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1. 发明申请

US20050130214A1 Molecular binding event detection using separation channels 审中-公开
公开(公告)号：US20050130214A1
公开(公告)日：2005-06-16
申请号：US11015827
申请日：2004-12-17
申请人： David Biegelsen , Robert Street
发明人： David Biegelsen , Robert Street
IPC分类号： G01N27/447 , G01N33/543 , G06F19/00 , C12Q1/68 , G01N33/53 , G01N33/48 , G01N33/50 , G01N33/558
CPC分类号： G01N27/44726 , G01N33/54333 , G16B20/00
摘要： Detecting binding events between first and second molecules (e.g., ligands and proteins) includes mixing at the first end of a test channel, then separating the bound/unbound molecules (e.g., using electrophoresis) by causing the molecules to move down the channel such that groups of bound/unbound molecules move along the channel at different rates. The groups are then detected, measured and compared against established reference data to determine whether a binding event has occurred. A reference channel is utilized to provide reference data and to identify unbound molecule groups. Radiant energy and a bolometer are utilized to measure the molecule groups

2. 发明申请

US20050130319A1 Molecular binding event detection using separation channels 审中-公开
标题翻译：使用分离通道的分子结合事件检测
公开(公告)号：US20050130319A1
公开(公告)日：2005-06-16
申请号：US10737692
申请日：2003-12-15
申请人： David Biegelsen , Robert Street
发明人： David Biegelsen , Robert Street
IPC分类号： G01N27/447 , G01N33/543 , G06F19/00 , G01N33/558
CPC分类号： G01N27/44726 , G01N33/54333 , G16B20/00
摘要： Detecting binding events between first and second molecules (e.g., ligands and proteins) includes mixing at the first end of a test channel, then separating the bound/unbound molecules (e.g., using electrophoresis) by causing the molecules to move down the channel such that groups of bound/unbound molecules move along the channel at different rates. The groups are then detected, measured and compared against established reference data to determine whether a binding event has occurred. A reference channel is utilized to provide reference data and to identify unbound molecule groups. Radiant energy and a bolometer are utilized to measure the molecule groups
摘要翻译：检测第一和第二分子（例如配体和蛋白质）之间的结合事件包括在测试通道的第一端进行混合，然后通过使分子向下移动通道来分离结合/未结合的分子（例如，使用电泳），使得束缚/未结合的分子团以不同的速率沿着通道移动。然后检测，测量和比较组与已建立的参考数据，以确定是否发生了结合事件。参考通道用于提供参考数据并识别未结合的分子组。利用辐射能和辐射热计测量分子群

3. 发明授权

US08550603B2 Systems and methods for transporting particles 有权
标题翻译：运输颗粒的系统和方法
公开(公告)号：US08550603B2
公开(公告)日：2013-10-08
申请号：US12712855
申请日：2010-02-25
申请人： Armin R. Volkel , David Biegelsen , Philip D. Floyd , Greg Anderson , Fred Endicott , Eric Peeters , Jaan Noolandi , Karen A. Moffat , Peter M. Kazmaier , Maria McDougall , Daniel G. Bobrow
发明人： Armin R. Volkel , David Biegelsen , Philip D. Floyd , Greg Anderson , Fred Endicott , Eric Peeters , Jaan Noolandi , Karen A. Moffat , Peter M. Kazmaier , Maria McDougall , Daniel G. Bobrow
IPC分类号： B41J2/175
CPC分类号： B03C5/028
摘要： Various particle transport systems and components for use in such systems are described. The systems utilize one or more traveling wave grids to selectively transport, distribute, separate, or mix different populations of particles. Numerous systems configured for use in two dimensional and three dimensional particle transport are described.
摘要翻译：描述了用于这种系统的各种粒子输送系统和部件。该系统利用一个或多个行波网来选择性地输送，分配，分离或混合不同粒子群。描述了配置用于二维和三维粒子传输的许多系统。

