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1. 发明授权

US06287440B1 Method for eliminating gas blocking in electrokinetic pumping systems 有权
标题翻译：在动力泵送系统中消除气体阻塞的方法
公开(公告)号：US06287440B1
公开(公告)日：2001-09-11
申请号：US09336535
申请日：1999-06-18
申请人： Don W. Arnold , Phillip H. Paul , Joseph S. Schoeniger
发明人： Don W. Arnold , Phillip H. Paul , Joseph S. Schoeniger
IPC分类号： B01D5702
CPC分类号： F04B53/06 , F04B19/006
摘要： A method for eliminating gas bubble blockage of current flow during operation of an electrokinetic pump. By making use of the ability to modify the surface charge on the porous dielectric medium used in electrokinetic pumps, it becomes possible to place electrodes away from the pressurized region of the electrokinetic pump. While gas is still generated at the electrodes they are situated such that the generated gas can escape into a larger buffer reservoir and not into the high pressure region of the pump where the gas bubbles can interrupt current flow. Various combinations of porous dielectric materials and ionic conductors can be used to create pumps that have desirable electrical, material handling, and flow attributes.
摘要翻译：一种在电动泵运行过程中消除气流阻塞电流的方法。通过利用在电动泵中使用的多孔介电介质上的表面电荷的修饰能力，可以将电极放置在电动泵的加压区域之外。虽然在电极处仍然产生气体，但是它们被定位成使得所产生的气体可以逸出到更大的缓冲容器中，而不会进入泵的高压区域，在该高压区域中气泡可以中断电流。可以使用多孔介电材料和离子导体的各种组合来产生具有期望的电气，材料处理和流动属性的泵。

2. 发明授权

US06277257B1 Electrokinetic high pressure hydraulic system 有权
标题翻译：电动高压液压系统
公开(公告)号：US06277257B1
公开(公告)日：2001-08-21
申请号：US09271687
申请日：1999-03-18
申请人： Phillip H. Paul , David J. Rakestraw , Don W. Arnold , Kenneth R. Hencken , Joseph S. Schoeniger , David W. Neyer
发明人： Phillip H. Paul , David J. Rakestraw , Don W. Arnold , Kenneth R. Hencken , Joseph S. Schoeniger , David W. Neyer
IPC分类号： B01D6144
CPC分类号： G01N30/32 , F04B19/006 , G01N2030/285 , G01N2030/326
摘要： An electrokinetic high pressure hydraulic pump for manipulating fluids in capillary-based systems. The pump uses electro-osmotic flow to provide a high pressure hydraulic system, having no moving mechanical parts, for pumping and/or compressing fluids, for providing valve means and means for opening and closing valves, for controlling fluid flow rate, and manipulating fluid flow generally and in capillary-based systems (Microsystems), in particular. The compact nature of the inventive high pressure hydraulic pump provides the ability to construct a micro-scale or capillary-based HPLC system that fulfills the desire for small sample quantity, low solvent consumption, improved efficiency, the ability to run samples in parallel, and field portability. Control of pressure and solvent flow rate is achieved by controlling the voltage applied to an electrokinetic pump.
摘要翻译：一种电动高压液压泵，用于在毛细管系统中操纵流体。泵使用电渗流提供高压液压系统，没有移动的机械部件，用于泵送和/或压缩流体，用于提供阀装置和用于打开和关闭阀门的装置，用于控制流体流速和操纵流体特别是在毛细管系统（Microsystems）中通常流动。本发明的高压液压泵的紧凑特性提供构建基于微量或基于毛细管的HPLC系统的能力，其满足对小样品量，低溶剂消耗，提高的效率，并行运行样品的能力的需求，以及现场可携带性。通过控制施加到电动泵的电压来实现压力和溶剂流速的控制。

