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1. 发明授权

US5653109A Annular combustor with fuel manifold 失效
标题翻译：带燃油歧管的环形燃烧器
公开(公告)号：US5653109A
公开(公告)日：1997-08-05
申请号：US597990
申请日：1996-02-07
申请人： Dennis L. Overton , Leighton Jones
发明人： Dennis L. Overton , Leighton Jones
IPC分类号： F02C7/22 , F23R3/10 , F23R3/28 , F23R3/50 , F23R3/34
CPC分类号： F23R3/283 , F02C7/222 , F23R3/10 , F23R3/50 , F05D2220/327 , F05D2260/20 , Y02T50/676
摘要： An annular combustor structure particularly suited to staged combustion has a faired centrebody incorporating a diffuser in the head of the combustor. The structure carries fuel injector mountings for pilot and main stage combustion which receive fuel from respective manifolds running around the hollow interior of the structure. There are two annular chambers each containing a fuel manifold, and cooling air passes through the chambers before entering the combustion volume. The manifolds are connected to an external source of fuel by conduits which pass radially through the combustion chamber outer casing walls.
摘要翻译：特别适用于分级燃烧的环形燃烧器结构具有在燃烧器的头部中并入扩散器的流线型中心体。该结构承载用于先导和主级燃烧的燃料喷射器安装件，其从围绕结构的中空内部运行的相应歧管接收燃料。存在两个环形室，每个环形室包含燃料歧管，并且冷却空气在进入燃烧体积之前通过室。歧管通过径向通过燃烧室外壳壁的导管连接到外部燃料源。

2. 发明申请

US20130225692A1 FORMULATIONS COMPRISING POLYETHYLENE GLYCOL 审中-公开
标题翻译：包含聚乙烯甘油的制剂
公开(公告)号：US20130225692A1
公开(公告)日：2013-08-29
申请号：US13883153
申请日：2011-11-04
申请人： Peter Stein , Leighton Jones , Samuel Smith , Ian Cox , Jörg Plessl
发明人： Peter Stein , Leighton Jones , Samuel Smith , Ian Cox , Jörg Plessl
IPC分类号： A61K31/08
CPC分类号： A61K31/77 , A61K9/0053 , A61K9/0056 , A61K9/2018 , A61K9/2031 , A61K31/08 , A61K47/10 , A61K47/12 , A61K47/26 , A61K47/36
摘要： The present invention concerns a solid formulation for oral administration as a solid comprising polyethylene glycol and a further solid such as mannitol. The formulation may be used to prevent gastrointestinal disorders such as constipation in healthy subjects. In some embodiments, the solid formulation is chewable or suckable.
摘要翻译：本发明涉及一种用于口服给药的固体制剂，其为包含聚乙二醇和另外的固体如甘露醇的固体。该制剂可用于预防健康受试者的胃肠道疾病如便秘。在一些实施方案中，固体制剂是可咀嚼或可吸收的。

3. 发明申请

US20130216493A1 PEG OR PEG BLOCK COPOLYMERS FOR TREATING COLORECTAL CANCER 审中-公开
标题翻译：用于治疗彩色癌症的PEG或PEG嵌段共聚物
公开(公告)号：US20130216493A1
公开(公告)日：2013-08-22
申请号：US13883262
申请日：2011-11-04
申请人： Peter Stein , Leighton Jones , Samuel Smith , Ian Cox , Jörg Plessl , Corinne De Vries , Rachel Charlton
发明人： Peter Stein , Leighton Jones , Samuel Smith , Ian Cox , Jörg Plessl , Corinne De Vries , Rachel Charlton
IPC分类号： A61K31/765
CPC分类号： A61K31/77 , A61K9/2013 , A61K9/2018 , A61K9/2031 , A61K31/765
摘要： The present invention relates to methods for and of treating, ameliorating or preventing colorectal cancer (CRC) in humans using polyethylene glycol (PEG) or a PEG block-copolymer such as Pluronic® F68. Compositions for use in treating, ameliorating and/or preventing CRC comprising PEG are also disclosed. Such compositions may be used in the methods of the invention.
摘要翻译：本发明涉及使用聚乙二醇（PEG）或PEG嵌段共聚物如Pluronic F68来治疗，改善或预防人类结肠直肠癌（CRC）的方法。还公开了用于治疗，改善和/或预防包含PEG的CRC的组合物。这些组合物可用于本发明的方法中。

4. 发明授权

US07482452B2 Process for preparing 3-aminothienopyridone derivatives 失效
标题翻译：制备3-氨基噻吩并吡啶衍生物的方法
公开(公告)号：US07482452B2
公开(公告)日：2009-01-27
申请号：US10561051
申请日：2004-06-18
申请人： Graham Robert Evans , Ian Harold Smith , Neil Tremayne , Leighton Jones , Marianne Langston
发明人： Graham Robert Evans , Ian Harold Smith , Neil Tremayne , Leighton Jones , Marianne Langston
IPC分类号： C07D471/02 , C07D491/02 , C07D498/02 , C07D513/02 , C07D515/02
CPC分类号： C07D495/04 , C07D213/85
摘要： This invention provides a class of 3-amino-7H-thieno[2,3-b]pyridin-6-one derivatives, substituted in the 7-position by an aryl, heteroaryl, cycloalkyl or heterocycloalkyl moiety, and in the 2-position by a specified range of substituent groups; also provided is a process for preparing those compounds, and the use thereof as intermediates in the manufacture of certain p38 MAP kinase inhibitors.
摘要翻译：本发明提供一类3-位氨基-7H-噻吩并[2,3-b]吡啶-6-酮衍生物，其在7-位被芳基，杂芳基，环烷基或杂环烷基部分取代，并且在2-位上通过指定范围的取代基; 还提供了制备这些化合物的方法，以及作为制备某些p38MAP激酶抑制剂的中间体的用途。

