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1. 发明授权

US06395287B1 Lotions containing vitamin D3 derivatives 失效
公开(公告)号：US06395287B1
公开(公告)日：2002-05-28
申请号：US09988367
申请日：2001-11-19
申请人： Eiichi Miyauchi , Yasuyuki Sakai , Keiko Sano
发明人： Eiichi Miyauchi , Yasuyuki Sakai , Keiko Sano
IPC分类号： A61K748
CPC分类号： A61K9/0014 , A61K9/08 , A61K31/593 , A61K47/10 , A61K47/26
摘要： The present invention aims to provide a lotion stably maintaining maxacalcitol and having excellent percutaneous absorption. The present invention provides lotions comprising maxacalcitol as an active ingredient and a nonionic surfactant as an additive, as well as lotions which further contains a polyhydric alcohol and a solubilizer as additives besides a nonionic surfactant.

2. 发明授权

US06372233B1 Lotions containing vitamin D3 derivatives 失效
公开(公告)号：US06372233B1
公开(公告)日：2002-04-16
申请号：US09555815
申请日：2000-06-05
申请人： Eiichi Miyauchi , Yasuyuki Sakai , Keiko Sano
发明人： Eiichi Miyauchi , Yasuyuki Sakai , Keiko Sano
IPC分类号： A61K700
CPC分类号： A61K9/0014 , A61K9/08 , A61K31/593 , A61K47/10 , A61K47/26
摘要： The present invention aims to provide a lotion stably maintaining maxacalcitol and having excellent percutaneous absorption. The present invention provides lotions comprising maxacalcitol as an active ingredient and a nonionic surfactant as an additive, as well as lotions which further contains a polyhydric alcohol and a solubilizer as additives besides a nonionic surfactant.

3. 发明授权

US08659920B2 Switching device provided with a flowing restriction element 有权
标题翻译：具有流动限制元件的开关装置
公开(公告)号：US08659920B2
公开(公告)日：2014-02-25
申请号：US13314499
申请日：2011-12-08
申请人： Nobuhisa Yamaguchi , Yasuyuki Sakai
发明人： Nobuhisa Yamaguchi , Yasuyuki Sakai
IPC分类号： H02H7/122
CPC分类号： H02M1/34 , H01L2224/48091 , H01L2224/73265 , H01L2924/1301 , H01L2924/1305 , H01L2924/13055 , H01L2924/30107 , H02M2001/348 , H01L2924/00014 , H01L2924/00
摘要： A switching device includes a flowing restriction element, a conductor and a snubber resistor. The flowing restriction element has an opening and closing function to open and close a flowing path of an electric current. The conductor is connected to the flowing restriction element. The snubber resistor is connected to the flowing restriction element and constitutes a snubber circuit. The snubber resistor is disposed along the conductor.
摘要翻译：开关装置包括流动限制元件，导体和缓冲电阻器。流动限制元件具有打开和关闭电流流动通道的打开和关闭功能。导体连接到流动的限制元件。缓冲电阻器连接到流动限制元件并构成缓冲电路。缓冲电阻器沿着导体设置。

4. 发明申请

US20110136234A1 CELL CULTURE SUBSTRATE AND ITS PRODUCTION METHOD 有权
标题翻译：细胞培养基质及其生产方法
公开(公告)号：US20110136234A1
公开(公告)日：2011-06-09
申请号：US13020193
申请日：2011-02-03
申请人： Shin OHYA , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
发明人： Shin OHYA , Takashi Inoue , Takatoki Yamamoto , Teruo Fujii , Yasuyuki Sakai , Masaki Nishikawa , Hitomi Sakai , Hirosuke Naruto
IPC分类号： C12N5/07 , C12N5/0735
CPC分类号： C12N5/0068 , C08G2261/3424 , C08L65/04 , C12N2533/30
摘要： A cell culture substrate which is durable and which can be readily produced in commercial scale at a low cost, and its production method are provided. The cell culture substrate comprises a substrate and a layer formed by surface modification, which comprises a polymer containing amino group produced by reacting a polymer represented by the following formula (II): (wherein n is 0 or a positive integer, and m is a positive integer, the n and m representing degree of polymerization) formed by chemical vapor deposition of formyl[2.2]paracyclophane represented by the following formula (I): (wherein k is 0 or 1) with a polymer having at least one amino group (—NH2) capable of forming Schiff base in its monomer. The production method of the cell culture substrate comprises the step of synthesizing such polymer on the substrate.
摘要翻译：提供耐久性且能够以低成本容易地以商业规模生产的细胞培养基材及其制造方法。细胞培养基材包括基材和通过表面改性形成的层，其包含通过使由下式（II）表示的聚合物反应而生成的含氨基的聚合物：（其中n为0或正整数，m为正整数，代表聚合度的n和m）通过化学气相沉积由下式（I）表示的甲酰基[2.2]对环烷烃形成：（其中k为0或1）与具有至少一个氨基的聚合物 -NH2）能够在其单体中形成席夫碱。细胞培养基质的制造方法包括在基材上合成这样的聚合物的工序。

