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1. 发明申请

WO2006028821A1 DELIVERY SYSTEM WHICH FACILITATES HYDRATION OF AN INTRALUMINAL MEDICAL DEVICE 审中-公开
标题翻译：促进肝内医疗器械水分化的输送系统
公开(公告)号：WO2006028821A1
公开(公告)日：2006-03-16
申请号：PCT/US2005/030861
申请日：2005-08-31
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , RAM, Paul, H. , SCHAEFFER, Darin, G.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , RAM, Paul, H. , SCHAEFFER, Darin, G.
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/2436 , A61F2/95 , A61F2002/011 , A61F2002/9583
摘要： Delivery systems and methods of making delivery systems are provided. A delivery system facilitates hydration of an intraluminal medical device disposed within a device chamber of the delivery system.
摘要翻译：提供了交付系统和交付系统的方法。递送系统促进置于输送系统的装置室内的管腔内医疗装置的水合。

2. 发明申请

WO2004096100A1 ARTIFICIAL VALVE PROSTHESIS WITH IMPROVED FLOW DYNAMICS 审中-公开
标题翻译：人工阀门改进流动动力学
公开(公告)号：WO2004096100A1
公开(公告)日：2004-11-11
申请号：PCT/US2004/012430
申请日：2004-04-21
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , HOFFA, Andrew, K. , SCHAEFFER, Darin, G.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , GARRISON, Michael, L. , HOFFA, Andrew, K. , SCHAEFFER, Darin, G.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2002/068 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054 , A61F2230/0076 , A61F2230/0078 , A61F2230/008 , A61F2250/0037 , A61F2250/0039
摘要： An expandable venous valve having a support structure (11) that configured to enlarge the area adjacent to the valve structure (12) such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus (34) adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
摘要翻译：一种具有支撑结构（11）的可膨胀静脉瓣，所述支撑结构（11）构造成扩大邻近所述瓣膜结构（12）的区域，使得逆行流的流动模式被改变为有利于在阀门区域，以防止静脉系统中的体液停滞，可导致血栓形成。可以通过在两个支撑框架部分之间的血管壁的无支撑部分中形成邻近阀结构的人造窦（34）来产生扩大的口袋区域，或者支撑框架可以包括形成人造窦的扩张直径的中间或近端部分邻近阀门结构。在另一组实施例中，相对的小叶和支撑框架和/或血管壁之间的附接通路包括近端部分，其将小叶彼此延伸接触，并且远端部分相对于相邻壁形成大角度，在传单的底部创造了一个大口袋。在一个实施例中，附接通道沿着一对基本上平行的纵向连接支柱向远侧延伸以产生延伸的小叶接触区域，然后沿着远侧连接支柱周向地和远端地从前者角度定位以限定传单的底部边缘。

3. 发明申请

WO2006026377A1 DELIVERY SYSTEM WITH CONTROLLED FRICTIONAL PROPERTIES 审中-公开
标题翻译：具有受控摩擦特性的输送系统
公开(公告)号：WO2006026377A1
公开(公告)日：2006-03-09
申请号：PCT/US2005/030300
申请日：2005-08-24
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A.
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9583 , A61F2002/9665
摘要： Delivery systems and methods of making delivery systems are provided. A delivery system according to the invention facilitates delivery of an intraluminal medical device (28) to a point of treatment in a body vessel. A dilator (20) includes a means (44) for resisting relative movement between an associated intraluminal medical device (28) and the dilator (20) during relative movement between the dilator and an associated tubular member (12) disposed about the dilator.
摘要翻译：提供了交付系统和交付系统的方法。根据本发明的递送系统便于将管腔内医疗装置（28）输送到体内容器中的治疗点。扩张器（20）包括用于在扩张器和围绕扩张器设置的相关联的管状构件（12）之间的相对运动期间抵抗相关联的管腔内医疗装置（28）和扩张器（20）之间的相对运动的装置（44）。

4. 发明申请

WO2009009466A1 TUBULAR DEVICES HAVING REVERSIBLE COMPONENTS FOR DEPLOYMENT OF ENDOLUMINAL OCCLUDERS AND RELATED METHODS AND SYSTEMS 审中-公开
标题翻译：具有用于分泌内分泌系统的可逆组分的管状装置及相关方法和系统
公开(公告)号：WO2009009466A1
公开(公告)日：2009-01-15
申请号：PCT/US2008/069290
申请日：2008-07-07
申请人： COOK INCORPORATED , PAUL, Ram, H., Jr. , FLAGLE, Jacob, A. , CASE, Brian, C.
发明人： PAUL, Ram, H., Jr. , FLAGLE, Jacob, A. , CASE, Brian, C.
IPC分类号： A61B17/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12136 , A61B17/12181 , A61B17/1219 , A61B17/3468 , A61B2017/1205
摘要： Described are devices, methods, and systems useful for deploying one or more occlusive prostheses within the vasculature of a patient. Illustrative devices can include a deployment tube or sheath that contains an occlusive prosthesis, wherein a segment of the sheath is reversible by a user so as to deploy the prosthesis from the sheath lumen within a bodily lumen of a patient.
摘要翻译：描述了用于在患者的脉管系统内部署一个或多个闭塞假体的装置，方法和系统。示例性装置可以包括包含闭塞假体的展开管或护套，其中护套的一部分可由使用者逆转，以便将该假体从皮肤内腔部署到患者体内。

