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1. 发明授权

US06317625B1 Method and apparatus for increasing the low frequency dynamic range of a system for measuring physiological signals with an implantable medical device 失效
标题翻译：用于通过可植入医疗装置增加用于测量生理信号的系统的低频动态范围的方法和装置
公开(公告)号：US06317625B1
公开(公告)日：2001-11-13
申请号：US09713455
申请日：2000-11-15
申请人： Dana J. Olson , David W. Van Ess , Robert W. Stadler , Steven N. Lu , Jeffrey D. Wilkinson , Tara N. Ptak
发明人： Dana J. Olson , David W. Van Ess , Robert W. Stadler , Steven N. Lu , Jeffrey D. Wilkinson , Tara N. Ptak
IPC分类号： A61B50402
CPC分类号： A61B5/0428 , A61B5/7232 , A61N1/3925 , Y10S128/901 , Y10S128/902
摘要： A signal measuring system for use with an Implantable Medical Device (IMD) is provided for measuring physiologic signals having a relatively large effective dynamic range. In one embodiment, the system includes a High-Pass Filter (HPF), an Analog-to-Digital Converter (ADC), a Decimation Filter (DF), and a Compensation Filter (CF). The HPF receives an input signal that includes both the baseline wander imposed on a physiological signal. According to one aspect of the invention, the HPF attenuates low frequency components of the input signal, including a portion of the frequency band within the desired output signal bandwidth. The ADC then oversamples the output signal of the HPF. The DF receives the output samples from the ADC and generates output samples at rate that is at least twice the maximum frequency of the desired output signal. The CF then amplifies the low frequency end of the DF output samples. The gain and cutoff frequency of the CF are selected to offset the HPF attenuation of those low frequency components of the input signal below the cutoff frequency of the HPF and above the minimum frequency of the desired output signal. In one embodiment, the DF and CF are implemented by a processing circuit executing programmed instructions. The processing circuit may be included within the IMD, or may be partially or fully implemented within a device that is external to the IMD.
摘要翻译：提供了一种用于可植入医疗器械（IMD）的信号测量系统，用于测量具有相对较大有效动态范围的生理信号。在一个实施例中，该系统包括高通滤波器（HPF），模数转换器（ADC），抽取滤波器（DF）和补偿滤波器（CF）。 HPF接收包括施加在生理信号上的基线漂移的输入信号。根据本发明的一个方面，HPF衰减输入信号的低频分量，包括期望输出信号带宽内的一部分频带。 ADC然后对HPF的输出信号进行过采样。 DF从ADC接收输出采样，并以至少是所需输出信号的最大频率的两倍的速率生成输出采样。 CF然后放大DF输出样本的低频端。选择CF的增益和截止频率以将输入信号的那些低频分量的HPF衰减降低到低于HPF的截止频率并且高于所需输出信号的最小频率。在一个实施例中，DF和CF由执行编程指令的处理电路实现。处理电路可以包括在IMD内，或者可以部分地或完全地实现在IMD外部的设备中。

2. 发明授权

US06249696B1 Method and apparatus for increasing the low frequency dynamic range of a digital ECG measuring system 有权
标题翻译：用于增加数字ECG测量系统的低频动态范围的方法和装置
公开(公告)号：US06249696B1
公开(公告)日：2001-06-19
申请号：US09232044
申请日：1999-01-15
申请人： Dana J. Olson , David W. Van Ess
发明人： Dana J. Olson , David W. Van Ess
IPC分类号： A61B50402
CPC分类号： A61B5/0428 , A61B5/7232 , A61N1/3925 , Y10S128/901 , Y10S128/902
摘要： An ECG signal measuring system uses low frequency compression/enhancement techniques combined with dither techniques to effectively increase the dynamic range while maintaining resolution. This aspect of the present invention is achieved without increasing the number of bits of the ADC. The system includes a HPF, an ADC, a decimation filter (DF), and a compensation filter (CF). The HPF receives an input signal (i.e., the bias current combined with ECG input signal) and attenuates the low frequency components of the input signal, including a portion of the frequency band within the desired ECG frequency band. The ADC oversamples the output signal of the HPF. The DF receives the output samples of the ADC and generates output samples at rate that is at least twice the maximum frequency of the desired ECG output signal. The CF amplifies the low frequency end of the DF output samples. The gain and cutoff frequency of the CF are set to offset the HPF's attenuation of those low frequency components of the input signal below the minimum frequency of the desired ECG output signal. System noise can be used as the dither. Consequently, the ECG output signal remains within the dynamic range of the system.
摘要翻译： ECG信号测量系统使用低频压缩/增强技术结合抖动技术来有效地增加动态范围，同时保持分辨率。在不增加ADC的位数的情况下实现本发明的这个方面。该系统包括HPF，ADC，抽取滤波器（DF）和补偿滤波器（CF）。 HPF接收输入信号（即，与ECG输入信号组合的偏置电流），并且衰减输入信号的低频分量，包括期望的ECG频带内的频带的一部分。 ADC过滤采样HPF的输出信号。 DF接收ADC的输出采样，并以至少是所需ECG输出信号的最大频率的两倍的速率生成输出采样。 CF放大DF输出样本的低频端。 CF的增益和截止频率被设置为将输入信号的那些低频分量的HPF衰减降低到期望的ECG输出信号的最小频率以下。系统噪声可用作抖动。因此，ECG输出信号保持在系统的动态范围内。

