专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08394783B2 Polysaccharide gel formulation having multi-stage bioactive agent delivery 有权
公开(公告)号：US08394783B2
公开(公告)日：2013-03-12
申请号：US13439566
申请日：2012-04-04
申请人： Dimitrios Stroumpoulis , Dustin Leslie , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Dustin Leslie , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/70
CPC分类号： A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K9/0024 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/12 , A61K47/36 , A61K2800/522 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J3/12 , C08J3/128 , C08J3/24 , C08J2351/02 , C08K5/0025 , C08L1/02 , C08L5/04 , C08L5/08 , C08L5/10
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide.

2. 发明申请

US20100098764A1 POLYSACCHARIDE GEL FORMULATION HAVING MULTI-STAGE BIOACTIVE AGENT DELIVERY 有权
标题翻译：具有多阶段生物交换剂的多糖凝胶配方
公开(公告)号：US20100098764A1
公开(公告)日：2010-04-22
申请号：US12616020
申请日：2009-11-10
申请人： Dimitrios STROUMPOULIS , Dustin B. Leslie , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios STROUMPOULIS , Dustin B. Leslie , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/726 , A61K9/14 , A61K31/235 , A61K31/165
CPC分类号： A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K9/0024 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/12 , A61K47/36 , A61K2800/522 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J3/12 , C08J3/128 , C08J3/24 , C08J2351/02 , C08K5/0025 , C08L1/02 , C08L5/04 , C08L5/08 , C08L5/10
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。

3. 发明申请

US20120189699A1 POLYSACCHARIDE GEL FORMULATION HAVING MULTI-STAGE BIOACTIVE AGENT DELIVERY 有权
标题翻译：具有多阶段生物交换剂的多糖凝胶配方
公开(公告)号：US20120189699A1
公开(公告)日：2012-07-26
申请号：US13439566
申请日：2012-04-04
申请人： Dimitrios Stroumpoulis , Dustin B. Leslie , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Dustin B. Leslie , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K9/14 , A61P23/00 , A61K31/737
CPC分类号： A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K9/0024 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/12 , A61K47/36 , A61K2800/522 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J3/12 , C08J3/128 , C08J3/24 , C08J2351/02 , C08K5/0025 , C08L1/02 , C08L5/04 , C08L5/08 , C08L5/10
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。

4. 发明授权

US08513216B2 Polysaccharide gel formulation having increased longevity 有权
公开(公告)号：US08513216B2
公开(公告)日：2013-08-20
申请号：US12558270
申请日：2009-09-11
申请人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/70
CPC分类号： A61L27/26 , A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/183 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K2800/522 , A61L27/505 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08K5/053 , C08L5/08 , C08L2205/02
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.

5. 发明授权

US08394784B2 Polysaccharide gel formulation having multi-stage bioactive agent delivery 有权
标题翻译：具有多级生物活性剂递送的多糖凝胶制剂
公开(公告)号：US08394784B2
公开(公告)日：2013-03-12
申请号：US12616020
申请日：2009-11-10
申请人： Dimitrios Stroumpoulis , Dustin B. Leslie , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Dustin B. Leslie , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A01N43/04 , C07H1/00
CPC分类号： A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K9/0024 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/12 , A61K47/36 , A61K2800/522 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J3/12 , C08J3/128 , C08J3/24 , C08J2351/02 , C08K5/0025 , C08L1/02 , C08L5/04 , C08L5/08 , C08L5/10
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。

6. 发明授权

US08394782B2 Polysaccharide gel formulation having increased longevity 有权
标题翻译：多糖凝胶配方寿命延长
公开(公告)号：US08394782B2
公开(公告)日：2013-03-12
申请号：US12276167
申请日：2008-11-21
申请人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/70
CPC分类号： A61L27/26 , A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/183 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K2800/522 , A61L27/505 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08K5/053 , C08L5/08 , C08L2205/02
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。在一些实施方案中，掺入步骤包括：1）以高水合状态将至少一种抑制剂与至少一种多糖混合，从而将至少一种抑制剂包封在多糖网络中，和2）使多糖网络脱水从而控制释放动力学或最终膨胀比。在另一个实施方案中，掺入步骤包括：1）将至少一种抑制剂包封在生物相容性或可生物降解的容器中，和2）将多糖和血管结合成凝胶制剂。本文所述的多糖凝胶制剂可用于各种化妆品应用。

7. 发明申请

US20100004198A1 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY 有权
标题翻译：多糖凝胶配方具有增加的长度
公开(公告)号：US20100004198A1
公开(公告)日：2010-01-07
申请号：US12558270
申请日：2009-09-11
申请人： Dimitrios STROUMPOULIS , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios STROUMPOULIS , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/715 , A61K31/717 , A61K31/722 , A61K31/721 , A61K31/727 , A61K31/728
CPC分类号： A61L27/26 , A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/183 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K2800/522 , A61L27/505 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08K5/053 , C08L5/08 , C08L2205/02
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。在一些实施方案中，掺入步骤包括：1）以高水合状态将至少一种抑制剂与至少一种多糖混合，从而将至少一种抑制剂包封在多糖网络中，和2）使多糖网络脱水从而控制释放动力学或最终膨胀比。在另一个实施方案中，掺入步骤包括：1）将至少一种抑制剂包封在生物相容性或可生物降解的容器中，和2）将多糖和血管结合成凝胶制剂。本文所述的多糖凝胶制剂可用于各种化妆品应用。

