专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050101623A1 Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors 审中-公开
标题翻译： β-咔啉化合物及其类似物作为丝裂原活化蛋白激酶活化蛋白激酶-2抑制剂
公开(公告)号：US20050101623A1
公开(公告)日：2005-05-12
申请号：US10894594
申请日：2004-07-20
申请人： Marvin Meyers , David Anderson , Shridhar Hegde , John Trujillo , David Reitz , Matthew Mahoney , William Vernier , Ingrid Buchler , Kun Wu
发明人： Marvin Meyers , David Anderson , Shridhar Hegde , John Trujillo , David Reitz , Matthew Mahoney , William Vernier , Ingrid Buchler , Kun Wu
IPC分类号： A61K20060101 , A61K31/40 , A61K31/403 , A61K31/407 , A61K31/4745 , A61K31/55 , C07D209/82 , C07D209/94 , C07D471/02 , C07D471/14
CPC分类号： A61K31/40 , C07D471/04 , C07D471/14 , C07D471/18 , Y02A50/475
摘要： The present invention provides novel bridged beta-carboline compounds that are capable of inhibiting mitogen activated protein kinase-activated protein kinase-2 and analogues thereof and pharmaceutical compositions and kits that include these compounds.
摘要翻译：本发明提供能够抑制丝裂原活化蛋白激酶活化蛋白激酶-2及其类似物的新型桥连β-咔啉化合物和包括这些化合物的药物组合物和试剂盒。

2. 发明申请

US20050137220A1 Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors 审中-公开
标题翻译： β-咔啉化合物及其类似物作为丝裂原活化蛋白激酶活化蛋白激酶-2抑制剂
公开(公告)号：US20050137220A1
公开(公告)日：2005-06-23
申请号：US10895187
申请日：2004-07-20
申请人： David Anderson , Ingrid Buchler , Shridhar Hegde , Matthew Mahoney , Marvin Meyers , David Reitz , John Trujillo , William Vernier , Kun Wu
发明人： David Anderson , Ingrid Buchler , Shridhar Hegde , Matthew Mahoney , Marvin Meyers , David Reitz , John Trujillo , William Vernier , Kun Wu
IPC分类号： A61K20060101 , A61K31/40 , A61K31/403 , A61K31/407 , A61K31/4745 , A61K31/55 , C07D209/82 , C07D209/94 , C07D471/02 , C07D471/14
CPC分类号： A61K31/40 , C07D471/04 , C07D471/14 , C07D471/18 , Y02A50/475
摘要： A method is described for inhibiting mitogen activated protein kinase-activated protein kinase-2 in a subject in need of such inhibition, where the method involves administering to the subject a beta-carboline MK-2 inhibiting compound, or a pharmaceutically acceptable salt thereof.
摘要翻译：描述了一种在需要这种抑制的受试者中抑制丝裂原活化蛋白激酶活化蛋白激酶-2的方法，其中该方法涉及向受试者施用β-咔啉MK-2抑制化合物或其药学上可接受的盐。

3. 发明申请

US20080113971A1 PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS 审中-公开
标题翻译：吡咯化合物作为蛋白激酶抑制剂
公开(公告)号：US20080113971A1
公开(公告)日：2008-05-15
申请号：US11958229
申请日：2007-12-17
申请人： Cathleen Hanau , Serena Mershon , Matthew Graneto , Marvin Meyers , Ingrid Buchler , Shridhar Hegde , Kun Wu , Shuang Liu
发明人： Cathleen Hanau , Serena Mershon , Matthew Graneto , Marvin Meyers , Ingrid Buchler , Shridhar Hegde , Kun Wu , Shuang Liu
IPC分类号： A61K31/551 , A61K31/498 , C07D487/04
CPC分类号： C07D471/04 , C07D401/04 , C07D401/14 , C07D471/14 , C07D487/04 , C07D513/04 , C07D519/00
摘要： Compounds are described which inhibit mitogen activated protein kinase-activated protein kinase-2 (MK-2). Methods of making such compounds are described, as well as a method of using them for the inhibition of MK-2, and for the prevention or treatment of a disease or disorder that is mediated by TNFα, where the method involves administering to the subject an MK-2 inhibiting compound of the present invention. Pharmaceutical compositions and kits which contain the present MK-2 inhibiting compounds are also described.
摘要翻译：描述了抑制丝裂原活化蛋白激酶活化蛋白激酶-2（MK-2）的化合物。描述了制备这些化合物的方法，以及使用它们用于抑制MK-2的方法，以及用于预防或治疗由TNFα介导的疾病或病症的方法，其中所述方法涉及对受试者施用本发明的MK-2抑制化合物。还描述了含有本发明的MK-2抑制化合物的药物组合物和试剂盒。