3. 发明授权

US07162306B2 Internal medical device communication bus 有权
标题翻译：内部医疗器械通讯总线
公开(公告)号：US07162306B2
公开(公告)日：2007-01-09
申请号：US09992708
申请日：2001-11-19
申请人： Glen D. Caby , James S. Neumiller , Jyhlin Chang , Curtis R. Jordan , Dana J. Olson , Ward A. Silver , Scott O. Schweizer
发明人： Glen D. Caby , James S. Neumiller , Jyhlin Chang , Curtis R. Jordan , Dana J. Olson , Ward A. Silver , Scott O. Schweizer
IPC分类号： A61N1/39
CPC分类号： A61N1/08 , A61N1/3956
摘要： In general, the invention facilitates improved inter-module communication within a medical device system, such as an automated external defibrillator (AED), by using a serial data interface based on the USB specification to transfer data between modules. As a result, data transmission rates may be improved significantly, thereby providing ample communication bandwidth for a variety of medical device applications. Further, the serial interconnect nature of the USB interface reduces the number of physical interconnects that are needed to support the interface, thereby reducing the design constraints on the medical device system.
摘要翻译：通常，本发明通过使用基于USB规范的串行数据接口来在模块之间传输数据来促进医疗设备系统（例如自动化外部除颤器（AED））内的模块间通信。结果，可以显着地提高数据传输速率，从而为各种医疗设备应用提供充足的通信带宽。此外，USB接口的串行互连性质减少了支持接口所需的物理互连的数量，从而减少了医疗设备系统上的设计限制。

4. 发明授权

US06823209B2 Electrocardiogram filter 有权
标题翻译：心电图滤波器
公开(公告)号：US06823209B2
公开(公告)日：2004-11-23
申请号：US09982111
申请日：2001-10-19
申请人： Dana J. Olson , Scott O. Schweizer , Tyler R. Hart , David Van Ess
发明人： Dana J. Olson , Scott O. Schweizer , Tyler R. Hart , David Van Ess
IPC分类号： A61B50402
CPC分类号： A61B5/0424 , A61B5/04017 , A61N1/3702
摘要： The invention presents techniques for identifying signals detected by electrodes on the body of a patient as part of a reading of the patient's electrocardiogram. A signal processor digitally filters the signal from the body, resulting in an electrocardiogram signal and a signal that identifies the presence and timing of signals from a pacemaker in the body. Other signals, such as a signal that reflects the quality of the electrical connection of the electrode to the body, may also be obtained by digital filtering.
摘要翻译：本发明提供了用于识别由患者身体上的电极检测的信号作为患者心电图读数的一部分的技术。信号处理器对来自身体的信号进行数字滤波，产生心电图信号和识别来自体内起搏器的信号的存在和定时的信号。也可以通过数字滤波来获得诸如反映电极与身体的电连接的质量的信号的其它信号。

5. 发明授权

US06280391B1 Method and apparatus for removing baseline wander from an egg signal 有权
标题翻译：从卵信号中去除基线漂移的方法和装置
公开(公告)号：US06280391B1
公开(公告)日：2001-08-28
申请号：US09246625
申请日：1999-02-08
申请人： Dana J. Olson , Dennis R. Seguine
发明人： Dana J. Olson , Dennis R. Seguine
IPC分类号： B61B50428
CPC分类号： H03H17/06 , A61B5/0428 , H03H17/02
摘要： A baseline wander filter (BWF) with linear phase response for an ECG signal measuring system includes two cascaded box car FIR filters to estimate the baseline wander. The cascaded box car filters form, in effect, a triangular FIR filter that generates a weighted sliding window average of the input samples to serve as the estimated baseline wander. The estimated baseline wander samples generated by the BWF are then subtracted from the corresponding input ECG samples. The boxcar filters can be designed to avoid multiplication by adding the samples and dividing the resulting sum by the number of coefficients. By choosing the number of coefficients as a power of two, binary division can be performed by shifting the bits of the resulting sum to the right. Accordingly, the present invention avoids the relatively large computational load of conventional FIR filter-based systems. The BWF can be implemented in software in which each boxcar filter uses an accumulator data structure that generates the sum of the previous N samples. When adding the next sample to the sum, it subtracts the Nth previous sample. The output sample of the BWF is equal to the value in the sum buffer, appropriately shifted.
摘要翻译：具有ECG信号测量系统的线性相位响应的基线漂移滤波器（BWF）包括两个级联的盒车FIR滤波器以估计基线漂移。级联盒式汽车滤波器实际上形成三角FIR滤波器，其产生输入样本的加权滑动窗口平均值，以用作估计的基线漂移。然后从相应的输入ECG样本中减去由BWF产生的估计的基线漂移样本。盒式滤波器可以设计成避免乘以相加样本并将得到的和除以系数数。通过选择系数的数量作为2的幂，可以通过将所得和的位向右移位来执行二进制除法。因此，本发明避免了传统的基于FIR滤波器的系统的相对较大的计算量。 BWF可以在软件中实现，其中每个盒式滤波器使用产生先前N个样本的和的累加器数据结构。当将下一个样本添加到和时，它将减去第N个先前的样本。 BWF的输出样本等于和缓冲区中的值，适当偏移。

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