8. 发明申请

US20090143331A1 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY 有权
标题翻译：多糖凝胶配方具有增加的长度
公开(公告)号：US20090143331A1
公开(公告)日：2009-06-04
申请号：US12276167
申请日：2008-11-21
申请人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Christopher S. Mudd , Ahmet Tezel
IPC分类号： A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737
CPC分类号： A61L27/26 , A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/183 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K2800/522 , A61L27/505 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08K5/053 , C08L5/08 , C08L2205/02
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。在一些实施方案中，掺入步骤包括：1）以高水合状态将至少一种抑制剂与至少一种多糖混合，从而将至少一种抑制剂包封在多糖网络中，以及2）使多糖网络脱水从而控制释放动力学或最终膨胀比。在另一个实施方案中，掺入步骤包括：1）将至少一种抑制剂包封在生物相容性或可生物降解的容器中，和2）将多糖和血管结合成凝胶制剂。本文所述的多糖凝胶制剂可用于各种化妆品应用。

9. 发明申请

US20090036403A1 Tunably Crosslinked Polysaccharide Compositions 失效
标题翻译：可交联的多糖组合物
公开(公告)号：US20090036403A1
公开(公告)日：2009-02-05
申请号：US12178574
申请日：2008-07-23
申请人： Dimitrios Stroumpoulis , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Ahmet Tezel
IPC分类号： A61K31/728 , A61P17/00 , A61K8/73 , A61Q19/00
CPC分类号： C08B37/0072 , A61L27/20 , A61L2430/34 , C08L5/08
摘要： The present invention generally relates to novel biocompatible crosslinked polysaccharide gel compositions, methods of their manufacture and use, and the novel crosslinkers used to make them. In one aspect of the invention, a novel polyethylene glycol crosslinking agent is described for crosslinking hyaluronic acid. In another aspect of the invention, novel crosslinking agents comprising more than two functional groups are described. These multifunctional crosslinking agents can be used on their own to crosslink hyaluronic acid, or they may be combined with bifunctional crosslinking agents in varying ratios to make hyaluronic acid of tunable mechanical strength and hardness. The present invention also discloses novel hyaluronic acid compositions that have been coated with polyethylene glycol and methods of their use.
摘要翻译：本发明一般涉及新的生物相容性交联多糖凝胶组合物，其制造和使用方法，以及用于制备它们的新型交联剂。在本发明的一个方面，描述了用于交联透明质酸的新型聚乙二醇交联剂。在本发明的另一方面，描述了包含多于两个官能团的新型交联剂。这些多功能交联剂可以单独使用以交联透明质酸，或者它们可以以不同比例与双功能交联剂组合，以使透明质酸具有可调节的机械强度和硬度。本发明还公开了已经涂覆有聚乙二醇的新型透明质酸组合物及其使用方法。

10. 发明授权

US08318695B2 Tunably crosslinked polysaccharide compositions 失效
标题翻译：可交联的多糖组合物
公开(公告)号：US08318695B2
公开(公告)日：2012-11-27
申请号：US12178574
申请日：2008-07-23
申请人： Dimitrios Stroumpoulis , Ahmet Tezel
发明人： Dimitrios Stroumpoulis , Ahmet Tezel
IPC分类号： A61K31/715
CPC分类号： C08B37/0072 , A61L27/20 , A61L2430/34 , C08L5/08
摘要： The present invention generally relates to novel biocompatible crosslinked polysaccharide gel compositions, methods of their manufacture and use, and the novel crosslinkers used to make them. In one aspect of the invention, a novel polyethylene glycol crosslinking agent is described for crosslinking hyaluronic acid. In another aspect of the invention, novel crosslinking agents comprising more than two functional groups are described. These multifunctional crosslinking agents can be used on their own to crosslink hyaluronic acid, or they may be combined with bifunctional crosslinking agents in varying ratios to make hyaluronic acid of tunable mechanical strength and hardness. The present invention also discloses novel hyaluronic acid compositions that have been coated with polyethylene glycol and methods of their use.
摘要翻译：本发明一般涉及新的生物相容性交联多糖凝胶组合物，其制造和使用方法，以及用于制备它们的新型交联剂。在本发明的一个方面，描述了用于交联透明质酸的新型聚乙二醇交联剂。在本发明的另一方面，描述了包含多于两个官能团的新型交联剂。这些多功能交联剂可以单独使用以交联透明质酸，或者它们可以以不同比例与双功能交联剂组合，以使透明质酸具有可调节的机械强度和硬度。本发明还公开了已经涂覆有聚乙二醇的新型透明质酸组合物及其使用方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式