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1. 发明申请

US20110166455A1 CATHETER 审中-公开
标题翻译：导管
公开(公告)号：US20110166455A1
公开(公告)日：2011-07-07
申请号：US12684079
申请日：2010-01-07
申请人： Edward H. Cully , Dennis R. Dietz , Curtis J. Franklin , Craig T. Nordhausen , Clyde G. Oakley , Ryan C. Patterson , Jim H. Polenske , Thomas W. Shilling , Thomas L. Tolt
发明人： Edward H. Cully , Dennis R. Dietz , Curtis J. Franklin , Craig T. Nordhausen , Clyde G. Oakley , Ryan C. Patterson , Jim H. Polenske , Thomas W. Shilling , Thomas L. Tolt
IPC分类号： A61B8/14
CPC分类号： A61B8/12 , A61B8/4245 , A61B8/4281 , A61B8/445 , A61B8/4461 , A61B8/4466
摘要： An improved catheter is provided. The catheter may include a deflectable member located at a distal end of the catheter. The deflectable member may comprise an ultrasound transducer array. In embodiments where the deflectable member includes an ultrasound transducer array, the ultrasound transducer array may be operable to image both when aligned with the catheter and when pivoted relative to the catheter. When pivoted relative to the catheter, the ultrasound transducer array may have a field of view distal to the distal end of the catheter. The ultrasound array may be interconnected to a motor to effectuate pivotal reciprocal motion of the ultrasound transducer array such that the catheter may be operable to produce real-time or near real-time three dimensional images.
摘要翻译：提供改进的导管。导管可以包括位于导管的远端的可偏转构件。可偏转构件可以包括超声换能器阵列。在可偏转构件包括超声换能器阵列的实施例中，超声换能器阵列可操作以在与导管对准时以及当相对于导管枢转时成像。当相对于导管枢转时，超声换能器阵列可以具有远离导管远端的视场。超声阵列可以互连到电动机以实现超声换能器阵列的枢转往复运动，使得导管可操作以产生实时或接近实时的三维图像。

2. 发明申请

US20100331956A1 ENDOLUMINAL EXPANSION SYSTEM 有权
标题翻译：内膜扩张系统
公开(公告)号：US20100331956A1
公开(公告)日：2010-12-30
申请号：US12876779
申请日：2010-09-07
申请人： Joseph R. Armstrong , Edward H. Cully , Craig T. Nordhausen , Mark J. Ulm , Michael J. Vonesh
发明人： Joseph R. Armstrong , Edward H. Cully , Craig T. Nordhausen , Mark J. Ulm , Michael J. Vonesh
IPC分类号： A61F2/84
CPC分类号： A61F2/958 , A61F2/95 , A61F2/97 , A61F2002/9511
摘要： An endoprosthesis expansion system having, in combination, a delivery component such as a length of catheter tubing having at its distal end an intermediate sheath component, and an inner tube within the full length of the delivery catheter and intermediate sheath component. The inner tube has a protrusion affixed to its distal end, and an expandable endoprosthesis is fitted in a compacted state about the intermediate sheath, immediately proximal to the protrusion. If the endoprosthesis is a self-expanding endoprosthesis (as is preferred), an exterior constraining sheath is required around the outer surface of the endoprosthesis. Following insertion of the endoprosthesis and delivery system into a body conduit (such as a blood vessel) and transport of the endoprosthesis to the desired site within the body conduit, the endoprosthesis is deployed by axially moving the protrusion against the system, thereby applying a radially directed outward force and causing simultaneous dilatation of the intermediate sheath and disruption of the exterior constraining sheath. Disruption of the exterior constraining sheath, in the case of a self-expanding prosthesis, releases the stored energy in the formerly constrained prosthesis, allowing it to expand and accomplish full deployment against the luminal surface of the body conduit at the desired site.
摘要翻译：一种内置假体扩张系统，其组合具有输送部件，例如一段长度的导管，其远端具有中间护套部件，并且在输送导管和中间护套部件的整个长度内具有内管。内管具有固定在其远端的突起，并且可伸缩的内假体围绕中间护套紧密地装配在紧固突起的近侧。如果内置假体是自扩张的内置假体（如优选的），则需要在内假体的外表面周围的外约束护套。在将内假体和输送系统插入身体导管（例如血管）中并将内假体运送到体导管内的期望部位之后，通过将凸起轴向移动抵靠系统来展开内假体，从而施加径向引导向外的力并引起中间鞘的同时扩张和外部约束鞘的破坏。在自扩张假体的情况下，外部约束护套的破坏释放在先前约束的假体中的储存能量，允许其膨胀并且在所需位置处对体导管的腔表面完全完全展开。

