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1. 发明授权

US09833487B2 Composition for preventing and treating arthritic diseases 有权
公开(公告)号：US09833487B2
公开(公告)日：2017-12-05
申请号：US12865995
申请日：2009-02-19
申请人： Dong-Suk Park , Myung Chul Yoo , Do-Young Choi , Hyung In Yang , Yong-Hyeon Baek , Jeong-Eun Huh , Kyoung Soo Kim , Yong-Baik Cho , In Ho Jung , Jong Hyun Hur , Jae Dong Lee
发明人： Dong-Suk Park , Myung Chul Yoo , Do-Young Choi , Hyung In Yang , Yong-Hyeon Baek , Jeong-Eun Huh , Kyoung Soo Kim , Yong-Baik Cho , In Ho Jung , Jong Hyun Hur , Jae Dong Lee
IPC分类号： A61K36/355 , A61K36/8964 , A23L33/105
CPC分类号： A61K36/355 , A23L33/105 , A23V2002/00 , A61K36/8964 , A61K2300/00 , A23V2250/21 , A23V2200/306 , A23V2200/316
摘要： In some embodiments, a composition for the treatment and inhibition or prevention of arthritic diseases includes an extract of mixed herbs, the mixed herbs including an active ingredient with Lonicera japonica THUNB and Anemarrhena asphodeloides BUNGE.

2. 发明申请

US20110003018A1 COMPOSITION FOR PREVENTING AND TREATING ARTHRITIC DISEASES 有权
标题翻译：用于预防和治疗神经疾病的组合物
公开(公告)号：US20110003018A1
公开(公告)日：2011-01-06
申请号：US12865995
申请日：2009-02-19
申请人： Dong-Suk Park , Myung Chul Yoo , Do-Young Choi , Hyung In Yang , Yong-Hyeon Baek , Jeong-Eun Huh , Kyoung Soo Kim , Yong-Baik Cho , In Ho Jung , Jong Hyun Hur , Jae Dong Lee
发明人： Dong-Suk Park , Myung Chul Yoo , Do-Young Choi , Hyung In Yang , Yong-Hyeon Baek , Jeong-Eun Huh , Kyoung Soo Kim , Yong-Baik Cho , In Ho Jung , Jong Hyun Hur , Jae Dong Lee
IPC分类号： A61K36/355 , A61K36/896 , A61P19/02 , A61P29/00
CPC分类号： A61K36/355 , A23L33/105 , A23V2002/00 , A61K36/8964 , A61K2300/00 , A23V2250/21 , A23V2200/306 , A23V2200/316
摘要： In some embodiments, a composition for the treatment and inhibition or prevention of arthritic diseases includes an extract of mixed herbs, the mixed herbs including an active ingredient with Lonicera japonica THUNB and Anemarrhena asphodeloides BUNGE.
摘要翻译：在一些实施方案中，用于治疗和抑制或预防关节炎疾病的组合物包括混合草药的提取物，所述混合草药包括与忍冬（Ronicera japonica）THUNB和Anemarrhena asphodeloides BUNGE的活性成分。

3. 发明申请

US20100010205A1 NAPHTHALENE 2-CARBOXYLATE DERIVATIVE USEFUL FOR SYNTHESIZING GEMCITABINE AND A METHOD FOR PREPARING THE SAME 审中-公开
标题翻译：用于合成格列宾的萘甲酸2-羧酸酯衍生物及其制备方法
公开(公告)号：US20100010205A1
公开(公告)日：2010-01-14
申请号：US12375094
申请日：2007-07-30
申请人： Kyu Wann Kim , Kyoung Soo Kim , Young Won Park , Young Jun Park , Won Kyoung Lee
发明人： Kyu Wann Kim , Kyoung Soo Kim , Young Won Park , Young Jun Park , Won Kyoung Lee
IPC分类号： C07H3/02
CPC分类号： C07H19/073 , Y02P20/55
摘要： Disclosed herein are novel naphthalene-2-carboxylate derivatives of Formula (I), which are useful for the synthesis of gemcitabine, as well as a preparation method. The novel derivatives have naphthalene-2-carboxlate as the hydroxy protecting group of 2-deoxy-2,2-difluoro-pentofuranose-1-ulose. (I) wherein R1 and R2 are each independently hydrogen, methyl, chloro, fluoro, bromo, iodo, methoxy, ethoxy or nitro.
摘要翻译：本文公开了式（I）的新颖的萘-2-羧酸酯衍生物，其可用于吉西他滨的合成以及制备方法。该新型衍生物具有萘-2-甲酸酯作为2-脱氧-2,2-二氟 - 戊呋糖-1-尿苷的羟基保护基。（I）其中R 1和R 2各自独立地为氢，甲基，氯，氟，溴，碘，甲氧基，乙氧基或硝基。

