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1. 发明授权

US06332881B1 Surgical ablation tool 失效
标题翻译：手术消融工具
公开(公告)号：US06332881B1
公开(公告)日：2001-12-25
申请号：US09387889
申请日：1999-09-01
申请人： David J. Carner , Reynaldo P. Hilario , Mahmoud K. Seraj
发明人： David J. Carner , Reynaldo P. Hilario , Mahmoud K. Seraj
IPC分类号： A61I1818
CPC分类号： A61B18/1402 , A61B18/1492
摘要： This is a tool used during open heart or open chest surgery for creating lesions or lines of ablation in tissue to treat atrial fibrillation. It is a relatively short device having a rigid or semi-rigid shaft connected on one end to a handle and on the other end to a more flexible distal tip having one or more electrodes. The distal end of the shaft is angled so to define a first plane of deflection. A deflection mechanism consisting of a pull wire and flat spring housed in a lumen of the tool is manipulable via the handle for deflecting the distal tip in a plane different than the first plane of deflection, allowing direct contact with the curved surface of the tissue, either epicardial or endocardial, to be ablated. The tool may contain fiber optic or other data lines for transmitting data relevant to the patient, and it may be irrigated to cool the tool and the electrodes or to deliver therapeutic fluids to tissue. The tool may also contain temperature sensing device such as a thermocouple or thermistor, which can optionally be configured in a feedback and control system with the irrigation to selectively monitor and control the temperature of the tool or surrounding tissue.
摘要翻译：这是在开胸或胸部手术期间用于创建组织中的损伤或消融线以治疗心房颤动的工具。它是相对短的装置，其具有刚性或半刚性轴，其一端连接到手柄，另一端连接到具有一个或多个电极的更柔性的远侧末端。轴的远端成角度以限定第一偏转平面。由拉线和平板弹簧组成的偏转机构可容纳在工具的内腔中，可通过手柄操纵，用于在远离第一平面的偏转平面偏转远端，允许与组织的曲面直接接触，心外膜或心内膜，要消融。该工具可以包含用于传送与患者相关的数据的光纤或其他数据线，并且可以灌溉以冷却工具和电极或将治疗流体输送到组织。该工具还可以包含诸如热电偶或热敏电阻的温度感测装置，其可以可选地配置在具有灌溉的反馈和控制系统中，以选择性地监测和控制工具或周围组织的温度。

2. 发明授权

US06746446B1 Electrophysiological device for the isthmus 失效
标题翻译：峡谷电生理装置
公开(公告)号：US06746446B1
公开(公告)日：2004-06-08
申请号：US09633054
申请日：2000-08-04
申请人： E. Richard Hill, III , Sung Chun , Reynaldo P. Hilario , Tim Ngeo Huynh , Mahmoud R. Seraj , Robert Obara
发明人： E. Richard Hill, III , Sung Chun , Reynaldo P. Hilario , Tim Ngeo Huynh , Mahmoud R. Seraj , Robert Obara
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2017/00867 , A61B2018/00029 , A61B2018/00351 , A61B2018/00797 , A61B2018/00821 , A61B2018/00839 , A61B2018/1467 , C08L2201/12
摘要： An intravascular electrophysiology (EP) device for the mapping and/or formation of lesions along the isthmus region of a heart that has particular utility in the treatment of atrial flutter. The EP device of the invention has an elongated shaft with a proximal section, a compound-curved or modified pigtail-shaped distal section, and a plurality of at least partially exposed electrodes disposed on an outer surface of the distal section. The electrodes are spaced along a length of the distal section and may be interspersed with at least one temperature sensor located between electrodes. The shape of the distal end of the device enables manipulation of the device by inserting its distal end in the tricuspid valve and retracting the device to bias the section having electrodes along the isthmus to achieve acceptable contact with the region so high frequency (e.g., RF) electrical energy delivered to the electrodes on the distal section of the EP device will form a lesion. Sections of the isthmus where treatment is desired but not reached by the section of the device biased against tissue by retraction may be ablated by repeating the steps of hooking the tricuspid valve at a different end location of the device and retracting to bias the electrodes against different tissue, simply advancing the section with electrodes to the desired site or retracting the device so a tip connected to an RF source will drop into a desired site where ablation may occur.
摘要翻译：用于沿着心脏的峡部区域映射和/或形成病变的血管内电生理学（EP）装置，其特别用于治疗心房扑动。本发明的EP装置具有细长轴，其具有近端部分，复合弯曲或修改的尾纤形远端部分，以及设置在远侧部分的外表面上的多个至少部分暴露的电极。电极沿着远端部分的长度间隔开，并且可以散布在位于电极之间的至少一个温度传感器。该装置的远端的形状使得能够通过将其远端插入三尖瓣并且缩回装置来偏转具有沿着峡部的电极的部分来实现装置的操作，以实现与该区域的可接受的接触，从而高频（例如，RF ）传送到EP装置的远端部分上的电极的电能将形成病变。可以通过重复将三尖瓣钩挂在装置的不同端部位置的步骤来消除通过缩回偏压组织的装置的部分而不能达到处理的部位，并且缩回以将电极偏压到不同的位置组织，简单地将具有电极的部分推进到所需位置或缩回装置，使得连接到RF源的尖端将落入可能发生消融的期望位置。

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