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1. 发明申请

WO2003045275A2 MEDICAL DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：医疗器械输送系统
公开(公告)号：WO2003045275A2
公开(公告)日：2003-06-05
申请号：PCT/US2002/038289
申请日：2002-11-27
申请人： COOK INCORPORATED , OREGON HEALTH AND SCIENCE UNIVERSITY
发明人： PAVCNIK, Dusan , CASE, Brian, C. , DIXON, Christopher, G. , FLAGLE, Jacob, A. , GARRISON, Mike , HOFFA, Andrew, K. , LEONARD, Ray, II
IPC分类号： A61F2/00
CPC分类号： A61F2/2436 , A61F2/95 , A61F2002/011 , A61F2002/9517
摘要： A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end (14) thereof, and an inner member (16) extending through the catheter and beyond the distal end thereof, to an atraumatic distal tip portion (17) forward of the catheter distal end. The inner member extends through the medical device in the device-containing region, includes a proximal portion (18) with sufficiently large diameter to prevent longitudinal movement of the device as the catheter is retracted during deployment, and centers the device upon release from the distal catheter end during deployment. The inner member is preferably radiolucent underlying the device for contrast with radiopaque markers (43) of the device. The inner member preferably includes a flat portion (35) extending from the device-containing portion to the proximal end (22) to form a passageway or lumen (21) with the delivery catheter to transmit hydrating fluid to a device such as a valve containing lyophilized tissue requiring hydration immediately prior to patient implantation.
摘要翻译：一种用于将诸如静脉瓣的医疗装置（30）植入患者脉管系统的输送系统（10）。递送系统包括具有与其远端（14）相邻的装置容纳部分（15）的输送导管（11）和延伸穿过导管并超出其远端的内部构件（16）到无创伤远端尖端部分（17）在导管远端的前方。内部构件在包含装置的区域中延伸通过医疗装置，包括具有足够大直径的近端部分（18），以在导管在展开期间缩回时防止装置的纵向移动，并且使得装置在从远端导管在部署期间结束。内部构件优选地是设备下方的射线可透以与装置的不透射线标记（43）形成对比。内部构件优选地包括从装置容纳部分延伸到近端（22）的平坦部分（35），以与输送导管形成通道或内腔（21），以将保湿流体传送到装置，例如包含在患者植入之前立即需要水合的冻干组织。

2. 发明申请

WO2003045275A3 MEDICAL DEVICE DELIVERY SYSTEM 审中-公开
公开(公告)号：WO2003045275A3
公开(公告)日：2003-06-05
申请号：PCT/US2002/038289
申请日：2002-11-27
申请人： COOK INCORPORATED , OREGON HEALTH AND SCIENCE UNIVERSITY
发明人： PAVCNIK, Dusan , CASE, Brian, C. , DIXON, Christopher, G. , FLAGLE, Jacob, A. , GARRISON, Mike , HOFFA, Andrew, K. , LEONARD, Ray, II
IPC分类号： A61F2/06
摘要： A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end (14) thereof, and an inner member (16) extending through the catheter and beyond the distal end thereof, to an atraumatic distal tip portion (17) forward of the catheter distal end. The inner member extends through the medical device in the device-containing region, includes a proximal portion (18) with sufficiently large diameter to prevent longitudinal movement of the device as the catheter is retracted during deployment, and centers the device upon release from the distal catheter end during deployment. The inner member is preferably radiolucent underlying the device for contrast with radiopaque markers (43) of the device. The inner member preferably includes a flat portion (35) extending from the device-containing portion to the proximal end (22) to form a passageway or lumen (21) with the delivery catheter to transmit hydrating fluid to a device such as a valve containing lyophilized tissue requiring hydration immediately prior to patient implantation.

3. 发明授权

EP1465546B1 MEDICAL DEVICE DELIVERY SYSTEM 有权
标题翻译：医疗设备输送系统
公开(公告)号：EP1465546B1
公开(公告)日：2007-07-18
申请号：EP02799890.5
申请日：2002-11-27
申请人： Cook Incorporated , Oregon Health and Science University
发明人： PAVCNIK, Dusan , CASE, Brian, C. , DIXON, Christopher, G. , FLAGLE, Jacob, A. , GARRISON, Mike , HOFFA, Andrew, K. , LEONARD, Ray, II
IPC分类号： A61F2/00
CPC分类号： A61F2/2436 , A61F2/95 , A61F2002/011 , A61F2002/9517
摘要： A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end (14) thereof, and an inner member (16) extending through the catheter and beyond the distal end thereof, to an atraumatic distal tip portion (17) forward of the catheter distal end. The inner member extends through the medical device in the device-containing region, includes a proximal portion (18) with sufficiently large diameter to prevent longitudinal movement of the device as the catheter is retracted during deployment, and centers the device upon release from the distal catheter end during deployment. The inner member is preferably radiolucent underlying the device for contrast with radiopaque markers (43) of the device. The inner member preferably includes a flat portion (35) extending from the device-containing portion to the proximal end (22) to form a passageway or lumen (21) with the delivery catheter to transmit hydrating fluid to a device such as a valve containing lyophilized tissue requiring hydration immediately prior to patient implantation.

