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    • 2. 发明授权
    • 1,3,4-Thiadiazolyloxyphenylureas
    • 1,3,4-噻二唑基氧基苯基脲
    • US4364769A
    • 1982-12-21
    • US166679
    • 1980-07-07
    • Georg PissiotasOtto RohrHaukur Kristinsson
    • Georg PissiotasOtto RohrHaukur Kristinsson
    • A01N47/30A01N47/32A01N47/38C07D285/12C07D285/125C07D285/13A01N47/28
    • C07D285/13A01N47/30A01N47/32A01N47/38C07D285/125
    • The invention relates to novel 1,3,4-thiadiazolyloxyphenylureas which possess herbicidal properties and which have good selectivity in different crops of cultivated plants. The novel phenylureas have the general formula I ##STR1## wherein X is hydrogen, halogen or trifluoromethyl,Y is hydrogen, C.sub.1 -C.sub.6 alkyl which can be interrupted by oxygen or substituted by halogen or cyano; C.sub.3 -C.sub.6 cycloalkyl, cyclopropylmethyl, phenyl which is unsubstituted or substituted by chlorine or C.sub.1 -C.sub.4 alkyl; or is C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylsulfinyl or C.sub.1 -C.sub.4 alkylsulfonyl, or a sulfamoyl group --SO.sub.2 NR.sub.2 R.sub.3,R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl,R.sub.2 is hydrogen, C.sub.1 -C.sub.6 alkyl which can be interrupted by oxygen or substituted by halogen or cyano, or is C.sub.3 -C.sub.6 alkenyl or C.sub.3 -C.sub.6 alkynyl, or C.sub.3 -C.sub.6 cycloalkyl, has the same meaning as R.sub.2 or is C.sub.1 -C.sub.6 alkoxy, orR.sub.2 and R.sub.3, together with the nitrogen atom to which they are attached, can also form a 5- or 6-membered heterocyclic ring system which can contain an additional oxygen or sulfur atom or an imino group which is unsubstituted or substituted by C.sub.1 -C.sub.3 alkyl.
    • 本发明涉及具有除草性能并且在不同作物栽培植物中具有良好选择性的新型1,3,4-噻二唑基氧基苯基脲。 新颖的苯脲具有通式I其中X为氢,卤素或三氟甲基,Y为氢,可被氧中断或被卤素或氰基取代的C 1 -C 6烷基; C3-C6环烷基,环丙基甲基,未取代或被氯或C1-C4烷基取代的苯基; 或者是C1-C4烷硫基,C1-C4烷氧基,C1-C4烷基亚磺酰基或C1-C4烷基磺酰基,或氨磺酰基-SO2NR2R3,R1是氢或C1-C4烷基,R2是氢,可被中断的C1-C6烷基 或被C 3 -C 6炔基或C 3 -C 6环烷基取代,或具有与R 2相同的含义或C 1 -C 6烷氧基,或者R 2和R 3与氮原子一起 它们还可以形成可以含有另外的氧或硫原子的5或6元杂环体系或未被取代或被C 1 -C 3烷基取代的亚氨基。
    • 4. 发明授权
    • Sulfonyl carbonoimidates
    • 磺酰基碳酰亚胺酯
    • US4629802A
    • 1986-12-16
    • US707358
    • 1985-03-01
    • Haukur KristinssonWerner Topfl
    • Haukur KristinssonWerner Topfl
    • C07D251/46A01N47/36A01N47/42C07C67/00C07C301/00C07C303/38C07C303/40C07C311/63C07D239/42C07D239/47C07D251/16C07D521/00C07C119/20
    • C07D521/00
    • A novel process for producing sulfonylureas of the formula I having a herbicidal action and an action regulating plant growth ##STR1## wherein A is an unsubstituted or substituted phenyl, naphthyl, furan, thiophene or pyridine group, E is a nitrogen atom or the methine group, R.sub.a is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -haloalkyl, C.sub.1 -C.sub.5 -alkoxy, C.sub.1 -C.sub.5 -haloalkoxy, C.sub.1 -C.sub.5 -alkylthio or C.sub.2 -C.sub.10 -alkoxyalkoxy, and R.sub.b is the same as R.sub.a or is an unsubstituted or substituted amino group, and salts thereof, which process comprises firstly condensing an imidocarbonic acid ester with a sulfonyl chloride of the formula II to the sulfonylimidocarbonic acid diester of the formula IV ##STR2## wherein R is an alkyl group, and reacting this in an ethereal solvent in the presence of sodium hydride or potassium tertbutylate with a 2-aminopyrimidine or 2-amino-1,3,5-triazine of the formula V, and finally reacting the formed sulfonylisourea of the formula VI in an organic solvent with hydrochloric acid to obtain the sulfonylurea of the formula I, and isolating this as such or as a salt; ##STR3## The sulfonylimidocarbonic acid diesters of the formula IV and certain sulfonylisoureas of the formula VI, required as intermediates, are novel compounds. The process has the advantage that no sulfonamides are needed as intermediates.
