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1. 发明申请

WO0177059A3 Carbonylation of lower alkyl alcohols and their derivatives using metals supported on carbonized polysulfonated divinylbenzene-styrene copolymers 审中-公开
标题翻译：使用负载在碳化多磺化二乙烯基苯 - 苯乙烯共聚物上的金属羰基化低级烷基醇及其衍生物
公开(公告)号：WO0177059A3
公开(公告)日：2002-04-25
申请号：PCT/US0107729
申请日：2001-03-12
申请人： EASTMAN CHEM CO
发明人： ZOELLER JOSEPH ROBERT , SINGLETON ANDY HUGH , TUSTIN GERALD CHARLES , CARVER DONALD LEE
IPC分类号： B01J31/06 , B01J31/26 , B01J31/30 , B01J32/00 , C07B61/00 , C07C51/12 , C07C53/08 , C07C67/36 , C07C69/14 , C07C53/00
CPC分类号： C07C51/12 , C07C67/36 , C07C53/08 , C07C69/14
摘要： A method for producing esters, carboxylic acids and mixtures thereof includes contacting, under carbonylation conditions, lower alkyl alcohols, ethers, lower alkyl alcohol derivatives and mixtures thereof and carbon monoxide with a catalyst having a catalytically effective amount a metal selected from iron, cobalt, nickel, ruthenium, rhodium, palladium, osmium, iridium, platinum, tin and mixtures thereof associated with a carbonized polysulfonated divinylbenzene-styrene copolymer matrix. In a preferred aspect of the invention the method is carried out under vapor-phase conditions.

2. 发明申请

WO2006039268A3 PHARMACEUTICAL FORMULATIONS CONTAINING VITAMIN E TPGS MOLECULES THAT SOLUBILIZE LIPOPHILIC DRUGS WITHOUT SIGNIFICANT EFFLUX INHIBITION, AND USE OF SUCH FORMULATIONS 审中-公开
标题翻译：含有维生素E的药物制剂可以解决没有明显的抑制作用的脂多糖的TPGS分子，以及这些制剂的使用
公开(公告)号：WO2006039268A3
公开(公告)日：2006-07-27
申请号：PCT/US2005034587
申请日：2005-09-29
申请人： EASTMAN CHEM CO
发明人： HYATT JOHN ANTHONY , ZIMA GEORGE CHESTER , EDGAR KEVIN JOSEPH , NAVARRO LISA TONNER , LEHR CLAUS-MICHAEL , COLLNOT EVA-MARIA , SINGLETON ANDY HUGH , BALDES CHRISTIANE , SCHAFER ULRICH FRIEDRICH , WEMPE MICHAEL FITZPATRICK
IPC分类号： A61K9/14 , A61K9/16 , A61K9/20 , A61K9/48 , A61K9/50
CPC分类号： A61K9/16 , A61K9/14 , A61K9/20 , A61K9/48 , A61K9/50
摘要： Compounds and compositions are disclosed for increasing the bioavailability of lipophilic drugs, and more specifically, to solubilizing lipophilic drugs using bioenhancers that cause no efflux inhibition or a desired degree of efflux inhibition. Methods of making and using such compositions are also disclosed.
摘要翻译：公开了用于增加亲脂性药物的生物利用度的化合物和组合物，更具体地，使用不引起外排抑制或期望程度的排出抑制的生物降解剂来增溶亲脂性药物。还公开了制备和使用这些组合物的方法。