3. 发明授权

US09545300B2 Filament-wound implantable devices 有权
标题翻译：长丝缠绕装置
公开(公告)号：US09545300B2
公开(公告)日：2017-01-17
申请号：US11020867
申请日：2004-12-22
申请人： Edward H. Cully , Joseph A Huppenthal , Craig T. Nordhausen , Michael J. Vonesh
发明人： Edward H. Cully , Joseph A Huppenthal , Craig T. Nordhausen , Michael J. Vonesh
IPC分类号： A61F2/06 , A61F2/07 , A61B17/00 , A61B17/12 , A61F2/01 , A61F2/90 , A61F2/82
CPC分类号： A61F2/07 , A61B17/00234 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12145 , A61B17/12172 , A61B2017/00292 , A61B2017/00526 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61F2/01 , A61F2/82 , A61F2/90 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2002/072 , A61F2230/0006 , A61F2230/005 , A61F2230/0065 , A61F2230/008
摘要： A self-expanding implantable medical device formed from one or more non-interlocking filaments. Stents, stent-grafts, occluder devices, and filters are manufactured from one or more filaments utilizing a non-interlocking crossing pattern.
摘要翻译：由一个或多个非互锁细丝形成的自扩张植入式医疗装置。支架，支架移植物，封堵器装置和过滤器由利用非互锁交叉图案的一根或多根细丝制成。

4. 发明授权

US08177832B2 Endoluminal expansion system 有权
标题翻译：腔内扩张系统
公开(公告)号：US08177832B2
公开(公告)日：2012-05-15
申请号：US12876779
申请日：2010-09-07
申请人： Joseph R. Armstrong , Edward H. Cully , Craig T. Nordhausen , Mark J. Ulm , Michael J. Vonesh
发明人： Joseph R. Armstrong , Edward H. Cully , Craig T. Nordhausen , Mark J. Ulm , Michael J. Vonesh
IPC分类号： A61F2/82
CPC分类号： A61F2/958 , A61F2/95 , A61F2/97 , A61F2002/9511
摘要： An endoprosthesis expansion system having, in combination, a delivery component such as a length of catheter tubing having at its distal end an intermediate sheath component, and an inner tube within the full length of the delivery catheter and intermediate sheath component. The inner tube has a protrusion affixed to its distal end, and an expandable endoprosthesis is fitted in a compacted state about the intermediate sheath, immediately proximal to the protrusion. If the endoprosthesis is a self-expanding endoprosthesis (as is preferred), an exterior constraining sheath is required around the outer surface of the endoprosthesis. Following insertion of the endoprosthesis and delivery system into a body conduit (such as a blood vessel) and transport of the endoprosthesis to the desired site within the body conduit, the endoprosthesis is deployed by axially moving the protrusion against the system, thereby applying a radially directed outward force and causing simultaneous dilatation of the intermediate sheath and disruption of the exterior constraining sheath. Disruption of the exterior constraining sheath, in the case of a self-expanding prosthesis, releases the stored energy in the formerly constrained prosthesis, allowing it to expand and accomplish full deployment against the luminal surface of the body conduit at the desired site.
摘要翻译：一种内置假体扩张系统，其组合具有输送部件，例如一段长度的导管，其远端具有中间护套部件，并且在输送导管和中间护套部件的整个长度内具有内管。内管具有固定在其远端的突起，并且可伸缩的内假体围绕中间护套紧密地装配在紧固突起的近侧。如果内置假体是自扩张的内置假体（如优选的），则需要在内假体的外表面周围的外约束护套。在将内假体和输送系统插入身体导管（例如血管）中并将内假体运送到体导管内的期望部位之后，通过将凸起轴向移动抵靠系统来展开内假体，从而施加径向引导向外的力并引起中间鞘的同时扩张和外部约束鞘的破坏。在自扩张假体的情况下，外部约束护套的破坏释放在先前约束的假体中的储存能量，允许其膨胀并且在所需位置处对体导管的腔表面完全完全展开。

5. 发明授权

US09642693B2 Medical apparatus and method of making the same 有权
公开(公告)号：US09642693B2
公开(公告)日：2017-05-09
申请号：US11735372
申请日：2007-04-13
申请人： Edward H. Cully , James Goepfrich , Joanne Hopmeyer , Edward E. Shaw
发明人： Edward H. Cully , James Goepfrich , Joanne Hopmeyer , Edward E. Shaw
IPC分类号： A61B17/08 , A61F2/04 , A61F5/00
CPC分类号： A61F2/04 , A61F5/0003 , A61F5/0076 , A61F5/0089 , A61F2002/044 , A61F2220/0016
摘要： The invention relates to a medical apparatus including a device used in the treatment of weight loss, obesity and potentially other associated health problems, e.g., type II diabetes. The device is used to impede absorption of nutrients within the gastrointestinal tract, i.e., bypassing a portion of the gastrointestinal tract. The medical apparatus enables implantation of the device using minimally invasive techniques, such a transesophageal approach under visualization. The device may be implanted via a working channel of a medical scope, e.g., an endoscope or in combination with a medical scope.

