专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060063038A1 Holographic sensor 失效
标题翻译：全息传感器
公开(公告)号：US20060063038A1
公开(公告)日：2006-03-23
申请号：US10545275
申请日：2004-02-13
申请人： Christopher Lowe , Jeffrey Blyth , Satyamoorthy Kabilan , Abid Hussain , Xiaoping Yang , Felicity Sartain , Mei-Ching Lee
发明人： Christopher Lowe , Jeffrey Blyth , Satyamoorthy Kabilan , Abid Hussain , Xiaoping Yang , Felicity Sartain , Mei-Ching Lee
IPC分类号： B32B27/00 , G02B5/32 , B32B9/04
CPC分类号： G03H1/02 , G02B5/32 , G03H2260/12 , Y10T436/143333 , Y10T436/144444
摘要： A sensor for the detection of an analyte comprising a cis-diol moiety, which comprises a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, and wherein the medium is a polymer comprising a group of formula (I): wherein n is 0, 1, 2, 3 or 4; each X (if present) is independently is an atom or group which, viaan electronic effect, promotes formation of a tetrahedral geometry about the boron atom; and Y is a spacer which, when n is 0 or otherwise optionally, is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom. Such a sensor may be used for the detection of glucose.
摘要翻译：一种用于检测包含顺式二醇部分的分析物的传感器，其包括全息元件，该全息元件包括介质和设置在介质的整个体积中的全息图，其中该元件的光学特性由于介质是包含式（I）的基团的聚合物：其中n为0,1,2,3或4; 每个X（如果存在）独立地是通过电子效应促进围绕硼原子形成四面体几何形状的原子或基团; 并且Y是间隔基，当n为0或以其它方式任选时，其是通过电子效应促进围绕硼原子形成四面体几何形状的原子或基团。这种传感器可用于检测葡萄糖。

2. 发明申请

US20080020478A1 Method of Detecting an Analyte Using a Holographic Sensor 审中-公开
标题翻译：使用全息传感器检测分析物的方法
公开(公告)号：US20080020478A1
公开(公告)日：2008-01-24
申请号：US11597983
申请日：2005-06-06
申请人： Christopher Lowe , Satyamoorthy Kabilan , Mei-Ching Lee
发明人： Christopher Lowe , Satyamoorthy Kabilan , Mei-Ching Lee
IPC分类号： G01N33/66 , A61B3/10 , G01N21/00 , G02B5/32 , G01N21/01
CPC分类号： G01N21/4788 , G01N21/75 , G03H1/0005 , G03H1/0011 , G03H1/0248 , G03H2001/0033 , G03H2210/55 , G03H2270/55 , Y10T436/20
摘要： A method for the detection of an analyte in a fluid, which comprises contacting the fluid with a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, and wherein the variation arises as a result of interaction between the medium and the analyte; and detecting any change of the optical characteristic of the element; wherein (a) the medium comprises a group which is capable of reacting with the analyte, wherein the analyte or the group is capable of existing in a plurality of forms, and the detecting is conducted in the presence of a first catalyst which is capable of catalysing the conversion of a relatively less reactive form of the analyte or group to a relatively more reactive form; or (b) the fluid comprises a component, other than the analyte, which is capable of interacting with the medium, and the detecting is conducted in the presence of a second catalyst capable of catalysing the removal of said component.
摘要翻译：一种用于检测流体中的分析物的方法，其包括使流体与包括介质的全息元件和设置在介质的整个体积中的全息图接触，其中元件的光学特性由于变化而变化在介质的整个体积中发生的物理性质，并且其中由于介质和分析物之间的相互作用而产生变化; 并检测元件的光学特性的任何变化; 其中（a）所述培养基包括能够与分析物反应的基团，其中所述分析物或所述基团能够以多种形式存在，并且所述检测在第一催化剂存在下进行，所述第一催化剂能够催化相对较少反应性形式的分析物或基团转化成相对更具反应性的形式; 或（b）流体包含能够与介质相互作用的分析物以外的成分，并且在能够催化除去所述成分的第二催化剂的存在下进行检测。

