专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012167117A3 CARBON-LEAD BLENDS FOR USE IN HYBRID ENERGY STORAGE DEVICES 审中-公开
标题翻译：用于混合能源储存装置的碳黑混合物
公开(公告)号：WO2012167117A3
公开(公告)日：2013-11-28
申请号：PCT/US2012040508
申请日：2012-06-01
申请人： ENERG2 TECHNOLOGIES INC , THOMPKINS LEAH A , FEAVER AARON M , COSTANTINO HENRY R , CHANG ALAN TZU-YANG , GERAMITA KATHARINE , SAKSHAUG AVERY , MAROON MATTHEW J
发明人： THOMPKINS LEAH A , FEAVER AARON M , COSTANTINO HENRY R , CHANG ALAN TZU-YANG , GERAMITA KATHARINE , SAKSHAUG AVERY , MAROON MATTHEW J
IPC分类号： H01M4/14
CPC分类号： H01M4/14 , H01G11/50 , H01M4/56 , H01M4/625 , H01M10/06 , Y02E60/13 , Y02T10/7022
摘要： The present application is directed to blends comprising a plurality of carbon particles and a plurality of lead particles. The blends find utility in any number of electrical devices, for example, in lead acid batteries. Methods for making and using the blends are also disclosed.
摘要翻译：本申请涉及包含多个碳颗粒和多个铅颗粒的共混物。混合物可用于任何数量的电气设备，例如铅酸电池。还公开了制备和使用共混物的方法。

2. 发明申请

WO2007014391A2 TIGHT JUNCTION MODULATING PEPTIDE COMPONENTS FOR ENHANCING MUCOSAL DELIVERY 审中-公开
标题翻译：用于增强粘膜递送的轻度连接调节肽组分
公开(公告)号：WO2007014391A2
公开(公告)日：2007-02-01
申请号：PCT/US2006029768
申请日：2006-07-27
申请人： NASTECH PHARM CO , QUAY STEVEN C , QUAY SHU-CHIH CHEN , CUI KUNYUAN , SILENO ANTHONY P , JOHNSON PAUL HICKOK , HOUSTON MICHAEL E , COSTANTINO HENRY R , TEMPLIN MICHAEL V , LAMHARZI NAJIB
发明人： QUAY STEVEN C , QUAY SHU-CHIH CHEN , CUI KUNYUAN , SILENO ANTHONY P , JOHNSON PAUL HICKOK , HOUSTON MICHAEL E , COSTANTINO HENRY R , TEMPLIN MICHAEL V , LAMHARZI NAJIB
IPC分类号： C07K14/435 , A61K38/00
CPC分类号： C07K14/00 , A61K9/0043 , A61K31/55 , A61K38/12 , A61K38/22 , A61K38/23 , A61K45/06 , A61K47/42 , A61K47/60 , A61K2300/00
摘要： Compounds and components including sequences for mucosal epithelial transport of an active agent are given. Tight junction modulating peptide components are described for use in transport and delivery. Permeability can be enhanced with reversibility. Compounds and components for enhanced delivery may be peptide or protein variants, conjugates, or other analog types and structures.
摘要翻译：给出了包括活性剂粘膜上皮转运序列的化合物和组分。描述了紧密连接调节肽组分用于运输和递送。渗透性可以提高可逆性。用于增强递送的化合物和组分可以是肽或蛋白质变体，缀合物或其它类似物和结构。

3. 发明申请

WO0160334A3 METHOD AND APPARATUS FOR UNIFORM SORBATE EQUILIBRATION OF SOLID SAMPLES 审中-公开
标题翻译：固体样品均匀等离子体的方法和装置
公开(公告)号：WO0160334A3
公开(公告)日：2002-03-14
申请号：PCT/US0104586
申请日：2001-02-13
申请人： ALKERMES INC , COSTANTINO HENRY R , BROWN JOSIAH
发明人： COSTANTINO HENRY R , BROWN JOSIAH
IPC分类号： G01N1/28 , G01N15/08 , G01N35/00 , G01N5/04 , G05D22/00
CPC分类号： G01N15/0893 , G01N1/28 , G01N2035/00455
摘要： Solid samples having a uniform sorbate content are produced by directing a gas having a constant sorbate pressure through a plurality of containers, each container enclosing a solid sample. The sorbate content of the solid samples equilibrates with the sorbatepressure in the gas, thereby causing the solid samples to have a uniform sorbate content. An apparatus that can be employed to generate solid samples having a uniform sorbate content includes a relative humidity generator, and a manifold which connects the relative humidity generator to a plurality of solid sample containers.
摘要翻译：具有均匀山梨酸盐含量的固体样品通过将具有恒定的山梨酸盐压力的气体引导通过多个容器来产生，每个容器包围固体样品。固体样品的山梨酸盐含量与气体中的山梨酸盐压力平衡，从而使固体样品具有均匀的山梨酸盐含量。可用于产生具有均匀山梨酸含量的固体样品的装置包括相对湿度发生器和将相对湿度发生器连接到多个固体样品容器的歧管。

