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1. 发明授权

US08889350B2 Methods and compositions for isolating polynucleotides 有权
标题翻译：用于分离多核苷酸的方法和组合物
公开(公告)号：US08889350B2
公开(公告)日：2014-11-18
申请号：US13073781
申请日：2011-03-28
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , C07H21/04 , C07H21/00
CPC分类号： C12Q1/6806 , C12Q1/6813 , C12Q1/6816 , C12Q1/682 , C12Q1/6827 , C12Q1/683 , C12Q1/6844 , C12Q1/6846 , C12Q1/686 , C12Q1/6862 , C12Q1/6869 , C12Q1/6876 , C12Q2525/119 , C12Q2525/151 , C12Q2525/161 , C12Q2563/149 , C12Q2531/125 , C12Q2563/131 , C12Q2537/159
摘要： Methods of isolating target double-stranded polynucleotides with internal single-stranded regions are provided. Compositions and kits comprising double-stranded polynucleotides with internal single-stranded regions are also provided.
摘要翻译：提供了用内部单链区域分离靶双链多核苷酸的方法。还提供了包含具有内部单链区域的双链多核苷酸的组合物和试剂盒。

2. 发明授权

US08555267B2 Performing register allocation of program variables based on priority spills and assignments 有权
标题翻译：基于优先级溢出和分配执行程序变量的寄存器分配
公开(公告)号：US08555267B2
公开(公告)日：2013-10-08
申请号：US12717042
申请日：2010-03-03
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： G06F9/45
摘要： A mechanism for performing register allocation based on priority spills and assignments is disclosed. A method of embodiments of the invention includes repetitively detecting fat points during a compilation process of a software program running on a virtual machine of a computer system, each fat point representing a program point having a high register pressure, the high register pressure occurs when a number of live program variables of the software program living at a given program point of the software program is greater than a number of available processor registers of the computer system. The method further includes choosing a fat point with a highest register pressure, selecting a live program variable having a lowest priority at the chosen fat point, and spilling the lowest priority live program variable to memory of the computer system.
摘要翻译：公开了一种基于优先溢出和分配进行寄存器分配的机制。本发明实施例的方法包括在计算机系统的虚拟机上运行的软件程序的编译过程中重复检测脂肪点，每个脂肪点表示具有高登记压力的程序点，当高生活在软件程序的给定程序点的软件程序的实际程序变量的数量大于计算机系统的可用处理器寄存器的数量。该方法还包括选择具有最高注册压力的脂肪点，选择在所选脂肪点具有最低优先级的实况节目变量，以及将最低优先级的实时节目变量溢出到计算机系统的存储器。

3. 发明授权

US08491964B1 Diamond nucleation using polyethene 失效
标题翻译：使用聚乙烯的金刚石成核
公开(公告)号：US08491964B1
公开(公告)日：2013-07-23
申请号：US13070214
申请日：2011-03-23
申请人： Gerardo Morell , Vladimir Makarov , Deepak Varshney , Brad Weiner
发明人： Gerardo Morell , Vladimir Makarov , Deepak Varshney , Brad Weiner
IPC分类号： C23C16/27
CPC分类号： C23C16/272
摘要： The invention presents a simple, non-destructive and non-abrasive method of diamond nucleation using polyethene. It particularly describes the nucleation of diamond on an electrically viable substrate surface using polyethene via chemical vapor deposition (CVD) technique in a gaseous environment.
摘要翻译：本发明提出了使用聚乙烯的金刚石成核的简单的，非破坏性和非研磨性的方法。它特别描述了在气体环境中通过化学气相沉积（CVD）技术使用聚乙烯在电存活的基底表面上金刚石的成核。