5. 发明授权

US5140141A Bar-code reader with reading zone indicator 失效
标题翻译：具有阅读区指示器的条码阅读器
公开(公告)号：US5140141A
公开(公告)日：1992-08-18
申请号：US581217
申请日：1990-09-12
申请人： Masahiro Inagaki , Osamu Asai , Yasuyuki Sakai
发明人： Masahiro Inagaki , Osamu Asai , Yasuyuki Sakai
IPC分类号： G06K7/10
CPC分类号： G06K7/10
摘要： A bar-code reader for reading bar codes on articles or commodities in supermarkets or retail stores has a scanning unit mounted on a vertically movable support post assembly and including a scanning system which emits a scanning light beam and detects light reflected from a bar code. The bar-code reader includes various indicating members, such as an indicator rod, an indicator ring, an arrow mark, a pattern mark, and a colored sheet, for indicating to the operator a direction, a position, and an area or zone in which to pass an article with a bar code in order for the bar code to be successully read by the scanning system.
摘要翻译：用于读取超市或零售商店中的物品或商品上的条形码的条形码读取器具有安装在可垂直移动的支撑柱组件上的扫描单元，并且包括发射扫描光束并检测从条形码反射的光的扫描系统。条形码阅读器包括诸如指示杆，指示器环，箭头标记，图案标记和着色纸的各种指示构件，用于向操作者指示方向，位置和区域或区域通过条形码传递文章，以便条形码被扫描系统顺利读取。

6. 发明授权

US4005576A Internal combustion engine exhaust manifold with cylindrical built-in catalyst container 失效
标题翻译：具有圆柱形内置催化剂容器的内燃机排气歧管
公开(公告)号：US4005576A
公开(公告)日：1977-02-01
申请号：US569558
申请日：1975-04-18
申请人： Hidetaka Nohira , Hironori Bessho , Yasuyuki Sakai
发明人： Hidetaka Nohira , Hironori Bessho , Yasuyuki Sakai
IPC分类号： F01N3/28 , F01N3/34 , F01N13/10 , F01N3/15
CPC分类号： F01N13/10 , F01N3/2846 , F01N3/34 , F01N2270/04 , F01N2330/08 , F01N2430/06 , Y02T10/20
摘要： An internal combustion engine exhaust manifold with cylindrical built-in catalyst container which comprises cylindrical inner and outer cylinders and annular lids fitting at opposite ends thereof and is filled with a catalyst suitable for cleaning the engine exhaust.An exhaust gas cleaning device using the exhaust manifold comprises an oxygen concentration sensor located in the exhaust gas flow and an electronic fuel injector for performing feedback control in accordance with a signal from the oxygen concentration sensor.
摘要翻译：具有圆柱形内置催化剂容器的内燃机排气歧管，其包括圆柱形内外圆筒和安装在其相对端的环形盖，并且填充有适于清洁发动机排气的催化剂。

7. 发明申请

US20130179691A1 SIGNATURE GENERATION APPARATUS, SIGNATURE GENERATION METHOD, AND STORAGE MEDIUM 有权
标题翻译：签名生成装置，签名生成方法和存储介质
公开(公告)号：US20130179691A1
公开(公告)日：2013-07-11
申请号：US13824577
申请日：2010-12-24
申请人： Yusuke Naito , Yasuyuki Sakai
发明人： Yusuke Naito , Yasuyuki Sakai
IPC分类号： H04L9/32
CPC分类号： H04L9/3252
摘要： e and n are public information and d is private information. An electronic signature is generated based on a calculated value of e×d mod n. A signature generation apparatus 100 includes a random number generation unit 103, a first calculation unit 111, a second calculation unit 112, and a signature generation unit 121. The random number generation unit 103 generates a random number r. The first calculation unit 111 calculates s1=r×n. The second calculation unit 112 calculates s2=s1+e. The signature generation unit 121 calculates s3=s2×d mod n and outputs s3 as the calculated value of e×d mod n. The signature generation apparatus 100 can thereby generate the above electronic signature securely against differential power attacks.
摘要翻译： e和n是公共信息，d是私人信息。基于e×d mod n的计算值生成电子签名。签名生成装置100包括随机数生成单元103，第一计算单元111，第二计算单元112和签名生成单元121.随机数生成单元103生成随机数r。第一计算单元111计算s1 = r×n。第二计算单元112计算s2 = s1 + e。签名生成部121计算s3 = s2×d mod n，并输出s3作为e×d mod n的计算值。因此，签名生成装置100可以稳定地生成上述电子签名来抵抗差分电力攻击。