4. 发明申请

WO2011002536A3 MANUFACTURING METHODS FOR THE PRODUCTION OF CARBON MATERIALS 审中-公开
标题翻译：生产碳材料的制造方法
公开(公告)号：WO2011002536A3
公开(公告)日：2013-09-06
申请号：PCT/US2010030396
申请日：2010-04-08
申请人： ENERG2 INC , COSTANTINO HENRY R , FEAVER AARON , SCOTT WILLIAM D
发明人： COSTANTINO HENRY R , FEAVER AARON , SCOTT WILLIAM D
IPC分类号： C08J3/00 , C01B3/00 , C01B32/336 , H01G9/00 , H01M4/00 , H01M8/00
CPC分类号： C08G8/28 , B82Y30/00 , C01B3/0021 , C01B32/336 , C08G8/22 , C08J3/12 , C08K5/04 , H01G11/34 , H01M4/96 , H01M8/0234 , Y02E60/13 , Y02E60/325 , Y02P70/56 , Y10T428/2982
摘要： The present application is generally directed to activated carbon materials and methods for making the same. The disclosed methods comprise rapidly freezing synthetically prepared carbon hydrogel particles. The methods further comprise drying, pyrolyzing, and activating the carbon hydrogel particles to obtain an activated carbon material of high porosity. The disclosed methods represent viable manufacturing processes for the preparation of activated carbon materials.
摘要翻译：本申请一般涉及活性炭材料及其制造方法。所公开的方法包括快速冷冻合成制备的碳水凝胶颗粒。所述方法还包括干燥，热解和活化碳水凝胶颗粒以获得高孔隙率的活性炭材料。所公开的方法代表用于制备活性炭材料的可行制造方法。

5. 发明申请

WO2007044069A3 PTH FORMULATIONS AND METHODS OF USE 审中-公开
标题翻译： PTH配方及使用方法
公开(公告)号：WO2007044069A3
公开(公告)日：2009-08-27
申请号：PCT/US2006013377
申请日：2006-04-10
申请人： NASTECH PHARM CO , COSTANTINO HENRY R , QUAY STEVEN C , TEMPLIN MICHAEL V , LI CHING-YUAN , SILENO ANTHONY
发明人： COSTANTINO HENRY R , QUAY STEVEN C , TEMPLIN MICHAEL V , LI CHING-YUAN , SILENO ANTHONY
IPC分类号： A61K38/29 , A61K47/18 , A61K47/24 , A61K47/26 , A61K47/40 , A61P19/10
CPC分类号： A61K9/0043 , A61K38/29 , A61K47/26 , A61K47/40
摘要： What is described is an aqueous pharmaceutical formulation of PTH, comprising PTH(I -34) and a nonionic surface active agent, a dosage form comprising the formulation, a system of delivering PTH to a human, comprising exposing a layer of mucosal cells to the formulation, and a method of using such formulation for treating osteoporosis in a mammal, preferably wherein a time to maximum plasma concentration, Tmax, of PTH(I -34) following administration is less than 30 minutes. Also described is a method for treating osteoporosis in a mammal comprising administering intranasally a PTH formulation comprises a therapeutically effective amount of PTH(I -34) and one or more excipients selected from the group consisting of a solubilizing agent, a chelating agent, and one or more polyols. Comprising PTH(l-34) and a nonionic surface active agent. Also described is a use of PTH(l-34) in the manufacture of a medicament for treating osteoporosis in a mammal, wherein the medicament comprises a therapeutically effective amount of PTH(I -34) and one or more excipients selected from the group consisting of a nonionic surface active agent, a solubilizing agent, a chelating agent, and one or more polyols.
摘要翻译：描述的是含有PTH（I-34）和非离子表面活性剂的PTH水性药物制剂，包含该制剂的剂型，将PTH递送给人的系统，包括将粘膜细胞层暴露于制剂和使用这种制剂治疗哺乳动物骨质疏松症的方法，优选其中施用后PTH（I-34）的时间至最大血浆浓度T max小于30分钟。还描述了一种治疗哺乳动物骨质疏松症的方法，其包括鼻内施用PTH制剂，其包含治疗有效量的PTH（I-34）和一种或多种赋形剂，其选自增溶剂，螯合剂和一种或更多的多元醇。包括PTH（1-34）和非离子表面活性剂。还描述了PTH（1-34）在制备用于治疗哺乳动物的骨质疏松症的药物中的用途，其中所述药物包含治疗有效量的PTH（I-34）和一种或多种选自以下的赋形剂：的非离子表面活性剂，增溶剂，螯合剂和一种或多种多元醇。

