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1. 发明申请

US20110160551A1 METHOD AND APPARATUS FOR MORPHOLOGY-BASED ARRHYTHMIA CLASSIFICATION USING CARDIAC AND OTHER PHYSIOLOGICAL SIGNALS 有权
标题翻译：使用心脏和其他生理信号进行形态学基于ARRHYTHMIA分类的方法和装置
公开(公告)号：US20110160551A1
公开(公告)日：2011-06-30
申请号：US13043346
申请日：2011-03-08
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61B5/02
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal, a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板的形态特征之间的相关性的相关系数波形通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

2. 发明申请

US20090292332A1 METHOD AND APPARATUS FOR MORPHOLOGY-BASED ARRHYTHMIA CLASSIFICATION USING CARDIAC AND OTHER PHYSIOLOGICAL SIGNALS 有权
标题翻译：使用心脏和其他生理信号进行形态学基于ARRHYTHMIA分类的方法和装置
公开(公告)号：US20090292332A1
公开(公告)日：2009-11-26
申请号：US12536828
申请日：2009-08-06
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61N1/39 , A61B5/02 , A61B5/0205
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数。通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

3. 发明授权

US07582061B2 Method and apparatus for morphology-based arrhythmia classification using cardiac and other physiological signals 有权
标题翻译：使用心脏和其他生理信号进行形态学心律失常分类的方法和装置
公开(公告)号：US07582061B2
公开(公告)日：2009-09-01
申请号：US11316332
申请日：2005-12-22
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61B5/02
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数。通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

4. 发明申请

US20070149890A1 Method and apparatus for morphology-based arrhythmia classification using cardiac and other physiological signals 有权
标题翻译：使用心脏和其他生理信号进行形态学心律失常分类的方法和装置
公开(公告)号：US20070149890A1
公开(公告)日：2007-06-28
申请号：US11316332
申请日：2005-12-22
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61B5/04
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数。通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

5. 发明申请

US20070142736A1 Discriminating polymorphic and monomorphic cardiac rhythms using template generation 有权
标题翻译：使用模板生成区分多态性和单态心律
公开(公告)号：US20070142736A1
公开(公告)日：2007-06-21
申请号：US11312279
申请日：2005-12-20
申请人： Shelley Cazares , Carlos Ricci , Dan Li , Yayun Lin , Yi Zhang , Jaeho Kim , Joseph Bocek
发明人： Shelley Cazares , Carlos Ricci , Dan Li , Yayun Lin , Yi Zhang , Jaeho Kim , Joseph Bocek
IPC分类号： A61B5/04
CPC分类号： A61N1/3622 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/7264 , A61N1/3702 , A61N1/3962
摘要： Cardiac arrhythmias are classified based on the morphology of the arrhythmia episode beats. Templates are formed using morphological features of the cardiac beats of the episode. The arrhythmia episode is classified as a monomorphic tachyarrhythmia or polymorphic tachyarrhythmia based on the one or more templates. The arrhythmia episode may be classified based on a number templates formed from the arrhythmia episode. The templates are formed by determining a measure of similarity between morphological features of a cardiac beat to a template. The similarities can be determined based on a pairing rule that determines which beat morphologies are compared. Selection of therapy for treating the arrhythmia episode may depend on the historical success of a therapy at mitigating previous arrhythmias of the same type as the arrhythmia episode.
摘要翻译：心律失常根据心律失常发作的形态进行分类。使用情节心脏搏动的形态学特征形成模板。基于一个或多个模板，心律失常发作被分类为单形性快速性心律失常或多态性快速性心律失常。心律失常发作可以基于由心律失常发作形成的数字模板进行分类。模板通过确定心跳的形态特征与模板之间的相似性的度量来形成。可以基于确定哪些拍子形态进行比较的配对规则来确定相似度。选择治疗心律失常发作的治疗可能取决于治疗在缓解与心律失常事件相同类型的以前心律失常方面的历史成功。

6. 发明授权

US08532762B2 Discriminating polymorphic and monomorphic cardiac rhythms using template generation 有权
标题翻译：使用模板生成区分多态性和单态心律
公开(公告)号：US08532762B2
公开(公告)日：2013-09-10
申请号：US11312279
申请日：2005-12-20
申请人： Shelley Cazares , Carlos Ricci , Dan Li , Yayun Lin , Yi Zhang , Jaeho Kim , Joseph Bocek
发明人： Shelley Cazares , Carlos Ricci , Dan Li , Yayun Lin , Yi Zhang , Jaeho Kim , Joseph Bocek
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/7264 , A61N1/3702 , A61N1/3962
摘要： Cardiac arrhythmias are classified based on the morphology of the arrhythmia episode beats. Templates are formed using morphological features of the cardiac beats of the episode. The arrhythmia episode is classified as a monomorphic tachyarrhythmia or polymorphic tachyarrhythmia based on the one or more templates. The arrhythmia episode may be classified based on a number templates formed from the arrhythmia episode. The templates are formed by determining a measure of similarity between morphological features of a cardiac beat to a template. The similarities can be determined based on a pairing rule that determines which beat morphologies are compared. Selection of therapy for treating the arrhythmia episode may depend on the historical success of a therapy at mitigating previous arrhythmias of the same type as the arrhythmia episode.
摘要翻译：心律失常根据心律失常发作的形态进行分类。使用情节心脏搏动的形态学特征形成模板。基于一个或多个模板，心律失常发作被分类为单形性快速性心律失常或多态性快速性心律失常。心律失常发作可以基于由心律失常发作形成的数字模板进行分类。模板通过确定心跳的形态特征与模板之间的相似性的度量来形成。可以基于确定哪些拍子形态进行比较的配对规则来确定相似度。选择治疗心律失常发作的治疗可能取决于治疗在缓解与心律失常事件相同类型的以前心律失常方面的历史成功。

