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1. 发明申请

WO2007002189A3 ANALYTE SENSOR 审中-公开
标题翻译：分析传感器
公开(公告)号：WO2007002189A3
公开(公告)日：2007-09-07
申请号：PCT/US2006024132
申请日：2006-06-20
申请人： DEXCOM INC , DOBBLES J MICHAEL , BRISTER MARK , BRAUKER JAMES H , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MENSINGER MICHAEL ROBERT , SAINT SEAN , SIMPSON PETER C
发明人： DOBBLES J MICHAEL , BRISTER MARK , BRAUKER JAMES H , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MENSINGER MICHAEL ROBERT , SAINT SEAN , SIMPSON PETER C
IPC分类号： A61B5/05
CPC分类号： A61B5/1451 , A61B5/0031 , A61B5/14517 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/6832 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/7264 , A61B5/742 , A61B2560/0223 , A61B2560/0276 , A61B2560/028 , A61L2/12 , A61L2/206 , Y02A90/22 , Y02A90/26 , Y10T29/49004
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. The system can include an applicator 12, a mounting unit 14, and an electronics unit 16.
摘要翻译：本发明总体上涉及用于测量宿主中的分析物的系统和方法。更具体地说，本发明涉及用于经皮测量宿主中的葡萄糖的系统和方法。该系统可以包括施加器12，安装单元14和电子单元16。

2. 发明申请

WO2006073453A2 IMPLANTABLE ANALYTE SENSOR 审中-公开
标题翻译：可植入分析传感器
公开(公告)号：WO2006073453A2
公开(公告)日：2006-07-13
申请号：PCT/US2005014696
申请日：2005-05-02
申请人： DEXCOM INC , GOODE JR PAUL V , HOLMQUIST ARNOLD L , TAPSAK MARK A , SHULTS MARK , CARR-BRENDEL VICTORIA , BRAUKER JAMES H , NEALE PAUL V , MCCLURE JASON D , BRISTER MARK , SIMPSON PETER C , RHODES RATHBUN K
发明人： GOODE JR PAUL V , HOLMQUIST ARNOLD L , TAPSAK MARK A , SHULTS MARK , CARR-BRENDEL VICTORIA , BRAUKER JAMES H , NEALE PAUL V , MCCLURE JASON D , BRISTER MARK , SIMPSON PETER C , RHODES RATHBUN K
IPC分类号： A61B5/07 , A61B5/00 , A61B5/05 , H04B1/03
CPC分类号： A61B5/0031 , A61B5/076 , A61B5/14532 , A61B5/14865 , A61B2560/04 , A61B2560/0462 , H04B1/03 , Y10T29/49117
摘要： An implantable analyte sensor (12) including a sensor body substantially formed from a water vapor permeable material and electrical components encapsulated within the sensor body, wherein the electrical components comprise RF circuitry (38) and an antenna (42) adapted for RF transmission from the sensor (12) in vivo to a receiver (14) ex vivo, wherein the RF circuitry (38) is spaced a fixed distance from the sensor body so as to support a dielectric constant that enables RF transmission between the sensor (12) in vivo to the receiver (14) ex vivo.
摘要翻译：一种可植入分析物传感器（12），其包括基本由水蒸气可渗透材料形成的传感器主体和封装在传感器主体内的电子部件，其中电子部件包括RF电路（38）和适于从传感器（12）在体内与接收器（14）离体接触，其中所述RF电路（38）与所述传感器主体间隔固定距离，以支持介电常数，所述介电常数使所述传感器（12）能够在体内到体外的接收器（14）。

3. 发明申请

WO2007120381A3 ANALYTE SENSOR 审中-公开
标题翻译：分析传感器
公开(公告)号：WO2007120381A3
公开(公告)日：2008-03-27
申请号：PCT/US2007003881
申请日：2007-02-14
申请人： DEXCOM INC , BOOCK ROBERT , RIXMAN MONICA , BRAUKER JAMES H , PETISCE JAMES R , SIMPSON PETER , BRISTER MARK , TAPSAK MARK A , CARR-BRENDEL VICTORIA
发明人： BOOCK ROBERT , RIXMAN MONICA , BRAUKER JAMES H , PETISCE JAMES R , SIMPSON PETER , BRISTER MARK , TAPSAK MARK A , CARR-BRENDEL VICTORIA
IPC分类号： A61B5/05
CPC分类号： A61B5/14865 , A61B5/0031 , A61B5/14532 , A61B5/418 , B33Y70/00
摘要： The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable devices including these membranes, for example, a continuous analyte needle-type sensor (34) including a reference electrode (30) helically wound around the working electrode (38), and covered by a membrane system (32) including a silicone-hydrophilic polymer blend membrane.
摘要翻译：本发明一般涉及与可植入装置一起使用的膜，例如用于检测生物样品中分析物浓度的装置。更具体地说，本发明涉及新颖的硅氧烷亲水性聚合物共混膜，以及包括这些膜的装置和可植入装置，例如连续的分析物针型传感器（34），其包括在工作中螺旋缠绕的参比电极（30）电极（38），并被包括硅氧烷亲水聚合物共混膜的膜系统（32）覆盖。

