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1. 发明授权

US06528994B2 Magnetic field measurement apparatus 有权
公开(公告)号：US06528994B2
公开(公告)日：2003-03-04
申请号：US09941752
申请日：2001-08-30
申请人： Daisuke Suzuki , Atsushi Ninomiya , Tsuyoshi Miyashita , Akihiko Kandori , Keiji Tsukada , Koichi Yokosawa
发明人： Daisuke Suzuki , Atsushi Ninomiya , Tsuyoshi Miyashita , Akihiko Kandori , Keiji Tsukada , Koichi Yokosawa
IPC分类号： G01R3302
CPC分类号： G01R33/24
摘要： A magnetic field measuring apparatus has a magnetic field shielding apparatus including non-magnetic cylindrical members on which high-permeability sheets are located in a state of being partially overlapped with each other. The cylindrical members are located to surround an axis of a first direction concentrically and having a hollow portion, the cylindrical member located on an innermost-side having a first opening at one end of the first direction, a second opening at the other end of the first direction, and a third opening penetrating the cylindrical members in a direction perpendicular to the axis of the first direction. In addition, the magnetic field measuring apparatus has a living-body holder located in an inner-side space of the cylindrical member and a cryostat inserted into the third opening and maintaining SQUID magnetic-flux meters.

2. 发明授权

US06681131B2 Apparatus for measuring bio-magnetic fields 有权
标题翻译：用于测量生物磁场的装置
公开(公告)号：US06681131B2
公开(公告)日：2004-01-20
申请号：US09977213
申请日：2001-10-16
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Daisuke Suzuki , Koichi Yokosawa , Keiji Tsukada
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Daisuke Suzuki , Koichi Yokosawa , Keiji Tsukada
IPC分类号： A61B505
CPC分类号： A61B5/04007 , A61B5/7239 , A61B5/7285
摘要： An apparatus for measuring bio-magnetic fields includes a plurality of magnetometers for detecting magnetic fields generated from a live body; a driving circuit for driving the magnetometers; a computer for collecting output signals of the driving circuit in the form of data representing at least one waveform of the magnetic fields generated from the live body and for performing an arithmetic processing on the data representing the waveform of magnetic fields, a display unit, and at least one signal processing circuit for processing output signals of the driving circuit. The computer further performs an arithmetic processing of first-order differentiation on the waveform of the magnetic fields in a z direction with respect to time in order to create an arrow map and a contour map. The apparatus can also detect mechanical movement which occurs as blood flows in organs and organs move.
摘要翻译：一种用于测量生物磁场的装置包括：用于检测从活体产生的磁场的多个磁力计; 用于驱动磁力计的驱动电路; 用于以表示从活体产生的磁场的至少一个波形的数据形式收集驱动电路的输出信号并且对表示磁场波形的数据执行算术处理的计算机，显示单元和至少一个信号处理电路，用于处理驱动电路的输出信号。计算机进一步对z方向上的磁场波形进行一阶微分的运算处理，以便产生箭头图和轮廓图。该装置还可以检测器官和器官中的血液流动时发生的机械运动。

3. 发明授权

US06665552B2 Gradiometer integrating pickup coils and magnetic field measurement system 有权
公开(公告)号：US06665552B2
公开(公告)日：2003-12-16
申请号：US09940507
申请日：2001-08-29
申请人： Koichi Yokosawa , Daisuke Suzuki , Keiji Tsukada , Tsuyoshi Miyashita , Akihiko Kandori
发明人： Koichi Yokosawa , Daisuke Suzuki , Keiji Tsukada , Tsuyoshi Miyashita , Akihiko Kandori
IPC分类号： A61B505
CPC分类号： G01R33/022 , G01R33/0358
摘要： A gradiometer integrating pickup coils comprises pickup coils 11Xp, 11Xn magnetically connected to a SQUID through associated input coils 2, and pickup coils 11Yp, 11Yn magnetically connected to a SQUID through associated input coils 2, respectively. Two superconducting loops are connected in series to each of the SQUIDs, when viewed from Josephson junctions 5. The input coils 2 form superconducting closed loops together with the pickup coils 11Xp, 11Xn, 11Yp, 11Yn associated therewith. The SQUIDs are respectively connected to form an 8-figured shape as a whole such that currents flow in two superconducting loops of each SQUID in opposite directions to each other, with respect to the application of a uniform field, in order to reduce environmental magnetic field noise.

