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1. 发明申请

WO2012150269A1 PROBIOTIC BACTERIA FOR THE TOPICAL TREATMENT OF SKIN DISORDERS 审中-公开
标题翻译：用于皮肤病症局部治疗的生物细菌
公开(公告)号：WO2012150269A1
公开(公告)日：2012-11-08
申请号：PCT/EP2012/058047
申请日：2012-05-02
申请人： DUPONT NUTRITION BIOSCIENCES APS , PUTAALA, Heli , OUWEHAND, Arthur , TIIHONEN, Kirsti , RAUTONEN, Nina
发明人： PUTAALA, Heli , OUWEHAND, Arthur , TIIHONEN, Kirsti , RAUTONEN, Nina
IPC分类号： A61K31/205 , A61K35/74 , A61P17/06 , A61P17/16
CPC分类号： A61K35/741 , A61K31/205 , A61K35/744 , A61K35/745 , A61K35/747
摘要： The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with Tight Junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.
摘要翻译：本发明涉及用于治疗与紧结功能相关的病症的益生菌和/或益生菌的细胞裂解液的益生菌和/或可溶性代谢物，其特征在于益生菌，可溶性将益生菌和/或益生菌的细胞裂解液的代谢物配制成局部给药。

2. 发明申请

WO2007085970A2 USE 审中-公开
标题翻译：使用
公开(公告)号：WO2007085970A2
公开(公告)日：2007-08-02
申请号：PCT/IB2007/001186
申请日：2007-01-26
申请人： DANISCO A/S , RAUTONEN, Nina , PUTAALA, Heli , OUWEHAND, Arthur , TIIHONEN, Kirsti
发明人： RAUTONEN, Nina , PUTAALA, Heli , OUWEHAND, Arthur , TIIHONEN, Kirsti
IPC分类号： A61K35/745 , A61K35/747
CPC分类号： A61K35/747 , A23K10/18 , A23K50/40 , A23K50/75 , A23L33/135 , A23L33/30 , A61K35/745
摘要： Use of at least one strain of a microorganism and/or a metabolite thereof in the manufacture of a support for administration to a subject for modulating satiety signalling, wherein the support is a pharmaceutically acceptable support or a food product. Suitably, the at least one strain of a microorganism and/or a metabolite thereof may be administered to the subject for the treatment and/or prevention of excess weight and/or a disease caused by excess weight. Likewise, the at least one strain of a microorganism and/or a metabolite thereof is administered to the subject for the treatment and/or prevention of obesity and/or a disease caused by obesity. Preferably, the microorganism is a probiotic microorganism. Suitably the microorganism may be a lactic acid bacterium. Li one embodiment the microorganism is a strain of Lactobacillus spp. and/or Bifidobacterium spp., for example a strain of Lactobacillus acidophilus, L. curvatus, L. salivarius and/or B. lactis.
摘要翻译：至少一种微生物菌株和/或其代谢物在制备用于施用受试者以调节饱腹感信号的载体中的用途，其中所述载体是药学上可接受的载体或食品。适当地，将微生物和/或其代谢物的至少一种菌株施用于受试者以治疗和/或预防超重和/或由超重引起的疾病。同样地，向受试者施用至少一种微生物和/或其代谢物，用于治疗和/或预防肥胖症和/或由肥胖引起的疾病。优选地，微生物是益生菌微生物。适当地，微生物可以是乳酸菌。李一个实例是微生物是一种乳杆菌属菌株。和/或双歧杆菌属，例如嗜酸乳杆菌，弯曲曲霉，唾液乳杆菌和/或乳酸乳杆菌的菌株。

3. 发明申请

WO2011013106A1 LACTIC ACID BACTERIA AND BIFIDOBACTERIA FOR TREATING ENDOTOXEMIA 审中-公开
标题翻译：用于治疗内毒素的乳酸菌和双歧杆菌
公开(公告)号：WO2011013106A1
公开(公告)日：2011-02-03
申请号：PCT/IB2010/053482
申请日：2010-07-30
申请人： DANISCO A/S , BURCELIN, Rémy , CARCANO, Didier , DESREUMAUX, Pierre , LAHTINEN, Sampo , RAUTONEN, Nina , PUTAALA, Heli , TIIHONEN, Kirsti , BARRANGOU, Rodolphe
发明人： BURCELIN, Rémy , CARCANO, Didier , DESREUMAUX, Pierre , LAHTINEN, Sampo , RAUTONEN, Nina , PUTAALA, Heli , TIIHONEN, Kirsti , BARRANGOU, Rodolphe
IPC分类号： A61K35/74 , A61P5/50 , A61P29/00
CPC分类号： A61K35/747 , A61K35/74 , A61K35/745 , A61K2035/115 , A61P5/50 , A61P29/00 , A61K2300/00
摘要： The invention relates to use of a bacterium selected from a lactic acid bacterium, a Bifidobacterium or a mixture of any thereof for treating metabolic endotoxemia, inhibiting bacterial translocation and regulating lipid absorption in a mammal.
摘要翻译：本发明涉及选自乳酸菌，双歧杆菌或其混合物中的细菌用于治疗代谢性内毒素血症，抑制细菌易位并调节哺乳动物脂质吸收的用途。

