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1. 发明申请

WO2004067750A3 XENORHABDUS TC PROTEINS AND GENES FOR PEST CONTROL 审中-公开
标题翻译： XENORHABDUS TC蛋白和基因用于虫害控制
公开(公告)号：WO2004067750A3
公开(公告)日：2004-10-07
申请号：PCT/US2004000314
申请日：2004-01-07
申请人： DOW AGROSCIENCES LLC , BINTRIM SCOTT B , MITCHELL JON C , LARRINUA IGNACIO M , APEL-BIRKHOLD PATRICIA C , GREEN SUSAN B , SCHAFER BARRY W , BEVAN SCOTT A , YOUNG SCOTT A , GUO LINING
发明人： BINTRIM SCOTT B , MITCHELL JON C , LARRINUA IGNACIO M , APEL-BIRKHOLD PATRICIA C , GREEN SUSAN B , SCHAFER BARRY W , BEVAN SCOTT A , YOUNG SCOTT A , GUO LINING
IPC分类号： C12N5/02 , C12N15/82 , C07K14/24
CPC分类号： C12N15/8286 , Y02A40/162
摘要： The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus strain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. This exochitinase can be used to control insects using methods known in the art.
摘要翻译：本发明涉及新的Xenorhabdus毒素复合物（TC）蛋白质和编码这些蛋白质的基因。更具体地说，本发明涉及可从Xenorhabdus菌株Xwi获得的TC基因和蛋白质。本发明还提供可从Xwi菌株获得的外切壳多糖酶。该外切壳多糖酶可用于使用本领域已知的方法来控制昆虫。

2. 发明申请

WO2006094161A3 NEW SOURCES FOR, AND TYPES OF, INSECTICIDALLY ACTIVE PROTEINS, AND POLYNUCLEOTIDES THAT ENCODE THE PROTEINS 审中-公开
标题翻译：新的来源和类型的杀虫活性蛋白质和编码蛋白质的多核苷酸
公开(公告)号：WO2006094161A3
公开(公告)日：2007-03-08
申请号：PCT/US2006007524
申请日：2006-03-02
申请人： DOW AGROSCIENCES LLC , LARRINUA IGNACIO M , MERLO DONALD J , WOOSLEY AARON TODD , HEY TIMOTHY D , MEADE THOMAS , BURTON STEPHANIE LOVE
发明人： LARRINUA IGNACIO M , MERLO DONALD J , WOOSLEY AARON TODD , HEY TIMOTHY D , MEADE THOMAS , BURTON STEPHANIE LOVE
IPC分类号： A01N65/00 , C12N15/82 , C07K14/195 , C07K14/37
CPC分类号： C07K14/195 , A01N63/00 , A01N63/04 , C07K14/20 , C07K14/21 , C07K14/37 , C07K16/14 , C07K2319/00 , Y10S530/858
摘要： The subject invention provides exciting new sources for surprising, new types of toxin complex ("TC") proteins. The subject invention includes these new classes and types of TC proteins. The subject invention also includes polynucleotides that encode the subject proteins. The subject invention further provides vectors and cells comprising these polynucleotides. The subject invention also provides novel methods of controlling insects. The subject invention relates in part to the surprising discovery that new types of TC proteins can be obtained from a widely diverse phylogenetic spectrum of organisms including, most notably and surprisingly, eukaryotic fungus.
摘要翻译：本发明为令人惊奇的新型毒素复合物（“TC”）蛋白质提供令人兴奋的新来源。本发明包括这些新类型和TC蛋白。本发明还包括编码受试蛋白的多核苷酸。本发明进一步提供了包含这些多核苷酸的载体和细胞。本发明还提供了控制昆虫的新方法。本发明部分地涉及令人惊奇的发现，即可以从广泛多样的生物学系统发育谱获得新型TC蛋白质，包括最引人注目和令人惊讶的真核真菌。

