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1. 发明授权

US6077713A Method and apparatus for extracting liquid samples from a closed container 失效
标题翻译：从密闭容器中提取液体样品的方法和装置
公开(公告)号：US6077713A
公开(公告)日：2000-06-20
申请号：US108018
申请日：1998-06-30
申请人： William David Dunfee , Edward Stephen Kaminski , John Charles Mazza , Kerry Lynn Miller , Jeffery Kenneth Parmer , Paul John Zuk
发明人： William David Dunfee , Edward Stephen Kaminski , John Charles Mazza , Kerry Lynn Miller , Jeffery Kenneth Parmer , Paul John Zuk
IPC分类号： G01N1/10 , G01N1/00 , G01N35/10
CPC分类号： G01N35/1079 , Y10T436/11 , Y10T436/2575
摘要： Extracting a quantity of liquid from a closed container by driving a cannula having a passage the length of the cannula and a groove a partial length of the cannula through the closure of the container until the groove establishes communication between a pressurized chamber and the container, thereby forcing liquid from the tube through the passage.
摘要翻译：通过驱动具有套管长度的通道的套管和套管的部分长度通过容器的封闭件直到槽形成加压室和容器之间的连通来从密封容器中提取一定量的液体，由此迫使液体从管通过通道。

2. 发明授权

US08969098B2 Methods and systems providing reagent mixing 有权
标题翻译：提供试剂混合的方法和系统
公开(公告)号：US08969098B2
公开(公告)日：2015-03-03
申请号：US13636944
申请日：2011-04-05
申请人： Edward Stephen Kaminski
发明人： Edward Stephen Kaminski
IPC分类号： G01N35/10 , B01F11/00 , G01N35/00
CPC分类号： G01N35/10 , B01F11/0074 , G01N2035/00544 , G01N2035/1058 , Y10T436/25 , Y10T436/2575
摘要： Disclosed are methods and systems adapted to provide mixing of a liquid reagent in an automated clinical analyzer. The methods include aspirating an air separator (e.g., an air slug) into the interior of a probe. A relatively small volume of reagent liquid is also aspirated into the probe adjacent to the air separator; the volume of liquid reagent being entirely contained within the probe. The volume of liquid reagent may be repeatedly aspirated and dispensed at a relatively high frequency to accomplish reagent mixing in the reagent container. Improved sample and reagent mixing may be promoted using a similar method. Systems carrying out the methods are provided, as are other aspects.
摘要翻译：公开了适于在自动临床分析仪中提供液体试剂的混合的方法和系统。这些方法包括将空气分离器（例如空气塞）吸入探针的内部。相对较小体积的试剂液体也被吸入与空气分离器相邻的探针中; 液体试剂的体积完全包含在探针内。液体试剂的体积可以以相对较高的频率重复抽吸和分配，以在试剂容器中实现试剂混合。可以使用类似的方法来促进改进的样品和试剂混合。提供了执行方法的系统，以及其他方面。

3. 发明申请

US20130017621A1 METHODS AND SYSTEMS PROVIDING REAGENT MIXING 有权
标题翻译：提供试剂混合的方法和系统
公开(公告)号：US20130017621A1
公开(公告)日：2013-01-17
申请号：US13636944
申请日：2011-04-05
申请人： Edward Stephen Kaminski
发明人： Edward Stephen Kaminski
IPC分类号： G01N1/38
CPC分类号： G01N35/10 , B01F11/0074 , G01N2035/00544 , G01N2035/1058 , Y10T436/25 , Y10T436/2575
摘要： Disclosed are methods and systems adapted to provide mixing of a liquid reagent in an automated clinical analyzer. The methods include aspirating an air separator (e.g., an air slug) into the interior of a probe. A relatively small volume of reagent liquid is also aspirated into the probe adjacent to the air separator; the volume of liquid reagent being entirely contained within the probe. The volume of liquid reagent may be repeatedly aspirated and dispensed at a relatively high frequency to accomplish reagent mixing in the reagent container. Improved sample and reagent mixing may be promoted using a similar method. Systems carrying out the methods are provided, as are other aspects.
摘要翻译：公开了适于在自动临床分析仪中提供液体试剂的混合的方法和系统。这些方法包括将空气分离器（例如空气塞）吸入探针的内部。相对较小体积的试剂液体也被吸入与空气分离器相邻的探针中; 液体试剂的体积完全包含在探针内。液体试剂的体积可以以相对较高的频率重复抽吸和分配，以在试剂容器中实现试剂混合。可以使用类似的方法来促进改进的样品和试剂混合。提供了执行方法的系统，以及其他方面。