4. 发明授权

US06745063B2 Biomagnetic field measuring apparatus 有权
标题翻译：生物磁场测量装置
公开(公告)号：US06745063B2
公开(公告)日：2004-06-01
申请号：US09940542
申请日：2001-08-29
申请人： Keiji Tsukada , Tsuyoshi Miyashita , Akihiko Kandori , Daisuke Suzuki , Koichi Yokosawa
发明人： Keiji Tsukada , Tsuyoshi Miyashita , Akihiko Kandori , Daisuke Suzuki , Koichi Yokosawa
IPC分类号： A61B505
CPC分类号： A61B5/04005 , A61B5/4064
摘要： A biomagnetic field measuring apparatus includes a plurality of SQUID magneto-meters for measuring a biomagnetic field generated from a living body, living-body signal measuring devices and for measuring and collecting living-body signals generated periodically, an operation processing device for operation processing the biomagnetic field signal and the living-body signal measured simultaneously as pairs in a plurality of directions, and a display unit for displaying a result of the operation processing. Change in time of excitation can be grasped in detail by using a small number of maps without presumption of a magnetic field source and display of many iso-magnetic field maps.
摘要翻译：生物磁场测量装置包括多个用于测量从生物体产生的生物磁场的SQUID磁电表，生物体信号测量装置，以及用于测量和收集周期性生成的生物体信号的操作处理装置，生物磁场信号和在多个方向上成对测量的生物体信号以及用于显示操作结果的显示单元。可以通过使用少量地图来详细了解激发时间的变化，而不考虑磁场源和显示许多等磁场图。

5. 发明授权

US06815949B2 Apparatus for measuring a magnetic field 失效
标题翻译：磁场测量装置
公开(公告)号：US06815949B2
公开(公告)日：2004-11-09
申请号：US10162748
申请日：2002-06-06
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Koichi Yokosawa , Daisuke Suzuki , Akira Tsukamoto
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Koichi Yokosawa , Daisuke Suzuki , Akira Tsukamoto
IPC分类号： G01R33035
CPC分类号： G01R33/0356 , A61B5/04005 , A61B5/04007 , A61B5/04008 , A61B5/0522
摘要： An apparatus can detect a magnetic field with a high sensitivity using an ordinary-temperature pickup coil even when the pickup coil is arranged outside a cryostat. Specifically, the apparatus for measuring a magnetic field includes a pickup coil for detecting an external magnetic field, a SQUID electrically or magnetically connected to the pickup coil, a cryostat for holding the SQUID at low temperatures, and a driving device for driving the SQUID. The pickup coil is made of a normal-conducting material and is placed at an ordinary temperature outside the cryostat. By arranging outside the cryostat, the pickup coil can be brought close to a subject and can thereby detect a weak magnetic field in the subject with a high sensitivity.

6. 发明授权

US06665553B2 Biomagnetic field measuring apparatus using squid magnetometers for evaluating a rotational property of a current in a subject 有权
标题翻译：使用鱿鱼磁力计的用于评价被检体内的电流的旋转特性的生物磁场测定装置
公开(公告)号：US06665553B2
公开(公告)日：2003-12-16
申请号：US10120406
申请日：2002-04-12
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Masahiro Murakami
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Masahiro Murakami
IPC分类号： A61B505
CPC分类号： A61B5/04009 , A61B5/04007 , A61B2562/02 , A61B2562/046 , G01R33/0354 , G06F19/00
摘要： A biomagnetic field measuring apparatus including: a plurality of magnetometers each employing a superconducting quantum interference device for measuring the magnetic field generated from an organism; a unit for calculating a pseudo-current from a normal component of the magnetic field; a unit for calculating the pseudo-current from the magnetic field obtained from the plurality of magnetometers to integrate the pseudo-current in a fixed direction on the circumference at a fixed distance from each of the associated ones of the sensors; a unit for calculating a maximum value or a minimum value of the integral value obtained by the unit for performing the integral; and a unit for calculating a difference value between the absolute value of the maximum value and the absolute value of the minimum value.
摘要翻译：一种生物磁场测量装置，包括：多个磁力计，每个磁力计采用超导量子干涉装置来测量从生物体产生的磁场; 用于从磁场的正常分量计算伪电流的单元; 用于从所述多个磁力计获得的磁场计算所述伪电流以将固定方向上的所述伪电流与所述相关传感器中的每一个固定距离的圆周上积分的单元; 用于计算由用于执行积分的单元获得的积分值的最大值或最小值的单元; 以及用于计算最大值的绝对值和最小值的绝对值之间的差值的单元。