5. 发明申请

US20070191608A1 Process for preparing 3-aminothienopyridone derivatives 失效
标题翻译：制备3-氨基噻吩并吡啶衍生物的方法
公开(公告)号：US20070191608A1
公开(公告)日：2007-08-16
申请号：US10561051
申请日：2004-06-18
申请人： Graham Evans , Ian Smith , Neil Tremayne , Leighton Jones , Marianne Langston
发明人： Graham Evans , Ian Smith , Neil Tremayne , Leighton Jones , Marianne Langston
IPC分类号： C07D471/02 , C07D213/63
CPC分类号： C07D495/04 , C07D213/85
摘要： This invention provides a class of 3-amino-7H-thieno[2,3-b]pyridin-6-one derivatives, substituted in the 7-position by an aryl, heteroaryl, cycloalkyl or heterocycloalkyl moiety, and in the 2-position by a specified range of substituent groups; also provided is a process for preparing those compounds, and the use thereof as intermediates in the manufacture of certain p38 MAP kinase inhibitors.
摘要翻译：本发明提供一类3-位氨基-7H-噻吩并[2,3-b]吡啶-6-酮衍生物，其在7-位被芳基，杂芳基，环烷基或杂环烷基部分取代，并且在2-位上通过指定范围的取代基; 还提供了制备这些化合物的方法，以及作为制备某些p38MAP激酶抑制剂的中间体的用途。

6. 发明授权

US5737921A Gas turbine engine fuel injector 失效
标题翻译：燃气轮机发动机燃油喷射器
公开(公告)号：US5737921A
公开(公告)日：1998-04-14
申请号：US425401
申请日：1995-04-20
申请人： Leighton Jones , John S. Richardson
发明人： Leighton Jones , John S. Richardson
IPC分类号： F23C7/02 , F23D11/10 , F23M5/08 , F23R3/14 , F23R3/10
CPC分类号： F23M5/085 , F23C7/02 , F23D11/107 , F23R3/14 , F23D2900/11101 , F23R2900/03041 , Y02T50/675
摘要： A multi-stream fuel injector for a gas turbine engine comprises a plurality of concentric member which define a plurality of flow passages carrying HP compressor air or fuel/air mixture. One of the members is formed with a wide-angle, frusto-conical flared lip to propagate a wide-angle fuel/air mixture cone in the combustion region. The lip is of such a cross-sectional configuration that air flowing over the lip surface remains attached to the surface and flows in a non-turbulent manner, initially in a radially inward direction, and subsequently in a radially outward direction. The lip ensures that undesirable regions of recirculation are avoided around the fuel injector.
摘要翻译：用于燃气涡轮发动机的多流燃料喷射器包括多个同心构件，其限定承载HP压缩机空气或燃料/空气混合物的多个流动通道。其中一个构件形成有广角的截头圆锥形的喇叭口，以在燃烧区域中传播广角燃料/空气混合物锥体。唇缘具有这样的横截面构造，使得流过唇表面的空气保持附着在表面上，并且以非湍流方式，最初在径向向内的方向上，随后沿径向向外的方向流动。该唇缘确保在燃料喷射器周围避免不需要的再循环区域。

7. 发明授权

US5609031A Combustor assembly 失效
标题翻译：燃烧器总成
公开(公告)号：US5609031A
公开(公告)日：1997-03-11
申请号：US567587
申请日：1995-12-05
申请人： Leighton Jones
发明人： Leighton Jones
IPC分类号： B21K25/00 , F23R3/10 , F23R3/50 , F23R3/60 , F02C1/00
CPC分类号： B21K25/00 , F23R3/10 , F23R3/50 , F23R3/60 , B23P2700/13 , F05B2260/30
摘要： Gas turbine engine combustor designs are tending to higher operating temperatures and, therefore, utilisation of high temperature materials such as, for example, ceramics, composite material and high temperature nickel alloys. However use of these materials for combustor components leads, in turn, to problems of how to join together those components. A high temperature material combustor barrel and a similar combustor head heatshield are joined to a metal or metal alloy combustor head by means of a lip around the circumference of the head swaged or rolled onto a lip on the barrel trapping the heatshield between them.
摘要翻译：燃气涡轮发动机燃烧器设计趋向于更高的操作温度，并因此利用高温材料，例如陶瓷，复合材料和高温镍合金。然而，这些材料用于燃烧器部件的方式又导致如何将这些部件连接在一起的问题。高温材料燃烧器筒和类似的燃烧器头部散热器通过围绕头部圆周的唇缘连接到金属或金属合金燃烧器头部，该头部围绕着头部的圆周，或者滚动到桶上的唇部上，从而在它们之间捕获遮挡物。

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