4. 发明申请

WO2008155536A1 ANIMAL FEED PRODUCT 审中-公开
标题翻译：动物饲料产品
公开(公告)号：WO2008155536A1
公开(公告)日：2008-12-24
申请号：PCT/GB2008/002070
申请日：2008-06-17
申请人： DANISCO A/S , SCHULZE, Hagen, Klaus , TAYLOR, Robert, Barry , KETTUNEN, Hannele , OUWEHAND, Arthur, C. , SAARINEN, Markku , RAUTONEN, Nina , PEURANEN, Seppo , LINO BENTO, Maria, Helena , TIIHONEN, Kirsti, Kaarina
发明人： SCHULZE, Hagen, Klaus , TAYLOR, Robert, Barry , KETTUNEN, Hannele , OUWEHAND, Arthur, C. , SAARINEN, Markku , RAUTONEN, Nina , PEURANEN, Seppo , LINO BENTO, Maria, Helena , TIIHONEN, Kirsti, Kaarina
IPC分类号： A23K1/18 , A23K1/16 , A23K1/165
CPC分类号： A23K50/75 , A23K20/10 , A23K20/111 , A23K20/189 , A23K40/10
摘要： The present invention provides an animal feed additive obtainable by: (a) mixing water, an emulsion stabilizer and a physiologically acceptable carrier to form a gum solution; (b) adding to the gum solution, separately or combined, an oil blend comprising: (i) cinnamaldehyde and (ii) a compound selected from the group consisting of citral, eugenol, limonene, thymol, vanillin and combinations thereof; (c) mixing the gum solution and the oil blend and homogenizing this mixture under pressure to form an emulsion; and (d) spray drying and/or agglomerating the mixture to form a powder.
摘要翻译：本发明提供一种动物饲料添加剂，其可通过以下方法获得：（a）将水，乳剂稳定剂和生理学上可接受的载体混合以形成胶溶液; （b）单独或组合的添加到胶溶液中的油混合物，其包含：（i）肉桂醛和（ii）选自柠檬醛，丁子香酚，柠檬烯，百里酚，香草醛及其组合的化合物; （c）将胶溶液和油混合物混合并在压力下均化该混合物以形成乳液; 和（d）将混合物喷雾干燥和/或附聚以形成粉末。

5. 发明申请

WO2008122892A2 PROBIOTICS FOR USE IN REDUCING EOSINOPHILIA AND RESPIRATORY ALLERGIES 审中-公开
标题翻译：用于减少EOSINOPHILIA和呼吸过敏的益生菌
公开(公告)号：WO2008122892A2
公开(公告)日：2008-10-16
申请号：PCT/IB2008/001503
申请日：2008-03-26
申请人： DANISCO A/S , ISOLAURI, Erika , OUWEHAND, Arthur , RAUTONEN, Nina , SALMINEN, Seppo, Jaakko
发明人： ISOLAURI, Erika , OUWEHAND, Arthur , RAUTONEN, Nina , SALMINEN, Seppo, Jaakko
IPC分类号： A61K35/74 , A23L1/30 , A61P37/02
CPC分类号： A61K35/747 , A23L33/135 , A23V2002/00 , A23Y2220/03 , A23Y2300/49 , A61K35/745 , A61K2035/115 , A23V2200/304 , A23V2200/3204
摘要： The present invention provides probiotic compositions suitable for reducing the incidence and duration of nasal eosinophilia and other parameters associated with birch pollen allergy. In some embodiments, the present invention provides methods and/or compositions suitable for reducing nasal and/or respiratory allergy symptoms.
摘要翻译：本发明提供了适合于降低鼻嗜酸粒细胞增多症的发病率和持续时间以及与桦树花粉过敏有关的其他参数的益生菌组合物。在一些实施方案中，本发明提供了适合于减轻鼻和/或呼吸道过敏症状的方法和/或组合物。

