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1. 发明授权

US6156053A Dual catheter assembly 失效
标题翻译：双导管组装
公开(公告)号：US6156053A
公开(公告)日：2000-12-05
申请号：US71018
申请日：1998-05-01
申请人： Deepak R. Gandhi , Cecily M. Hillsman , Anant V. Hegde , Harm TenHoff
发明人： Deepak R. Gandhi , Cecily M. Hillsman , Anant V. Hegde , Harm TenHoff
IPC分类号： A61F2/82 , A61M25/09 , A61M29/00
CPC分类号： A61M25/1011 , A61F2/958 , A61F2002/826
摘要： The present invention relates to a combination device comprising two catheters, or a dual catheter assembly, for use in vascular procedures wherein the shaft of the first catheter functions as a guidewire for the second catheter. The dual catheter assembly comprises a first balloon catheter and a second balloon catheter wherein the second balloon catheter is slidably disposed on the shaft of the first balloon. In preferred embodiments, the first catheter is a low profile balloon on a wire catheter and the second catheter is a full size balloon catheter having a plurality of balloons mounted thereon. Optionally, a stent is carried by at least one of the balloons on the second catheter. In more preferred embodiments, the second catheter includes a manifold that may be used to inflate and deflate any combination of the plurality of balloons via a single port. The dual catheter assembly of the present invention is especially useful in vascular procedures such as angioplasty, progressive/multiple angioplasty, and stent delivery.
摘要翻译：本发明涉及一种组合装置，其包括用于血管程序的两个导管或双重导管组件，其中第一导管的轴用作第二导管的导丝。双重导管组件包括第一气囊导管和第二气囊导管，其中第二球囊导管可滑动地设置在第一气囊的轴上。在优选实施例中，第一导管是导线导管上的低轮廓气囊，并且第二导管是其上安装有多个气囊的全尺寸球囊导管。任选地，支架由第二导管上的气囊中的至少一个承载。在更优选的实施例中，第二导管包括可用于经由单个端口对多个气囊的任何组合进行充气和放气的歧管。本发明的双导管组件在诸如血管成形术，进行性/多重血管成形术和支架递送的血管手术中特别有用。

2. 发明授权

US5725535A Multiple balloon stent delivery catheter and method 失效
标题翻译：多球囊支架输送导管及方法
公开(公告)号：US5725535A
公开(公告)日：1998-03-10
申请号：US717299
申请日：1996-09-20
申请人： Anant V. Hegde , Deepak R. Gandhi , Thomas Bourne , James R. Kermode
发明人： Anant V. Hegde , Deepak R. Gandhi , Thomas Bourne , James R. Kermode
IPC分类号： A61F2/82 , A61F2/06 , A61F2/84 , A61M25/00 , A61M25/10 , A61F11/00
CPC分类号： A61F2/958 , A61M25/1011 , A61M2025/1013
摘要： A multiple balloon catheter for use in a vessel of a patient and for use with an inflation/deflation device. A flexible elongate tubular member with proximal and distal extremities has a distal balloon mounted on the distal extremity of the flexible elongate tubular member. Coaxial inner and outer balloons are mounted on the distal extremity of the flexible elongate member proximal of the distal balloon. The flexible elongate tubular member has balloon inflation lumens therein in communication with the interiors of the distal balloon and the inner and outer coaxial balloons. A manifold is secured to the proximal extremity of the flexible elongate tubular member in communication with the inflation lumens and is adjusted to be coupled to the inflation/deflation device. Valves are carried by the inflation/deflation manifold for inflating the distal balloon in the inner and outer coaxial balloons one at a time or in unison without removal of the inflation/deflation device from the manifold.
摘要翻译：一种用于患者血管并用于充气/放气装置的多气囊导管。具有近端和远端的柔性细长管状构件具有安装在柔性细长管状构件的远端上的远端球囊。同轴的内外球囊安装在远端球囊近端的柔性细长构件的远端上。柔性细长管状构件具有与远侧气囊和内外同轴气囊的内部连通的球囊充气腔。歧管固定到与膨胀腔连通的柔性细长管状构件的近端，并且被调节以联接到充气/放气装置。阀通过充气/放气歧管携带，用于一次一个地或一致地充气内外同轴气囊中的远端球囊，而不从歧管中移除充气/放气装置。