4. 发明申请

US20130033688A1 System for Direct Application of Dampening Fluid for a Variable Data Lithographic Apparatus 有权
标题翻译：用于可变数据平版印刷设备的缓冲液的直接应用系统
公开(公告)号：US20130033688A1
公开(公告)日：2013-02-07
申请号：US13204548
申请日：2011-08-05
申请人： Timothy Stowe , David Biegelsen , Lars-Erik Swartz , Jurgen Daniel
发明人： Timothy Stowe , David Biegelsen , Lars-Erik Swartz , Jurgen Daniel
IPC分类号： G03B27/52
CPC分类号： B41F7/30 , B41C1/1033 , B41F7/32 , B41F7/34 , B41P2227/70
摘要： A system and corresponding methods are disclosed for applying a dampening fluid to a reimageable surface of an imaging member in a variable data lithography system, without a form roller. In one embodiment, the system includes subsystems for converting a dampening fluid from a liquid phase to a dispersed fluid phase, and for directing flow of a dispersed fluid comprising the dampening fluid in dispersed fluid phase to the reimageable surface. The dampening fluid reverts to the liquid phase directly on the reimageable surface. In another embodiment a continuous ribbon of dampening fluid may be applied directly to the reimageable surface. This embodiment includes a body structure having a port for delivering dampening fluid in a continuous fluid ribbon directly to the reimageable surface, and a mechanism, associated with the body structure, for stripping an entrained air layer over the reimageable surface when the reimageable surface is in motion.
摘要翻译：公开了一种用于将润版流体施加到可变数据光刻系统中的成像构件的可再成像表面的系统和相应方法，而没有成形辊。在一个实施例中，该系统包括用于将润湿流体从液相转化为分散流体相的子系统，并且用于将包含分散流体相的润版液的分散流体的流动引导到可再成像的表面。阻尼流体直接在可再成像的表面上回流到液相。在另一个实施例中，连续的润版液体带可以直接施加到可再成像的表面。该实施例包括具有端口的主体结构，该端口用于将连续流体带中的阻尼流体直接传送到可再成像的表面，以及与主体结构相关联的机构，用于当可再成像的表面处于可再成像的表面时，将夹带的空气层剥离在可再成像的表面上运动。

5. 发明申请

US20130033686A1 Direct Application of Dampening Fluid for a Variable Data Lithographic Apparatus 审中-公开
标题翻译：缓冲液直接应用于可变数据平版印刷设备
公开(公告)号：US20130033686A1
公开(公告)日：2013-02-07
申请号：US13204515
申请日：2011-08-05
申请人： Timothy Stowe , Ashish Pattekar , Eric Peeters , David Biegelsen , Lars-Erik Schwartz , Jurgen Daniel
发明人： Timothy Stowe , Ashish Pattekar , Eric Peeters , David Biegelsen , Lars-Erik Schwartz , Jurgen Daniel
IPC分类号： G03B27/52
CPC分类号： B41F7/30 , B41C1/1033 , B41F7/32 , B41F7/34 , B41P2227/70
摘要： A system and corresponding methods are disclosed for applying a dampening fluid to a reimageable surface of an imaging member in a variable data lithography system, without a form roller. In one embodiment, the system includes subsystems for converting a dampening fluid from a liquid phase to a dispersed fluid phase, and for directing flow of a dispersed fluid comprising the dampening fluid in dispersed fluid phase to the reimageable surface. The dampening fluid reverts to the liquid phase directly on the reimageable surface. In another embodiment a continuous ribbon of dampening fluid may be applied directly to the reimageable surface. This embodiment includes a body structure having a port for delivering dampening fluid in a continuous fluid ribbon directly to the reimageable surface, and a mechanism, associated with the body structure, for stripping an entrained air layer over the reimageable surface when the reimageable surface is in motion.
摘要翻译：公开了一种用于将润版流体施加到可变数据光刻系统中的成像构件的可再成像表面的系统和相应方法，而没有成形辊。在一个实施例中，该系统包括用于将润湿流体从液相转化为分散流体相的子系统，并且用于将包含分散流体相的润版液的分散流体的流动引导到可再成像的表面。阻尼流体直接在可再成像的表面上回流到液相。在另一个实施例中，连续的润版液体带可以直接施加到可再成像的表面。该实施例包括具有端口的主体结构，该端口用于将连续流体带中的阻尼流体直接传送到可再成像的表面，以及与主体结构相关联的机构，用于当可再成像的表面处于可再成像的表面时，将夹带的空气层剥离在可再成像的表面上运动。