4. 发明申请

US20110129832A1 Polynucleotide Primers and Probes 审中-公开
标题翻译：多核苷酸引物和探针
公开(公告)号：US20110129832A1
公开(公告)日：2011-06-02
申请号：US12913742
申请日：2010-10-27
申请人： Vladimir Makarov , Sergey V. Chupreta
发明人： Vladimir Makarov , Sergey V. Chupreta
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6876 , C12Q1/6818 , C12Q1/6832 , C12Q2525/161 , C12Q2537/125 , C12Q2537/1373 , C12Q2537/163 , C12Q2525/121 , C12Q2525/301
摘要： The present invention provides a novel technology that involves improved primer design. These primer pairs have a wide range of applications and provide high sensitivity and specificity.
摘要翻译：本发明提供一种涉及改进底漆设计的新技术。这些引物对具有广泛的应用范围，提供高灵敏度和特异性。

5. 发明申请

US20100083407A1 NUCLEOTIDE SEQUENCES AND POLYPEPTIDES ENCODED THEREBY USEFUL FOR MODIFYING PLANT CHARACTERISTICS 审中-公开
公开(公告)号：US20100083407A1
公开(公告)日：2010-04-01
申请号：US12435281
申请日：2009-05-04
申请人： Kenneth A. Feldmann , Vyacheslav Brover , Vladimir Makarov , Timothy Swaller
发明人： Kenneth A. Feldmann , Vyacheslav Brover , Vladimir Makarov , Timothy Swaller
IPC分类号： C12N15/82 , C07H21/04 , C12N5/10 , C07K14/415 , A01H5/00 , C12Q1/68
CPC分类号： C07K14/415
摘要： Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants.

6. 发明申请

US20070031857A1 Compositions and methods for processing and amplification of DNA, including using multiple enzymes in a single reaction 审中-公开
标题翻译：用于处理和扩增DNA的组合物和方法，包括在单次反应中使用多种酶
公开(公告)号：US20070031857A1
公开(公告)日：2007-02-08
申请号：US11366222
申请日：2006-03-02
申请人： Vladimir Makarov , Emmanuel Kamberov , Brendan Tarrier
发明人： Vladimir Makarov , Emmanuel Kamberov , Brendan Tarrier
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6853 , C12N15/1068 , C12P19/34 , C12Q1/6855 , C12Q1/686 , C12Q1/6865 , C12Q2525/301 , C12Q2525/119 , C12Q2521/301 , C12Q2525/191 , C12Q2521/501
摘要： The present invention concerns preparation of DNA molecules, such as a library, using a stem-loop oligonucleotide. In particular embodiments, the invention employs a single reaction mixture and conditions. In particular, at least part of the inverted palindrome is removed during the preparation of the molecules to facilitate amplification of the molecules. Thus, in specific embodiments, the DNA molecules are suitable for amplification and are not hindered by the presence of the palindrome.
摘要翻译：本发明涉及使用茎环寡核苷酸制备DNA分子，例如文库。在具体实施方案中，本发明采用单一反应混合物和条件。特别地，在制备分子期间，至少部分反向回文被去除以促进分子的扩增。因此，在具体实施方案中，DNA分子适合于扩增，并且不受回文的存在的阻碍。

7. 发明授权

US08549508B2 Mechanism for performing instruction scheduling based on register pressure sensitivity 有权
标题翻译：基于寄存器压力灵敏度执行指令调度的机制
公开(公告)号：US08549508B2
公开(公告)日：2013-10-01
申请号：US12717028
申请日：2010-03-03
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： G06F9/45
CPC分类号： G06F9/30 , G06F9/455
摘要： A mechanism for performing instruction scheduling based on register pressure sensitivity is disclosed. A method of embodiments of the invention includes performing a preliminary register pressure minimization on program points during a compilation process of a software program running on a virtual machine of a computer system. The method further includes calculating a register pressure at each of the program points, detecting an instruction to be scheduled, and performing instruction scheduling of the instruction based on a current register pressure at a current scheduling point and potential register pressures at subsequent scheduling points.
摘要翻译：公开了一种基于寄存器压力灵敏度进行指令调度的机构。本发明的实施例的方法包括在计算机系统的虚拟机上运行的软件程序的编译过程中对程序点执行初步记录压力最小化。该方法还包括计算每个程序点处的寄存器压力，检测要调度的指令，并且基于当前调度点的当前寄存器压力和在后续调度点处的潜在寄存器压力来执行指令的指令调度。

