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1. 发明授权

US08608850B1 Low-energy, hydrogen-free method of diamond synthesis 失效
标题翻译：低能量，无氢的金刚石合成方法
公开(公告)号：US08608850B1
公开(公告)日：2013-12-17
申请号：US12689224
申请日：2010-01-18
申请人： Deepak Varshney , Gerardo Morell , Brad R. Weiner , Vladimir Makarov
发明人： Deepak Varshney , Gerardo Morell , Brad R. Weiner , Vladimir Makarov
IPC分类号： C30B29/04
CPC分类号： C23C14/24 , C23C14/0611 , C30B23/00 , C30B29/04
摘要： Diamond thin films were deposited on copper substrate by the Vapor Solid (VS) deposition method using a mixture of fullerene C60 and graphite as the source material. The deposition took place only when the substrate was kept in a narrow temperature range of approximately 550-650° C. Temperatures below and above this range results in the deposition of fullerenes and other carbon compounds, respectively.
摘要翻译：通过使用富勒烯C60和石墨的混合物作为源材料的蒸汽固体（VS）沉积方法将金刚石薄膜沉积在铜基底上。只有当基板保持在约550-650℃的窄温度范围内时才发生沉积。低于和高于该范围的温度分别导致富勒烯和其它碳化合物的沉积。

2. 发明授权

US09931609B1 Antibacterial activity of silver-graphene quantum dots nanocomposites against gram-positive and gram-negative bacteria 有权
公开(公告)号：US09931609B1
公开(公告)日：2018-04-03
申请号：US15096235
申请日：2016-04-11
申请人： Khaled Habiba , Vladimir Makarov , Brad R Weiner , Gerardo Morell
发明人： Khaled Habiba , Vladimir Makarov , Brad R Weiner , Gerardo Morell
IPC分类号： B82Y5/00 , B01J19/12 , A61K33/38 , A61K47/48 , B82Y40/00
CPC分类号： B01J19/121 , A61K33/38 , A61K47/48215 , A61K47/48884 , B82Y5/00 , B82Y40/00 , Y10S977/734 , Y10S977/847 , Y10S977/915
摘要： The invention provides a composite of silver nanoparticles decorated with graphene quantum dots (Ag-GQDs) using pulsed laser synthesis. The nanocomposites were functionalized with polyethylene glycol (PEG). A concentration of 150 μg/mL of Ag-GQDs, a non-toxic level for human cells, exhibits strong antibacterial activity against both Gram-Positive and Gram-Negative Bacteria.

3. 发明授权

US08491964B1 Diamond nucleation using polyethene 失效
标题翻译：使用聚乙烯的金刚石成核
公开(公告)号：US08491964B1
公开(公告)日：2013-07-23
申请号：US13070214
申请日：2011-03-23
申请人： Gerardo Morell , Vladimir Makarov , Deepak Varshney , Brad Weiner
发明人： Gerardo Morell , Vladimir Makarov , Deepak Varshney , Brad Weiner
IPC分类号： C23C16/27
CPC分类号： C23C16/272
摘要： The invention presents a simple, non-destructive and non-abrasive method of diamond nucleation using polyethene. It particularly describes the nucleation of diamond on an electrically viable substrate surface using polyethene via chemical vapor deposition (CVD) technique in a gaseous environment.
摘要翻译：本发明提出了使用聚乙烯的金刚石成核的简单的，非破坏性和非研磨性的方法。它特别描述了在气体环境中通过化学气相沉积（CVD）技术使用聚乙烯在电存活的基底表面上金刚石的成核。