3. 发明申请

US20060166350A1 Method of detecting an analyte in a fluid 失效
标题翻译：检测流体中分析物的方法
公开(公告)号：US20060166350A1
公开(公告)日：2006-07-27
申请号：US10509782
申请日：2003-04-04
申请人： Christopher Lowe , Colin Davidson , Jeffrey Blyth , Satyamoorthy Kabilan , Alexander Marshall , Banca Madrigal Gonzalez , Anthony James
发明人： Christopher Lowe , Colin Davidson , Jeffrey Blyth , Satyamoorthy Kabilan , Alexander Marshall , Banca Madrigal Gonzalez , Anthony James
IPC分类号： C12M1/34
CPC分类号： G02B5/32 , G01N21/05 , G01N21/4788 , G01N2021/7723 , G03H1/0248 , G03H2001/0044 , Y10S435/808 , Y10S436/805
摘要： A method for the detection of an analyte in a fluid, comprising contacting the fluid with a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, wherein the variation arises as a result of interaction between the medium and the analyte, and wherein the reaction and the variation are reversible; and detecting any change of the optical characteristic.
摘要翻译：一种用于检测流体中的分析物的方法，包括使所述流体与包括介质的全息元件和设置在所述介质的整个体积中的全息图接触，其中所述元件的光学特性由于a的变化而变化在介质的整个体积中发生的物理性质，其中由于介质和分析物之间的相互作用而产生变化，并且其中反应和变化是可逆的; 并检测光学特性的任何变化。

4. 发明申请

US20070153343A1 Holographic sensor 审中-公开
标题翻译：全息传感器
公开(公告)号：US20070153343A1
公开(公告)日：2007-07-05
申请号：US10565094
申请日：2004-07-21
申请人： Jeffrey Blyth , Christopher Lowe , Colin Alexander Davidson , Satyamoorthy Kabilan , Catherine Dobson
发明人： Jeffrey Blyth , Christopher Lowe , Colin Alexander Davidson , Satyamoorthy Kabilan , Catherine Dobson
IPC分类号： G02B5/32
CPC分类号： G01N21/4788 , G02B5/32 , G03H1/0005 , G03H2001/0033 , G03H2001/0044 , G03H2001/0417 , G03H2001/043 , G03H2001/0432 , G03H2001/0439 , G03H2001/2615 , G03H2222/16 , G03H2270/21
摘要： A sensor (8) comprises a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the hologram changes as a result of a variation of a physical property of the medium, and wherein the hologram is formed as a non-planar mirror.
摘要翻译：传感器（8）包括介质和设置在介质的整个体积中的全息图，其中由于介质的物理性质的变化，全息图的光学特性改变，并且其中全息图形成为非平面镜。

5. 发明申请

US20060127898A1 Holographic sensor based on a volume hologram in a porous medium 审中-公开
标题翻译：基于多孔介质中的体积全息图的全息传感器
公开(公告)号：US20060127898A1
公开(公告)日：2006-06-15
申请号：US10509781
申请日：2003-04-04
申请人： Christopher Lowe , Colin Davidson , Jeffrey Blyth , Satyamoorthy Kabilan , Alexander Marshall , Blanca Madrigal Gonzalez , Anthony James
发明人： Christopher Lowe , Colin Davidson , Jeffrey Blyth , Satyamoorthy Kabilan , Alexander Marshall , Blanca Madrigal Gonzalez , Anthony James
IPC分类号： G03H1/00 , C12Q1/68
CPC分类号： G01N21/7703 , G01N21/4788 , G02B5/32 , G03H2001/0044 , G03H2250/44 , G03H2270/53
摘要： A sensor for the detection of an analyte, comprising a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the hologram changes as a result of a variation of a physical property occurring throughout the volume of the medium, wherein the medium is obtainable by formation in situ in the presence of a pore-forming agent, wherein the agent is not present in the sensor or does not react with the analyte and the sensor.
摘要翻译：一种用于检测分析物的传感器，包括全息元件，该全息元件包括介质和设置在介质整个体积中的全息图，其中全息图的光学特性由于在整个体积内发生的物理性质的变化而改变介质，其中介质可以通过在成孔剂存在下原位形成而获得，其中该试剂不存在于传感器中或不与分析物和传感器反应。