4. 发明申请

WO2009105337A3 CONTINUOUS MEDICAMENT SENSOR SYSTEM FOR IN VIVO USE 审中-公开
标题翻译：连续使用医疗传感器系统
公开(公告)号：WO2009105337A3
公开(公告)日：2010-12-16
申请号：PCT/US2009033096
申请日：2009-02-04
申请人： DEXCOM INC , SIMPSON PETER C , YANG RICHARD C , MATSUBARA BRADLEY SHIGETO , BOOCK ROBERT , MCCARTHY ELEANOR , BRISTER MARK
发明人： SIMPSON PETER C , YANG RICHARD C , MATSUBARA BRADLEY SHIGETO , BOOCK ROBERT , MCCARTHY ELEANOR , BRISTER MARK
IPC分类号： A61M31/00
CPC分类号： A61B5/14546 , A61B5/0002 , A61B5/064 , A61B5/14532 , A61B5/4094 , A61B5/411 , A61B5/4839 , A61B5/4848 , A61M5/1723 , A61M2005/14296 , A61M2230/201
摘要： Systems and methods for continuous measurement of a medicament In vivo are provided. In some embodiments, the system 10 is configured to provide information associated with medicament titration using continuous analyte sensor 100 and communication device 110. In some embodiments, the system Is configured for continuous ambulatory drug testing in a host ß, including a host monitor having a continuous sensor, location module, processor module and transmitter. In some embodiments, the system Is configured for continuously monitoring hormone levels and Includes a continuous hormone sensor and a communication device configured to output hormone information in real time. Another embodiment provides an analyte sensor for continuous monitoring of a host's nutritional status, and Is configured for both continuous glucose and albumin detection. The sensor system 10 is configured to interact with one or more secondary devices 120, which can be non-medical or medical devices, e.g., an infusion pump.
摘要翻译：用于连续测量药物的系统和方法提供体内。在一些实施例中，系统10被配置为使用连续分析物传感器100和通信设备110来提供与药物滴定相关联的信息。在一些实施例中，该系统被配置为用于主机ß中的连续动态药物测试，包括具有连续传感器，位置模块，处理器模块和变送器。在一些实施例中，系统被配置为连续监测激素水平，并且包括连续激素传感器和被配置为实时输出激素信息的通信装置。另一个实施方案提供了用于连续监测宿主营养状态的分析物传感器，并且被配置用于连续葡萄糖和白蛋白检测。传感器系统10被配置为与一个或多个辅助设备120相互作用，其可以是非医疗或医疗设备，例如输液泵。

5. 发明专利

JP2013099553A Method for evaluating sensor data and method for processing glucose sensor data 有权
标题翻译：用于评估传感器数据的方法和用于处理葡萄糖传感器数据的方法
公开(公告)号：JP2013099553A
公开(公告)日：2013-05-23
申请号：JP2013000959
申请日：2013-01-08
申请人： Dexcom Inc , デックスコム・インコーポレーテッド
发明人： BRISTER MARK , BRAUKER JAMES H , CODD DANIEL SHAWN , DOBBLES MICHAEL J , GUERRE JOHN A , HA VICTOR , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MCGEE THOMAS F , MENSINGER MICHAEL ROBERT , NEALE PAUL V , NOLTING JOHN E , PETERSEN DAVID MICHAEL , PETISCE JAMES R , RASDAL ANDREW , SAINT SEAN T , SIMPSON PETER C , SWANSON VANCE , THROWER JAMES PATRICK , WOO KUM MING
IPC分类号： A61B5/1473
CPC分类号： A61B5/14865 , A61B5/0002 , A61B5/14532 , A61B5/14546 , A61B5/1486 , A61B5/1495 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/743 , A61B2560/0223 , A61B2560/0252
摘要： PROBLEM TO BE SOLVED: To provide a system and method for transcutaneously measuring patient's glucose, gelerally relating to a system and a method for measuring an analyte of the patient.SOLUTION: A transcutaneous analyte sensor system 10 includes an applicator (12), a mounting unit (14), an electronics unit (16); a base (24) adapted for mounting on the skin of the patient; and one or more terminals (28) configured to provide secure electrical contact between the sensor and the electronics unit (16).
摘要翻译：要解决的问题：提供用于经皮测量患者的葡萄糖的系统和方法，其与用于测量患者的分析物的系统和方法相关。经皮分析物传感器系统10包括施用器（12），安装单元（14），电子单元（16）; 适于安装在患者皮肤上的底座（24）; 以及被配置为在传感器和电子单元（16）之间提供牢固的电接触的一个或多个端子（28）。版权所有（C）2013，JPO＆INPIT