3. 发明授权

US5766203A Sheath with expandable distal extremity and balloon catheters and stents for use therewith and method 失效
标题翻译：具有可扩展的远端末端和气囊导管和与其一起使用的支架的护套和方法
公开(公告)号：US5766203A
公开(公告)日：1998-06-16
申请号：US728769
申请日：1996-10-10
申请人： Mir A. Imran , Deepak R. Gandhi , Anant V. Hegde , Gholam-Reza Zadno-Azizi
发明人： Mir A. Imran , Deepak R. Gandhi , Anant V. Hegde , Gholam-Reza Zadno-Azizi
IPC分类号： A61F2/06 , A61F2/84 , A61M25/00 , A61M25/06 , A61M29/00
CPC分类号： A61F2/958 , A61M2025/0063 , A61M2025/1086 , A61M25/005 , A61M25/0053 , A61M25/0668
摘要： A sheath for advancement into a vessel of a patient having a stenosis therein which at least partially occludes the flow of blood in the vessel. A flexible elongate tubular member has proximal and distal extremities with a lumen extending from the proximal extremity to the distal extremity. A portion of the distal extremity of the flexible elongate tubular member is radially expandable. The expandable portion carries stiffening elements that impart pushability and column strength to the expandable portion.
摘要翻译：用于进入其中具有狭窄的患者的血管的护套，其至少部分地封闭血管中的血液流。柔性细长管状构件具有近端和远端，其末端具有从近端延伸到远端的内腔。柔性细长管状构件的远端的一部分是可径向扩张的。可膨胀部分承载加强元件，其赋予可膨胀部分的推压性和柱强度。

4. 发明授权

US5788708A Multiple balloon stent delivery catheter and method 失效
公开(公告)号：US5788708A
公开(公告)日：1998-08-04
申请号：US949726
申请日：1997-10-14
申请人： Anant V. Hegde , Deepak R. Gandhi , Thomas Bourne , James R. Kermode
发明人： Anant V. Hegde , Deepak R. Gandhi , Thomas Bourne , James R. Kermode
IPC分类号： A61F2/82 , A61F2/06 , A61F2/84 , A61M25/00 , A61M25/10 , A61F11/00
CPC分类号： A61F2/958 , A61M25/1011 , A61M2025/1013
摘要： A multiple balloon catheter for use in a vessel of a patient and for use with an inflation/deflation device. A flexible elongate tubular member with proximal and distal extremities has a distal balloon mounted on the distal extremity of the flexible elongate tubular member. Coaxial inner and outer balloons are mounted on the distal extremity of the flexible elongate member proximal of the distal balloon. The flexible elongate tubular member has balloon inflation lumens therein in communication with the interiors of the distal balloon and the inner and outer coaxial balloons. A manifold is secured to the proximal extremity of the flexible elongate tubular member in communication with the inflation lumens and is adjusted to be coupled to the inflation/deflation device. Valves are carried by the inflation/deflation manifold for inflating the distal balloon in the inner and outer coaxial balloons one at a time or in unison without removal of the inflation/deflation device from the manifold.

5. 发明授权

US5662608A Low profile balloon catheter and method 失效
标题翻译：低调气囊导管及方法
公开(公告)号：US5662608A
公开(公告)日：1997-09-02
申请号：US507655
申请日：1995-07-26
申请人： Mir A. Imran , Deepak R. Gandhi , Anant V. Hegde
发明人： Mir A. Imran , Deepak R. Gandhi , Anant V. Hegde
IPC分类号： A61M25/00 , A61F2/958 , A61M25/01 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61M25/1002 , A61M25/1011 , A61M2025/1013
摘要： A low profile catheter comprising a flexible elongate tubular member having proximal and distal extremities and having a guide wire lumen and at least one balloon inflation lumen extending from the proximal extremity to the distal extremity, said at least one balloon inflation lumen being offset eccentrically with respect to said guide wire lumen, the distal extremity of said flexible elongate tubular member having at least one inflatable balloon formed thereon and having an interior in communication with said at least one balloon inflation lumen, said guide wire lumen extending through said at least one inflatable balloon and being offset eccentrically with respect to said at least one inflatable balloon.
摘要翻译：一种低剖面导管，其包括具有近端和远端的柔性细长管状构件，并且具有导丝腔和至少一个从近端至远端延伸的球囊充气腔，所述至少一个球囊充气腔相对于所述柔性细长管状构件的远端末端具有形成在其上的至少一个可膨胀气囊，并且具有与所述至少一个球囊膨胀腔连通的内部，所述导丝腔延伸穿过所述至少一个可充气球囊并且相对于所述至少一个可充气气球偏心偏移。