6. 发明授权

US08399483B2 Quinoxaline and quinoline derivatives as kinase inhibitors 有权
标题翻译：喹喔啉和喹啉衍生物作为激酶抑制剂
公开(公告)号：US08399483B2
公开(公告)日：2013-03-19
申请号：US12809394
申请日：2008-12-17
申请人： Daniel Rees Allen , George Martin Buckley , Roland Bürli , John Richard Davenport , Natasha Kinsella , Christopher James Lock , Christopher Lowe , Stephen Robert Mack , William Ross Pitt , Andrew James Ratcliffe , Marianna Dilani Richard , Verity Margaret Sabin , Andrew Sharpe , Laura Jane Tait , Graham John Warrellow , Sophie Caroline Williams
发明人： Daniel Rees Allen , George Martin Buckley , Roland Bürli , John Richard Davenport , Natasha Kinsella , Christopher James Lock , Christopher Lowe , Stephen Robert Mack , William Ross Pitt , Andrew James Ratcliffe , Marianna Dilani Richard , Verity Margaret Sabin , Andrew Sharpe , Laura Jane Tait , Graham John Warrellow , Sophie Caroline Williams
IPC分类号： A61K31/47
CPC分类号： C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D473/34 , C07D473/36
摘要： A series of heteroaryl-substituted quinoxaline and quinoline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions, said substituted derivatives having the general formula
摘要翻译：因此，作为PI3激酶的选择性抑制剂的一系列杂芳基取代的喹喔啉和喹啉衍生物在医学中是有益的，例如在治疗炎性，自身免疫，心血管，神经退行性，代谢性，肿瘤学，伤害性感受性或眼科疾病中，所述具有通式的取代衍生物

7. 发明申请

US20060051733A1 Monitoring of cells 审中-公开
标题翻译：监测细胞
公开(公告)号：US20060051733A1
公开(公告)日：2006-03-09
申请号：US10520323
申请日：2003-07-09
申请人： Christopher Lowe , Craig Gershater , Colin Alexander Davidson
发明人： Christopher Lowe , Craig Gershater , Colin Alexander Davidson
IPC分类号： C12Q1/00 , C12Q1/34 , C12M1/34
CPC分类号： G01N33/5005 , B01L3/502707 , B01L2200/0647 , B01L2200/10 , B01L2300/0627 , B01L2300/0645 , B01L2300/0861 , B01L2300/163 , B01L2300/165 , C12Q1/04 , G01N2015/0088 , G01N2015/1006 , G01N2015/1486
摘要： A method for monitoring cells in a microfluidic-device, wherein the device includes a chamber comprising a sensor, and the monitoring is under conditions such that attachment of cells to the surface of the chamber is inhibited.
摘要翻译：一种用于监测微流体装置中的细胞的方法，其中所述装置包括包含传感器的腔室，并且所述监测处于使细胞附着到所述腔室表面受到限制的条件下。