4. 发明授权

US08694604B2 Accurate search results while honoring content limitations 有权
标题翻译：精确的搜索结果，同时满足内容限制
公开(公告)号：US08694604B2
公开(公告)日：2014-04-08
申请号：US13217549
申请日：2011-08-25
申请人： Charles E. Cummins , Justin Hamilton , Yue Ma , Hua Ding , Xiaowei Sheng , Bing Lang , Kun Wu
发明人： Charles E. Cummins , Justin Hamilton , Yue Ma , Hua Ding , Xiaowei Sheng , Bing Lang , Kun Wu
IPC分类号： G06F17/30
CPC分类号： G06F17/30867
摘要： Accurate search results are provided while still honoring content limitations. Content responsive to search, whose presentation is prevented by content limitations is presented in an obscured manner, notifying the user of the existence of the content, while not enabling discerning of details, thereby honoring the content limitations. Attempted user interaction with obscured content acts as an entry point to changing the content limitations, including presenting user notifications of the content limitations and presenting an option to change the content limitations to allow for the unobscured presentation of the obscured content. Graphical content can be obscured by applying graphical modifications to generate new, obscured content that provides only a vague resemblance to the original, including jittering pixels, or other subcomponents, the applying of Gaussian blurs, and pixelization.
摘要翻译：提供准确的搜索结果，同时保持内容限制。通过内容限制来防止其呈现的响应的内容以不透明的方式呈现，通知用户存在内容，而不能识别细节，从而尊重内容限制。尝试与模糊内容的用户交互作为改变内容限制的切入点，包括呈现用户对内容限制的通知，并提供更改内容限制的选项，以允许隐藏的内容的视差显示。可以通过应用图形修改来生成图形内容，以生成新的，模糊的内容，仅提供与原始模糊相似的内容，包括抖动像素或其他子组件，应用高斯模糊和像素化。

5. 发明申请

US20130054572A1 ACCURATE SEARCH RESULTS WHILE HONORING CONTENT LIMITATIONS 有权
标题翻译：在获得内容限制时精确搜索结果
公开(公告)号：US20130054572A1
公开(公告)日：2013-02-28
申请号：US13217549
申请日：2011-08-25
申请人： Charles E. Cummins , Justin Hamilton , Yue Ma , Hua Ding , Xiaowei Sheng , Bing Lang , Kun Wu
发明人： Charles E. Cummins , Justin Hamilton , Yue Ma , Hua Ding , Xiaowei Sheng , Bing Lang , Kun Wu
IPC分类号： G06F17/30
CPC分类号： G06F17/30867
摘要： Accurate search results are provided while still honoring content limitations. Content responsive to search, whose presentation is prevented by content limitations is presented in an obscured manner, notifying the user of the existence of the content, while not enabling discerning of details, thereby honoring the content limitations. Attempted user interaction with obscured content acts as an entry point to changing the content limitations, including presenting user notifications of the content limitations and presenting an option to change the content limitations to allow for the unobscured presentation of the obscured content. Graphical content can be obscured by applying graphical modifications to generate new, obscured content that provides only a vague resemblance to the original, including jittering pixels, or other subcomponents, the applying of Gaussian blurs, and pixelization.
摘要翻译：提供准确的搜索结果，同时保持内容限制。通过内容限制来防止其呈现的响应的内容以不透明的方式呈现，通知用户存在内容，而不能识别细节，从而尊重内容限制。尝试与模糊内容的用户交互作为改变内容限制的切入点，包括呈现用户对内容限制的通知，并提供更改内容限制的选项，以允许隐藏的内容的视差显示。可以通过应用图形修改来生成图形内容，以生成新的，模糊的内容，仅提供与原始模糊相似的内容，包括抖动像素或其他子组件，应用高斯模糊和像素化。