6. 发明申请

WO2007067964B1 MUCOSAL DELIVERY OF STABILIZED FORMULATIONS OF EXENDIN 审中-公开
公开(公告)号：WO2007067964B1
公开(公告)日：2007-10-04
申请号：PCT/US2006061760
申请日：2006-12-07
申请人： NASTECH PHARM CO , QUAY STEVEN C , COSTANTINO HENRY R , LEONARD ALEXIS KAYS
发明人： QUAY STEVEN C , COSTANTINO HENRY R , LEONARD ALEXIS KAYS
IPC分类号： A61K38/26 , A61K9/12 , A61P3/00
CPC分类号： A61K9/0043 , A61K9/006 , A61K38/2278 , A61K47/40
摘要： What is described is a pharmaceutical formulation for intranasal administration of exendin to a mammal, wherein the formulation comprises a therapeutically effective amount of an exendin, a viscosity enhancer, methyl-ß-cyclodextrin, a surfactant, tartrate buffer to control pH and a chelating agent for cations, and wherein such exendin dosage form exhibits at least 95% exenatide recovery after storage for at least 365 days at 5°C.

7. 发明申请

WO2007014391B1 TIGHT JUNCTION MODULATING PEPTIDE COMPONENTS FOR ENHANCING MUCOSAL DELIVERY OF THERAPEUTIC AGENTS 审中-公开
标题翻译：用于增强治疗药物的粘膜递送的轻度结节调节肽组分
公开(公告)号：WO2007014391B1
公开(公告)日：2007-08-16
申请号：PCT/US2006029768
申请日：2006-07-27
申请人： NASTECH PHARM CO , QUAY STEVEN C , QUAY SHU-CHIH CHEN , CUI KUNYUAN , SILENO ANTHONY P , JOHNSON PAUL HICKOK , HOUSTON MICHAEL E , COSTANTINO HENRY R , TEMPLIN MICHAEL V , LAMHARZI NAJIB
发明人： QUAY STEVEN C , QUAY SHU-CHIH CHEN , CUI KUNYUAN , SILENO ANTHONY P , JOHNSON PAUL HICKOK , HOUSTON MICHAEL E , COSTANTINO HENRY R , TEMPLIN MICHAEL V , LAMHARZI NAJIB
IPC分类号： C07K14/435 , A61K38/00
CPC分类号： C07K14/00 , A61K9/0043 , A61K31/55 , A61K38/12 , A61K38/22 , A61K38/23 , A61K45/06 , A61K47/42 , A61K47/60 , A61K2300/00
摘要： Compounds and components including sequences for mucosal epithelial transport of an active agent are given. Tight junction modulating peptide components are described for use in transport and delivery. Permeability can be enhanced with reversibility. Compounds and components for enhanced delivery may be peptide or protein variants, conjugates, or other analog types and structures.
摘要翻译：给出了包括活性剂粘膜上皮转运序列的化合物和组分。描述了紧密连接调节肽组分用于运输和递送。渗透性可以提高可逆性。用于增强递送的化合物和组分可以是肽或蛋白质变体，缀合物或其它类似物和结构。