3. 发明申请

WO2006115713A2 EUTECTIC BLENDS CONTAINING A WATER SOLUBLE VITAMIN DERIVATIVE 审中-公开
标题翻译：含有水溶性维生素衍生物的保护性混合物
公开(公告)号：WO2006115713A2
公开(公告)日：2006-11-02
申请号：PCT/US2006012479
申请日：2006-04-04
申请人： EASTMAN CHEM CO
发明人： SINGLETON ANDY HUGH
IPC分类号： A61K31/192 , A61K9/08 , A61K31/355
CPC分类号： A61K9/4858 , A61K31/192 , A61K31/355 , A61K31/60
摘要： An eutectic composition having from (10) to (90) weight % of a first component comprising a pharmaceutically acceptable substituted C 6 -C 10 aryl compound wherein the aryl moiety includes a straight or branched moiety selected from the group consisting of C 1 -C 12 alkyl, C 1 -C 12 alkoxy, C 2 -C 6 alkanoyloxy, hydroxy, carboxy, carboxy substituted C 1 -C 12 alkyl and mixtures and isomers thereof. The composition also includes from (10) to (90) weight % of a second component comprising a water-soluble preparation of a fat-soluble vitamin. Also disclosed is a method for preparing the eutectic composition of the present invention. The method includes the steps of forming a mixture from a predetermined amount of the first component with a predetermined amount of the second component, heating the mixture to melt at least one of the components, and mixing the components to form an eutectic blend. In a preferred embodiment, the method further includes the step of cooling the eutectic blend.
摘要翻译：具有（10）至（90）重量％的包含药学上可接受的取代的C 6 -C 10芳基化合物的第一组分的共晶组合物，其中芳基部分包括 C 1 -C 12烷基，C 1 -C 12烷基，C 1 -C 12烷基，C 1 -C 12烷基，C 1 -C 12 - 烷氧基，C 2 -C 6烷酰氧基，羟基，羧基，羧基取代的C 1 -C 12烷基和混合物和异构体。组合物还包括（10）至（90）重量％的包含脂溶性维生素的水溶性制剂的第二组分。还公开了制备本发明的共晶组合物的方法。该方法包括以下步骤：用预定量的第二组分从预定量的第一组分形成混合物，加热混合物以熔化至少一种组分，并混合组分以形成共晶共混物。在优选的实施方案中，该方法还包括冷却共晶共混物的步骤。

4. 发明申请

WO0177053A3 CARBONYLATION CATALYST SUPPORTED ON A CARBONIZED POLYSULFONATED DIVINYLBENZENE-STYRENE COPOLYMER 审中-公开
标题翻译：碳化聚苯乙烯苯乙烯共聚物上的碳纳米管催化剂
公开(公告)号：WO0177053A3
公开(公告)日：2002-01-24
申请号：PCT/US0107818
申请日：2001-03-12
申请人： EASTMAN CHEM CO
发明人： ZOELLER JOSEPH ROBERT , SINGLETON ANDY HUGH , TRISTIN GERALD CHARLES , CARVER DONALD LEE
IPC分类号： B01J23/14 , B01J23/42 , B01J23/46 , B01J31/10 , B01J31/26 , B01J31/28 , B01J31/30 , B01J32/00 , C07B61/00 , C07C27/00 , C07C51/12 , C07C53/08 , C07C67/36 , C07C69/14 , B01J37/08 , B01J21/18
CPC分类号： C07C51/12 , B01J23/14 , B01J23/42 , B01J23/464 , B01J23/468 , B01J31/10 , B01J31/26 , B01J31/30 , C07C67/36 , C07C53/08 , C07C69/14
摘要： A catalyst in carbonylation processes for producing esters, carboxylic acids, and carboxylic acid anhydrides from lower alkyl alcohols, ethers, esters, alcohol producing derivatives. The catalyst includes a catalytically active metal selected from Group VIII metals, tin mixtures thereof associated with a carbonized polysulfonated divinylbenzene-styrene copolymer.
摘要翻译：用于从低级烷基醇，醚，酯，产醇衍生物生产酯，羧酸和羧酸酐的羰基化方法中的催化剂。催化剂包括选自VIII族金属的催化活性金属，其与碳化的多磺化二乙烯基苯 - 苯乙烯共聚物的锡混合物。

5. 发明专利

AT307104T 未知
公开(公告)号：AT307104T
公开(公告)日：2005-11-15
申请号：AT02742143
申请日：2002-06-17
申请人： EASTMAN CHEM CO
发明人： ZOELLER JOSEPH ROBERT , SINGLETON ANDY HUGH , TUSTIN GERALD CHARLES , CARVER DONALD LEE
IPC分类号： C07B61/00 , C07C51/12 , C07C53/08 , C07C67/36 , C07C67/37 , C07C69/14