3. 发明授权

US06572749B1 Electrokinetic high pressure hydraulic system 有权
标题翻译：电动高压液压系统
公开(公告)号：US06572749B1
公开(公告)日：2003-06-03
申请号：US09912154
申请日：2001-07-23
申请人： Phillip H. Paul , David J. Rakestraw , Don W. Arnold , Kenneth R. Hencken , Joseph S. Schoeniger , David W. Neyer
发明人： Phillip H. Paul , David J. Rakestraw , Don W. Arnold , Kenneth R. Hencken , Joseph S. Schoeniger , David W. Neyer
IPC分类号： B05B500
CPC分类号： G01N30/32 , F04B19/006 , G01N2030/285 , G01N2030/326
摘要： An electrokinetic high pressure hydraulic pump for manipulating fluids in capillary-based system. The pump uses electro-osmotic flow to provide a high pressure hydraulic system, having no moving mechanical parts, for pumping and/or compressing fluids, for providing valve means and means for opening and closing valves, for controlling fluid flow rate, and manipulating fluid flow generally and in capillary-based systems (microsystems), in particular. The compact nature of the inventive high pressure hydraulic pump provides the ability to construct a micro-scale or capillary-based HPLC system that fulfills the desire for small sample quantity, low solvent consumption, improved efficiency, the ability to run samples in parallel, and field portability. Control of pressure and solvent flow rate is achieved by controlling the voltage applied to an electrokinetic pump.
摘要翻译：一种电动高压液压泵，用于在毛细管系统中操纵流体。泵使用电渗流提供高压液压系统，没有移动的机械部件，用于泵送和/或压缩流体，用于提供阀装置和用于打开和关闭阀门的装置，用于控制流体流速和操纵流体特别是在毛细管系统（微系统）中流动。本发明的高压液压泵的紧凑特性提供构建基于微量或基于毛细管的HPLC系统的能力，其满足对小样品量，低溶剂消耗，提高的效率，并行运行样品的能力的需求，以及现场可携带性。通过控制施加到电动泵的电压来实现压力和溶剂流速的控制。

4. 发明授权

US06960285B2 Electrokinetically pumped high pressure sprays 有权
标题翻译：电动泵送高压喷雾
公开(公告)号：US06960285B2
公开(公告)日：2005-11-01
申请号：US10260164
申请日：2002-09-30
申请人： Joseph S. Schoeniger , Phillip H. Paul , Luke Schoeniger
发明人： Joseph S. Schoeniger , Phillip H. Paul , Luke Schoeniger
IPC分类号： A61M37/00 , B05B5/00 , B05B5/025 , B05B5/16 , F04B17/00 , F04B19/00 , A61F13/00
CPC分类号： F04B17/00 , A61M37/00 , B05B5/00 , B05B5/025 , B05B5/1691 , F04B19/006
摘要： An electrokinetic pump capable of producing high pressure is combined with a nozzle having a submicron orifice to provide a high pressure spray device. Because of its small size, the device can be contained within medical devices such as an endoscope for delivering biological materials such as DNA, chemo therapeutic agents, or vaccines to tissues and cells.
摘要翻译：能够产生高压的电动泵与具有亚微米孔的喷嘴组合以提供高压喷射装置。由于其体积小，装置可以包含在诸如用于将生物材料如DNA，化学治疗剂或疫苗递送到组织和细胞的内窥镜的医疗装置中。

5. 发明授权

US06495015B1 Electrokinetically pumped high pressure sprays 有权
标题翻译：电动泵送高压喷雾
公开(公告)号：US06495015B1
公开(公告)日：2002-12-17
申请号：US09595799
申请日：2000-06-16
申请人： Joseph S. Schoeniger , Phillip H. Paul , Luke Schoeniger
发明人： Joseph S. Schoeniger , Phillip H. Paul , Luke Schoeniger
IPC分类号： B05B500
CPC分类号： F04B17/00 , A61M37/00 , B05B5/00 , B05B5/025 , B05B5/1691 , F04B19/006
摘要： An electrokinetic pump capable of producing high pressure is combined with a nozzle having a submicron orifice to provide a high pressure spray device. Because of its small size, the device can be contained within medical devices such as an endoscope for delivering biological materials such as DNA, chemo therapeutic agents, or vaccines to tissues and cells.
摘要翻译：能够产生高压的电动泵与具有亚微米孔的喷嘴组合以提供高压喷射装置。由于其体积小，装置可以包含在诸如用于将生物材料如DNA，化学治疗剂或疫苗递送到组织和细胞的内窥镜的医疗装置中。

