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1. 发明授权

US08915741B2 Sleep quality data collection and evaluation 有权
标题翻译：睡眠质量数据收集和评估
公开(公告)号：US08915741B2
公开(公告)日：2014-12-23
申请号：US13215592
申请日：2011-08-23
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
IPC分类号： G09B23/28 , A61B5/0205 , A61B5/00 , A61B5/0488 , A61B5/11 , A61B5/0476 , A61N1/362 , A61B5/08 , A61B5/0496
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
摘要翻译：睡眠质量评估方法包括基于检测到的生理或非生理性患者状况收集数据。使用可植入装置执行检测患者状况和收集数据中的至少一个。可以使用可植入或患者外部的睡眠质量处理器收集的数据来评估睡眠质量。睡眠质量评估的一种方法包括基于睡眠期间的运动障碍或呼吸障碍的发生来计算一个或多个总结度量。

2. 发明申请

US20090228058A1 IMPLANTABLE MEDICAL DEVICE WITH VOICE RESPONDING AND RECORDING CAPACITY 有权
标题翻译：具有语音响应和记录能力的可植入医疗设备
公开(公告)号：US20090228058A1
公开(公告)日：2009-09-10
申请号：US12468648
申请日：2009-05-19
申请人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
发明人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
IPC分类号： A61N1/08 , A61N1/39
CPC分类号： A61N1/37217 , A61N1/3625 , A61N1/3627 , A61N1/37247
摘要： An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of receiving communications in the form of speech spoken by the patient. An acoustic transducer is incorporated within the device which along with associated filtering circuitry enables the voice communication to be used to affect the operation of the device or recorded for later playback.
摘要翻译：一种可植入医疗装置，例如心脏起搏器或植入式心律转复除颤器，具有以患者所说话语的形式接收通信的能力。声学换能器结合在该装置内，连同相关联的滤波电路使声音通信能够用于影响装置的操作或被记录以供稍后播放。

3. 发明授权

US06453201B1 Implantable medical device with voice responding and recording capacity 有权
公开(公告)号：US06453201B1
公开(公告)日：2002-09-17
申请号：US09473466
申请日：1999-12-28
申请人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
发明人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
IPC分类号： A61N1362
CPC分类号： A61N1/37217 , A61N1/3625 , A61N1/3627 , A61N1/37247
摘要： An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of receiving communications in the form of speech spoken by the patient. An acoustic transducer is incorporated within the device which along with associated filtering circuitry enables the voice communication to be used to affect the operation of the device or recorded for later playback.

4. 发明授权

US07962210B2 Implantable medical device with voice responding and recording capacity 有权
标题翻译：具有语音响应和记录能力的植入式医疗设备
公开(公告)号：US07962210B2
公开(公告)日：2011-06-14
申请号：US12468648
申请日：2009-05-19
申请人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
发明人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
IPC分类号： A61N1/362
CPC分类号： A61N1/37217 , A61N1/3625 , A61N1/3627 , A61N1/37247
摘要： An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of receiving communications in the form of speech spoken by the patient. An acoustic transducer is incorporated within the device which along with associated filtering circuitry enables the voice communication to be used to affect the operation of the device or recorded for later playback.
摘要翻译：一种可植入医疗装置，例如心脏起搏器或植入式心律转复除颤器，具有以患者所说话语的形式接收通信的能力。声学换能器结合在该装置内，连同相关联的滤波电路使声音通信能够用于影响装置的操作或被记录以供稍后播放。

5. 发明授权

US06865424B2 Implantable medical device with voice responding and recording capacity 失效
公开(公告)号：US06865424B2
公开(公告)日：2005-03-08
申请号：US10215237
申请日：2002-08-08
申请人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
发明人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
IPC分类号： A61N1/362 , A61N1/372
CPC分类号： A61N1/37217 , A61N1/3625 , A61N1/3627 , A61N1/37247
摘要： An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of receiving communications in the form of speech spoken by the patient. An acoustic transducer is incorporated within the device which along with associated filtering circuitry enables the voice communication to be used to affect the operation of the device or recorded for later playback.

6. 发明申请

US20110306850A1 Sleep quality data collection and evaluation 有权
标题翻译：睡眠质量数据收集和评估
公开(公告)号：US20110306850A1
公开(公告)日：2011-12-15
申请号：US13215592
申请日：2011-08-23
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
IPC分类号： A61B5/00
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
摘要翻译：睡眠质量评估方法包括基于检测到的生理或非生理性患者状况收集数据。使用可植入装置执行检测患者状况和收集数据中的至少一个。可以使用可植入或患者外部的睡眠质量处理器收集的数据来评估睡眠质量。睡眠质量评估的一种方法包括基于睡眠期间的运动障碍或呼吸障碍的发生来计算一个或多个总结度量。

7. 发明授权

US07551962B2 Implantable medical device with voice responding and recording capacity 失效
公开(公告)号：US07551962B2
公开(公告)日：2009-06-23
申请号：US11071984
申请日：2005-03-04
申请人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
发明人： Douglas R. Daum , Qingsheng Zhu , Bruce H. KenKnight
IPC分类号： A61N1/362
CPC分类号： A61N1/37217 , A61N1/3625 , A61N1/3627 , A61N1/37247
摘要： An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of receiving communications in the form of speech spoken by the patient. An acoustic transducer is incorporated within the device which along with associated filtering circuitry enables the voice communication to be used to affect the operation of the device or recorded for later playback.