6. 发明申请

US20100147686A1 SYSTEMS AND METHODS FOR TRANSPORTING PARTICLES 有权
公开(公告)号：US20100147686A1
公开(公告)日：2010-06-17
申请号：US12712897
申请日：2010-02-25
申请人： Armin R. Völkel , David Biegelsen , Philip D. Floyd , Greg Anderson , Fred Endicott , Eric Peeters , Jaan Noolandi , Karen A. Moffat , Peter M. Kazmaier , Maria McDougall , Daniel G. Bobrow
发明人： Armin R. Völkel , David Biegelsen , Philip D. Floyd , Greg Anderson , Fred Endicott , Eric Peeters , Jaan Noolandi , Karen A. Moffat , Peter M. Kazmaier , Maria McDougall , Daniel G. Bobrow
IPC分类号： C07K1/26
CPC分类号： B03C5/028
摘要： Various particle transport systems and components for use in such systems are described. The systems utilize one or more traveling wave grids to selectively transport, distribute, separate, or mix different populations of particles. Numerous systems configured for use in two dimensional and three dimensional particle transport are described.

7. 发明授权

US07440722B2 Xerography methods and systems employing addressable fusing of unfused toner image 有权
标题翻译：静电复印方法和系统采用可寻址的融合未图像的调色剂图像
公开(公告)号：US07440722B2
公开(公告)日：2008-10-21
申请号：US11000168
申请日：2004-11-30
申请人： Robert M. Lofthus , Kristine A. German , Donald M. Bott , John R. Andrews , David Biegelsen , Armin R. Völkel
发明人： Robert M. Lofthus , Kristine A. German , Donald M. Bott , John R. Andrews , David Biegelsen , Armin R. Völkel
IPC分类号： G03G15/20
CPC分类号： G03G15/2007
摘要： Methods and apparatus for performing addressable fusing and/or heating of a substrate undergoing xerographic processing are disclosed. The apparatus includes a fuser having an array of addressable heating elements in radiative communication with a substrate through a fuser roll or fuser belt. The array of addressable heating elements is operated to selectively heat portions of the substrate to achieve a desired effect on the substrate, such as changing its surface finish, or fusing unfused toner to the substrate. In the case of toner fusing, the array is operated such that substantially only an area covered by the unfused toner is heated. This eliminates the need for blanket fusing, and generally provides for greater flexibility in xerographically processing substrates. Apparatus and methods for performing two-sided selective fusing and/or heating are also disclosed.
摘要翻译：公开了用于执行可进行定影和/或加热进行静电印刷处理的基板的方法和装置。该设备包括具有可寻址加热元件的阵列的定影器，其通过定影辊或定影带与基底辐射连通。操作可寻址加热元件的阵列以选择性地加热基底的部分以在基底上获得期望的效果，例如改变其表面光洁度，或将未熔合的调色剂熔合到基底上。在调色剂定影的情况下，阵列的操作使得基本上只有被未熔融的调色剂覆盖的区域被加热。这消除了对毯子熔合的需要，并且通常提供在色彩处理衬底中更大的灵活性。还公开了用于进行双面选择性熔合和/或加热的设备和方法。

