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    • 3. 发明申请
    • METHOD TO PRODUCE FUNCTIONALIZED, LOW VISCOSITY ETHYLENE-BASED POLYMERS
    • 生产功能性低粘度乙烯基聚合物的方法
    • WO2015102886A2
    • 2015-07-09
    • PCT/US2014/070647
    • 2014-12-16
    • DOW GLOBAL TECHNOLOGIES LLC
    • READ, Michael, D.BAWISKAR, Santosh, S.
    • C08F8/00C08F255/02
    • C08F255/02C08K5/092C08K5/14C08F222/06C08L23/08
    • The invention provides a process to form a "functionalized ethylene-based polymer" from an ethylene-based polymer and at least one polar compound, said process comprising thermally treating a composition comprising the ethylene-based polymer, the at least one polar compound, and at least one peroxide, in at least one extruder comprising at least one barrel, to form a polymer melt; and wherein the at least one peroxide has a half life, at the maximum barrel temperature of the at least one extruder, of less than of the minimum residence time of the polymer melt in the at least one extruder. The invention further provides a composition comprising at least the following: a) an ethylene-based polymer comprising a melt viscosity, at 350°F (177°C), less than 50.000 cP, and b) at least one peroxide comprising a half-life from 0.10 to 2.00 minutes, at a temperature from 160°C to 190°C.
    • 本发明提供从乙烯类聚合物和至少一种极性化合物形成“官能化乙烯类聚合物”的方法,所述方法包括热处理包含乙烯基聚合物,至少一种极性化合物和 至少一种过氧化物,至少包含至少一个桶的挤出机,以形成聚合物熔体; 并且其中所述至少一种过氧化物在所述至少一个挤出机的最大桶温下具有小于聚合物熔体在至少一个挤出机中的最小停留时间的半衰期。 本发明还提供一种至少包含以下物质的组合物:a)在350°F(177℃)下小于50.000cP的熔体粘度的乙烯类聚合物,和b)至少一种包含半 - 寿命为0.10至2.00分钟,温度为160℃至190℃。
    • 8. 发明申请
    • INJECTION-MOLDED DOSAGE FORM
    • 注射剂型剂型
    • WO2013055668A1
    • 2013-04-18
    • PCT/US2012/059323
    • 2012-10-09
    • DOW GLOBAL TECHNOLOGIES LLC
    • READ, Michael, D.COPPENS, Karen, A.HALL, Mark, J.ZHAO, Jin
    • C08L1/28A61K9/48C08L5/00
    • A61K9/4816A61K9/4833A61K9/4883C08K5/0016C08K5/05C08L1/28C08L1/286C08L5/00
    • An injection-molded shell of a dosage form of good quality is producible by a) providing a composition comprising i) from 25 to 90 weight percent of ethylcellulose, ii) from 7.5 to 60 weight percent of a polysaccharide or polysaccharide derivative being different from ethylcellulose, and iii) from 2.5 to 50 weight percent of at least one component being different from polysaccharides and polysaccharide derivatives, based on the total weight of the composition, with the proviso that the composition comprises zero or not more than 10 weight percent of gelatin and zero or not more than 10 weight percent of a polymer comprising homo- or copolymerized acrylic acid, homo- or copolymerized methacrylic acid, a homo- or copolymerized acrylate or a homo- or copolymerized methacrylate, and b) subjecting the composition to shearing and heat to plasticize the composition and injection- molding the plasticized composition into a three-dimensional shell of a dosage form.
    • 具有良好质量的剂型的注射成型的外壳可以通过以下方式生产:a)提供组合物,其包含i)25至90重量%的乙基纤维素,ii)7.5至60重量%的不同于乙基纤维素的多糖或多糖衍生物 ,和iii)基于组合物的总重量,2.5至50重量%的至少一种与多糖和多糖衍生物不同的组分,条件是组合物包含零或不大于10重量%的明胶和 0或不超过10重量%的包含均聚或共聚的丙烯酸,均聚或共聚的甲基丙烯酸,均聚或共聚的丙烯酸酯或均聚或共聚的甲基丙烯酸酯的聚合物的聚合物,和b)使组合物经受剪切和加热 塑化组合物并将增塑组合物注塑成剂型的三维壳。