8. 发明授权

US08626288B2 Systems, devices and methods for modulating autonomic tone 有权
标题翻译：用于调节自主神经色调的系统，装置和方法
公开(公告)号：US08626288B2
公开(公告)日：2014-01-07
申请号：US12397464
申请日：2009-03-04
申请人： Allan C. Shuros , Shantha Arcot-Krishnamurthy , Bruce H. KenKnight , Douglas R. Daum
发明人： Allan C. Shuros , Shantha Arcot-Krishnamurthy , Bruce H. KenKnight , Douglas R. Daum
IPC分类号： A61N1/368
CPC分类号： A61N1/362 , A61N1/36114 , A61N1/3627
摘要： Various embodiments intermittently deliver a sympathetic stimulus, including deliver a sequence of stress-inducing pacing pulses adapted to increase sympathetic tone during the stress-inducing pacing. The stress-inducing pacing results in a parasympathetic reflex after the sequence of stress-inducing pacing. The embodiment further delivers neural stimulation to elicit a parasympathetic response or a sympathetic response in a coordinated manner with respect to the sequence of stress-inducing pacing pulses. The neural stimulation is timed to elicit the parasympathetic response after the sequence of stress-inducing pacing pulses and concurrent with at least a portion of the parasympathetic reflex to the sequence of stress-inducing pacing to enhance a parasympathetic effect of the parasympathetic reflex, or to elicit the sympathetic response during the sequence of stress-inducing pulses to provide a larger sympathetic stimulus, resulting in an enhanced parasympathetic reflex in response to the large sympathetic stimulus.
摘要翻译：各种实施方案间歇地递送交感刺激，包括递送适于在应力诱导起搏期间增加交感神经张力的应力诱发起搏脉冲序列。应激诱导起搏导致应激诱导起搏顺序后的副交感神经反射。该实施方案进一步递送神经刺激以相对于应力诱导起搏脉冲的序列以协调的方式引发副交感神经反应或交感神经反应。神经刺激被定时以在应力诱发起搏脉冲序列之后引起副交感神经反应，并且与应激诱导起搏序列的至少一部分副交感神经反射并发，以增强副交感神经反射的副交感作用，或在应激诱导脉冲序列期间引起交感神经反应以提供更大的交感神经刺激，导致响应于大的交感神经刺激的增强的副交感神经反射。

9. 发明申请

US20090234406A1 SYSTEMS, DEVICES AND METHODS FOR MODULATING AUTONOMIC TONE 有权
标题翻译：用于调制自动音调的系统，设备和方法
公开(公告)号：US20090234406A1
公开(公告)日：2009-09-17
申请号：US12397464
申请日：2009-03-04
申请人： Allan C. Shuros , Shantha Arcot-Krishnamurthy , Bruce H. KenKnight , Douglas R. Daum
发明人： Allan C. Shuros , Shantha Arcot-Krishnamurthy , Bruce H. KenKnight , Douglas R. Daum
IPC分类号： A61N1/368
CPC分类号： A61N1/362 , A61N1/36114 , A61N1/3627
摘要： Various system embodiments comprise means for intermittently delivering a sympathetic stimulus, including means for delivering a sequence of stress-inducing pacing pulses adapted to increase sympathetic tone during the stress-inducing pacing. The stress-inducing pacing results in a parasympathetic reflex after the sequence of stress-inducing pacing. The embodiment further includes means for delivering neural stimulation to elicit a parasympathetic response or a sympathetic response in a coordinated manner with respect to the sequence of stress-inducing pacing pulses. The neural stimulation is timed to elicit the parasympathetic response after the sequence of stress-inducing pacing pulses and concurrent with at least a portion of the parasympathetic reflex to the sequence of stress-inducing pacing to enhance a parasympathetic effect of the parasympathetic reflex, or to elicit the sympathetic response during the sequence of stress-inducing pulses to provide a larger sympathetic stimulus, resulting in an enhanced parasympathetic reflex in response to the large sympathetic stimulus.
摘要翻译：各种系统实施例包括用于间歇地递送交感刺激的装置，包括用于递送适于在应力诱导起搏期间增加交感神经张力的应力诱发起搏脉冲序列的装置。应激诱导起搏导致应激诱导起搏顺序后的副交感神经反射。该实施方案还包括用于递送神经刺激以相对于应力诱导起搏脉冲的序列以协调的方式引发副交感反应或交感反应的装置。神经刺激被定时以在应力诱发起搏脉冲序列之后引起副交感神经反应，并且与应激诱导起搏序列的至少一部分副交感神经反射并发，以增强副交感神经反射的副交感作用，或在应激诱导脉冲序列期间引起交感神经反应以提供更大的交感神经刺激，导致响应于大的交感神经刺激的增强的副交感神经反射。

10. 发明授权

US07257443B2 Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals 失效
标题翻译：用电针信号检测心律的振荡的方法和装置
公开(公告)号：US07257443B2
公开(公告)日：2007-08-14
申请号：US11184325
申请日：2005-07-19
申请人： Joseph M. Pastore , Steven D. Girouard , Bruce H. KenKnight , Qingsheng Zhu , Jiang Ding
发明人： Joseph M. Pastore , Steven D. Girouard , Bruce H. KenKnight , Qingsheng Zhu , Jiang Ding
IPC分类号： A61N1/368
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684
摘要： A cardiac rhythm management device is configured to detect oscillations in cardiac rhythm by comparing electrogram signals during successive heart beats. Upon detection of electrical alternans, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.
摘要翻译：心律管理装置被配置为通过在连续的心搏期间比较电描记图信号来检测心律的振动。在检测到电气交流电时，该装置可以调整其操作行为以补偿该状况的有害影响。

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