6. 发明专利

GR3036823T3 CLEAR AEROSOL HAIR SPRAY FORMULATIONS CONTAINING A SULFOPOLYESTER IN A HYDROALCOHOLIC LIQUID VEHICLE 未知
公开(公告)号：GR3036823T3
公开(公告)日：2002-01-31
申请号：GR20010401684
申请日：2001-10-08
申请人： EASTMAN CHEM CO
发明人： GEORGE SCOTT ELLERY , UNDERWOOD VICKI LYNN , GARBER DENNIS MICHAEL , SINGLETON ANDY HUGH
IPC分类号： A61K8/00 , A61K8/02 , A61K8/04 , A61K8/31 , A61K8/34 , A61K8/36 , A61K8/362 , A61K8/368 , A61K8/81 , A61K8/85 , A61Q5/00 , A61Q5/06 , A61K7/06
摘要： This invention relates to an aerosol hair spray formulation containing 0.5 to 15 weight percent of a water-dispersible or water-dissipatible, linear sulfopolyester having a Tg of 40 DEG C. to 50 DEG C. and an inherent viscosity of 0.24 to 0.60 dl/g which contains repeat units from 20 to 26 mole percent dimethyl-5-sodiosulfoisophthalate and 74 to 80 mole percent isophthalic acid, based on 100 mole percent dicarboxylic acid; 10 to 30 mole percent 1,4-cyclohexanedimethanol and 70 to 90 mole percent diethylene glycol, based on 100 mole percent diol; and up to 60 weight percent of an alcohol. The aerosol hair spray formulations are clear, have improved dry time and curl retention, and exhibit less than 20 NTU's, which is a measure of turbidity, even at high concentrations of alcohol.

7. 发明专利

AT202920T 未知
公开(公告)号：AT202920T
公开(公告)日：2001-07-15
申请号：AT95920513
申请日：1995-05-17
申请人： EASTMAN CHEM CO
发明人： GEORGE SCOTT ELLERY , UNDERWOOD VICKI LYNN , GARBER DENNIS MICHAEL , SINGLETON ANDY HUGH
IPC分类号： A61K8/00 , A61K8/02 , A61K8/04 , A61K8/31 , A61K8/34 , A61K8/36 , A61K8/362 , A61K8/368 , A61K8/81 , A61K8/85 , A61Q5/00 , A61Q5/06 , A61K7/06
摘要： This invention relates to an aerosol hair spray formulation containing 0.5 to 15 weight percent of a water-dispersible or water-dissipatible, linear sulfopolyester having a Tg of 40 DEG C. to 50 DEG C. and an inherent viscosity of 0.24 to 0.60 dl/g which contains repeat units from 20 to 26 mole percent dimethyl-5-sodiosulfoisophthalate and 74 to 80 mole percent isophthalic acid, based on 100 mole percent dicarboxylic acid; 10 to 30 mole percent 1,4-cyclohexanedimethanol and 70 to 90 mole percent diethylene glycol, based on 100 mole percent diol; and up to 60 weight percent of an alcohol. The aerosol hair spray formulations are clear, have improved dry time and curl retention, and exhibit less than 20 NTU's, which is a measure of turbidity, even at high concentrations of alcohol.

8. 发明专利

ES2086952T3 未知
公开(公告)号：ES2086952T3
公开(公告)日：1996-07-01
申请号：ES93916978
申请日：1993-07-06
申请人： EASTMAN CHEM CO
发明人： SINGLETON ANDY HUGH , PORTER SANDRA NICHOLSON
IPC分类号： A61K8/37 , A61K47/14 , A61Q5/08 , A61Q5/10 , C11D3/20 , C11D3/39 , C11D17/00 , A61K7/135 , A61K7/06 , A61K7/48 , A61K7/50

9. 发明专利

DK0649301T3 未知
公开(公告)号：DK0649301T3
公开(公告)日：1996-05-13
申请号：DK93916978
申请日：1993-07-06
申请人： EASTMAN CHEM CO
发明人： SINGLETON ANDY HUGH , PORTER SANDRA NICHOLSON
IPC分类号： A61K8/37 , A61K47/14 , A61Q5/08 , A61Q5/10 , C11D3/20 , C11D3/39 , C11D17/00 , A61K7/135 , A61K7/06 , A61K7/48 , A61K7/50

10. 发明专利

DE60225800T2 未知
公开(公告)号：DE60225800T2
公开(公告)日：2009-04-16
申请号：DE60225800
申请日：2002-06-17
申请人： EASTMAN CHEM CO
发明人： ZOELLER JOSEPH ROBERT , SINGLETON ANDY HUGH , TUSTIN GERALD CHARLES , CARVER DONALD LEE
IPC分类号： C07C67/36 , C07B61/00 , C07C51/12 , C07C67/37 , C07C69/14
摘要： A vapor-phase carbonylation method for producing esters and carboxylic acids from reactants comprising lower alkyl alcohols, lower alkyl alcohol generating compounds, and mixtures thereof. The method includes contacting the reactants and carbon monoxide in a carbonylation zone of a carbonylation reactor under vapor-phase conditions with a catalyst having a catalytically effective amount of iridium and tin associated with a solid carrier material.

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