8. 发明授权

US08328293B2 Shield machine 有权
标题翻译：盾牌机
公开(公告)号：US08328293B2
公开(公告)日：2012-12-11
申请号：US12524550
申请日：2007-01-26
申请人： Yasunori Kondo , Hiroyoshi Iwata , Yasuyuki Sakai , Makoto Oda , Tooru Niihara , Isao Makiuchi , Kunihiro Nagamori , Katsumi Inomata , Hidekazu Anai
发明人： Yasunori Kondo , Hiroyoshi Iwata , Yasuyuki Sakai , Makoto Oda , Tooru Niihara , Isao Makiuchi , Kunihiro Nagamori , Katsumi Inomata , Hidekazu Anai
IPC分类号： E21D9/87
CPC分类号： E21D9/117 , E21D9/0879
摘要： A shield machine including an excavator capable of excavating tunnels of various cross-sectional shapes, the excavator including: a rotary drum supported at a front end side portion of a shield machine main body to be rotatable around a first center axis; a cutter supporting frame supported by the rotary drum to be rotatable around a second center axis; a rotary cutter head supported by the cutter supporting frame to be rotatable around a third center axis and including a plurality of cutter bits on a surface thereof; a rotary auxiliary cutter head supported by the rotary drum to be rotatable around a fourth center axis; and first, third, and fourth rotating mechanisms, and a swinging drive mechanism configured to respectively cause the rotary drum, the rotary cutter head, the rotary auxiliary cutter head, and the cutter supporting frame to independently rotate.
摘要翻译： 1.一种盾构机，其特征在于，包括能够挖掘各种截面形状的挖掘机的挖掘机，所述挖掘机包括：旋转滚筒，其支撑在所述盾构机主体的前端侧部分，能够围绕第一中心轴线旋转; 由所述旋转滚筒支撑以能够围绕第二中心轴线旋转的切割器支撑框架; 旋转刀头，其由所述刀具支撑框架支撑，以围绕第三中心轴线旋转并且在其表面上包括多个切割刀头; 旋转辅助切割头，其由所述旋转滚筒支撑以围绕第四中心轴线旋转; 以及分别使旋转滚筒，旋转切割头，旋转辅助切割头和切割器支撑框架分别旋转的摆动驱动机构和第一，第三和第四旋转机构。

9. 发明授权

US08187891B2 Methods for detection and determination of vitamin C by luminescence 有权
标题翻译：通过发光检测和测定维生素C的方法
公开(公告)号：US08187891B2
公开(公告)日：2012-05-29
申请号：US12726294
申请日：2010-03-17
申请人： Kazuyuki Ishii , Kensuke Kubo , Kikuo Komori , Yasuyuki Sakai
发明人： Kazuyuki Ishii , Kensuke Kubo , Kikuo Komori , Yasuyuki Sakai
IPC分类号： G01N33/00 , G01N21/64
CPC分类号： G01N33/82 , A61K49/0036 , A61K49/0084 , Y10T436/142222 , Y10T436/20 , Y10T436/200833 , Y10T436/203332
摘要： The present invention provides a method for detection or determination of vitamin C by luminescence that employs a redox-responsive fluorogenic probe consisting of porphyrin or phthalocyanine with a nitroxide radical(s), or that employs a liposome preparation comprising the said redox-responsive fluorogenic probe. The present method can overcome the problems of prior art methods, and in particular, are applicable for bioimaging to allow elucidation of the behavior of vitamin C in vivo.
摘要翻译：本发明提供了一种通过发光检测或测定维生素C的方法，该方法使用由卟啉或酞菁与氮氧自由基组成的氧化还原反应性荧光探针，或采用含有所述氧化还原反应性荧光探针的脂质体制剂。本发明的方法可以克服现有技术方法的问题，特别是适用于生物成像以允许在体内阐明维生素C的行为。

10. 发明授权

US07231960B2 Cooler for cooling both sides of semiconductor device 有权
标题翻译：冷却器用于冷却半导体器件的两侧
公开(公告)号：US07231960B2
公开(公告)日：2007-06-19
申请号：US10733472
申请日：2003-12-12
申请人： Yasuyuki Sakai
发明人： Yasuyuki Sakai
IPC分类号： F28F9/013
CPC分类号： F28F3/12 , H01L23/473 , H01L2924/0002 , H01L2924/00
摘要： An object of the present invention is to provide a cooler for cooling both sides (top and bottom surfaces) of a semiconductor device, wherein the variation of pressing force on flat cooling tubes holding a semiconductor device is reduced, thereby uniformly dissipating the heat generated by the semiconductor device. When the holding plates press the flat cooling tubes and semiconductor modules by tightening the nut, the dimensional tolerances in the stacking direction are absorbed by the deformable portions in the inlet and outlet headers. A spacer may be employed inside the flat cooling tubes in order to suppress the deformation of the flat cooling tubes along the stacking direction.
摘要翻译：本发明的目的是提供一种用于冷却半导体器件的两侧（顶表面和底表面）的冷却器，其中，保持半导体器件的平坦冷却管上的按压力的变化减小，从而均匀地散发由半导体器件。当保持板通过拧紧螺母挤压扁平冷却管和半导体模块时，层叠方向上的尺寸公差被入口和出口集管中的可变形部分吸收。为了抑制扁平冷却管沿层叠方向的变形，可以在平面冷却管内使用间隔件。

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