6. 发明专利

JP2012110730A TRANSCUTANEOUS ANALYTE SENSOR 审中-公开
公开(公告)号：JP2012110730A
公开(公告)日：2012-06-14
申请号：JP2012006893
申请日：2012-01-17
申请人： DEXCOM INC
发明人： BRISTER MARK , BRAUKER JAMES H , CODD DANIEL SHAWN , DOBBLES MICHAEL J , GUERRE JOHN A , HA VICTOR , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MCGEE THOMAS F , MENSINGER MICHAEL ROBERT , NEALE PAUL V , NOLTING JOHN E , PETERSEN DAVID MICHAEL , PETISCE JAMES R , RASDAL ANDREW , SAINT SEAN T , SIMPSON PETER C , SWANSON VANCE , THROWER JAMES PATRICK , WOO KUM MING
IPC分类号： A61B5/1473 , A61B5/1486 , G01N33/66
摘要： PROBLEM TO BE SOLVED: To provide a system and a method for generally measuring an analyte of a patient, in particular, to provide a system and a method for transcutaneously measuring glucose of the patient.SOLUTION: This transcutaneous analyte sensor system 10 can include: an applicator (12); a mounting unit (14); an electronic apparatus unit (16); a base part (24) adapted for being mounted on the skin of the patient; and one or more terminals (28) configured to provide secure electrical contact between a sensor and the electronic apparatus unit (16).

7. 发明专利

JP2012213654A Transcutaneous analyte sensor 有权
标题翻译： TRANSCUTANEOUS分析仪传感器
公开(公告)号：JP2012213654A
公开(公告)日：2012-11-08
申请号：JP2012169323
申请日：2012-07-31
申请人： Dexcom Inc , デックスコム・インコーポレーテッド
发明人： BRISTER MARK , BRAUKER JAMES H , CODD DANIEL SHAWN , DOBBLES MICHAEL J , GUERRE JOHN A , HA VICTOR , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MCGEE THOMAS F , MENSINGER MICHAEL ROBERT , NEALE PAUL V , NOLTING JOHN E , PETERSEN DAVID MICHAEL , PETISCE JAMES R , RASDAL ANDREW , SAINT SEAN T , SIMPSON PETER C , SWANSON VANCE , THROWER JAMES PATRICK , WOO KUM MING
IPC分类号： A61B5/1473 , A61B5/1486 , G01N27/416 , G01N33/66
CPC分类号： A61B5/14865 , A61B5/0002 , A61B5/14532 , A61B5/14546 , A61B5/1486 , A61B5/1495 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/743 , A61B2560/0223 , A61B2560/0252
摘要： PROBLEM TO BE SOLVED: To provide a system and a method for measuring an analyte of a patient, more particularly, for transcutaneously measuring glucose of the patient.SOLUTION: This transcutaneous analyte sensor system 10 can include: an applicator (12); an installation unit (14); an electronic appliance unit (16); a base part (24) fitted such that the base part (24) is installed on the skin of the patient; and one or more terminals (28) configured to bring certain electrical contact between a sensor and the electronic appliance unit (16).
摘要翻译：要解决的问题：提供一种用于测量患者分析物的系统和方法，更具体地，用于经皮测量患者的葡萄糖。解决方案：该经皮分析物传感器系统10可以包括：施加器（12）; 安装单元（14）; 电子设备单元（16）; 基部（24），其被安装成使得所述基部（24）安装在患者的皮肤上; 以及一个或多个端子（28），其构造成在传感器和电子设备单元（16）之间产生一定的电接触。版权所有（C）2013，JPO＆INPIT