3. 发明申请

WO2007149715A3 NOVEL DNA SEQUENCES, VECTORS AND PROTEINS OF AVIAN INFLUENZA HEMAGGLUTININ 审中-公开
标题翻译： AVIAN INFLUENZA HEMAGGLUTININ的新型DNA序列，载体和蛋白
公开(公告)号：WO2007149715A3
公开(公告)日：2008-07-24
申请号：PCT/US2007070755
申请日：2007-06-08
申请人： DOW AGROSCIENCES LLC , HENRY MATTHEW , LARRINUA IGNACIO M , RUSSELL SEAN M
发明人： HENRY MATTHEW , LARRINUA IGNACIO M , RUSSELL SEAN M
IPC分类号： A61K39/12 , A61K39/145
CPC分类号： A61K39/145 , A61K39/12 , A61K2039/517 , A61K2039/545 , C07K14/005 , C07K2319/00 , C12N15/8258 , C12N2760/16122 , C12N2760/16134
摘要： The subject invention provides novel amino acid sequences (including a consensus sequence) of the Avian Influenza A virus hemagglutinin protein. These newly constructed genes are designed to provide a broader spectrum of activity across the serotype family thus providing a basis for a vaccine that has broad heterologous disease protection. The novel genes have been further improved by the addition of strategic glycosylation sites into the amino acids sequences that they encode. These genes can also, optionally, be codon optimized for plant expression, inserted into the appropriate vector and cloned into plants for expression. Polypeptides produced by recombinant host cells or transgenic plants can also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals. Additionally, transgenic plant material may also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals.
摘要翻译：本发明提供禽流感A病毒血凝素蛋白的新型氨基酸序列（包括共有序列）。这些新构建的基因被设计为提供跨血清型家族的更广泛的活性范围，从而为具有广泛异源疾病保护的疫苗提供基础。通过在其编码的氨基酸序列中加入战略糖基化位点，进一步改善了这些新基因。这些基因也可任选地优化用于植物表达的密码子，插入合适的载体中并克隆到植物中用于表达。通过重组宿主细胞或转基因植物产生的多肽也可以用作疫苗来源，用于制定用于控制易感个体中的流感的疫苗。另外，转基因植物材料也可以用作疫苗的来源，用于制定用于控制易感个体中的流感的疫苗。

4. 发明专利

CA2654178A1 NOVEL DNA SEQUENCES, VECTORS AND PROTEINS OF AVIAN INFLUENZAHEMAGGLUTININ 未知
公开(公告)号：CA2654178A1
公开(公告)日：2007-12-27
申请号：CA2654178
申请日：2007-06-08
申请人： DOW AGROSCIENCES LLC
发明人： RUSSELL SEAN M , LARRINUA IGNACIO M , HENRY MATTHEW
IPC分类号： A61K39/12 , A61K39/145
摘要： The subject invention provides novel amino acid sequences (including a co nsensus sequence) of the Avian Influenza A virus hemagglutinin protein. Thes e newly constructed genes are designed to provide a broader spectrum of acti vity across the serotype family thus providing a basis for a vaccine that ha s broad heterologous disease protection. The novel genes have been further i mproved by the addition of strategic glycosylation sites into the amino acid s sequences that they encode. These genes can also, optionally, be codon opt imized for plant expression, inserted into the appropriate vector and cloned into plants for expression. Polypeptides produced by recombinant host cells or transgenic plants can also be used as source of antigen for the formulat ion of vaccines for the control of influenza in susceptible individuals. Add itionally, transgenic plant material may also be used as source of antigen f or the formulation of vaccines for the control of influenza in susceptible i ndividuals.

5. 发明专利

ZA200808845B Novel DNA sequences, vectors and proteins of Avian Influenza hemagglutinin 未知
公开(公告)号：ZA200808845B
公开(公告)日：2009-10-28
申请号：ZA200808845
申请日：2008-10-16
申请人： DOW AGROSCIENCES LLC
发明人： MATTHEW HENRY , LARRINUA IGNACIO M , RUSSELL SEAN M
IPC分类号： A61K20100101
摘要： The subject invention provides novel amino acid sequences (including a consensus sequence) of the Avian Influenza A virus hemagglutinin protein. These newly constructed genes are designed to provide a broader spectrum of activity across the serotype family thus providing a basis for a vaccine that has broad heterologous disease protection. The novel genes have been further improved by the addition of strategic glycosylation sites into the amino acids sequences that they encode. These genes can also, optionally, be codon optimized for plant expression, inserted into the appropriate vector and cloned into plants for expression. Polypeptides produced by recombinant host cells or transgenic plants can also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals. Additionally, transgenic plant material may also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals.

6. 发明专利

BR102013032916A2 polinucleotídeo recombinante, vetor de transformação, molécula de ácido ribonucleico, célula, bem como métodos para controlar população ou infestação de praga oleóptera, para melhorar o rendimento de cultura de milho e para produzir célula de planta ou planta transgênica 未知
公开(公告)号：BR102013032916A2
公开(公告)日：2015-12-29
申请号：BR102013032916
申请日：2013-12-19
申请人： DOW AGROSCIENCES LLC
发明人： WOOSLEY AARON T , GENG CHAOXIAN , LI HUARONG , LARRINUA IGNACIO M , NARVA KENNETH , HENRY MATTHEW J , OLSON MONICA B , RANGASAMY MURUGESAN , ELANGO NAVIN
IPC分类号： A01H1/00 , A01H5/00 , C12N15/12 , C12N15/82
摘要： polinucleotídeo recombinante, vetor de transformação, molécula de ácido ribonucleico, célula, bem como métodos para controlar população ou infestação de praga oleóptera, para melhorar o rendimento de cultura de milho e para produzir célula de planta ou planta transgênica. a presente invenção refere-se a moléculas de ácido nucleico e a métodos de uso das mesmas para o controle de pragas coleópteras através da inibição mediada por rna de interferência de sequências codificadoras ou de sequências não codificadoras alvo transcritas em pragas coleópteras. a invenção também se refere a métodos para fazer plantas transgênicas que expressam moléculas de ácido nucleico úteis para o controle de pragas coleópteras, e a células vegetais e plantas obtidas dessa maneira.