4. 发明授权

US09533882B1 Diamond-like carbon nanorods and fabrication thereof 有权
标题翻译：类金刚石碳纳米棒及其制造
公开(公告)号：US09533882B1
公开(公告)日：2017-01-03
申请号：US13070678
申请日：2011-03-24
申请人： Deepak Varshney , Vladimir Makarov , Gerardo Morell , Puja Saxena , Brad Weiner
发明人： Deepak Varshney , Vladimir Makarov , Gerardo Morell , Puja Saxena , Brad Weiner
IPC分类号： B01J20/28 , B82Y30/00 , C01B31/02 , D01F9/127
CPC分类号： B82Y30/00 , B01J20/28028 , B01J2203/0655 , C01B32/05 , D01F9/127
摘要： Novel sp3 rich diamond-like carbon (DLC) nanorod films were fabricated by hot filament chemical vapor deposition technique. The results are indicative of a bottom-up self-assembly synthesis process, which results in a hierarchical structure that consists of microscale papillae comprising numerous nanorods. The papillae have diameters ranging from 2 to 4 μm and the nanorods have diameters in the 35-45 nm range. A growth mechanism based on the vapor liquid-solid mechanism is proposed that accounts for the morphological aspects in the micro- and nano-scales.
摘要翻译：通过热丝化学气相沉积技术制备了新型富含三氧化三铁的碳纳米棒（DLC）纳米棒。结果表明自下而上的自组装合成过程，其结果是由包括许多纳米棒的微乳头组成的层次结构。乳头的直径范围为2至4μm，纳米棒的直径范围为35-45nm。提出了一种基于蒸汽液 - 固体机制的生长机制，其解释了微尺度和纳米尺度的形态方面。

5. 发明授权

US08889350B2 Methods and compositions for isolating polynucleotides 有权
标题翻译：用于分离多核苷酸的方法和组合物
公开(公告)号：US08889350B2
公开(公告)日：2014-11-18
申请号：US13073781
申请日：2011-03-28
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04 , C07H21/00
CPC分类号： C12Q1/6806 , C12Q1/6813 , C12Q1/6816 , C12Q1/682 , C12Q1/6827 , C12Q1/683 , C12Q1/6844 , C12Q1/6846 , C12Q1/686 , C12Q1/6862 , C12Q1/6869 , C12Q1/6876 , C12Q2525/119 , C12Q2525/151 , C12Q2525/161 , C12Q2563/149 , C12Q2531/125 , C12Q2563/131 , C12Q2537/159
摘要： Methods of isolating target double-stranded polynucleotides with internal single-stranded regions are provided. Compositions and kits comprising double-stranded polynucleotides with internal single-stranded regions are also provided.
摘要翻译：提供了用内部单链区域分离靶双链多核苷酸的方法。还提供了包含具有内部单链区域的双链多核苷酸的组合物和试剂盒。

6. 发明授权

US08555267B2 Performing register allocation of program variables based on priority spills and assignments 有权
标题翻译：基于优先级溢出和分配执行程序变量的寄存器分配
公开(公告)号：US08555267B2
公开(公告)日：2013-10-08
申请号：US12717042
申请日：2010-03-03
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： G06F9/45
摘要： A mechanism for performing register allocation based on priority spills and assignments is disclosed. A method of embodiments of the invention includes repetitively detecting fat points during a compilation process of a software program running on a virtual machine of a computer system, each fat point representing a program point having a high register pressure, the high register pressure occurs when a number of live program variables of the software program living at a given program point of the software program is greater than a number of available processor registers of the computer system. The method further includes choosing a fat point with a highest register pressure, selecting a live program variable having a lowest priority at the chosen fat point, and spilling the lowest priority live program variable to memory of the computer system.
摘要翻译：公开了一种基于优先溢出和分配进行寄存器分配的机制。本发明实施例的方法包括在计算机系统的虚拟机上运行的软件程序的编译过程中重复检测脂肪点，每个脂肪点表示具有高登记压力的程序点，当高生活在软件程序的给定程序点的软件程序的实际程序变量的数量大于计算机系统的可用处理器寄存器的数量。该方法还包括选择具有最高注册压力的脂肪点，选择在所选脂肪点具有最低优先级的实况节目变量，以及将最低优先级的实时节目变量溢出到计算机系统的存储器。