8. 发明专利

JP2014158970A Method for calibrating continuous glucose sensor and system for calibrating continuous glucose sensor 有权
标题翻译：用于校准连续葡萄糖传感器的方法和用于校准连续葡萄糖传感器的系统
公开(公告)号：JP2014158970A
公开(公告)日：2014-09-04
申请号：JP2014097447
申请日：2014-05-09
申请人： Dexcom Inc , デックスコム・インコーポレーテッド
发明人： BRISTER MARK , BRAUKER JAMES H , CODD DANIEL SHAWN , DOBBLES MICHAEL J , GUERRE JOHN A , HA VICTOR , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MCGEE THOMAS F , MENSINGER MICHAEL ROBERT , NEALE PAUL V , NOLTING JOHN E , PETERSEN DAVID MICHAEL , PETISCE JAMES R , RASDAL ANDREW , SAINT SEAN T , SIMPSON PETER C , SWANSON VANCE , THROWER JAMES PATRICK , WOO KUM MING
IPC分类号： A61B5/1473 , A61B5/1486
CPC分类号： A61B5/14865 , A61B5/0002 , A61B5/14532 , A61B5/14546 , A61B5/1486 , A61B5/1495 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/743 , A61B2560/0223 , A61B2560/0252
摘要： PROBLEM TO BE SOLVED: To provide systems and methods for measuring an analyte in a patient, and more specifically, systems and methods for transcutaneous measurement of glucose in a patient.SOLUTION: A transcutaneous analyte sensor system 10 may include an applicator (12), a mounting unit (14), an electronics unit (16), a base (24) adapted for mounting on the skin of a patient, and one or more contacts (28) configured to provide secure electrical contact between a sensor and the electronics unit (16).
摘要翻译：要解决的问题：提供用于测量患者中的分析物的系统和方法，更具体地，用于经皮测量患者体内葡萄糖的系统和方法。解剖：经皮分析物传感器系统10可包括施用器（12），安装单元（14），电子单元（16），适于安装在患者皮肤上的基座（24）以及被配置为在传感器和电子单元之间提供牢固的电接触的一个或多个触点（16）。

9. 发明专利

JP2011224381A Transcutaneous analyte sensor 有权
标题翻译： TRANSCUTANEOUS分析仪传感器
公开(公告)号：JP2011224381A
公开(公告)日：2011-11-10
申请号：JP2011121598
申请日：2011-05-31
申请人： Dexcom Inc , デックスコム・インコーポレーテッド
发明人： BRISTER MARK , BRAUKER JAMES H , CODD DANIEL SHAWN , DOBBLES MICHAEL J , GUERRE JOHN A , HA VICTOR , KAMATH APURV ULLAS , KLINE DANIEL S , MASTERSON STEVE , MCGEE THOMAS F , MENSINGER MICHAEL ROBERT , NEALE PAUL V , NOLTING JOHN E , PETERSEN DAVID MICHAEL , PETISCE JAMES R , RASDAL ANDREW , SAINT SEAN T , SIMPSON PETER C , SWANSON VANCE , THROWER JAMES PATRICK , WOO KUM MING
IPC分类号： A61B5/1473 , A61B5/1486 , G01N27/327 , G01N27/416
CPC分类号： A61B5/14865 , A61B5/0002 , A61B5/14532 , A61B5/14546 , A61B5/1486 , A61B5/1495 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/743 , A61B2560/0223 , A61B2560/0252
摘要： PROBLEM TO BE SOLVED: To provide systems and methods for measuring an analyte in a patient, more particularly, systems and methods for transcutaneous measurement of glucose in a patient.SOLUTION: A transcutaneous analyte sensor system 10 includes an applicator (12), a mounting unit (14), an electronics unit (16), a base (24) adapted for mounting on the skin of the patient, and one or more terminals (28) configured to provide secure electrical contact between the sensor and the electronics unit (16).

10. 发明申请

WO2004037443B1 STENT WITH INTERMITTENT COATING 审中-公开
标题翻译：带间歇涂层的支架
公开(公告)号：WO2004037443B1
公开(公告)日：2004-06-17
申请号：PCT/US0332441
申请日：2003-10-14
申请人： MEDTRONIC VASCULAR INC , BRISTER MARK
发明人： BRISTER MARK
IPC分类号： A61F2/00 , A61F2/86 , A61L31/10 , A61L31/16 , B05D1/00 , A61F2/06 , A61L27/14
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2250/0035 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/00
摘要： The stent with an intermittent coating of the present invention provides a coating having a plurality of discrete coating sections disposed on a stent, i.e., an intermittent coating. The individual coating sections can contain different drugs or therapeutic agents, can be made of different polymers, can be made with different solvents, or combinations thereof. The coating sections can be applied in patterns such as ring patterns, striped patterns, spotted patterns, or dot matrix patterns. In one embodiment, the regions can be large relative to the stent, such as a ring pattern including one therapeutic agent in the radial regions at the ends of a stent and a different therapeutic agent in the radial region in the middle. In another embodiment, the regions can be small relative to the stent, such as a dot matrix pattern with each grid region being a small point.
摘要翻译：本发明的具有间歇涂层的支架提供了涂层，该涂层具有设置在支架上的多个离散涂层部分，即间歇涂层。各个涂层部分可以含有不同的药物或治疗剂，可以由不同的聚合物制成，可以用不同的溶剂或其组合制成。涂布部分可以以诸如环形图案，条纹图案，斑点图案或点阵图案的图案应用。在一个实施方案中，相对于支架，这些区域可以较大，例如在支架末端的径向区域中包括一种治疗剂的环形图案，以及在中间的径向区域中的不同治疗剂。在另一个实施例中，该区域可以相对于支架较小，例如点阵模式，其中每个网格区域都是小点。

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