其应用电刺激以缓解盆腔疼痛。 该系统可以对男性或女性进行电刺激用于骨盆疼痛。 电刺激器可以包括各种类型的电极,诸如袖带电极,电极引线和微刺激器,其植入在靠近单个或两个基因视网膜神经和患者的单个或两个基因颅神经的生殖分支的不同位置处。 当植入到生殖器神经分支附近时,电极可以在生殖神经分支附近植入。 在男性患者中,刺激可以靠近精子束递送,精索包含生殖器神经分支的一部分。