6. 发明授权

US08578937B2 Smart mandibular repositioning system 有权
标题翻译：智能下颌骨重新定位系统
公开(公告)号：US08578937B2
公开(公告)日：2013-11-12
申请号：US12235531
申请日：2008-09-22
申请人： Nikhil D. Bhat , Anant V. Hegde , Charisse M. Yung , George Y. Choi
发明人： Nikhil D. Bhat , Anant V. Hegde , Charisse M. Yung , George Y. Choi
IPC分类号： A61F5/56 , A61F5/37
CPC分类号： A61B5/4818 , A61B5/0031 , A61B5/076 , A61B5/1076 , A61B5/682 , A61F2/02 , A61F5/566
摘要： Systems and methods for detecting an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor attached to a region in an airway passage in an oral cavity. The electrical output may be wirelessly transmitted as a signal for indication of an obstructive sleep apnea event. The signal may be further processed by a smart mandibular repositioning system for treatment of the obstructive sleep apnea event.
摘要翻译：本文公开了用于检测阻塞性睡眠呼吸暂停事件的系统和方法。系统和方法可以使用附着在口腔中的气道通道中的区域的电输出产生离子聚合物金属复合传感器。电输出可以作为用于指示阻塞性睡眠呼吸暂停事件的信号被无线发送。该信号可以由用于治疗阻塞性睡眠呼吸暂停事件的智能下颌骨重新定位系统进一步处理。

7. 发明授权

US08256425B2 Methods and devices for removal of a tongue stabilization device 有权
标题翻译：用于去除舌头稳定装置的方法和装置
公开(公告)号：US08256425B2
公开(公告)日：2012-09-04
申请号：US12211082
申请日：2008-09-15
申请人： Christopher Bagley , Casidy Domingo , Anant V. Hegde
发明人： Christopher Bagley , Casidy Domingo , Anant V. Hegde
IPC分类号： A61F5/37 , A61F13/00 , A61F2/06 , A61F2/02 , A61D1/12
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , A61F2210/0038
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods and devices for removing, the device are also disclosed. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了用于移除的方法和装置，该装置也被公开。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

8. 发明授权

US07909037B2 Tethered airway implants and methods of using the same 有权
标题翻译：束缚气道植入物及其使用方法
公开(公告)号：US07909037B2
公开(公告)日：2011-03-22
申请号：US11737107
申请日：2007-04-18
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
IPC分类号： A61F5/56 , A61F13/00 , A61F5/04 , A61F2/30 , A61F2/00 , A61B19/00 , A61B17/56 , A61B17/58 , A61B17/70
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , G02B26/0841 , H02N1/008 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device includes a deformable element to control the opening of an air passageway and a tether. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Also disclosed is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; and an anchoring portion for connecting the implant with the base of the tongue connected with the distal end of the flexible portion. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。气道植入装置包括可变形元件以控制空气通道和系绳的开口。优选地，可变形元件是电活性聚合物元件。电活性聚合物元件的通电为空气通道的壁提供支撑，当壁崩溃时，从而完全或部分地打开空气通道。还公开了一种用于稳定舌头的植入物，植入物具有用于固定植入物的第一端与下颌骨的锚固部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 以及用于将植入物与与柔性部分的远端连接的舌头的基部连接的锚固部分。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