4. 发明授权

US06645737B2 Method for maintaining test accuracy within a microbiological test array 失效
标题翻译：在微生物测试阵列中维持测试精度的方法
公开(公告)号：US06645737B2
公开(公告)日：2003-11-11
申请号：US09841029
申请日：2001-04-24
申请人： Edward Francis Farina , Edward Stephen Kaminski , John Charles Mazza , Bruce McLean Gemmell , William David Dunfee
发明人： Edward Francis Farina , Edward Stephen Kaminski , John Charles Mazza , Bruce McLean Gemmell , William David Dunfee
IPC分类号： C12Q118
CPC分类号： C12Q1/18
摘要： A microbiological test array with a plurality of microwells connected by a microchannel to a solution reservoir. Subsequent to filling the microwells, the microchannels are sealed to protect the integrity of the solution in the test microwells.
摘要翻译：具有多个微孔的微生物测试阵列，其通过微通道连接到溶液储存器。在填充微孔之后，密封微通道以保护测试微孔中的溶液的完整性。

5. 发明授权

US06653122B2 Indentification test device in a random access microbiological analyzer 失效
标题翻译：随机存取微生物分析仪中的识别测试装置
公开(公告)号：US06653122B2
公开(公告)日：2003-11-25
申请号：US09841408
申请日：2001-04-24
申请人： Edward Francis Farina , Bruce McLean Gemmell , John Charles Mazza , Michael Taylor McVey , Edward Stephen Kaminski , Antoine Elias Haddad , Peter Louis Gebrian
发明人： Edward Francis Farina , Bruce McLean Gemmell , John Charles Mazza , Michael Taylor McVey , Edward Stephen Kaminski , Antoine Elias Haddad , Peter Louis Gebrian
IPC分类号： C12M134
CPC分类号： B01L3/5085 , B01L7/00 , C12M41/36 , C12M41/48 , G01N35/025 , G01N2035/00148 , G01N2035/1076
摘要： A circular shaped rotor to facilitate automated identification testing of microorganisms in a microbiology analyzer having two circular arrays of microwells downwardly projecting from the top of the rotor connected to a recessed central region by a plurality of microchannels formed in the upper surface and connecting the recessed central portion to the second plurality of microwells; the rotor is further adapted to be rotated by a source of rotational energy and moved throughout the analyzer using troughs formed near its outer diameter.
摘要翻译：一种圆形转子，用于在微生物学分析仪中进行微生物分析仪的自动识别测试，该微生物分析仪具有两个圆形阵列的微孔，从形成在上表面的多个微通道的转子的顶部向下突出，从而连接凹入的中心部分到第二多个微孔; 转子还适于通过旋转能量源旋转，并且在整个分析器中使用在其外径附近形成的槽移动。

6. 发明授权

US06582929B2 Method for minimizing optical interference during antibiotic susceptibility readings in a microbiological analyzer 失效
公开(公告)号：US06582929B2
公开(公告)日：2003-06-24
申请号：US09841392
申请日：2001-04-24
申请人： William David Dunfee , Bruce McLean Gemmell , Edward Stephen Kaminski , John Charles Mazza , Edward Francis Farina , Frank Stephen Krufka
发明人： William David Dunfee , Bruce McLean Gemmell , Edward Stephen Kaminski , John Charles Mazza , Edward Francis Farina , Frank Stephen Krufka
IPC分类号： C12Q118
CPC分类号： G01N21/253 , G01N35/00029 , G01N35/025 , G01N2035/00049 , G01N2035/00148
摘要： Performing antibiotic testing on samples contained in test arrays by orienting the arrays relative to the direction of gravity so that test solution within the microwells is drawn downwards and air within the microwells is forced to the uppermost portion of the test array. Antibiotic testing is conducted using an interrogating beam of radiation passing horizontally through the microwells at locations devoid of air bubbles.

7. 发明授权

US5724142A Method and apparatus for measuring and controlling the volume of a liquid segment in a tube 失效
标题翻译：用于测量和控制管中液体段的体积的方法和装置
公开(公告)号：US5724142A
公开(公告)日：1998-03-03
申请号：US619069
申请日：1996-03-29
申请人： Edward Stephen Kaminski , Paul John Zuk
发明人： Edward Stephen Kaminski , Paul John Zuk
IPC分类号： G01F13/00 , G01F1/708 , G01N21/43 , G01N35/10 , G01B11/28
CPC分类号： G01F1/7086 , G01N21/43 , G01N2035/1025
摘要： A method for measuring or controlling the volume of a liquid segment confined within a tube and having a leading edge and a trailing edge. The tube is exposed to radiation at an angle and radiation refracted from the inner surface of the tube is measured at the leading and trailing edges of the segment while the liquid segment is moving through the tube.
摘要翻译：一种用于测量或控制限制在管内且具有前缘和后缘的液体段的体积的方法。管以一定角度暴露于辐射，并且在液体段移动通过管时，在段的前缘和后缘处测量从管的内表面折射的辐射。

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