4. 发明授权

US06789423B2 Micro inertia sensor and method of manufacturing the same 失效
公开(公告)号：US06789423B2
公开(公告)日：2004-09-14
申请号：US10330710
申请日：2002-12-27
申请人： Seung Do An , Kyoung Soo Kim , Ji Man Cho
发明人： Seung Do An , Kyoung Soo Kim , Ji Man Cho
IPC分类号： G01C1900
CPC分类号： B81C1/00301 , B81B2201/025 , B81B2207/095 , B81C2201/019 , B81C2203/0118 , B81C2203/038 , G01C19/5783 , G01P1/023 , G01P15/0802 , G01P15/125 , G01P2015/0814 , G01P2015/0828 , Y10T428/24322
摘要： The present invention provides a micro inertia sensor and a method of manufacturing the same, the micro inertia sensor includes a lower glass substrate; a lower silicon including a first border, a first fixed point and a side movement sensing structure; an upper silicon including a second border, a second fixed point being connected to a via hole, in which a metal wiring is formed, on an upper side, and an sensing electrode, which correspond to the first border, the first fixed point and the side movement sensing structure; a bonded layer by a eutectic bonding between the upper silicon and the lower silicon; and a upper glass substrate, being positioned on an upper portion of the upper silicon, for providing the via hole on which an electric conduction wiring is formed, thereby aiming at the miniaturization of the product and the simplification of the process.

5. 发明申请

US20130313109A1 OPEN-CELL TYPE APPARATUS FOR PREPARING SODIUM HYPOCHLORITE 审中-公开
标题翻译：用于制备SODIUM HYPOCHLORITE的开孔类型设备
公开(公告)号：US20130313109A1
公开(公告)日：2013-11-28
申请号：US13985382
申请日：2012-03-02
申请人： Kyoung Soo Kim , Soo Kil Pyo , Seg Young Kang
发明人： Kyoung Soo Kim , Soo Kil Pyo , Seg Young Kang
IPC分类号： C25B15/02 , C25B1/26
CPC分类号： C25B15/02 , C01B11/062 , C02F1/4674 , C02F2201/4612 , C02F2201/46155 , C02F2209/02 , C02F2303/22 , C25B1/26 , C25B9/00
摘要： Provided is an open cell-type apparatus for producing sodium hypochlorite based on electrolysis using soft water and salt. The apparatus includes: a sodium hypochlorite generator including a plurality of electrode plates supported by a support, a flow channel for air flow provided above the support and the electrode plates, and an air intake hole and an air exhaust hole which communicate with the flow channel; a cooling unit for lowering a temperature of the flow channel; and a controller for controlling operation of the cooling unit by detecting a temperature of the sodium hypochlorite generator. The apparatus constantly maintains an optimum temperature of the sodium hypochlorite generator in order to produce sodium hypochlorite of a high concentration with high efficiency.
摘要翻译：本发明提供一种基于使用软水和盐的电解生产次氯酸钠的开孔型设备。该装置包括：次氯酸钠发生器，其包括由支撑件支撑的多个电极板，设置在支撑件上方的用于气流的流动通道和电极板，以及与流路连通的进气孔和排气孔 ; 用于降低流动通道的温度的冷却单元; 以及控制器，用于通过检测次氯酸钠发生器的温度来控制冷却单元的操作。该设备不断保持次氯酸钠发生器的最佳温度，以高效率生产高浓度次氯酸钠。