6. 发明授权

US07284028B2 Comparator eliminating need for one's complement logic for signed numbers 失效
标题翻译：比较器消除了对符号数字的补码逻辑的需要
公开(公告)号：US07284028B2
公开(公告)日：2007-10-16
申请号：US10287108
申请日：2002-11-01
申请人： Wei Hwang , Kun Wu
发明人： Wei Hwang , Kun Wu
IPC分类号： G06F7/50 , G06F7/02
CPC分类号： G06F7/026
摘要： An apparatus and method for providing high speed computing power with efficient power consumption in a computing environment comprising a comparator with at least one input feed; a sign selector in electronic communication with the comparator; and result flag generator in electronic communication with both the sign selector and the comparator. The sign selector has input data feeds and an equivalent number of dedicated indicators for identifying signed numbers from unsigned numbers for each of the input data feeds. The result flag generator receives a first resultant feed from the comparator and a second resultant feed from the sign selector. The sign selector can be designed to provide a resultant output. The resultant output is generated after collective operations have been performed on the input feeds and selectively on other feeds such as a sign feed and an Ini feed.
摘要翻译：一种用于在包括具有至少一个输入馈送的比较器的计算环境中提供高效率功耗的高速计算能力的装置和方法; 与比较器进行电子通信的符号选择器; 和结果标志发生器与符号选择器和比较器进行电子通信。符号选择器具有输入数据馈送和等效数量的专用指示符，用于从每个输入数据馈送的无符号数中识别有符号数字。结果标志发生器从比较器接收第一个合成的馈送，并从该符号选择器接收第二个合成的馈送。符号选择器可以设计成提供合成输出。在对输入馈送进行集体操作并选择性地在其他馈送（例如符号馈送和Ini馈送）上产生结果输出。

7. 发明申请

US20050216873A1 Method of checking the layout versus the schematic of multi-fingered MOS transistor layouts using a sub-circuit based extraction 失效
标题翻译：使用基于子电路的提取来检查布局与多指MOS晶体管布局的示意图的方法
公开(公告)号：US20050216873A1
公开(公告)日：2005-09-29
申请号：US10807478
申请日：2004-03-23
申请人： Raminderpal Singh , Yue Tan , Jean-Oliver Plouchart , Lawrence Wagner , Mohamed Talbi , John Safran , Kun Wu
发明人： Raminderpal Singh , Yue Tan , Jean-Oliver Plouchart , Lawrence Wagner , Mohamed Talbi , John Safran , Kun Wu
IPC分类号： G06F17/50
CPC分类号： G06F17/5081 , G06F17/5022
摘要： A sub-circuit based extraction method which extracts a multi-finger MOS transistor directly as a sub-circuit is described. By adding three marking layers, the method provides the layout extracted netlist with a complete list of device geometric parameters corresponding to the device properties as presented in the sub-circuit model based schematic netlist. By performing a layout-versus-schematic comparison based on all geometric parameters extracted, the layout checking is performed in a complete and accurate way where each device parameter is checked against the corresponding design schematic. This complete and accurate geometric parameter comparison enhances the confidence level of the layout physical verification.
摘要翻译：描述了一种基于子电路的提取方法，其直接提取多指状MOS晶体管作为子电路。通过添加三个标记层，该方法为布局提取的网表提供了与基于子电路模型的示意图网表中所示的设备属性对应的设备几何参数的完整列表。通过基于提取的所有几何参数执行布局与原理图比较，以完整和准确的方式执行布局检查，其中根据相应的设计原理图检查每个设备参数。这种完整和准确的几何参数比较增强了布局物理验证的置信度。

