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1. 发明申请

WO2010046297A1 IMPROVING PEPTIDE AVAILABILTY 审中-公开
标题翻译：改善抗癌药物
公开(公告)号：WO2010046297A1
公开(公告)日：2010-04-29
申请号：PCT/EP2009/063467
申请日：2009-10-15
申请人： DSM IP ASSETS B.V. , KIES, Arie, Karst , PIJL, VAN DER, Pieter Cornelis
发明人： KIES, Arie, Karst , PIJL, VAN DER, Pieter Cornelis
IPC分类号： A23L1/305 , A61K38/01 , A61K38/06 , A61K38/16 , A61P9/12
CPC分类号： A23K50/40 , A23K20/147 , A23L33/18 , A23L33/185 , A23L33/19 , A23L33/195 , A61K38/01 , A61K38/011 , A61K38/018 , A61K38/06
摘要： The present invention provides a process for producing a composition which is preferably a food, food intermediate, dietary supplement, feed or pet food, which comprises mixing together a peptide mixture, comprising a bioactive peptide, and a protein source having a protein quality (expressed as PER) of 2.4 or lower. The composition of the invention can be used to improve the bioavailability of bioactive peptides or used as a food, food intermediate, nutraceutical, dietary supplement, feed, or pet food.
摘要翻译：本发明提供一种制备组合物的方法，其优选为食品，食品中间体，膳食补充剂，饲料或宠物食品，其包括将包含生物活性肽的肽混合物和具有蛋白质质量的蛋白质源（表达作为PER）为2.4或更低。本发明的组合物可用于改善生物活性肽的生物利用度或用作食品，食品中间体，营养保健品，膳食补充剂，饲料或宠物食品。

2. 发明申请

WO2003009701A1 ANIMAL FEED WITH LOW PUFA CONCENTRATION 审中-公开
标题翻译：具有低PUFA浓度的动物饲料
公开(公告)号：WO2003009701A1
公开(公告)日：2003-02-06
申请号：PCT/EP2002/008159
申请日：2002-07-22
申请人： DSM N.V. , KIES, Arie, Karst
发明人： KIES, Arie, Karst
IPC分类号： A23K1/16
CPC分类号： C12Y101/03004 , A23K20/10 , A23K20/158 , A23K20/189 , A23K50/70 , A23V2002/00 , A61K31/20 , C12Y113/11012 , A23V2200/10 , A23V2250/1862 , A23V2250/1882
摘要： The use of low concentrations of (a) PUFA (s) in an animal feed for monogastric and/or non-ruminant animals is disclosed to improve growth and feed conversion ratio. The concentration can be much lower than expected from the art, namely from 0.1 to 0.0001 g/kg feed, and yet still be effective. This may enable farmers to use lower concentrations of PUFA (s) in feed and hence reduce the cost of the feed. The feed may also have one or more antimicrobial enzymes present.
摘要翻译：公开了在单胃和/或非反刍动物的动物饲料中使用低浓度的（a）PUFA以改善生长和饲料转化率。浓度可以远远低于本领域的预期值，即0.1至0.0001g / kg饲料，仍然有效。这可能使农民在饲料中使用较低浓度的PUFA，从而降低饲料的成本。饲料还可以具有一种或多种存在的抗微生物酶。

3. 发明申请

WO2003034816A1 PUFAS IN EGGS 审中-公开
标题翻译：蜂蜜中的PUFAS
公开(公告)号：WO2003034816A1
公开(公告)日：2003-05-01
申请号：PCT/EP2002/011749
申请日：2002-10-21
申请人： DSM N.V. , KIES, Arie, Karst , SIMONS, Petrus, Cornelis, Maria , VAN DOESUM, Johannes, Henricus
发明人： KIES, Arie, Karst , SIMONS, Petrus, Cornelis, Maria , VAN DOESUM, Johannes, Henricus
IPC分类号： A01K45/00
CPC分类号： A01K45/007
摘要： A process for improving the survival rate (post-hatching) or hatching rate of chicks from an egg is disclosed, where the polyunsaturated fatty acid (PUFA) content of the egg is increased. Such an increase can also improve growth, feed conversion ratio or the immunological status of the hatched chicks. Improvements in these parameters have been found even when increasing the PUFA content of the egg by as little as 0.01 %. The PUFA is transported across the shell of the egg, by manual injection, and the PUFA can be injected into the egg yolk, into the egg white, or both. Injection can be within 24 hours of the egg being laid. The invention therefore also provides novel eggs, where at least 10% of the arachidonic acid (ARA) inside the eggs is in triglyceride form. The invention also provides eggs that contain one or more PUFAs or lipids in the egg white, or where the egg (or yolk) has at least 120 mg of a PUFA such as ARA. These eggs may be intact, with a shell, or may be without the shell (and therefore in a raw or cooked form). Such eggs can be included into foodstuffs, such as for humans.
摘要翻译：公开了一种提高鸡蛋生存率（孵化后）或雏鸡孵化率的方法，其中鸡蛋的多不饱和脂肪酸（PUFA）含量增加。这样的增加也可以改善孵化雏鸡的生长，饲料转化率或免疫状态。即使将蛋黄的PUFA含量提高到0.01％，也已经发现了这些参数的改进。 PUFA通过手动注射运输穿过鸡蛋壳，PUFA可以注入蛋黄，蛋白或两者。注射可以在鸡蛋放置的24小时内。因此，本发明还提供了新颖的蛋，其中蛋中至少10％的花生四烯酸（ARA）是甘油三酯形式。本发明还提供在蛋清中含有一种或多种PUFA或脂质的蛋，或者蛋（或蛋黄）具有至少120mg的PUFA如ARA的蛋。这些蛋可以是完整的，有壳，或者可以没有壳（因此是生的或熟的形式）。这样的蛋可以包括在食物中，例如人类。