6. 发明申请

US20120295917A1 IMATINIB DICHLOROACETATE AND ANTI-CANCER AGENT COMPRISING THE SAME 审中-公开
标题翻译： IMATINIB DICHLOROACETATE和抗癌剂包括它们
公开(公告)号：US20120295917A1
公开(公告)日：2012-11-22
申请号：US13519522
申请日：2010-12-28
申请人： Kyoung Soo Kim , Young Jun Park , Hyun-Nam Song , Joon Woo Kim
发明人： Kyoung Soo Kim , Young Jun Park , Hyun-Nam Song , Joon Woo Kim
IPC分类号： A61K31/496 , A61P35/00 , A61P35/02 , C07D401/14
CPC分类号： A61K31/496 , C07D401/04
摘要： The present invention relates to imatinib dichloroacetate and an anti-cancer agent comprising the same. The imatinib dichloroacetate of the present invention can inhibit tyrosine kinase as well as induce cancer cells to kill themselves via apoptosis, thereby inhibit growth of cancer cells and lead to their destruction, and show significantly enhanced anti-cancer effects by synergy between imatinib and dichloroacetic acid.
摘要翻译：本发明涉及伊马替尼二氯乙酸酯和包含其的抗癌剂。本发明的伊马替尼二氯乙酸盐可抑制酪氨酸激酶以及诱导癌细胞通过细胞凋亡自身杀死，从而抑制癌细胞的生长并导致其破坏，并通过伊马替尼和二氯乙酸之间的协同作用显示出显着增强的抗癌作用。

7. 发明授权

US6130336A Process for preparing paclitaxel 失效
标题翻译：制备紫杉醇的方法
公开(公告)号：US6130336A
公开(公告)日：2000-10-10
申请号：US242736
申请日：1999-02-23
申请人： Kyoung Soo Kim , Ki Byung Chai , Young Ho Moon , Kwang Ok Lee , Nam Du Kim , Tae Hee Ha , Jung Ae Shin , Gwan Sun Lee , Wan Joo Kim
发明人： Kyoung Soo Kim , Ki Byung Chai , Young Ho Moon , Kwang Ok Lee , Nam Du Kim , Tae Hee Ha , Jung Ae Shin , Gwan Sun Lee , Wan Joo Kim
IPC分类号： C07D305/14 , C07D263/04 , C07D263/06 , C07D413/12 , C07D263/02 , C07D305/00
CPC分类号： C07D263/04 , C07D305/14 , C07D413/12 , Y02P20/55
摘要： The present invention elates to a process for preparing paclitaxel represented by formula (1) characterized in that: (a) an oxazolidine derivative represented by formula (2) or its salt in which X represents halogen, is coupled with a 7-trihaloacetyl-baccatin III represented by formula (3) in which R.sub.1 represents trihaloacetyl, in a solvent in the presence of a condensing agent to produce an oxazolidine substituent-containing taxane represented by formula (4) in which X and R.sub.1 are each as previously defined; (b) the oxazolidine ring is opened in a solvent in the presence of an acid, and the product thus obtained is reacted with benzoyl chloride in the presence of a base to produce a protected paclitaxel wherein the hydroxy group at 7-position is protected with trihaloacetyl group represented by formula (5) in which R.sub.1 is as previously defined; (c) then the protecting group at 7-position is removed by ammonia or a salt of ammonia with a weak acid in a solvent.
摘要翻译： PCT No.PCT / KR97 / 00157 Sec。 371日期1999年2月23日 102（e）1999年2月23日PCT PCT 1997年8月25日PCT公布。出版物WO98 / 08832 1998年3月5日本发明涉及一种制备式（1）表示的紫杉醇的方法，其特征在于：（a）式（2）表示的恶唑烷衍生物或其中X表示卤素的盐与由式（3）表示的7-三卤乙酰基浆果赤霉素III，其中R 1表示三卤代乙酰基，在溶剂中，在缩合剂存在下制备由式（4）表示的含恶唑烷取代基的紫杉烷，其中X和R 1各自为以前定义; （b）在酸存在下，在溶剂中打开恶唑烷环，将得到的产物与苯甲酰氯在碱的存在下反应，得到保护的紫杉醇，其中7位的羟基被由式（5）表示的三卤代乙酰基，其中R 1如前所定义; （c）然后在溶剂中用氨或氨与弱酸将7位保护基除去。