    • 一种制备具有除草作用和调节植物生长作用的式I的磺酰脲的新方法,其中A是未取代或取代的苯基,萘基,呋喃,噻吩或吡啶基,E是氮原子或 次甲基,R a为氢,卤素,C 1 -C 5 - 烷基,C 1 -C 5 - 卤代烷基,C 1 -C 5 - 烷氧基,C 1 -C 5 - 卤代烷氧基,C 1 -C 5 - 烷硫基或C 2 -C 10 - 烷氧基烷氧基,Rb为 与R a相同或为未取代或取代的氨基及其盐,该方法包括首先将亚氨基碳酸酯与式II的磺酰氯缩合成式IV的磺酰亚胺基碳酸二酯其中R是烷基 并将其在惰性溶剂中,在氢化钠或叔丁醇钾存在下与式V的2-氨基嘧啶或2-氨基-1,3,5-三嗪反应,最后使形成的式VI的磺酰基异脲 在有盐酸的有机溶剂中 在式I的磺酰脲中,并将其分离为盐或盐; 作为中间体,式IV的磺酰亚胺基碳酸二酯和式VI的某些磺酰基异脲是新化合物。 该方法的优点是不需要磺酰胺作为中间体。
    • 6. 发明授权
    • Process for the preparation of aminotriazine derivatives
    • 氨基三嗪衍生物的制备方法
    • US5561230A
    • 1996-10-01
    • US460342
    • 1995-06-02
    • Ernst BerigerHaukur Kristinsson
    • Ernst BerigerHaukur Kristinsson
    • C07D253/06C07D271/10C07D271/113C07D401/12C07D413/06
    • C07D253/06C07D271/113C07D401/12C07D413/06
    • The invention relates to a process for the preparation of a compound of formula ##STR1## useful as intermediate for the preparation of pesticides, wherein R is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkyl substituted by from 1 to 10 halogen atoms or by from 1 to 3 radicals selected from the group consisting of C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio and phenyl, phenyl or phenyl substituted by from 1 to 3 radicals selected from the group consisting of halogen, methyl, ethyl, methoxy, methylthio and nitro, which comprises reacting with hydrazine hydrate a compound of formula ##STR2## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkyl substituted by from 1 to 9 chlorine atoms, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio, C.sub.1 -C.sub.3 alkylsulfinyl, C.sub.1 -C.sub.3 alkylsulfonyl, phenyl, phenyl substituted by from 1 to 3 radicals selected from the group consisting of halogen, methyl, ethyl, methoxy, methylthio and nitro, or pyridyl, and subjecting to hydrolysis the resulting compound of formula ##STR3##
    • 本发明涉及制备式(I)化合物的方法,其可用作制备农药的中间体,其中R是氢,C 1 -C 6烷基,C 3 -C 6环烷基,被1至 10个卤素原子或1至3个选自C 1 -C 3烷氧基,C 1 -C 3烷硫基和苯基的基团,苯基或被1至3个选自卤素,甲基,乙基,甲氧基, 甲硫基和硝基,其包括与水合肼反应其中R 1是氢,C 1 -C 4烷基,C 3 -C 6环烷基,被1至9个氯原子取代的C 1 -C 4烷基,C 1 -C 3烷氧基,C 1 C 3烷硫基,C 1 -C 3烷基亚磺酰基,C 1 -C 3烷基磺酰基,苯基,被1至3个选自卤素,甲基,乙基,甲氧基,甲硫基和硝基或吡啶基的基取代的苯基,并将所得化合物 公式(III)