8. 发明申请

US20140020135A1 Novel Use of a Dense and Erect Panicle 1 Gene in Improving Nitrogen Utilization Efficiency 审中-公开
标题翻译：新型使用密集和直立的穗1基因提高氮利用效率
公开(公告)号：US20140020135A1
公开(公告)日：2014-01-16
申请号：US13982229
申请日：2012-01-27
申请人： Xiangdong Fu , Kun Wu , Qian Qian , Chengwei Zhang , Xueying Liu , Shuansuo Wang
发明人： Xiangdong Fu , Kun Wu , Qian Qian , Chengwei Zhang , Xueying Liu , Shuansuo Wang
IPC分类号： C12N15/82
CPC分类号： C12N15/8243 , C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The present invention provides methods of increasing nitrogen utilization efficiency (NUE) in a transgenic plant comprising the introduction of a nucleic acid encoding a dep1 polypeptide into a plant to produce a transgenic plant that expresses the nucleic acid to produce the dep1 polypeptide, thereby resulting in an increased NUE as compared with a control plant. Also provided are methods of increasing NUE in a plant comprising reducing the amount and/or activity of a DEP1 polypeptide.
摘要翻译：本发明提供在转基因植物中提高氮利用效率（NUE）的方法，包括将编码dep1多肽的核酸引入植物中以产生表达该核酸以产生dep1多肽的转基因植物，由此导致与对照厂相比增加了NUE。还提供了增加植物中NUE的方法，包括降低DEP1多肽的量和/或活性。

9. 发明授权

US08090679B2 Method for measuring web site performance 有权
标题翻译：衡量网站性能的方法
公开(公告)号：US08090679B2
公开(公告)日：2012-01-03
申请号：US12165600
申请日：2008-06-30
申请人： Yue Zhuge , Kun Wu
发明人： Yue Zhuge , Kun Wu
IPC分类号： G06F17/30
CPC分类号： G06F11/3495 , G06F11/3419 , G06F2201/875
摘要： An approach for systematically and objectively assessing the health of a web site, or other complex system, using two layers of information. A scoring method is used to provide an objective qualitative judgment, together with detailed areas of analysis if desired. A set of metrics is identified, and a health score for each metric is calculated based upon assessment parameters or angles, based upon the actual data and upon the expectations. The overall health score of the system is then calculated as a composite metric based upon the individual metric health scores. A total score, together with a visual representation of the individual metric scores, is presented to the end user. The two layers of information utilized in the general framework include the domain (which determines the set of metrics and assessment parameters, e.g., web site analysis) and the model (or processing desired, e.g., a scoring model or alert model).
摘要翻译：一种使用两层信息系统和客观地评估网站或其他复杂系统的健康状况的方法。使用评分方法提供客观的定性判断，以及如果需要的详细的分析领域。确定一组度量，并且基于评估参数或角度，基于实际数据和预期来计算每个度量的健康得分。然后，系统的整体健康得分将根据个体度量健康评分计算为综合指标。总分数以及个体度量分数的视觉表示被呈现给最终用户。在一般框架中使用的两层信息包括域（其确定度量和评估参数的集合，例如网站分析）和模型（或期望的处理，例如评分模型或警报模型）。

10. 发明申请

US20100153890A1 Method, Apparatus and Computer Program Product for Providing a Predictive Model for Drawing Using Touch Screen Devices 审中-公开
标题翻译：用于提供使用触摸屏设备绘制的预测模型的方法，设备和计算机程序产品
公开(公告)号：US20100153890A1
公开(公告)日：2010-06-17
申请号：US12332675
申请日：2008-12-11
申请人： Hao Wang , Kun Wu
发明人： Hao Wang , Kun Wu
IPC分类号： G06F3/033
CPC分类号： G06F3/011 , G06F3/04845 , G06F3/04883 , G06F2203/011 , G06T11/00 , H04L67/04
摘要： An apparatus for providing a predictive model for use with touch screen devices may include a processor. The processor may be configured to identify a stroke event received at a touch screen display, evaluate an environmental parameter corresponding to the touch screen display to determine a scenario based on the environmental parameter, and generate a graphic output corresponding to the identified stroke event for the scenario determined. A corresponding method and computer program product are also provided.
摘要翻译：用于提供与触摸屏设备一起使用的预测模型的装置可以包括处理器。处理器可以被配置为识别在触摸屏显示器处接收到的笔划事件，评估与触摸屏显示相对应的环境参数以基于环境参数来确定场景，并且生成对应于所识别的笔画事件的图形输出情景确定。还提供了相应的方法和计算机程序产品。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式