7. 发明授权

US08506500B2 Method and apparatus for morphology-based arrhythmia classification using cardiac and other physiological signals 有权
标题翻译：使用心脏和其他生理信号进行形态学心律失常分类的方法和装置
公开(公告)号：US08506500B2
公开(公告)日：2013-08-13
申请号：US13043346
申请日：2011-03-08
申请人： Dan Li , Shelley M. Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley M. Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61B5/0472 , A61B5/02
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal, a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板的形态特征之间的相关性的相关系数波形通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

8. 发明授权

US07912545B2 Method and apparatus for morphology-based arrhythmia classification using cardiac and other physiological signals 有权
标题翻译：使用心脏和其他生理信号进行形态学心律失常分类的方法和装置
公开(公告)号：US07912545B2
公开(公告)日：2011-03-22
申请号：US12536828
申请日：2009-08-06
申请人： Dan Li , Shelley M. Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley M. Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61N1/362 , A61B5/04
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal, a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板的形态特征之间的相关性的相关系数波形通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

9. 发明申请

US20100121209A1 Arrhythmia Discrimination Based on Determination of Rate Dependency 审中-公开
标题翻译：基于速率依赖性确定的心律失常鉴别
公开(公告)号：US20100121209A1
公开(公告)日：2010-05-13
申请号：US12686122
申请日：2010-01-12
申请人： Shelley Cazares , Jaeho Kim , Yayun Lin , Carlos Ricci
发明人： Shelley Cazares , Jaeho Kim , Yayun Lin , Carlos Ricci
IPC分类号： A61B5/0464
CPC分类号： A61B5/0464 , A61B5/04525 , A61B5/7264
摘要： Cardiac systems and methods provide for discriminating between supraventricular tachyarrhythmia and ventricular tachyarrhythmia based on a determination that the patient's supraventricular rhythm exhibits rate dependency. One approach involves determining if a patient's supraventricular rhythm exhibits rate dependent morphology. If the patient's supraventricular rhythm is determined to exhibit rate dependent morphology, an implantable device classifies a detected tachyarrhythmia episode based on one or more templates selected from a plurality of rate-indexed templates stored in the device. Determining if the supraventricular rhythm exhibits rate dependent morphology may also include determining one or more rates at which the rate dependent morphology occurs.
摘要翻译：心脏系统和方法基于确定患者的室上节律表现出速率依赖性，确定了室上性快速性心律失常与室性快速性心律失常之间的区别。一种方法涉及确定患者的室上节律是否表现出速率依赖性形态。如果确定患者的室上节律表现出与速率相关的形态，则可植入装置基于从存储在装置中的多个速率索引模板中选择的一个或多个模板来分类检测到的快速性心律失常发作。确定室性心律显示出速率依赖性形态还可以包括确定发生速率依赖形态的一个或多个速率。

10. 发明授权

US09119547B2 Arrhythmia discrimination based on determination of rate dependency 有权
标题翻译：基于速率依赖性确定的心律失常辨别
公开(公告)号：US09119547B2
公开(公告)日：2015-09-01
申请号：US12686122
申请日：2010-01-12
申请人： Shelley Cazares , Jaeho Kim , Yayun Lin , Carlos Alberto Ricci
发明人： Shelley Cazares , Jaeho Kim , Yayun Lin , Carlos Alberto Ricci
IPC分类号： A61B5/0464 , A61B5/0452 , A61B5/00
CPC分类号： A61B5/0464 , A61B5/04525 , A61B5/7264
摘要： Cardiac systems and methods provide for discriminating between supraventricular tachyarrhythmia and ventricular tachyarrhythmia based on a determination that the patient's supraventricular rhythm exhibits rate dependency. One approach involves determining if a patient's supraventricular rhythm exhibits rate dependent morphology. If the patient's supraventricular rhythm is determined to exhibit rate dependent morphology, an implantable device classifies a detected tachyarrhythmia episode based on one or more templates selected from a plurality of rate-indexed templates stored in the device. Determining if the supraventricular rhythm exhibits rate dependent morphology may also include determining one or more rates at which the rate dependent morphology occurs.
摘要翻译：心脏系统和方法基于确定患者的室上节律表现出速率依赖性，确定了室上性快速性心律失常与室性快速性心律失常之间的区别。一种方法涉及确定患者的室上节律是否表现出速率依赖性形态。如果确定患者的室上节律表现出与速率相关的形态，则可植入装置基于从存储在装置中的多个速率索引模板中选择的一个或多个模板来分类检测到的快速性心律失常发作。确定室性心律显示出速率依赖性形态还可以包括确定发生速率依赖形态的一个或多个速率。

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