6. 发明申请

WO2008071930A1 COMPOSITION 审中-公开
标题翻译：组成
公开(公告)号：WO2008071930A1
公开(公告)日：2008-06-19
申请号：PCT/GB2007/004714
申请日：2007-12-10
申请人： DANISCO A/S , RAUTONEN, Nina , OUWEHAND, Arthur , STOWELL, Julian , MAKELAINEN, Henna
发明人： RAUTONEN, Nina , OUWEHAND, Arthur , STOWELL, Julian , MAKELAINEN, Henna
IPC分类号： A23C9/123 , A23C9/13 , A23C9/152 , A23L1/00 , A23L1/29 , A23L1/30 , A23L2/39
CPC分类号： A23C9/1234 , A23C9/1307 , A23C9/152 , A23L2/39 , A23L33/135 , A23L33/21 , A23L33/40 , A23V2002/00 , A23Y2300/00 , A23V2250/28 , A23V2200/08
摘要： The present invention provides a composition comprising: (a) one or more live Bifidobacterium lactis strains; and (b) a saccharide component; wherein the saccharide component comprises xylo-oligosaccharides with a degree of polymerisation of from 2 to 100.
摘要翻译：本发明提供一种组合物，其包含：（a）一种或多种活双歧杆菌活菌; 和（b）糖组分; 其中所述糖组分包含聚合度为2至100的低聚木糖。

7. 发明授权

EP2704704B1 PROBIOTIC BACTERIA FOR THE TOPICAL TREATMENT OF SKIN DISORDERS 有权转让
公开(公告)号：EP2704704B1
公开(公告)日：2018-09-26
申请号：EP12730161.2
申请日：2012-05-02
申请人： DuPont Nutrition Biosciences ApS
发明人： PUTAALA, Heli , OUWEHAND, Arthur , TIIHONEN, Kirsti , RAUTONEN, Nina
IPC分类号： A61K35/74 , A61K35/747 , A61K35/745 , A61K35/744 , A61P17/00 , A61P17/18 , A61P37/00
CPC分类号： A61K35/741 , A61K31/205 , A61K35/744 , A61K35/745 , A61K35/747
摘要： The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with Tight Junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.

8. 发明授权

EP1465505B1 STIMULATION OF THE IMMUNE SYSTEM WITH POLYDEXTROSE 失效转让
标题翻译：起搏POLYDEXTROSE免疫系统
公开(公告)号：EP1465505B1
公开(公告)日：2015-11-18
申请号：EP02799071.2
申请日：2002-12-23
申请人： DuPont Nutrition Biosciences ApS
发明人： RAUTONEN, Nina , APAJALAHTI, Juha , TIIHONEN, Kirsti
IPC分类号： A23L1/308 , A23K1/16 , A61P37/04 , A61P1/00
CPC分类号： A23L33/26

9. 发明授权

EP2459203B1 LACTIC ACID BACTERIA AND BIFIDOBACTERIA FOR TREATING ENDOTOXEMIA 有权转让
公开(公告)号：EP2459203B1
公开(公告)日：2018-10-31
申请号：EP10747076.7
申请日：2010-07-30
申请人： DuPont Nutrition Biosciences ApS
发明人： BURCELIN, Rémy , CARCANO, Didier , DESREUMAUX, Pierre , LAHTINEN, Sampo , RAUTONEN, Nina , PUTAALA, Heli , TIIHONEN, Kirsti , BARRANGOU, Rodolphe
IPC分类号： A61P29/00 , A61K35/745 , A61K35/747 , A61P5/50
CPC分类号： A61K35/747 , A61K35/74 , A61K35/745 , A61K2035/115 , A61P5/50 , A61P29/00 , A61K2300/00
摘要： The invention relates to use of a bacterium selected from a lactic acid bacterium, a Bifidobacterium or a mixture of any thereof for treating metabolic endotoxemia, inhibiting bacterial translocation and regulating lipid absorption in a mammal.

10. 发明授权

EP2139502B1 LACTOBACILLUS AND BIFIDOBACTERIUM AGAINST BIRCH ALLERGY 有权
标题翻译：乳酸菌和双歧杆菌反对桦树过敏症
公开(公告)号：EP2139502B1
公开(公告)日：2014-06-18
申请号：EP08776272.0
申请日：2008-03-26
申请人： DuPont Nutrition Biosciences ApS
发明人： ISOLAURI, Erika , OUWEHAND, Arthur , RAUTONEN, Nina , SALMINEN, Seppo, Jaakko
IPC分类号： A61K35/74 , A61P37/08
CPC分类号： A61K35/747 , A23L33/135 , A23V2002/00 , A23Y2220/03 , A23Y2300/49 , A61K35/745 , A61K2035/115 , A23V2200/304 , A23V2200/3204
摘要： The present invention provides probiotic compositions suitable for reducing the incidence and duration of nasal eosinophilia and other parameters associated with birch pollen allergy. In some embodiments, the present invention provides methods and/or compositions suitable for reducing nasal and/or respiratory allergy symptoms. Suitably, such compositions may comprise L. acidophilus, B. lactis or both.

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