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1. 发明授权

US06527872B1 Environmentally friendly peracetic acid decontamination formula with increased performance and chemical stability 有权
标题翻译：环保型过乙酸去污配方，性能和化学稳定性提高
公开(公告)号：US06527872B1
公开(公告)日：2003-03-04
申请号：US09974499
申请日：2001-10-10
申请人： Christopher M. Fricker , Brian C. Wojcieck , Stephanie A. S. Harrington , Iain F. McVey , George E. Grignol
发明人： Christopher M. Fricker , Brian C. Wojcieck , Stephanie A. S. Harrington , Iain F. McVey , George E. Grignol
IPC分类号： B08B304
CPC分类号： A61L2/186 , A61B1/123 , A61B90/70 , A61B2090/701 , A61L2202/14 , A61L2202/17 , A61L2202/24 , B08B3/02 , B08B3/04 , C11D3/0073 , C11D3/128 , C11D3/3907 , C11D3/3942 , C11D3/3945 , C11D3/48
摘要： An environmentally friendly decontaminant solution, which may be disposed of after use without posing significant environmental hazards, is formulated without molybdenum-based corrosion inhibitors and preferably is free of all heavy metals. A zeolite-based buffering system optionally replaces phosphate buffers for maintaining the pH of the decontaminant solution at an appropriate pH for effective antimicrobial decontamination. Molybdenum-free decontaminant solutions containing peracetic acid retain their peracetic acid levels, and thus their antimicrobial effectiveness, for longer periods than comparable solutions formulated with a molybdate corrosion inhibitor.
摘要翻译：无需使用钼基腐蚀抑制剂即可配制环保型去污剂溶液，其可在使用后处理而不造成重大环境危害，并且优选不含所有重金属。基于沸石的缓冲系统任选地替代磷酸盐缓冲液，以将去污剂溶液的pH保持在适当的pH下以进行有效的抗菌去污。含有过乙酸的无钼净化剂溶液比用钼酸盐腐蚀抑制剂配制的可比溶液保持其过乙酸水平，因此保持其抗微生物效力更长的时间。

2. 发明授权

US06797681B2 Environmentally friendly peracetic acid decontamination formula with increased performance and chemical stability 有权
标题翻译：环保型过乙酸去污配方，性能和化学稳定性提高
公开(公告)号：US06797681B2
公开(公告)日：2004-09-28
申请号：US10300108
申请日：2002-11-20
申请人： Christopher M. Fricker , Brian C. Wojcieck , Stephanie A. S. Harrington , Iain F. McVey , George E. Grignol
发明人： Christopher M. Fricker , Brian C. Wojcieck , Stephanie A. S. Harrington , Iain F. McVey , George E. Grignol
IPC分类号： C11D308
CPC分类号： A61L2/186 , A61B1/123 , A61B90/70 , A61B2090/701 , A61L2202/14 , A61L2202/17 , A61L2202/24 , B08B3/02 , B08B3/04 , C11D3/0073 , C11D3/128 , C11D3/3907 , C11D3/3942 , C11D3/3945 , C11D3/48
摘要： An environmentally friendly decontaminant solution, which may be disposed of after use without posing significant environmental hazards, is formulated without molybdenum-based corrosion inhibitors and preferably is free of all heavy metals. A zeolite-based buffering system optionally replaces phosphate buffers for maintaining the pH of the decontaminant solution at an appropriate pH for effective antimicrobial decontamination. Molybdenum-free decontaminant solutions containing peracetic acid retain their peracetic acid levels, and thus their antimicrobial effectiveness, for longer periods than comparable solutions formulated with a molybdate corrosion inhibitor.
摘要翻译：无需使用钼基腐蚀抑制剂即可配制环保型去污剂溶液，其可在使用后处理而不造成重大环境危害，并且优选不含所有重金属。基于沸石的缓冲系统任选地替代磷酸盐缓冲液，以将去污剂溶液的pH保持在适当的pH下以进行有效的抗菌去污。含有过乙酸的无钼净化剂溶液比用钼酸盐腐蚀抑制剂配制的可比溶液保持其过乙酸水平，因此保持其抗微生物效力更长的时间。

