专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2014039684A1 FAD3 PERFORMANCE LOCI AND CORRESPONDING TARGET SITE SPECIFIC BINDING PROTEINS CAPABLE OF INDUCING TARGETED BREAKS 审中-公开
标题翻译： FAD3性能位置和相应目标位点特异性结合蛋白质可诱导目标突变
公开(公告)号：WO2014039684A1
公开(公告)日：2014-03-13
申请号：PCT/US2013/058267
申请日：2013-09-05
申请人： DOW AGROSCIENCES LLC , SANGAMO BIOSCIENCES, INC.
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R. , GUPTA, Manju , AINLEY, William Michael , HENRY, Matthew J. , MILLER, Jeffrey C. , GUSCHIN, Dmitry Y.
IPC分类号： C12N5/10
CPC分类号： C12N15/79 , C12N9/22 , C12N15/63 , C12N15/8241 , C12N15/8247
摘要： A method of gene editing or gene stacking within a FAD3 loci by cleaving, in a site directed manner, a location in a FAD3 gene in a cell, to generate a break in the FAD3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.
摘要翻译：通过以位点方式切割细胞中FAD3基因的位置，在FAD3基因座中进行基因编辑或基因堆积的方法，以在FAD3基因中产生断裂，然后连接到断裂中，与核酸分子缔合公开了一种或多种感兴趣的特征。

2. 发明申请

WO2014165612A2 METHODS AND COMPOSITIONS FOR INTEGRATION OF AN EXOGENOUS SEQUENCE WITHIN THE GENOME OF PLANTS 审中-公开
标题翻译：在植物基因组中整合外源序列的方法和组合
公开(公告)号：WO2014165612A2
公开(公告)日：2014-10-09
申请号：PCT/US2014/032706
申请日：2014-04-02
申请人： DOW AGROSCIENCES LLC , SANGAMO BIOSCIENCES, INC.
发明人： AINLEY, W. Michael , GUSCHIN, Dmitry Y. , HAYDEN, Matthew , ISENEGGER, Daniel , MASON, John , MILLER, Jeffrey C. , PETOLINO, Joseph F. , RAN, Yidong , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R.
IPC分类号： C12N15/82
CPC分类号： C12N15/8213 , C12N15/8274 , C12N15/8278 , C12N15/90 , C12N2800/80
摘要： Disclosed herein are methods and compositions for parallel or sequential transgene stacking in plants to produce plants with selected phenotypes.
摘要翻译：本文公开了用于在植物中平行或顺序转基因堆叠以产生具有选定表型的植物的方法和组合物。

3. 发明申请

WO2014039692A2 FAD2 PERFORMANCE LOCI AND CORRESPONDING TARGET SITE SPECIFIC BINDING PROTEINS CAPABLE OF INDUCING TARGETED BREAKS 审中-公开
标题翻译： FAD2性能位置和相应目标位点特异性结合蛋白质可诱导目标突变
公开(公告)号：WO2014039692A2
公开(公告)日：2014-03-13
申请号：PCT/US2013/058283
申请日：2013-09-05
申请人： DOW AGROSCIENCES LLC , SANGAMO BIOSCIENCES, INC.
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven, R. , GUPTA, Manju , AINLEY, William, Michael , HENRY, Matthew, J. , MILLER, Jeffrey, C. , GUSCHIN, Dmitry, Y.
IPC分类号： C12N15/66
CPC分类号： C12N15/8216 , C07K14/4702 , C07K2319/81 , C12N9/22 , C12N15/102 , C12N15/66 , C12N15/822 , C12N15/8247 , C12N15/902 , C12Y301/00
摘要： A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.
摘要翻译： FAD2基因座中的基因编辑或基因堆积的方法，以位点方式，以细胞中FAD2基因的位置切割，在FAD2基因中产生断裂，然后连接到断裂中，与核酸分子缔合公开了一种或多种感兴趣的特征。

4. 发明公开

EP2981166A2 METHODS AND COMPOSITIONS FOR INTEGRATION OF AN EXOGENOUS SEQUENCE WITHIN THE GENOME OF PLANTS 有权转让
标题翻译：方法和组合物外源序列在植物的基因组整合
公开(公告)号：EP2981166A2
公开(公告)日：2016-02-10
申请号：EP14778180.1
申请日：2014-04-02
申请人： Dow AgroSciences LLC , Sangamo BioSciences, Inc.
发明人： AINLEY, W. Michael , GUSCHIN, Dmitry Y. , HAYDEN, Matthew , ISENEGGER, Daniel , MASON, John , MILLER, Jeffrey C. , PETOLINO, Joseph F. , RAN, Yidong , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R.
IPC分类号： A01H1/00
摘要： Disclosed herein are methods and compositions for parallel or sequential transgene stacking in plants to produce plants with selected phenotypes.