6. 发明授权

US09463269B2 Anastomotic devices and methods 有权
标题翻译：吻合装置和方法
公开(公告)号：US09463269B2
公开(公告)日：2016-10-11
申请号：US13229540
申请日：2011-09-09
申请人： Edward H. Cully , Jeffrey B. Duncan , Karan B. Sangha
发明人： Edward H. Cully , Jeffrey B. Duncan , Karan B. Sangha
IPC分类号： A61B17/08 , A61M1/36 , A61B17/11 , A61F2/06 , A61F2/07 , A61F2/848 , A61F2/89
CPC分类号： A61M1/3655 , A61B17/08 , A61B17/11 , A61B2017/1135 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2002/075 , A61F2002/8486 , A61F2230/0067 , A61F2230/0069
摘要： Exemplary embodiments comprise AV fistulas and other anastomotic devices for creating new or reinforcing existing side-branch vessels, and/or bridging neighboring vessels together. An exemplary embodiment may comprise a sidewall port, such as a flanged sidewall port, and/or flow frame design, such as a partially bare, flexible stent or a whisk, for purposes of creating a transmural flow. Another exemplary embodiment may comprise a compliant vessel support to aid in the transition from device to vessel and/or vessel to device, and to promote vessel dilation.
摘要翻译：示例性实施例包括用于创建新的或加强现有侧支血管，和/或将邻近血管桥接在一起的AV瘘和其它吻合装置。为了产生透壁流，示例性实施例可以包括侧壁端口，例如法兰侧壁端口和/或流动框架设计，例如部分裸露的柔性支架或者搅拌器。另一个示例性实施例可以包括顺应容器支撑件，以帮助从装置到容器和/或容器到装置的过渡，并且促进血管扩张。

7. 发明授权

US09381018B2 Device for rapid repair of body conduits 有权
公开(公告)号：US09381018B2
公开(公告)日：2016-07-05
申请号：US13149696
申请日：2011-05-31
申请人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61F2/84 , A61B17/11 , A61F2/07 , A61F2/97 , A61B17/06 , A61F2/06 , A61F2/30 , A61F2/89
CPC分类号： A61F2/07 , A61B17/06166 , A61B17/11 , A61B2017/1107 , A61F2/064 , A61F2/844 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/958 , A61F2/97 , A61F2002/075 , A61F2002/30713 , A61F2220/0075 , A61F2220/0091 , A61F2250/0087
摘要： A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion into a vessel, to the larger diameter at which they fit interferably into a portion of the vessel.

8. 发明授权

US09005269B2 Bioabsorbable self-expanding endolumenal devices 有权
标题翻译：生物可吸收的自扩张腔内装置
公开(公告)号：US09005269B2
公开(公告)日：2015-04-14
申请号：US12181197
申请日：2008-07-28
申请人： Joseph R. Armstrong , Paul C. Begovac , Robert L. Cleek , Edward H. Cully , Charles Flynn , Byron K. Hayes , Ryan V. Peterson , Michael J. Vonesh , Charles F. White
发明人： Joseph R. Armstrong , Paul C. Begovac , Robert L. Cleek , Edward H. Cully , Charles Flynn , Byron K. Hayes , Ryan V. Peterson , Michael J. Vonesh , Charles F. White
IPC分类号： A61F2/82 , A61F2/01 , A61B17/12 , A61F2/91 , A61F2/915 , A61L31/06 , A61L31/14 , A61F2/30
CPC分类号： A61F2/01 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B2017/1205 , A61F2/91 , A61F2/915 , A61F2002/016 , A61F2002/018 , A61F2002/30062 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2210/0004 , A61F2210/0076 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0069 , A61F2230/008 , A61F2250/003 , A61L31/06 , A61L31/148 , C08L67/04
摘要： Bioabsorbable self-expanding medical devices formed of an integral framework with a multiplicity of fenestrations are provided. The framework is continuous, non-filamentous, non-braided, and non-interlaced. The devices includes a non-blended hydrolysable co-polymeric material comprising an amorphous component with a glass transition temperature that is below ambient body temperature and a crystallizable component that possesses a crystalline melting point in excess of ambient body temperature. The devices radially expand from a compressed first diameter to an uncompressed second diameter equal to or greater than 1.5 times the first diameter within two minutes in an aqueous medium at 37° C. following release of a compressive force placed on the devices. Additionally, the medical device does not change axial length significantly as the radial dimensions of the devices are changed. Further, the medical devices may be constructed of different bioabsorbable polymers, polymer ratios, and/or different geometries and portions may bioabsorb at different rates.
摘要翻译：提供由具有多个开窗的整体框架形成的生物可吸收的自扩张医疗装置。框架是连续的，非丝状的，非编织的和非隔行的。该装置包括非共混的可水解共聚物材料，其包含玻璃化转变温度低于环境体温的非晶组分和具有超过环境体温的结晶熔点的可结晶组分。在放置在装置上的压缩力释放之后，装置在37℃下在含水介质中在两分钟内从压缩的第一直径径向膨胀至等于或大于第一直径的1.5倍的未压缩的第二直径。此外，随着装置的径向尺寸改变，医疗装置不会显着改变轴向长度。此外，医疗装置可以由不同的生物可吸收聚合物，聚合物比率和/或不同的几何形状构成，并且部分可以以不同的速率生物吸收。