8. 发明申请

US20080152374A1 XEROGRAPHY METHODS AND SYSTEMS EMPLOYING ADDRESSABLE FUSING OF UNFUSED TONER IMAGE 失效
标题翻译：采用无偿图像融合的XEROGRAPHY方法和系统
公开(公告)号：US20080152374A1
公开(公告)日：2008-06-26
申请号：US12035945
申请日：2008-02-22
申请人： Robert M. Lofthus , Kristine A. German , Donald M. Bott , John R. Andrews , David Biegelsen , Armin R. Volkel
发明人： Robert M. Lofthus , Kristine A. German , Donald M. Bott , John R. Andrews , David Biegelsen , Armin R. Volkel
IPC分类号： G03G15/20
CPC分类号： G03G15/2007
摘要： Methods and apparatus for performing addressable fusing and/or heating of a substrate undergoing xerographic processing are disclosed. The apparatus includes a fuser having an array of addressable heating elements in radiative communication with a substrate through a fuser roll or fuser belt. The array of addressable heating elements is operated to selectively heat portions of the substrate to achieve a desired effect on the substrate, such as changing its surface finish, or fusing unfused toner to the substrate. In the case of toner fusing, the array is operated such that substantially only an area covered by the unfused toner is heated. This eliminates the need for blanket fusing, and generally provides for greater flexibility in xerographically processing substrates. Apparatus and methods for performing two-sided selective fusing and/or heating are also disclosed.
摘要翻译：公开了用于执行可进行定影和/或加热进行静电印刷处理的基板的方法和装置。该设备包括具有可寻址加热元件的阵列的定影器，其通过定影辊或定影带与基底辐射连通。操作可寻址加热元件的阵列以选择性地加热基底的部分以在基底上获得期望的效果，例如改变其表面光洁度，或将未熔合的调色剂熔合到基底上。在调色剂定影的情况下，阵列的操作使得基本上只有被未熔融的调色剂覆盖的区域被加热。这消除了对毯子熔合的需要，并且通常提供在色彩处理衬底中更大的灵活性。还公开了用于进行双面选择性熔合和/或加热的设备和方法。

9. 发明授权

US07374603B2 Particle transport and near field analytical detection 失效
标题翻译：粒子运输和近场分析检测
公开(公告)号：US07374603B2
公开(公告)日：2008-05-20
申请号：US11803470
申请日：2007-05-15
申请人： David Biegelsen
发明人： David Biegelsen
IPC分类号： B03C3/34 , B03C3/47
CPC分类号： G01N15/1456 , B03C5/02 , G01N1/2202 , G01N15/0656 , G01N2015/0042 , G01N2015/0288 , G01N2015/149
摘要： Particle collection, transport, and detection systems are disclosed. The systems are uniquely adapted for collecting or concentrating particles from a flowing medium and then transporting the collected particles to a desired location or for subsequent analysis. Electrostatic traveling wave grids can be used in conjunction with sample concentrators.
摘要翻译：公开了颗粒收集，运输和检测系统。该系统独特地用于从流动介质中收集或浓缩颗粒，然后将收集的颗粒输送到期望的位置或用于随后的分析。静电行波网格可与样品浓缩器配合使用。

10. 发明申请

US20070160373A1 Distributed illumination and sensing system 审中-公开
标题翻译：分布式照明和感应系统
公开(公告)号：US20070160373A1
公开(公告)日：2007-07-12
申请号：US11317215
申请日：2005-12-22
申请人： David Biegelsen , Daniel Bobrow , James Reich , Daniel Greene
发明人： David Biegelsen , Daniel Bobrow , James Reich , Daniel Greene
IPC分类号： H04B10/00 , H01L27/00
CPC分类号： H05B37/0245 , H05B37/0272
摘要： A method and system of distributed illumination and sensing, the system including devices, each device including an emitter to emit at least one of light and sound, a sensor to receive an indirect emission, and a controller to determine the existence and/or relative location of at least one of the other devices in response to the indirect emission.
摘要翻译：分布式照明和感测的方法和系统，该系统包括设备，每个设备包括发射光和声音中的至少一个的发射器，用于接收间接发射的传感器，以及用于确定存在和/或相对位置的控制器的至少一个其他装置响应于间接发射。

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