7. 发明授权

US06462540B1 Magnetic field measuring apparatus which enables external magnetic noise cancellation 有权
标题翻译：能够进行外部磁噪声消除的磁场测量装置
公开(公告)号：US06462540B1
公开(公告)日：2002-10-08
申请号：US09635450
申请日：2000-08-10
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada
IPC分类号： G01R33035
CPC分类号： G01R33/025 , A61B5/0046 , A61B5/04005 , G01R33/0354 , Y10S505/846
摘要： A magnetic field measuring apparatus for precise cancellation of environmental noise includes a plurality of first SQUID gradiometers to detect noise and biomagnetic fields, a plurality of second SQUID gradiometers to detect noise, a driving circuit to drive these gradiometers, and a computer to execute signal processing after collecting the signals detected by these gradiometers. First and second SQUID gradiometers are provided which include first-order gradient pickup coils with the baselines formed by the coils of second gradiometers being shorter than those of first gradiometers. The apparatus cancels noise, from detected biomagnetic signal waveforms, caused by variant noise cancellation rates of the coils of first gradiometers, different baselines of the coils of second gradiometers, and the frequency property of a magnetically shielded room in which the apparatus is installed.
摘要翻译：用于精确地消除环境噪声的磁场测量装置包括多个用于检测噪声和生物磁场的第一SQUID梯度计，用于检测噪声的多个第二SQUID梯度计，用于驱动这些梯度计的驱动电路以及计算机执行信号处理收集这些梯度仪检测到的信号后。提供了第一和第二SQUID梯度计，其包括一级梯度拾取线圈，其中由第二梯度仪的线圈形成的基线比第一梯度计的线圈短。该装置从由第一梯度仪的线圈的不同噪声消除率，第二梯度仪的线圈的不同基线以及安装该装置的磁屏蔽室的频率特性引起的检测到的生物磁信号波形中消除噪声。

8. 发明授权

US07455648B2 Living body inspection apparatus 有权
标题翻译：生活检查仪器
公开(公告)号：US07455648B2
公开(公告)日：2008-11-25
申请号：US10788377
申请日：2004-03-01
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Kenko Uchida , Hideo Kawaguchi , Minoru Sakairi
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Kenko Uchida , Hideo Kawaguchi , Minoru Sakairi
IPC分类号： A61B5/103 , A61B5/05
CPC分类号： A61B5/1101 , A61B5/4082 , A61B5/6824 , A61B5/6826 , A61B5/6828 , A61B5/6838 , A61B5/7239
摘要： A living body inspection apparatus including an oscillation coil which passes an AC current, a detection coil which detects an AC magnetic field generated from the detection coil, an amplification circuit which amplifies a voltage generated by the magnetic field induced by the detection coil, a detecting unit for detecting the output signal of the amplification circuit, a low pass filter to which the output signal of the detecting unit is input, a unit for setting the oscillation coil and detection coil in first and second regions of the living body, a recording unit for recording the output of the low pass filter while the first region and the second region of the living body are moving and a displaying unit for displaying the data recorded in the recording unit or results of analysis of the recorded data.
摘要翻译：一种生物体检查装置，包括通过交流电流的振荡线圈，检测由检测线圈产生的交流磁场的检测线圈，放大电路，放大电路，放大由检测线圈感应出的磁场产生的电压，用于检测放大电路的输出信号的单元，输入检测单元的输出信号的低通滤波器，用于在生物体的第一和第二区域设置振荡线圈和检测线圈的单元，记录单元用于在活体的第一区域和第二区域移动时记录低通滤波器的输出，以及用于显示记录在记录单元中的数据的显示单元或记录数据的分析结果。