8. 发明申请

US20110219364A1 Mechanism for Performing Register Allocation of Program Variables Based on Priority Spills and Assignments 有权
标题翻译：基于优先溢出和作业执行程序变量的寄存器分配机制
公开(公告)号：US20110219364A1
公开(公告)日：2011-09-08
申请号：US12717042
申请日：2010-03-03
申请人： Vladimir Makarov
发明人： Vladimir Makarov
IPC分类号： G06F9/45
摘要： A mechanism for performing register allocation based on priority spills and assignments is disclosed. A method of embodiments of the invention includes repetitively detecting fat points during a compilation process of a software program running on a virtual machine of a computer system, each fat point representing a program point having a high register pressure, the high register pressure occurs when a number of live program variables of the software program living at a given program point of the software program is greater than a number of available processor registers of the computer system. The method further includes choosing a fat point with a highest register pressure, selecting a live program variable having a lowest priority at the chosen fat point, and spilling the lowest priority live program variable to memory of the computer system.
摘要翻译：公开了一种基于优先溢出和分配进行寄存器分配的机制。本发明实施例的方法包括在计算机系统的虚拟机上运行的软件程序的编译过程中重复检测脂肪点，每个脂肪点表示具有高登记压力的程序点，当高生活在软件程序的给定程序点的软件程序的实际程序变量的数量大于计算机系统的可用处理器寄存器的数量。该方法还包括选择具有最高注册压力的脂肪点，选择在所选脂肪点具有最低优先级的实况节目变量，以及将最低优先级的实时节目变量溢出到计算机系统的存储器。

9. 发明授权

US07569389B2 Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics 有权
标题翻译：由此编码的核苷酸序列和多肽可用于修饰植物特征
公开(公告)号：US07569389B2
公开(公告)日：2009-08-04
申请号：US11241607
申请日：2005-09-30
申请人： Kenneth A. Feldmann , Vyacheslav Brover , Vladimir Makarov , Timothy Swaller
发明人： Kenneth A. Feldmann , Vyacheslav Brover , Vladimir Makarov , Timothy Swaller
IPC分类号： C12N15/82 , C12N5/04
CPC分类号： C07K14/415
摘要： Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants.
摘要翻译：描述了分离的多核苷酸和由此编码的多肽，以及这些产物用于制备转基因植物的用途。

10. 发明授权

US07515752B2 Sketch recognition and enhancement 有权
标题翻译：素描识别和增强
公开(公告)号：US07515752B2
公开(公告)日：2009-04-07
申请号：US10929021
申请日：2004-08-27
申请人： Christopher Jason Tremblay , Pascal Bécheiraz , Rick Charles Champagne , Valentin Ivanov , Daniel Jetté , Paul Legomski , Shawn Lipstein , Vladimir Makarov
发明人： Christopher Jason Tremblay , Pascal Bécheiraz , Rick Charles Champagne , Valentin Ivanov , Daniel Jetté , Paul Legomski , Shawn Lipstein , Vladimir Makarov
IPC分类号： G06K9/00
CPC分类号： G06K9/00402 , G06K9/00476
摘要： A drawing assistance system enhances a sketch drawn by a user in an electrical document on a computer system by collecting stroke data from one or more strokes of a sketch as a user draws the sketch. The stroke data includes time-based information and features of each stroke. The strokes are handled based on the time-based information, and analysed based on the strokes handled based on the time-based information. The sketch is enhanced based on results of the analysis.
摘要翻译：绘图辅助系统通过在用户绘制草图时通过从草图的一个或多个笔画收集笔触数据来增强用户在计算机系统上的电子文档中绘制的草图。笔画数据包括基于时间的信息和每个笔画的特征。基于时间信息处理笔画，并且基于基于时间信息处理的笔划进行分析。基于分析结果增强了草图。

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