9. 发明申请

US20120303112A1 STENT 有权
公开(公告)号：US20120303112A1
公开(公告)日：2012-11-29
申请号：US13298060
申请日：2011-11-16
申请人： Joseph R. Armstrong , Edward H. Cully , Michael W. Franklin , Mark Y. Hansen , Brandon A. Lurie , Craig r. McMurray , William D. Montgomery , Wendy J. Terry , Eric M. Tittelbaugh
发明人： Joseph R. Armstrong , Edward H. Cully , Michael W. Franklin , Mark Y. Hansen , Brandon A. Lurie , Craig r. McMurray , William D. Montgomery , Wendy J. Terry , Eric M. Tittelbaugh
IPC分类号： A61F2/82
CPC分类号： A61F2/88 , A61F2/07 , A61F2/915 , A61F2/966 , A61F2002/075 , A61F2002/91558 , A61F2002/91575 , A61F2002/9583 , A61F2220/005 , A61F2220/0075 , A61F2230/0054
摘要： The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by “open” cells and at least two end portions, defined by “closed” cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.
摘要翻译：本发明涉及医疗装置及其使用方法。该装置是可以通过（或在）血管内导管或经由其它手术或其它技术经皮递送的支架，然后扩张。支架被构造成具有由开放细胞限定的中心部分和由闭孔限定的至少两个端部，间隔开并且直接连接到支架的中心部分的远端和近端。支架也可任选地具有带开口的覆盖物或格子。

10. 发明申请

US20120289997A1 Embolic Filter Frame Having Looped Support Strut Elements 有权
标题翻译：具有环形支撑支柱元件的栓塞过滤器框架
公开(公告)号：US20120289997A1
公开(公告)日：2012-11-15
申请号：US13555543
申请日：2012-07-23
申请人： Edward H. Cully , Michael J. Vonesh
发明人： Edward H. Cully , Michael J. Vonesh
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , B23P11/00 , Y10T29/49826
摘要： An embolic frame having looped support struts. The frame configuration provides enhanced longitudinal compliance, improved sealing against a vessel wall, low profile delivery, and a short deployed length. The looped support struts have a high degree of “radial” stiffness with a low degree of “longitudinal” stiffness. In the deployed state, the frame exerts a relatively high stress onto a vessel wall to maintain an effective seal, yet remains compliant in the longitudinal direction. The looped support struts elongate when tensioned and assume a compressed and essentially linear form. While constrained in this linear state by a delivery catheter, the support struts exert minimal stress onto the delivery system. The overall delivery profile and stiffness are therefore reduced. When the delivery catheter constraint is removed during deployment, the struts “snap open” and assume a looped configuration which exert a high degree of force onto the vessel wall.
摘要翻译：具有环状支撑支柱的栓塞框架。框架结构提供增强的纵向顺应性，改进的针对血管壁的密封，薄型输送和短部署长度。环形支撑支柱具有高度的径向刚度，并且具有低程度的纵向刚度。在展开状态下，框架在容器壁上施加相当高的应力以保持有效的密封，但在长度方向保持柔顺。环形支撑件在张紧时伸长并呈现压缩且基本线性的形式。虽然通过输送导管在这种线性状态下被约束，但是支撑支柱对输送系统施加最小的压力。因此，总体输送轮廓和刚度降低。当在展开期间移除输送导管约束时，支柱卡扣打开并且呈现向血管壁施加高度力的环形构造。

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