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    • 2. 发明申请
    • Method for printing unidirectional and see-through graphics
    • 打印单向和直通图形的方法
    • US20050123707A1
    • 2005-06-09
    • US10986757
    • 2004-11-12
    • Ronald VeckPaul St-PierreJames RamsdenTrevor SimmondsGordon ReynenDavid Evans
    • Ronald VeckPaul St-PierreJames RamsdenTrevor SimmondsGordon ReynenDavid Evans
    • B05D1/32B32B1/00B32B3/00B32B3/30B32B33/00B41M3/14B42D15/00B44C1/00B44F1/06
    • B44C1/16B41M3/148B44F1/06Y10T428/14Y10T428/2457Y10T428/24612Y10T428/24736
    • A convenient, time-efficient, easy-to-use method for creating a substrate covering comprising graphic images, such that the substrate covering can be substantially opaque to an observer looking from one side of the substrate (allowing him to see an image), yet the observer is able to see through the substrate covering from the other side of the substrate, or such that an observer would be able to see the images as well as objects beyond the substrate, comprising the steps of (1) creating an outline for the substrate covering; (2) creating at least one artwork; (3) launching a window wizard, which allows a user to select the position of the covering with respect to the substrate; at least one artwork; and at least one primer in accordance with the desired visual effects; (4) selecting the position of the covering with respect to the substrate; at least one artwork; and at least one primer in accordance with the desired visual effects; and (5) sending the window wizard output for printing onto a substantially clear laminate that could be applied to the substrate, wherein stacked layers of the selected artwork and selected primers are printed with perforations onto said laminate, wherein the perforations of the stacked layers are aligned.
    • 用于创建包括图形图像的基板覆盖物的方便,时间高效的易于使用的方法,使得基板覆盖物可以从观察者的基底的一侧观察到基本上不透明(允许其看到图像), 但是观察者能够从衬底的另一侧穿过衬底覆盖物,或者使得观察者能够看到图像以及超出衬底的物体,包括以下步骤:(1)创建用于 基材覆盖层; (2)创建至少一幅作品; (3)启动窗口向导,其允许用户相对于基板选择覆盖物的位置; 至少有一件作品; 和至少一种根据所需视觉效果的底漆; (4)相对于基板选择覆盖物的位置; 至少有一件作品; 和至少一种根据所需视觉效果的底漆; 并且(5)将用于印刷的窗口向导输出发送到可施加到基底上的基本上透明的层压体上,其中所选择的图案和所选底漆的堆叠层被穿孔印刷到所述层压板上,其中堆叠层的穿孔为 对齐
    • 3. 发明授权
    • Method for printing unidirectional and see-through graphics
    • 打印单向和直通图形的方法
    • US07384669B2
    • 2008-06-10
    • US10986757
    • 2004-11-12
    • Ronald VeckPaul St-PierreJames RamsdenTrevor SimmondsGordon ReynenDavid Evans
    • Ronald VeckPaul St-PierreJames RamsdenTrevor SimmondsGordon ReynenDavid Evans
    • B05D5/06
    • B44C1/16B41M3/148B44F1/06Y10T428/14Y10T428/2457Y10T428/24612Y10T428/24736
    • A convenient, time-efficient, easy-to-use method for creating a substrate covering comprising graphic images, such that the substrate covering can be substantially opaque to an observer looking from one side of the substrate (allowing him to see an image), yet the observer is able to see through the substrate covering from the other side of the substrate, or such that an observer would be able to see the images as well as objects beyond the substrate, comprising the steps of (1) creating an outline for the substrate covering; (2) creating at least one artwork; (3) launching a window wizard, which allows a user to select the position of the covering with respect to the substrate; at least one artwork; and at least one primer in accordance with the desired visual effects; (4) selecting the position of the covering with respect to the substrate; at least one artwork; and at least one primer in accordance with the desired visual effects; and (5) sending the window wizard output for printing onto a substantially clear laminate that could be applied to the substrate, wherein stacked layers of the selected artwork and selected primers are printed with perforations onto said laminate, wherein the perforations of the stacked layers are aligned.
    • 用于创建包括图形图像的基板覆盖物的方便,时间高效的易于使用的方法,使得基板覆盖物可以从观察者的基底的一侧观察到基本上不透明(允许其看到图像), 但是观察者能够从衬底的另一侧穿过衬底覆盖物,或者使得观察者能够看到图像以及超出衬底的物体,包括以下步骤:(1)创建用于 基材覆盖层; (2)创建至少一幅作品; (3)启动窗口向导,其允许用户相对于基板选择覆盖物的位置; 至少有一件作品; 和至少一种根据所需视觉效果的底漆; (4)相对于基板选择覆盖物的位置; 至少有一件作品; 和至少一种根据所需视觉效果的底漆; 并且(5)将用于印刷的窗口向导输出发送到可施加到基底上的基本上透明的层压体上,其中所选择的图案和所选底漆的堆叠层被穿孔印刷到所述层压板上,其中堆叠层的穿孔为 对齐
    • 6. 发明申请
    • System For Purifying, Producing And Storing Biomolecules
    • 净化,生产和储存生物分子系统
    • US20140037961A1
    • 2014-02-06
    • US14111305
    • 2012-04-12
    • David Evans
    • David Evans
    • C07C319/28C07K17/02C07C323/58C07K1/22C07C59/347
    • C07C319/28A61K47/6817A61K47/6855B01J20/287B01J20/3212B01J20/3219B01J20/3248B01J20/3251B01J20/3274C07C59/347C07C323/58C07K1/22C07K17/02Y10T428/2982
    • The invention relates to a lock-release method to be applied to biomolecules, such as antibodies, to improve the purification, production, stability and storage of biomolecules. A biomolecule is covalently bound to a polymer support comprising a diketone group so that the biomolecule can be purified, produced and/or stored before being released from the support. The diketone group of the polymer support is a 1,3-ketoester, 1,3-ketothioester or 1,3-ketoamide is a group of Formula (1): R1 is an optionally substituted hydrocarbyl, perhalogenated hydrocarbyl, or a heterocyclyl group; Y is hydrogen, an optionally substituted hydrocarbyl, or a heterocyclyl group; X is —O, —NR2 or —S, wherein the free valence of —O, —NR2 or —S is bonded to the support optionally via a linker; and R2 is hydrogen, an optionally substituted hydrocarbyl, or a heterocyclyl group. The invention also relates to a polymer support comprising the diketone group.
    • 本发明涉及一种应用于生物分子如抗体的锁定释放方法,以改善生物分子的纯化,生产,稳定性和储存。 生物分子与包含二酮基团的聚合物载体共价结合,使得生物分子可以在从载体释放之前被纯化,产生和/或储存。 聚合物载体的二酮基团是1,3-酮酯,1,3-酮硫代酯或1,3-酮酰胺是式(1)的基团:R 1是任选取代的烃基,全卤代烃基或杂环基; Y是氢,任选取代的烃基或杂环基; X是-O,-NR 2或-S,其中-O,-NR 2或-S的游离基任选地经由连接基与支持基结合; 和R 2是氢,任选取代的烃基或杂环基。 本发明还涉及包含二酮基团的聚合物载体。