9. 发明申请

US20050065422A1 Living body inspection apparatus 有权
标题翻译：生活检查仪器
公开(公告)号：US20050065422A1
公开(公告)日：2005-03-24
申请号：US10788377
申请日：2004-03-01
申请人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Kenko Uchida , Hideo Kawaguchi , Minoru Sakairi
发明人： Akihiko Kandori , Tsuyoshi Miyashita , Keiji Tsukada , Kenko Uchida , Hideo Kawaguchi , Minoru Sakairi
IPC分类号： A61B5/05 , A61B5/11 , A61B5/00
CPC分类号： A61B5/1101 , A61B5/4082 , A61B5/6824 , A61B5/6826 , A61B5/6828 , A61B5/6838 , A61B5/7239
摘要： A living body inspection apparatus including an oscillation coil which passes an AC current, a detection coil which detects an AC magnetic field generated from the detection coil, an amplification circuit which amplifies a voltage generated by the magnetic field induced by the detection coil, a detecting unit for detecting the output signal of the amplification circuit, a low pass filter to which the output signal of the detecting unit is input, a unit for setting the oscillation coil and detection coil in first and second regions of the living body, a recording unit for recording the output of the low pass filter while the first region and the second region of the living body are moving and a displaying unit for displaying the data recorded in the recording unit or results of analysis of the recorded data.
摘要翻译：一种生物体检查装置，包括通过交流电流的振荡线圈，检测由检测线圈产生的交流磁场的检测线圈，放大电路，放大电路，放大由检测线圈感应出的磁场产生的电压，用于检测放大电路的输出信号的单元，输入检测单元的输出信号的低通滤波器，用于在生物体的第一和第二区域设置振荡线圈和检测线圈的单元;记录单元用于在活体的第一区域和第二区域移动时记录低通滤波器的输出，以及用于显示记录在记录单元中的数据的显示单元或记录数据的分析结果。

10. 发明授权

US06609019B1 Physiological magnetic field measuring instrument for measuring magnetic field at plural positions of living body 有权
标题翻译：生物磁场测量仪，用于测量活体多个位置的磁场
公开(公告)号：US06609019B1
公开(公告)日：2003-08-19
申请号：US09493798
申请日：2000-01-28
申请人： Kenji Teshigawara , Hiroyuki Suzuki , Keiji Tsukada , Kazuhisa Machida , Akihiko Kandori , Tsuyoshi Miyashita , Hitoshi Sasabuchi
发明人： Kenji Teshigawara , Hiroyuki Suzuki , Keiji Tsukada , Kazuhisa Machida , Akihiko Kandori , Tsuyoshi Miyashita , Hitoshi Sasabuchi
IPC分类号： A61B505
CPC分类号： A61B5/04007 , A61B5/0402 , A61B5/742
摘要： The present invention, in the physiological magnetic field measuring instrument, recognizes characteristic waveforms (for example, heart beats) repeatedly appearing by physiological activity from measured signal waveforms, registers one of measured heart beats as a reference waveform, evaluates the difference degree of each measured heart beat data from the reference waveform, and executes the averaging process using only waveforms whose difference degrees are less than the allowable value. The present invention registers waveforms whose difference degrees are more than the allowable value as abnormal data and puts them into the display enabled state. Discrimination information is as signed to measurement conditions necessary for measuring the physiological magnetic field and data analysis conditions and when the discrimination information is designated for measurement, the measurement conditions and analysis conditions can be read. By doing this, the physiological magnetic field measuring instrument independently selects good or defective data automatically, and a reliable automatic averaging process can be obtained, and the data processing and operation can be simplified.
摘要翻译：本发明在生理磁场测量仪器中，从测量信号波形中识别由生理活动重复出现的特征波形（例如，心跳），将测量的心跳中的一个记录为参考波形，评估每个测量的差异程度从参考波形心跳数据，并且仅使用差值小于允许值的波形执行平均处理。本发明将差异度大于容许值的波形记录为异常数据，并将其置于显示使能状态。鉴别信息符合测量生理磁场和数据分析条件所需的测量条件，并且当识别信息被指定用于测量时，可以读取测量条件和分析条件。通过这样做，生理磁场测量仪器自动选择好的或有缺陷的数据，可以获得可靠的自动平均过程，可以简化数据处理和操作。

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