7. 发明专利

AU2007261196A1 Novel dna sequences, vectors and proteins of avian influenza hemagglutinin 未知
公开(公告)号：AU2007261196A1
公开(公告)日：2007-12-27
申请号：AU2007261196
申请日：2007-06-08
申请人： DOW AGROSCIENCES LLC
发明人： RUSSELL SEAN M , LARRINUA IGNACIO M , HENRY MATTHEW
IPC分类号： A61K39/12 , A61K39/145
摘要： The subject invention provides novel amino acid sequences (including a consensus sequence) of the Avian Influenza A virus hemagglutinin protein. These newly constructed genes are designed to provide a broader spectrum of activity across the serotype family thus providing a basis for a vaccine that has broad heterologous disease protection. The novel genes have been further improved by the addition of strategic glycosylation sites into the amino acids sequences that they encode. These genes can also, optionally, be codon optimized for plant expression, inserted into the appropriate vector and cloned into plants for expression. Polypeptides produced by recombinant host cells or transgenic plants can also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals. Additionally, transgenic plant material may also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals.

8. 发明专利

CA2608859A1 NEW SOURCES FOR, AND TYPES OF, INSECTICIDALLY ACTIVE PROTEINS, AND POLYNUCLEOTIDES THAT ENCODE THE PROTEINS 未知
公开(公告)号：CA2608859A1
公开(公告)日：2006-09-08
申请号：CA2608859
申请日：2006-03-02
申请人： DOW AGROSCIENCES LLC
发明人： MERLO DONALD J , LARRINUA IGNACIO M , WOOSLEY AARON TODD , HEY TIMOTHY D , MEADE THOMAS , BURTON STEPHANIE LOVE
IPC分类号： A01N65/00 , C12N15/82 , C07K14/195 , C07K14/37
摘要： The subject invention provides exciting new sources for surprising, new types of toxin complex (“TC”) proteins. The subject invention includes these new classes and types of TC proteins. The subject invention also includes polynucleotides that encode the subject proteins. The subject invention further provides vectors and cells comprising these polynucleotides. The subject invention also provides novel methods of controlling insects. The subject invention relates in part to the surprising discovery that new types of TC proteins can be obtained from a widely diverse phylogenetic spectrum of organisms including, most notably and surprisingly, eukaryotic fungus.

9. 发明专利

AU2006218516A1 New sources for, and types of, insecticidally active proteins, and polynucleotides that encode the proteins 未知
公开(公告)号：AU2006218516A1
公开(公告)日：2006-09-08
申请号：AU2006218516
申请日：2006-03-02
申请人： DOW AGROSCIENCES LLC
发明人： MEADE THOMAS , WOOSLEY AARON TODD , MERLO DONALD J , LARRINUA IGNACIO M , BURTON STEPHANIE LOVE , HEY TIMOTHY D
IPC分类号： A01N65/00 , C12N15/82 , C07K14/195 , C07K14/37
摘要： The subject invention provides exciting new sources for surprising, new types of toxin complex (“TC”) proteins. The subject invention includes these new classes and types of TC proteins. The subject invention also includes polynucleotides that encode the subject proteins. The subject invention further provides vectors and cells comprising these polynucleotides. The subject invention also provides novel methods of controlling insects. The subject invention relates in part to the surprising discovery that new types of TC proteins can be obtained from a widely diverse phylogenetic spectrum of organisms including, most notably and surprisingly, eukaryotic fungus.

10. 发明专利

BRPI0713671A2 未知
公开(公告)号：BRPI0713671A2
公开(公告)日：2013-12-03
申请号：BRPI0713671
申请日：2007-06-08
申请人： DOW AGROSCIENCES LLC
发明人： HENRY MATTHEW J , LARRINUA IGNACIO M , RUSSELL SEAN M
IPC分类号： A61K39/12 , A61K39/145
摘要： The subject invention provides novel amino acid sequences (including a consensus sequence) of the Avian Influenza A virus hemagglutinin protein. These newly constructed genes are designed to provide a broader spectrum of activity across the serotype family thus providing a basis for a vaccine that has broad heterologous disease protection. The novel genes have been further improved by the addition of strategic glycosylation sites into the amino acids sequences that they encode. These genes can also, optionally, be codon optimized for plant expression, inserted into the appropriate vector and cloned into plants for expression. Polypeptides produced by recombinant host cells or transgenic plants can also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals. Additionally, transgenic plant material may also be used as source of antigen for the formulation of vaccines for the control of influenza in susceptible individuals.

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