4. 发明申请

WO2003009700A1 COCCIDIOSTATS 审中-公开
标题翻译：抗球虫药
公开(公告)号：WO2003009700A1
公开(公告)日：2003-02-06
申请号：PCT/EP2002/008158
申请日：2002-07-22
申请人： DSM N.V. , VAN DOESUM, Johannes, Henricus , KIES, Arie, Karst
发明人： VAN DOESUM, Johannes, Henricus , KIES, Arie, Karst
IPC分类号： A23K1/16
CPC分类号： C12Y101/03004 , A23K20/10 , A23K20/158 , A23K20/189 , A23K50/70 , A23V2002/00 , A61K31/20 , C12Y113/11012 , A23V2200/10 , A23V2250/1862 , A23V2250/1882
摘要： The use of a polyunsaturated fatty acid (PUFA) as, or in the preparation of, a coccidiostat is disclosed. PUFAs have been discovered to have coccidiostatic activity, and can therefore be used in the treatment or prophylaxis of coccidiosis. They can be employed in both veterinary and pharmaceutical compositions to treat both humans and animals. The PUFA may also be included in animal feed. The PUFA is active against single cell coccidia organisms, especially of the subgroup Eimeriorina, in particular in E. acervulina, E. maxima or E. tenella .
摘要翻译：公开了使用多不饱和脂肪酸（PUFA）或制备球虫抑制剂。已经发现PUFA具有抗球虫活性，因此可用于治疗或预防球虫病。它们可以用于兽医和药物组合物中以治疗人和动物。 PUFA也可以包括在动物饲料中。 PUFA对单细胞球虫生物体尤其是亚麻组，尤其是大肠埃希氏菌（E.acervulina），大肠埃希氏菌（E.gala）或大肠杆菌（E. tenella）有活性。

5. 发明公开

EP2346359A1 IMPROVING PEPTIDE AVAILABILTY 审中-公开
标题翻译：改进的可用性肽
公开(公告)号：EP2346359A1
公开(公告)日：2011-07-27
申请号：EP09744360.0
申请日：2009-10-15
申请人： DSM IP Assets B.V.
发明人： KIES, Arie, Karst , PIJL, VAN DER, Pieter Cornelis
IPC分类号： A23L1/305 , A61K38/01 , A61K38/06 , A61K38/16 , A61P9/12
CPC分类号： A23K50/40 , A23K20/147 , A23L33/18 , A23L33/185 , A23L33/19 , A23L33/195 , A61K38/01 , A61K38/011 , A61K38/018 , A61K38/06
摘要： The present invention provides a process for producing a composition which is preferably a food, food intermediate, dietary supplement, feed or pet food, which comprises mixing together a peptide mixture, comprising a bioactive peptide, and a protein source having a protein quality (expressed as PER) of 2.4 or lower. The composition of the invention can be used to improve the bioavailability of bioactive peptides or used as a food, food intermediate, nutraceutical, dietary supplement, feed, or pet food.

6. 发明公开

EP1416809A1 ANIMAL FEED WITH LOW PUFA CONCENTRATION 审中-公开
标题翻译：低浓度的多不饱和脂肪酸动物饲料
公开(公告)号：EP1416809A1
公开(公告)日：2004-05-12
申请号：EP02790184.2
申请日：2002-07-22
申请人： DSM IP Assets B.V.
发明人： KIES, Arie, Karst
IPC分类号： A23K1/16 , A23K1/165 , A01N63/04
CPC分类号： C12Y101/03004 , A23K20/10 , A23K20/158 , A23K20/189 , A23K50/70 , A23V2002/00 , A61K31/20 , C12Y113/11012 , A23V2200/10 , A23V2250/1862 , A23V2250/1882
摘要： The use of low concentrations of (a) PUFA (s) in an animal feed for monogastric and/or non-ruminant animals is disclosed to improve growth and feed conversion ratio. The concentration can be much lower than expected from the art, namely from 0.1 to 0.0001 g/kg feed, and yet still be effective. This may enable farmers to use lower concentrations of PUFA (s) in feed and hence reduce the cost of the feed. The feed may also have one or more antimicrobial enzymes present.

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