3. 发明授权

US06749807B1 Flow through chemical indicator for measurement of active biocidal agents in a single use package 失效
标题翻译：流通化学指示剂，用于单次使用包装中活性杀生物剂的测量
公开(公告)号：US06749807B1
公开(公告)日：2004-06-15
申请号：US09314497
申请日：1999-05-19
申请人： Brian E. Schindly , Christopher M. Fricker , George E. Grignol
发明人： Brian E. Schindly , Christopher M. Fricker , George E. Grignol
IPC分类号： B01L300
CPC分类号： A61L2/28 , A61L2/186 , A61L2202/122 , A61L2202/24 , Y10T436/115831 , Y10T436/12
摘要： A single-use cartridge C contains a dose of a concentrated decontaminant for providing a decontaminant solution upon mixing with water. The cartridge is inserted into the well (16) of a decontamination system (A). Fresh water and then the decontaminant solution are recirculated through the well during a decontamination cycle. The cartridge includes a porous region (42), through which the decontaminant solution flows. Impregnated in the porous region is a chemical indicator (44), such as crystal violet, which gradually changes color on exposure to the decontaminant. The indicator provides a semi-quantitative indication of the integrated level of the decontaminant in the solution over time for determining whether an acceptable level of the decontaminant was present for decontamination. A preferred embodiment of the cartridge C includes nested inner and outer water-penetrable cups (50,150,70,170) for holding first and second reagents. The two cups are sealed together adjacent upper open ends (56,92,156,192). A porous top cover (94, 194) is sealed to the inner cup adjacent the inner cup open end (92, 192) to complete the cartridge. The two reagents react with water flowing through the cartridge to form the decontaminant solution. The chemical indicator is printed on the top cover so that it is exposed to the decontaminant solution as it is recirculated through the cartridge.
摘要翻译：一次性盒C含有一定量的浓缩去污剂，用于在与水混合时提供去污剂溶液。墨盒插入去污系统（A）的孔（16）中。然后在净化循环期间，将净水然后净化剂溶液再循环通过井。药筒包括多孔区域（42），净化剂溶液流过该多孔区域。浸渍在多孔区域中的是化学指示剂（44），例如结晶紫，其在暴露于去污剂时逐渐改变颜色。该指标提供了解决方案中去污剂在一段时间内的综合水平的半定量指示，用于确定是否存在可消除去污剂水平的去污剂。盒C的优选实施例包括用于保持第一和第二试剂的嵌套的内部和外部水可渗透杯（50,150,70,170）。两个杯子相邻的上开口端部密封在一起（56,92,156,192）。多孔顶盖（94,194）与邻近内杯开口端（92,192）的内杯密封，以完成料筒。两种试剂与流过滤筒的水反应形成去污剂溶液。化学品指示剂印刷在顶盖上，使其在通过墨盒再循环时暴露于净化剂溶液中。

4. 发明申请

US20130029884A1 BIOCIDE FORMULATIONS 审中-公开
标题翻译：生物制剂
公开(公告)号：US20130029884A1
公开(公告)日：2013-01-31
申请号：US13555799
申请日：2012-07-23
申请人： Paul S. Malchesky , George E. Grignol , J. Lloyd Breedlove
发明人： Paul S. Malchesky , George E. Grignol , J. Lloyd Breedlove
IPC分类号： C09K8/86 , A01N31/12 , A01P1/00 , A01N65/06
CPC分类号： A01N31/08 , C09K8/035 , C09K8/602 , C09K8/605 , C09K8/68 , A01N25/04 , A01N31/04 , A01N65/00 , A01N65/06 , A01N2300/00
摘要： Biocide compositions comprising biocide, surfactant, and solubilizing agent. The preferred biocide is parachlorometaxylenol. The biocide composition is useful in oil and gas drilling operations, such as hydraulic fracturing, as well as treating aqueous slurries in ore mining operations. The biocide compositions are effective in controlling microorganisms even in the presence of high salt content water and at high temperatures.
摘要翻译：杀生物剂组合物包含杀生物剂，表面活性剂和增溶剂。优选的杀生物剂是对氯二甲苯酚。杀生物剂组合物可用于石油和天然气钻井作业，如水力压裂，以及在采矿作业中处理含水浆料。杀菌剂组合物即使在高含盐量的水和高温下也能有效控制微生物。

5. 发明授权

US5518927A Instrument sterilation life-span indicator 失效
标题翻译：仪器灭菌寿命指标
公开(公告)号：US5518927A
公开(公告)日：1996-05-21
申请号：US291989
申请日：1994-08-17
申请人： Paul S. Malchesky , George E. Grignol
发明人： Paul S. Malchesky , George E. Grignol
IPC分类号： A61L2/26 , A61B17/00 , A61L2/28 , A61L29/14 , A61L31/00 , A61L31/14 , G01N31/22
CPC分类号： G01N31/226 , A61L2/28 , A61L29/14 , A61L31/14 , A61B2090/0814
摘要： A pigment such as crystal violet is impregnated in or otherwise affixed to a translucent plastic or porous member (14, 22). The color change material changes at least one of opacity or color with repeated exposure to a fluid sterilant, such as an oxidant solution. A label (10, 24) is mounted behind the translucent plastic material and carries an indicia (12, 26). With repeated sterilizations of the instrument, the color change material becomes progressively more translucent, allowing the indicia to be read through the translucent plastic material. When the indicia becomes visible, such as after about 7 sterilization cycles in FIG. 3, the user is warned to discontinue use of the instrument, either discarding it or having it rebuilt. Rather than having a written indicia, a color scale (30) can be provided for comparison against the current color of the color change material. When the color changes to the discard color on the color scale, the user is again advised to discontinue use of or rebuild the instrument.
摘要翻译：将诸如结晶紫的颜料浸入或以其他方式固定在半透明的塑料或多孔构件（14,22）上。颜色变化材料通过重复暴露于流体灭菌剂如氧化剂溶液来改变不透明度或颜色中的至少一种。标签（10,24）安装在半透明塑料材料的后面，并带有一个标记（12,26）。随着仪器的反复灭菌，变色材料变得越来越透明，允许通过半透明塑料材料读取标记。当标记变得可见时，例如图3中的约7次灭菌循环之后。 3，警告用户停止使用仪器，丢弃或重建仪器。可以提供用于与颜色变化材料的当前颜色进行比较的颜色标尺（30）而不是具有书写标记。当颜色在颜色标度上改变为丢弃颜色时，再次建议用户停止使用或重建仪器。

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