9. 发明申请

US20100004659A1 Cavitation Depth, Perforation Confirmation and Implant Delivery Tool 有权
标题翻译：气蚀深度，穿孔确认和植入物交付工具
公开(公告)号：US20100004659A1
公开(公告)日：2010-01-07
申请号：US12168825
申请日：2008-07-07
申请人： Anant V. Hegde , Adrian McVicker , Jerry Sung Woo Choe , James B. Ross
发明人： Anant V. Hegde , Adrian McVicker , Jerry Sung Woo Choe , James B. Ross
IPC分类号： A61B17/58 , A61F5/56 , A61F13/20
CPC分类号： A61F5/566
摘要： Methods and tools that insert implants for the treatment of snoring and sleep apnea in a cavity created in the patient's tissue are disclosed. Some tools and methods can additionally verify that the cavity has proper cavitation depth and does not have unwanted perforations. The tools include: a sheath having a substantially flat portion for housing an implant, the sheath having a distal end and a proximal end, the sheath having a hollow collar on the proximal end, an insertion depth mark near the distal end, and a slit on the distal end, the slit being in fluid communication with the hollow collar; a substantially rigid pusher configured to be disposed within and in slidable engagement with the sheath, the pusher having a distal end and a proximal end, the pusher having a rigid body having an outside diameter for slidably engaging with the hollow collar of the sheath, a tip on the distal end for engaging a proximal end of an implant, and a lumen extending from said proximal side to said distal side of said rigid body, the lumen configured for fluid communication with a syringe at the proximal end and in fluid communication with the sheath at the distal end.
摘要翻译：公开了在患者组织中产生的腔中插入用于治疗打鼾和睡眠呼吸暂停的植入物的方法和工具。一些工具和方法可以另外验证空腔具有适当的空化深度并且不具有不需要的穿孔。所述工具包括：护套，其具有用于容纳植入物的基本上平坦的部分，所述护套具有远端和近端，护套在近端具有中空的环，在远端附近具有插入深度标记，在所述远端处，所述狭缝与所述中空轴环流体连通; 一个基本上刚性的推动器，其构造成设置在护套内并与护套滑动接合，该推动器具有远端和近端，该推动器具有刚体，该刚体具有用于与护套的空心环滑动接合的外径，在远端上的尖端用于接合植入物的近端，以及从所述刚体的所述近侧延伸到所述远端侧的内腔，所述内腔构造成用于在近端处与注射器流体连通并且与所述近端流体连通护套在远端。

10. 发明申请

US20090069866A1 IMPLANT TESTER 审中-公开
标题翻译：植入物检测仪
公开(公告)号：US20090069866A1
公开(公告)日：2009-03-12
申请号：US12205625
申请日：2008-09-05
申请人： John Michael Farbarik , John C. Potosky , Anant V. Hegde , Casidy Domingo , Charisse M. Yung , Nikhil D. Bhat , George Yoseung Choi
发明人： John Michael Farbarik , John C. Potosky , Anant V. Hegde , Casidy Domingo , Charisse M. Yung , Nikhil D. Bhat , George Yoseung Choi
IPC分类号： A61N1/08
CPC分类号： A61B5/06 , A61B5/0031 , A61B5/076 , A61B5/682 , A61B5/6882 , A61F2/02 , A61F5/56 , G01V15/00
摘要： An implant testing device and a method of detecting an airway implant are disclosed. The testing device detects the presence of the implant within a patient's body and can be used to determine its location. The testing device also provides an indication of proper function of the implant electronics. A detector circuit of the testing device generates an output signal representative of proximity of the airway implant. A processing circuit receives the output signal and determines proximity of the implant based on one or more detection thresholds. The processing circuit also provides a visual and/or audible alert. In some embodiments, the processing circuit varies the flash rate of one or more light emitting diodes and/or the pitch of an alert tone based on proximity of the implant. Various embodiments of the testing device are adapted for handheld use and can include a handle, elongated portion, and detector element.
摘要翻译：公开了一种植入物测试装置和一种检测气道植入物的方法。测试装置检测植入物在患者体内的存在并且可用于确定其位置。测试装置还提供植入电子器件的正常功能的指示。测试装置的检测器电路产生表示气道植入物接近的输出信号。处理电路接收输出信号并且基于一个或多个检测阈值确定植入物的接近度。处理电路还提供视觉和/或听觉警报。在一些实施例中，处理电路基于植入物的接近度改变一个或多个发光二极管的闪光速率和/或警报音调的音调。测试装置的各种实施例适用于手持使用，并且可以包括手柄，细长部分和检测器元件。

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