6. 发明授权

US07927477B2 Precision flow control system 有权
标题翻译：精密流量控制系统
公开(公告)号：US07927477B2
公开(公告)日：2011-04-19
申请号：US12334375
申请日：2008-12-12
申请人： Phillip H. Paul , Jason E. Rehm , Don W. Arnold
发明人： Phillip H. Paul , Jason E. Rehm , Don W. Arnold
IPC分类号： G05B24/04
CPC分类号： G01N30/32 , B01D61/56 , G01N2030/324 , G01N2030/326 , G05D7/0694 , G05D11/132 , Y10T137/85978 , Y10T137/85986 , Y10T137/86027 , G01N30/34 , G01N2030/285
摘要： A precision flow controller is capable of providing a flow rate less than 100 microliters/minute and varying the flow rate in a prescribed manner that is both predictable and reproducible where the accuracy and precision of the flowrate is less than 5% of the flow rate. A plurality of variable pressure fluid supplies pump fluid through a single outlet. Flowmeters measure the flow rates and a controller compares the flow rates to desired flowrates and, if necessary, adjusts the plurality of variable pressure fluid supplies so that the variable pressure fluid supplies pump fluid at the desired flow rate. The variable pressure fluid supplies can be pneumatically driven.
摘要翻译：精密流量控制器能够提供小于100微升/分钟的流量，并以规定的方式改变流速，既可预测又可再现，其中流量的精度和精度小于流量的5％。多个可变压力流体通过单个出口泵送流体。流量计测量流量，并且控制器将流量与所需流量进行比较，并且如果需要，调整多个可变压力流体供应，使得可变压力流体以期望的流速供应泵流体。可变压力流体供应可以气动驱动。

7. 发明授权

US07559356B2 Electrokinetic pump driven heat transfer system 有权
标题翻译：电动泵驱动传热系统
公开(公告)号：US07559356B2
公开(公告)日：2009-07-14
申请号：US10827799
申请日：2004-04-19
申请人： Phillip H. Paul , Deon S. Anex , Don W. Arnold
发明人： Phillip H. Paul , Deon S. Anex , Don W. Arnold
IPC分类号： F28D15/00
CPC分类号： G06F1/20 , C02F1/02 , C02F2001/46128 , F04B19/006 , F28D15/00 , F28D15/0266 , F28F2250/08 , G06F2200/201
摘要： A heat transfer system comprising a primary heat exchanger for receiving heat from a heat source; a secondary heat exchanger for exhausting heat to a heat sink; a conduit connecting the primary heat exchanger and the secondary heat exchanger; and an electrokinetic pump for pumping a heat exchange fluid between the primary heat exchanger and the secondary heat exchanger through the conduit.
摘要翻译：一种传热系统，包括用于从热源接收热量的主热交换器; 用于将热量排放到散热器的二次热交换器; 连接主热交换器和二次热交换器的导管; 以及用于在主热交换器和次级热交换器之间通过导管泵送热交换流体的电动泵。

