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    • 2. 发明授权
    • Process for the production of dextran polymers of controlled molecular
size and molecular size distributions
    • 生产具有受控分子大小和分子大小分布的葡聚糖聚合物的方法
    • US5229277A
    • 1993-07-20
    • US664755
    • 1991-03-05
    • Donal F. DayDoman Kim
    • Donal F. DayDoman Kim
    • C12N9/44C12P19/08
    • C12R1/645C12N9/2454C12P19/08
    • A process for the production of dextran polymers of controlled average number molecular weight sizes, and molecular weight size distributions via the mixed culture fermentation of Leuconostoc mesenteroides and a constitutive mutant microorganism capable of elaborating the enzyme dextranase, particularly Lipomyces starkeyi ATCC 74054, in the presence of sucrose. The Leuconostoc mesenteroides produces the dextran polymer, and the mutant Lipomyces starkeyi ATCC 74054 concurrently produces dextranase, an enzyme whose activity reduces the size of the dextran polymers and permits their growth or reduction in molecular weight size in direct relation to the temperature and time period regimen imposed as conditions for the reactions.
    • 生产具有受控平均数分子量大小的葡聚糖聚合物的方法,以及通过混合培养发酵明串珠菌肠炎的组合型突变体微生物和能够精制葡聚糖酶的组成型突变体微生物,特别是脂多糖分枝杆菌ATCC 74054的分子量大小分布的方法, 的蔗糖。 明串珠菌肠胃菌产生葡聚糖聚合物,并且突变体Lipomyces starkeyi ATCC 74054同时产生葡聚糖酶,其活性降低葡聚糖聚合物的大小并允许其与温度和时间段方案直接相关的分子量大小的生长或降低 作为反应的条件。