5. 发明申请

WO2006050537A2 METHODS FOR TREATING VALVE-ASSOCIATED REGIONS OF VASCULAR VESSELS 审中-公开
标题翻译：用于治疗血管相关区域的方法
公开(公告)号：WO2006050537A2
公开(公告)日：2006-05-11
申请号：PCT/US2005/042140
申请日：2005-11-03
申请人： COOK INCORPORATED , COOK BIOTECH INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A. , HILES, Michael, C. , OBERMILLER, F. Joseph , PATEL, Umesh
发明人： CASE, Brian, C. , FLAGLE, Jacob, A. , HILES, Michael, C. , OBERMILLER, F. Joseph , PATEL, Umesh
IPC分类号： A61F2/24 , A61L27/54
CPC分类号： A61F2/2475 , A61L27/3604 , A61L27/3633 , A61L27/3641 , A61L27/3645 , A61L27/3839

6. 发明申请

WO2006050459A2 METHODS AND SYSTEMS FOR MODIFYING VASCULAR VALVES 审中-公开
标题翻译：用于修补血管的方法和系统
公开(公告)号：WO2006050459A2
公开(公告)日：2006-05-11
申请号：PCT/US2005/039834
申请日：2005-10-27
申请人： COOK INCORPORATED , FLAGLE, Jacob, A. , CASE, Brian, C.
发明人： FLAGLE, Jacob, A. , CASE, Brian, C.
IPC分类号： A61B17/00 , A61F2/24
CPC分类号： A61B17/00234 , A61B17/00491 , A61B17/064 , A61B17/122 , A61B18/1492 , A61B2017/00783 , A61F2/06 , A61F2/2475 , Y10S623/904

7. 发明申请

WO2005011534A1 PROSTHETIC VALVE DEVICES AND METHODS OF MAKING SUCH DEVICES 审中-公开
标题翻译：前置阀装置和制造这种装置的方法
公开(公告)号：WO2005011534A1
公开(公告)日：2005-02-10
申请号：PCT/US2004/024730
申请日：2004-07-30
申请人： COOK INCORPORATED , CASE, Brian, C. , FLAGLE, Jacob, A.
发明人： CASE, Brian, C. , FLAGLE, Jacob, A.
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2475 , A61F2220/0075
摘要： Prosthetic valve devices for implantation in body vessels, and methods of making same, are provided. The device has a main body (11) with first (12) and second (13) ends and defining a lumen (14), with the second end being inverted into the lumen. A valve is disposed at the second end (15). In multiple valve devices, valves are disposed at the first and second ends, and individually may be inverted into the lumen. The prosthetic valve devices may further include a support structure such as a stent (40). Methods of making a prosthetic valve device include providing a main body having first and second ends and defining a lumen, forming a valve at the second end, and inverting the second end into the lumen. Methods may further comprise forming multiple valves and may also include attaching a support structure.
摘要翻译：提供用于植入体内血管的假体瓣膜装置及其制造方法。该装置具有主体（11），其具有第一端（12）和第二端（13）端部并且限定内腔（14），其中第二端被倒置成内腔。阀设置在第二端（15）处。在多个阀装置中，阀设置在第一和第二端处，并且可以单独地倒置到内腔中。假体瓣膜装置还可以包括诸如支架（40）的支撑结构。制造假体瓣膜装置的方法包括提供具有第一端和第二端并限定内腔的主体，在第二端形成阀，并将第二端翻转成内腔。方法还可以包括形成多个阀并且还可以包括附接支撑结构。

8. 发明申请

WO2007147127A3 METHODS, SYSTEMS, AND DEVICES FOR THE DELIVERY OF ENDOLUMINAL PROSTHESES 审中-公开
公开(公告)号：WO2007147127A3
公开(公告)日：2007-12-21
申请号：PCT/US2007/071360
申请日：2007-06-15
申请人： COOK INCORPORATED , PAUL, Ram, H. , CASE, Brian, C. , FLAGLE, Jacob, A.
发明人： PAUL, Ram, H. , CASE, Brian, C. , FLAGLE, Jacob, A.
IPC分类号： A61B17/12 , A61L31/14 , A61B17/22
摘要： Described are devices, methods, and systems for achieving occlusion of vascular vessels. Further described are certain reduced or low profile procedures and devices for the percutaneous occlusion of the saphenous vein, such as in the treatment of a varicose vein condition caused by venous reflux.

9. 发明申请

WO2006062976A2 METHODS FOR MODIFYING VASCULAR VESSEL WALLS 审中-公开
标题翻译：修改血管壁水的方法
公开(公告)号：WO2006062976A2
公开(公告)日：2006-06-15
申请号：PCT/US2005/044129
申请日：2005-12-07
申请人： COOK INCORPORATED , CASE, Brian, C. , HILES, Michael, C. , FLAGLE, Jacob, A. , OBERMILLER, F., Joseph , PATEL, Umesh
发明人： CASE, Brian, C. , HILES, Michael, C. , FLAGLE, Jacob, A. , OBERMILLER, F., Joseph , PATEL, Umesh
IPC分类号： A61F2/06
CPC分类号： A61B17/12 , A61F2/07 , A61F2/2475 , A61F2002/075 , A61F2002/077

10. 发明申请

WO2006041972A3 MEDICAL DEVICE WITH BIOACTIVE AGENT 审中-公开
公开(公告)号：WO2006041972A3
公开(公告)日：2006-04-20
申请号：PCT/US2005/035912
申请日：2005-10-06
申请人： COOK INCORPORATED , OSBORNE, Thomas, A. , FLAGLE, Jacob, A. , CASE, Brian, C. , OBERMILLER, Joseph, F. , PAUL, Ram, H.
发明人： OSBORNE, Thomas, A. , FLAGLE, Jacob, A. , CASE, Brian, C. , OBERMILLER, Joseph, F. , PAUL, Ram, H.
IPC分类号： A61F2/24
摘要： Medical devices with one or more bioactive agents are provided for regulating fluid flow through a body vessel. Medical devices according to the invention can comprise prosthetic valves (10) that include a bioactive agent.

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