8. 发明申请

US20150121468A1 PHYSICAL LAYER SECURITY METHOD IN WIRELESS LAN AND WIRELESS COMMUNICATION SYSTEM USING THE SAME 审中-公开
标题翻译：无线局域网中的物理层安全方法及其使用的无线通信系统
公开(公告)号：US20150121468A1
公开(公告)日：2015-04-30
申请号：US14399564
申请日：2012-09-13
申请人： Gun Byum Park , Gwan Hee Han , Kyoung Soo Kim
发明人： Gun Byum Park , Gwan Hee Han , Kyoung Soo Kim
IPC分类号： H04W12/08 , H04W48/02
CPC分类号： H04W12/08 , H04W48/02 , H04W84/12
摘要： A security method in a physical layer and a wireless communication system using the same are provided. A wireless communication Access Point (AP) whose security has been enhanced in the physical layer includes a storage unit that manages channel bandwidth pattern data, a controller for sequentially acquiring channel bandwidth data from the channel bandwidth pattern data, a PLL controller for changing a channel bandwidth based on the acquired channel bandwidth data, and a wireless interface unit for performing wireless communication with a wireless communication terminal using the changed channel bandwidth. The channel bandwidth pattern data is identical to channel bandwidth pattern data stored in the wireless communication terminal, and the wireless communication terminal and the wireless communication AP are synchronized with each other such that the wireless communication terminal and the wireless communication AP perform wireless communication using the same channel bandwidth.
摘要翻译：提供了物理层中的安全方法和使用该方法的无线通信系统。其物理层的安全性已被增强的无线通信接入点（AP）包括：管理信道带宽模式数据的存储单元，用于从信道带宽模式数据顺序地获取信道带宽数据的控制器，用于改变信道的PLL控制器基于获取的信道带宽数据的带宽，以及用于使用改变的信道带宽与无线通信终端进行无线通信的无线接口单元。信道带宽模式数据与存储在无线通信终端中的信道带宽模式数据相同，无线通信终端和无线通信AP彼此同步，使得无线通信终端和无线通信AP使用相同的通道带宽。

9. 发明授权

US07119229B2 Alkaloid derivative and a pharmaceutical composition containing the same 有权
标题翻译：生物碱衍生物和含有它们的药物组合物
公开(公告)号：US07119229B2
公开(公告)日：2006-10-10
申请号：US10479057
申请日：2002-05-27
申请人： Wan Joo Kim , Kyoung Soo Kim , Myung Hwa Kim , Jong Yek Park , Jung Min Jang , Jae Won Choi , Dong Hoo Kim
发明人： Wan Joo Kim , Kyoung Soo Kim , Myung Hwa Kim , Jong Yek Park , Jung Min Jang , Jae Won Choi , Dong Hoo Kim
IPC分类号： C07C233/05 , A61K31/165
CPC分类号： C07C69/78 , C07C49/755 , C07C203/10 , C07C233/32 , C07C233/41 , C07C233/76 , C07C235/14 , C07C235/42 , C07C271/24 , C07C323/41 , C07C323/42 , C07C2603/34 , C07D307/93
摘要： Colchicine derivatives represented by the formula (I) with a halogen or nitric ester group, or pharmaceutically acceptable salts thereof, are described. Pharmaceutical compositions containing the same as effective components are also described. The colchicine derivatives were found to have anticancer, anti-proliferous and immunosuppressive function. Methods for preparing the colchicines derivatives are also provided.
摘要翻译：描述了由式（I）表示的秋水仙碱衍生物与卤素或硝酸酯基或其药学上可接受的盐。还描述了含有与有效成分相同的药物组合物。发现秋水仙素衍生物具有抗癌，抗增殖和免疫抑制功能。还提供了制备秋水仙碱衍生物的方法。

10. 发明授权

US06935048B2 Device for supporting burner and dryer with the same 失效
标题翻译：用于支持燃烧器和烘干机的设备
公开(公告)号：US06935048B2
公开(公告)日：2005-08-30
申请号：US10415494
申请日：2002-09-04
申请人： Soo Won Park , Kyoung Soo Kim
发明人： Soo Won Park , Kyoung Soo Kim
IPC分类号： F23C5/02 , D06F58/02 , D06F58/26 , F26B21/00
CPC分类号： D06F58/263
摘要： A device for supporting a burner (20) and a dryer having the same are disclosed, in which a structure for supporting the burner is simplified, thereby decreasing the manufacturing price and fabricating of the device is easy. The device for supporting the burner includes a base (70), a burner generating a hot air, a support member (60) having a main connecting part provided between the base and the burner for being detachably inserted to the base so as to support the burner.
摘要翻译：公开了一种用于支撑燃烧器（20）和具有该燃烧器的干燥器的装置，其中简化了用于支撑燃烧器的结构，从而降低了制造价格并且容易地制造该装置。用于支撑燃烧器的装置包括基座（70），产生热空气的燃烧器，支撑构件（60），其具有设置在基座和燃烧器之间的主连接部分，用于可拆卸地插入到基座中，以支撑刻录机。

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