7. 发明申请

US20110129832A1 Polynucleotide Primers and Probes 审中-公开
标题翻译：多核苷酸引物和探针
公开(公告)号：US20110129832A1
公开(公告)日：2011-06-02
申请号：US12913742
申请日：2010-10-27
申请人： Vladimir Makarov , Sergey V. Chupreta
发明人： Vladimir Makarov , Sergey V. Chupreta
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6876 , C12Q1/6818 , C12Q1/6832 , C12Q2525/161 , C12Q2537/125 , C12Q2537/1373 , C12Q2537/163 , C12Q2525/121 , C12Q2525/301
摘要： The present invention provides a novel technology that involves improved primer design. These primer pairs have a wide range of applications and provide high sensitivity and specificity.
摘要翻译：本发明提供一种涉及改进底漆设计的新技术。这些引物对具有广泛的应用范围，提供高灵敏度和特异性。

8. 发明申请

US20100083407A1 NUCLEOTIDE SEQUENCES AND POLYPEPTIDES ENCODED THEREBY USEFUL FOR MODIFYING PLANT CHARACTERISTICS 审中-公开
公开(公告)号：US20100083407A1
公开(公告)日：2010-04-01
申请号：US12435281
申请日：2009-05-04
申请人： Kenneth A. Feldmann , Vyacheslav Brover , Vladimir Makarov , Timothy Swaller
发明人： Kenneth A. Feldmann , Vyacheslav Brover , Vladimir Makarov , Timothy Swaller
IPC分类号： C12N15/82 , C07H21/04 , C12N5/10 , C07K14/415 , A01H5/00 , C12Q1/68
CPC分类号： C07K14/415
摘要： Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants.

9. 发明申请

US20070031857A1 Compositions and methods for processing and amplification of DNA, including using multiple enzymes in a single reaction 审中-公开
标题翻译：用于处理和扩增DNA的组合物和方法，包括在单次反应中使用多种酶
公开(公告)号：US20070031857A1
公开(公告)日：2007-02-08
申请号：US11366222
申请日：2006-03-02
申请人： Vladimir Makarov , Emmanuel Kamberov , Brendan Tarrier
发明人： Vladimir Makarov , Emmanuel Kamberov , Brendan Tarrier
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6853 , C12N15/1068 , C12P19/34 , C12Q1/6855 , C12Q1/686 , C12Q1/6865 , C12Q2525/301 , C12Q2525/119 , C12Q2521/301 , C12Q2525/191 , C12Q2521/501
摘要： The present invention concerns preparation of DNA molecules, such as a library, using a stem-loop oligonucleotide. In particular embodiments, the invention employs a single reaction mixture and conditions. In particular, at least part of the inverted palindrome is removed during the preparation of the molecules to facilitate amplification of the molecules. Thus, in specific embodiments, the DNA molecules are suitable for amplification and are not hindered by the presence of the palindrome.
摘要翻译：本发明涉及使用茎环寡核苷酸制备DNA分子，例如文库。在具体实施方案中，本发明采用单一反应混合物和条件。特别地，在制备分子期间，至少部分反向回文被去除以促进分子的扩增。因此，在具体实施方案中，DNA分子适合于扩增，并且不受回文的存在的阻碍。

10. 发明申请

US20110288284A1 METHODS AND COMPOSITIONS FOR ISOLATING POLYNUCLEOTIDES 有权
标题翻译：用于分离多核苷酸的方法和组合物
公开(公告)号：US20110288284A1
公开(公告)日：2011-11-24
申请号：US13073781
申请日：2011-03-28
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： C07H21/00 , C12P19/34 , C12N9/12 , C07H1/00
CPC分类号： C12Q1/6806 , C12Q1/6813 , C12Q1/6816 , C12Q1/682 , C12Q1/6827 , C12Q1/683 , C12Q1/6844 , C12Q1/6846 , C12Q1/686 , C12Q1/6862 , C12Q1/6869 , C12Q1/6876 , C12Q2525/119 , C12Q2525/151 , C12Q2525/161 , C12Q2563/149 , C12Q2531/125 , C12Q2563/131 , C12Q2537/159
摘要： Methods of isolating target double-stranded polynucleotides with internal single-stranded regions are provided. Compositions and kits comprising double-stranded polynucleotides with internal single-stranded regions are also provided
摘要翻译：提供了用内部单链区域分离靶双链多核苷酸的方法。还提供了包含具有内部单链区域的双链多核苷酸的组合物和试剂盒

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