4. 发明公开

EP1465546A2 MEDICAL DEVICE DELIVERY SYSTEM 有权
标题翻译：医疗设备输送系统
公开(公告)号：EP1465546A2
公开(公告)日：2004-10-13
申请号：EP02799890.5
申请日：2002-11-27
申请人： Cook Incorporated , Oregon Health and Science University
发明人： PAVCNIK, Dusan , CASE, Brian, C. , DIXON, Christopher, G. , FLAGLE, Jacob, A. , GARRISON, Mike , HOFFA, Andrew, K. , LEONARD, Ray, II
IPC分类号： A61F2/00
CPC分类号： A61F2/2436 , A61F2/95 , A61F2002/011 , A61F2002/9517
摘要： A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end (14) thereof, and an inner member (16) extending through the catheter and beyond the distal end thereof, to an atraumatic distal tip portion (17) forward of the catheter distal end. The inner member extends through the medical device in the device-containing region, includes a proximal portion (18) with sufficiently large diameter to prevent longitudinal movement of the device as the catheter is retracted during deployment, and centers the device upon release from the distal catheter end during deployment. The inner member is preferably radiolucent underlying the device for contrast with radiopaque markers (43) of the device. The inner member preferably includes a flat portion (35) extending from the device-containing portion to the proximal end (22) to form a passageway or lumen (21) with the delivery catheter to transmit hydrating fluid to a device such as a valve containing lyophilized tissue requiring hydration immediately prior to patient implantation.

5. 发明申请

WO2009009466A1 TUBULAR DEVICES HAVING REVERSIBLE COMPONENTS FOR DEPLOYMENT OF ENDOLUMINAL OCCLUDERS AND RELATED METHODS AND SYSTEMS 审中-公开
标题翻译：具有用于分泌内分泌系统的可逆组分的管状装置及相关方法和系统
公开(公告)号：WO2009009466A1
公开(公告)日：2009-01-15
申请号：PCT/US2008/069290
申请日：2008-07-07
申请人： COOK INCORPORATED , PAUL, Ram, H., Jr. , FLAGLE, Jacob, A. , CASE, Brian, C.
发明人： PAUL, Ram, H., Jr. , FLAGLE, Jacob, A. , CASE, Brian, C.
IPC分类号： A61B17/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12136 , A61B17/12181 , A61B17/1219 , A61B17/3468 , A61B2017/1205
摘要： Described are devices, methods, and systems useful for deploying one or more occlusive prostheses within the vasculature of a patient. Illustrative devices can include a deployment tube or sheath that contains an occlusive prosthesis, wherein a segment of the sheath is reversible by a user so as to deploy the prosthesis from the sheath lumen within a bodily lumen of a patient.
摘要翻译：描述了用于在患者的脉管系统内部署一个或多个闭塞假体的装置，方法和系统。示例性装置可以包括包含闭塞假体的展开管或护套，其中护套的一部分可由使用者逆转，以便将该假体从皮肤内腔部署到患者体内。

6. 发明申请

WO2007130614A2 SELF-ORIENTING DELIVERY SYSTEM 审中-公开
标题翻译：自我定向交付系统
公开(公告)号：WO2007130614A2
公开(公告)日：2007-11-15
申请号：PCT/US2007/010902
申请日：2007-05-04
申请人： COOK INCORPORATED , CASE, Brian, C. , PAUL, Ram, H., Jr.
发明人： CASE, Brian, C. , PAUL, Ram, H., Jr.
CPC分类号： A61M25/01 , A61F2/95 , A61F2002/30125 , A61F2002/30538 , A61F2230/0008 , A61F2250/0006 , A61M25/0074 , A61M25/0082
摘要： Delivery systems for delivering and deploying expandable intraluminal medical devices within a body vessel are provided. A portion of the delivery system that includes the expandable intraluminal medical device orients itself about an axis based on characteristics of the body vessel, such as the relative orientation of major and minor axes of the vessel. This allows the intraluminal medical device to be deployed in the vessel in a desired orientation relative to the vessel. Embodiments can be used with any suitable intraluminal medical device, including valve devices, stents, drug-coated stents, filters, and other suitable devices. Methods of delivering and deploying intraluminal medical devices are also described.
摘要翻译：提供了用于在身体容器内递送和部署可膨胀的管腔内医疗装置的输送系统。包括可扩张管腔内医疗装置的输送系统的一部分基于身体血管的特征（例如血管的主轴和短轴的相对取向）绕轴线定向。这允许管腔内医疗装置相对于容器以期望的方向部署在容器中。实施例可以与任何合适的管腔内医疗装置一起使用，包括瓣膜装置，支架，药物涂层的支架，过滤器和其它合适的装置。还描述了递送和部署管腔内医疗装置的方法。