5. 发明公开

EP2893023A2 FAD2 PERFORMANCE LOCI AND CORRESPONDING TARGET SITE SPECIFIC BINDING PROTEINS CAPABLE OF INDUCING TARGETED BREAKS 有权转让
标题翻译： FAD2表现特定基因和相应目标位点特异性结合蛋白能够诱导靶向突破
公开(公告)号：EP2893023A2
公开(公告)日：2015-07-15
申请号：EP13834887.5
申请日：2013-09-05
申请人： Dow AgroSciences LLC , Sangamo BioSciences, Inc.
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven, R. , GUPTA, Manju , AINLEY, William, Michael , HENRY, Matthew, J. , MILLER, Jeffrey, C. , GUSCHIN, Dmitry, Y.
IPC分类号： C12N15/66
CPC分类号： C12N15/8216 , C07K14/4702 , C07K2319/81 , C12N9/22 , C12N15/102 , C12N15/66 , C12N15/822 , C12N15/8247 , C12N15/902 , C12Y301/00
摘要： Methods and compositions for gene disruption, gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a soybean cell, to generate a break in the FAD2 gene and then optionally integrating into the break a nucleic acid molecule of interest is disclosed.
摘要翻译：通过以定点方式切割FAD2基因在细胞中的位置来在FAD2基因座中进行基因编辑或基因堆叠以在FAD2基因中产生断裂，然后将与之相关的核酸分子披露了一个或多个感兴趣的特征。

6. 发明公开

EP2893006A1 FAD3 PERFORMANCE LOCI AND CORRESPONDING TARGET SITE SPECIFIC BINDING PROTEINS CAPABLE OF INDUCING TARGETED BREAKS 有权转让
标题翻译： FAD3-PERFORMANCE位点与任务目标设定具体的结合蛋白诱导靶BREAKS
公开(公告)号：EP2893006A1
公开(公告)日：2015-07-15
申请号：EP13834682.0
申请日：2013-09-05
申请人： Dow AgroSciences LLC , Sangamo BioSciences, Inc.
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R. , GUPTA, Manju , AINLEY, William Michael , HENRY, Matthew J. , MILLER, Jeffrey C. , GUSCHIN, Dmitry Y.
IPC分类号： C12N5/10
CPC分类号： C12N15/79 , C12N9/22 , C12N15/63 , C12N15/8241 , C12N15/8247
摘要： A method of gene editing or gene stacking within a FAD3 loci by cleaving, in a site directed manner, a location in a FAD3 gene in a cell, to generate a break in the FAD3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.

7. 发明申请

WO2014039970A1 FLUORESCENCE ACTIVATED CELL SORTING (FACS) ENRICHMENT TO GENERATE PLANTS 审中-公开
标题翻译：荧光激活细胞分选（FACS）生产植物
公开(公告)号：WO2014039970A1
公开(公告)日：2014-03-13
申请号：PCT/US2013/058766
申请日：2013-09-09
申请人： DOW AGROSCIENCES LLC
发明人： SPANGENBERG, German , SAHAB, Sareena , MASON, John
IPC分类号： C12N15/82 , C12Q1/24 , A01H5/00
CPC分类号： C12N15/8241 , C12N15/8212 , C12N15/8213
摘要： An Engineered Transgene Integration Platform (ETIP) is described that can be inserted randomly or at targeted locations in plant genomes to facilitate rapid selection and detection of a GOI that is perfectly targeted (both the 3? and 5? ends) at the ETIP genomic location. One element in the invention is the introduction of specific double stranded breaks within the ETIP. In some embodiments, an ETIP is described using zinc finger nuclease binding sites, but may utilize other targeting technologies such as meganucleases, TALs, CRISPRs, or leucine zippers. Also described are compositions of, and methods for producing, transgenic plants wherein the donor or payload DNA expresses one or more products of an exogenous nucleic acid sequence (e.g. protein or RNA) that has been stably-integrated into an ETIP in a plant cell. In embodiments, the ETIP facilitates testing of gene candidates and plant expression vectors from ideation through Development phases.
摘要翻译：描述了可以随机插入植物基因组中的目标位置的工程化转基因整合平台（ETIP），以便于在ETIP基因组位置上完全靶向（3'和5'末端）的GOI的快速选择和检测。本发明中的一个要素是在ETIP内引入特定的双链断裂。在一些实施方案中，使用锌指核酸酶结合位点描述ETIP，但可以利用其它靶向技术，例如大范围核酸酶，TAL，CRISPR或亮氨酸拉链。还描述了转基因植物的组合物和生产方法，其中供体或有效载体DNA表达已经稳定整合到植物细胞中的ETIP中的外源核酸序列（例如蛋白质或RNA）的一种或多种产物。在实施方案中，ETIP有助于从构想到开发阶段测试基因候选物和植物表达载体。