8. 发明申请

WO2005115441A3 COMPOSITIONS AND METHODS FOR ENHANCED MUCOSAL DELIVERY OF PARATHYROID HORMONE 审中-公开
标题翻译：组合物和方法，用于增强间皮瘤的输送
公开(公告)号：WO2005115441A3
公开(公告)日：2006-03-16
申请号：PCT/US2005016530
申请日：2005-05-10
申请人： NASTECH PHARM CO , QUAY STEVEN C , COSTANTINO HENRY R , KLEPPE MARY S , LI CHING-YUAN
发明人： QUAY STEVEN C , COSTANTINO HENRY R , KLEPPE MARY S , LI CHING-YUAN
IPC分类号： A61K9/00 , A61K9/127 , A61K31/724 , A61K38/29 , A61K47/00 , A61K47/18 , A61K47/30 , A61K47/48 , A61P5/18 , A61P19/10
CPC分类号： A61K31/724 , A61K9/0043 , A61K38/29 , A61K47/183
摘要： Pharmaceutical compositions and methods are described comprising at least a parathyroid hormone peptide (PTH) preferably PTH 1-34 and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of PTH, for treating or preventing osteoporosis or osteopenia in a mammalian subject, preferably a human.
摘要翻译：描述了药物组合物和方法，其至少包含甲状旁腺激素肽（PTH），优选PTH <1-34 和一种或多种用于增强鼻粘膜递送PTH的粘膜递送增强剂，用于治疗或预防骨质疏松症或哺乳动物受试者，优选人类的骨质减少。

9. 发明申请

WO2007067964A2 MUCOSAL DELIVERY OF STABILIZED FORMULATIONS OF EXENDIN 审中-公开
标题翻译：胶囊输送稳定剂的配方
公开(公告)号：WO2007067964A2
公开(公告)日：2007-06-14
申请号：PCT/US2006061760
申请日：2006-12-07
申请人： NASTECH PHARM CO , QUAY STEVEN C , COSTANTINO HENRY R , LEONARD ALEXIS KAYS
发明人： QUAY STEVEN C , COSTANTINO HENRY R , LEONARD ALEXIS KAYS
IPC分类号： A61K38/26 , A61K9/12 , A61P3/00
CPC分类号： A61K9/0043 , A61K9/006 , A61K38/2278 , A61K47/40
摘要： What is described is a pharmaceutical formulation for intranasal administration of exendin to a mammal, wherein the formulation comprises a therapeutically effective amount of an exendin, a viscosity enhancer, methyl-ß-cyclodextrin, a surfactant, tartrate buffer to control pH and a chelating agent for cations, and wherein such exendin dosage form exhibits at least 95% exenatide recovery after storage for at least 365 days at 5°C.
摘要翻译：描述的是用于向哺乳动物鼻内施用毒蜥外泌肽的药物制剂，其中所述制剂包含治疗有效量的毒蜥外泌肽，粘度增强剂，甲基-β-环糊精，表面活性剂，控制pH的酒石酸盐缓冲剂和螯合剂对于阳离子，并且其中所述毒蜥外泌肽剂型在5℃下储存至少365天后显示出至少95％的艾塞那肽恢复。

10. 发明申请

WO2007044375A2 PTH FORMULATIONS AND METHODS OF USE 审中-公开
标题翻译： PTH配方及使用方法
公开(公告)号：WO2007044375A2
公开(公告)日：2007-04-19
申请号：PCT/US2006038735
申请日：2006-10-03
申请人： NASTECH PHARM CO , COSTANTINO HENRY R , QUAY STEVEN C , TEMPLIN MICHAEL V , LI CHING-YUAN , SILENO ANTHONY P , PRINN KRISTIN B
发明人： COSTANTINO HENRY R , QUAY STEVEN C , TEMPLIN MICHAEL V , LI CHING-YUAN , SILENO ANTHONY P , PRINN KRISTIN B
IPC分类号： A61K38/29 , A61K47/18 , A61K47/24 , A61K47/26 , A61K47/40 , A61P19/10
CPC分类号： A61K9/0043 , A61K38/29 , A61K47/183 , A61K47/24 , A61K47/26 , A61K47/40
摘要： What is described is an aqueous pharmaceutical formulation of PTH, comprising a therapeutically effective amount of PTH(l-34) and one or more excipients selected from the group consisting of a solubilizing agent, a chelating agent, one or more polyols, and a nonionic surface active agent, a method of using such formulation for treating osteoporosis in a mammal by intranasal administration, and use of PTH(I -34) in the manufacture of such formulation for treating osteoporosis in a mammal.
摘要翻译：描述的是PTH的水性药物制剂，其包含治疗有效量的PTH（1-34）和一种或多种赋形剂，其选自增溶剂，螯合剂，一种或多种多元醇和非离子表面活性剂表面活性剂，使用这种制剂通过鼻内给药治疗哺乳动物的骨质疏松症的方法，以及在制备用于治疗哺乳动物骨质疏松症的制剂中使用PTH（I-34）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式