7. 发明申请

WO2006028821A1 DELIVERY SYSTEM WHICH FACILITATES HYDRATION OF AN INTRALUMINAL MEDICAL DEVICE 审中-公开
标题翻译：促进肝内医疗器械水分化的输送系统
公开(公告)号：WO2006028821A1
公开(公告)日：2006-03-16
申请号：PCT/US2005/030861
申请日：2005-08-31
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , RAM, Paul, H. , SCHAEFFER, Darin, G.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , RAM, Paul, H. , SCHAEFFER, Darin, G.
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/2436 , A61F2/95 , A61F2002/011 , A61F2002/9583
摘要： Delivery systems and methods of making delivery systems are provided. A delivery system facilitates hydration of an intraluminal medical device disposed within a device chamber of the delivery system.
摘要翻译：提供了交付系统和交付系统的方法。递送系统促进置于输送系统的装置室内的管腔内医疗装置的水合。

8. 发明申请

WO2004080352A1 PROSTHETIC VALVE THAT PERMITS RETROGRADE FLOW 审中-公开
标题翻译：超过流量的溢流阀
公开(公告)号：WO2004080352A1
公开(公告)日：2004-09-23
申请号：PCT/US2004/007219
申请日：2004-03-10
申请人： COOK INCORPORATED , OSBORNE, Thomas, A. , CASE, Brian, C. , BLEYER, Mark, W.
发明人： OSBORNE, Thomas, A. , CASE, Brian, C. , BLEYER, Mark, W.
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2/2412 , A61F2/2418 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0026 , A61F2230/0095
摘要： A prosthetic valve for regulating fluid flow through a body vessel is provided. The valve includes an expandable support frame (410) and a valve leaflet (446, 448), and includes at least one opening (480) that permits a controlled amount of retrograde flow through the valve when the valve is in a closed configuration.
摘要翻译：提供了一种用于调节通过身体容器的流体流动的人造瓣膜。阀包括可膨胀支撑框架（410）和阀小叶（446,448），并且包括至少一个开口（480），当阀处于关闭构型时允许控制量的逆流流过阀。

9. 发明申请

WO2008121380A1 MEDICAL DEVICE DELIVERY SYSTEM WITH SHEATH SEPARATION 审中-公开
标题翻译：医疗器械输送系统与分离
公开(公告)号：WO2008121380A1
公开(公告)日：2008-10-09
申请号：PCT/US2008/004157
申请日：2008-03-31
申请人： COOK INCORPORATED , HOFFMAN, Grant, T. , CASE, Brian, C.
发明人： HOFFMAN, Grant, T. , CASE, Brian, C.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/958 , A61F2/97
摘要： Medical device delivery systems and associated methods are provided. Delivery systems according to the invention include an elongated tubular member and a body member, such as a dilator, disposed therein. An intraluminal medical device is disposed on the dilator and within the tubular member prior to deployment. The delivery system includes a means for separating two or more portions of the distal end of the tubular member that aids in deploying the intraluminal medical device from the delivery system by separating two or more portions of the tubular member from each other to facilitate release of the intraluminal medical device from the body member. Various structures can be used for means for separating, including a cutting ring, activateable material on the tubular member, or other suitable structure. The provided devices and methods reduce friction occuring from relative movement between the sheath and dilator during deployment.
摘要翻译：提供医疗器械输送系统及相关方法。根据本发明的递送系统包括细长管状构件和布置在其中的诸如扩张器的主体构件。在展开之前，将管腔内医疗装置设置在扩张器上并在管状构件内。递送系统包括用于分离管状构件的远端的两个或更多个部分的装置，其通过将管状构件的两个或更多个部分彼此分离来有助于将管腔内医疗装置从输送系统展开以便于释放管腔内医疗器械从身体成员。各种结构可以用于分离的装置，包括切割环，管状构件上的可激活材料或其他合适的结构。所提供的装置和方法减少在展开期间由护套和扩张器之间的相对运动发生的摩擦力。

10. 发明申请

WO2006062862A1 INFLATABLE OCCLUSION DEVICES, METHODS, AND SYSTEMS 审中-公开
标题翻译：充气闭塞装置，方法和系统
公开(公告)号：WO2006062862A1
公开(公告)日：2006-06-15
申请号：PCT/US2005/043822
申请日：2005-12-06
申请人： COOK INCORPORATED , FLAGLE, Jacob , PAUL, Ram, H. , CASE, Brian, C.
发明人： FLAGLE, Jacob , PAUL, Ram, H. , CASE, Brian, C.
IPC分类号： A61L29/00
CPC分类号： A61L29/005 , A61B17/12109 , A61B17/12136 , A61B17/1219 , A61B2017/1205
摘要： Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment and filling of an inflatable occlusion device via a percutaneous procedure, so as to occlude or obliterate a portion of a vascular vessel.
摘要翻译：描述了用于实现血管血管闭塞的装置，方法和系统。经皮手术可用于阻塞和消除更大的隐静脉，例如用于治疗由静脉回流引起的静脉曲张。某些实施方案包括经由经皮过程部署和填充可膨胀闭塞装置，以便闭塞或消除血管容器的一部分。

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