8. 发明申请

US20090090174A1 Precision Flow Control System 有权
标题翻译：精密流量控制系统
公开(公告)号：US20090090174A1
公开(公告)日：2009-04-09
申请号：US12334375
申请日：2008-12-12
申请人： Phillip H. Paul , Jason E. Rehm , Don W. Arnold
发明人： Phillip H. Paul , Jason E. Rehm , Don W. Arnold
IPC分类号： G01N30/32 , B01D35/14 , G05D7/06
CPC分类号： G01N30/32 , B01D61/56 , G01N2030/324 , G01N2030/326 , G05D7/0694 , G05D11/132 , Y10T137/85978 , Y10T137/85986 , Y10T137/86027 , G01N30/34 , G01N2030/285
摘要： A precision flow controller is capable of providing a flow rate less than 100 microliters/minute and varying the flow rate in a prescribed manner that is both predictable and reproducible where the accuracy and precision of the flowrate is less than 5% of the flow rate. A plurality of variable pressure fluid supplies pump fluid through a single outlet. Flowmeters measure the flow rates and a controller compares the flow rates to desired flowrates and, if necessary, adjusts the plurality of variable pressure fluid supplies so that the variable pressure fluid supplies pump fluid at the desired flow rate. The variable pressure fluid supplies can be pneumatically driven.
摘要翻译：精密流量控制器能够提供小于100微升/分钟的流量，并以规定的方式改变流速，既可预测又可再现，其中流量的精度和精度小于流量的5％。多个可变压力流体通过单个出口泵送流体。流量计测量流量，并且控制器将流量与所需流量进行比较，并且如果需要，调整多个可变压力流体供应，使得可变压力流体以期望的流速供应泵流体。可变压力流体供应可以气动驱动。

9. 发明授权

US07521140B2 Fuel cell system with electrokinetic pump 有权
标题翻译：带电动泵的燃料电池系统
公开(公告)号：US07521140B2
公开(公告)日：2009-04-21
申请号：US10827788
申请日：2004-04-19
申请人： Don W. Arnold , Phillip H. Paul , Deon S. Anex
发明人： Don W. Arnold , Phillip H. Paul , Deon S. Anex
IPC分类号： H01M8/02 , H01M8/04
CPC分类号： H01M8/04589 , H01M8/04007 , H01M8/04186 , H01M8/0432 , H01M8/04447 , H01M8/04753 , H01M8/0612
摘要： A fuel cell system having a fuel cell, the fuel cell having a membrane-electrode assembly; a fuel reservoir containing a liquid fuel; a conduit coupling the fuel reservoir to the fuel cell; and an electrokinetic fuel pump coupled to the conduit, the electrokinetic fuel pump having a plurality of electrodes; wherein the electrokinetic fuel pump moves fuel from the fuel reservoir through the conduit to the fuel cell; and wherein the electrokinetic fuel pump electrodes do not deleteriously affect the performance of the membrane-electrode assembly.
摘要翻译：一种具有燃料电池的燃料电池系统，所述燃料电池具有膜 - 电极组件; 包含液体燃料的燃料储存器; 将燃料储存器联接到燃料电池的导管; 以及耦合到所述导管的电动燃料泵，所述电动燃料泵具有多个电极; 其中所述电动燃料泵将燃料从所述燃料储存器通过所述导管移动到所述燃料电池; 并且其中所述电动燃料泵电极不会有害地影响所述膜 - 电极组件的性能。

10. 发明授权

US07175810B2 Processing of particles 有权
标题翻译：颗粒加工
公开(公告)号：US07175810B2
公开(公告)日：2007-02-13
申请号：US10849715
申请日：2004-05-19
申请人： Don W. Arnold , David J. Rakestraw , Phillip H. Paul , Patrick Pak-Ho Leung
发明人： Don W. Arnold , David J. Rakestraw , Phillip H. Paul , Patrick Pak-Ho Leung
IPC分类号： G01N33/48
CPC分类号： G01N21/05 , G01N15/1404 , G01N15/1459 , G01N21/64 , G01N27/447 , G01N33/54313 , G01N2015/1497 , G01N2021/0346 , G01N2035/00564 , Y10T436/2575
摘要： Particles dispersed in a liquid are assembled in a configuration in which all the particles lie in the same plane, and the assembled particles are processed while in that configuration. The assembled particles can for example be simultaneously exposed to electromagnetic radiation which elicits from the particles a response which provides information about the particles. The particles can for example be cells, cell fragments, or analyte-bearing beads of the type conventionally analyzed in a cytometer.
摘要翻译：分散在液体中的颗粒以其中所有颗粒位于相同平面中的构型组装，并且组装的颗粒在该构造中被处理。组装的颗粒可以例如同时暴露于从颗粒引起的电磁辐射，该响应提供关于颗粒的信息。颗粒可以例如是在细胞计数器中常规分析的类型的细胞，细胞碎片或分析物携带珠。

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