8. 发明申请

WO2015103430A1 SELECTION BASED ON OPTIMAL HAPLOID VALUE TO CREATE ELITE LINES 审中-公开
标题翻译：基于最佳HAPLOID值的选择创建ELITE线
公开(公告)号：WO2015103430A1
公开(公告)日：2015-07-09
申请号：PCT/US2014/073075
申请日：2014-12-31
申请人： DOW AGROSCIENCES LLC
发明人： DAETWYLER, Hans Dieter , HAYES, Benjamin John , ROBBINS, Kelly , HAYDEN, Matthew James , SPANGENBERG, German
IPC分类号： A01H5/00 , C12Q1/68
CPC分类号： A01H1/04 , A01H1/02 , A01H1/08 , C12Q1/6895 , C12Q2600/13
摘要： This disclosure concerns methods for estimating the breeding value of plants for the purpose of producing doubled haploid, for example, to identify selection candidates having high breeding values.
摘要翻译：本公开涉及用于估计植物繁殖价值以产生双倍体单倍体的方法，例如鉴定具有高育种值的选择候选物。

9. 发明申请

WO2014039872A1 ENGINEERED TRANSGENE INTEGRATION PLATFORM (ETIP) FOR GENE TARGETING AND TRAIT STACKING 审中-公开
标题翻译：用于基因定位和路由堆栈的工程变换集成平台（ETIP）
公开(公告)号：WO2014039872A1
公开(公告)日：2014-03-13
申请号：PCT/US2013/058584
申请日：2013-09-06
申请人： DOW AGROSCIENCES LLC
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R. , GUPTA, Manju , AINLEY, W. Mike , HENRY, Matthew J. , MASON, John , KUMAR, Sandeep , NOVAK, Stephen
IPC分类号： C12N15/82 , A01H5/00 , C12N15/29
CPC分类号： C12N15/8241 , C12N15/8213
摘要： An Engineered Transgene Integration Platform (ETIP) is described that can be inserted randomly or at targeted locations in plant genomes to facilitate rapid selection and detection of a GOI that is perfectly targeted (both the 5' and 3' ends) at the ETIP genomic location. One element in the subject disclosure is the introduction of specific double stranded breaks within the ETIP. In some embodiments, an ETIP is described using zinc finger nuclease binding sites, but may utilize other targeting technologies such as meganucleases, CRISPRs, TALs, or leucine zippers. Also described are compositions of, and methods for producing, transgenic plants wherein the donor or payload DNA expresses one or more products of an exogenous nucleic acid sequence (e.g. protein or RNA) that has been stably-integrated into an ETIP in a plant cell. In embodiments, the ETIP facilitates testing of gene candidates and plant expression vectors from ideation through Development phases.
摘要翻译：描述了可以随机或在植物基因组中的目标位置插入工程化转基因整合平台（ETIP），以便于在ETIP基因组位置上完全靶向（5'和3'末端）的GOI的快速选择和检测。主题披露中的一个要素是在ETIP内引入特定的双链断裂。在一些实施方案中，使用锌指核酸酶结合位点描述ETIP，但可以利用其它靶向技术，例如大范围核酸酶，CRISPR，TAL或亮氨酸拉链。还描述了转基因植物的组合物和生产方法，其中供体或有效载体DNA表达已经稳定整合到植物细胞中的ETIP中的外源核酸序列（例如蛋白质或RNA）的一种或多种产物。在实施方案中，ETIP有助于从构想到开发阶段测试基因候选物和植物表达载体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式