8. 发明申请

US20050014678A1 Novel triazine-based detoxification agents and their use 审中-公开
标题翻译：新型三嗪类除毒剂及其用途
公开(公告)号：US20050014678A1
公开(公告)日：2005-01-20
申请号：US10914687
申请日：2004-08-09
申请人： Christopher Lowe , Kim Lawden
发明人： Christopher Lowe , Kim Lawden
IPC分类号： A61M1/36 , B01J20/22 , B01J20/32 , C02F1/28 , C07D251/50 , C07D251/70 , C07D403/12 , C07D403/14 , A61K38/00 , A61K31/513 , A61K31/53
CPC分类号： G01N33/579 , B01J20/262 , B01J20/265 , B01J20/3212 , B01J20/3219 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J20/3255 , C02F1/285 , C07D251/50 , C07D251/70 , C07D403/12 , C07D403/14
摘要： An affinity ligand-matrix conjugate comprises the matrix and conjugated thereto by the group Z, a ligand having general formula (I): wherein one X is N and the other X is N, CCL or CCn; A1 and A2 are each independently O, S or N—R1 and R1 is H, C1-6 alkyl, C1-6 hydroxyalkyl, benzyl or β-phenylethyl; B1 and B2 are each independently an optionally substituted hydrocarbon linkage containing from 1 to 10 carbon atoms; D1 is H or a primary amino, secondary amino, tertiary amino, quaternary ammonium, imidazole, guanidine or amidino group; and D2 is a secondary amino, tertiary amino, quaternary ammonium, imadazole, guanidine or amidino group; or B2-D2 is —CHCOOH—(CH2)3-4—NH2; and p is 0 or 1. Such conjugates are useful for the separation, isolation, purification, characterization, identification or quantification of an endotoxin.
摘要翻译：亲和配体 - 基质缀合物包含基质并由基团Z结合，具有通式（I）的配体：其中一个X为N，另一个为N，CCL或CCn; A1和A2各自独立地为O，S或N-R1，R1为H，C1-6烷基，C1-6羟基烷基，苄基或β-苯乙基; B1和B2各自独立地是含有1至10个碳原子的任选取代的烃键; D1是H或伯氨基，仲氨基，叔氨基，季铵，咪唑，胍或脒基; 并且D2是仲氨基，叔氨基，季铵，咪唑，胍或脒基; 或B2-D2为-CHCOOH-（CH2）3-4-NH2; 并且p是0或1.这样的缀合物可用于内毒素的分离，分离，纯化，表征，鉴定或定量。

9. 发明授权

US06573307B1 Process for making fluorinated polymer adsorbent particles 失效
标题翻译：制备氟化聚合物吸附剂颗粒的方法
公开(公告)号：US06573307B1
公开(公告)日：2003-06-03
申请号：US09980901
申请日：2002-04-15
申请人： Leonard H. Smiley , Christopher Lowe , Julie Tucker
发明人： Leonard H. Smiley , Christopher Lowe , Julie Tucker
IPC分类号： C08J926
CPC分类号： B01D15/325 , B01D15/1807 , B01D15/366 , B01D15/3804 , B01D2215/021 , B01J20/26 , B01J20/286 , B01J20/287 , C12N15/1006 , C12N15/101 , G01N2030/042 , Y10S435/803
摘要： A process to make particles by anaerobic reaction of a water-insoluble solution of organic compounds comprising (a) a monomer selected from C2-4 alkylene glycol esters of a C3-6 acrylic acid and a divinyl benzene; (b) a polyfluorinated vinyl monomer; (c) a monomer selected from acrylic acid, methacrylic acid and esters thereof; (d) a free radical initiator; and (e) a water-insoluble, organic solvent-soluble porogenic material, the weight ratio of comonomers (a) plus (b) plus (c) to the porogenic material being from 0.5:1 to 2:1. The adsorbent particles produced by the process are useful in carrying out chromatographic separations, or in the production of medical devices.
摘要翻译：一种通过水不溶性有机化合物溶液的厌氧反应制备颗粒的方法，包括（a）选自C 3-6亚烷基二醇酯和二乙烯基苯的单体; （b）多氟乙烯基单体; （c）选自丙烯酸，甲基丙烯酸及其酯的单体; （d）自由基引发剂; 和（e）水不溶性有机溶剂可溶性致孔材料，共聚单体（a）加（b）加（c）与致孔材料的重量比为0.5:1至2:1。通过该方法生产的吸附剂颗粒可用于进行色谱分离或用于生产医疗器械。

10. 发明授权

US06169090A Heterocyclic compounds and their therapeutic use 失效
标题翻译：杂环化合物及其治疗用途
公开(公告)号：US06169090A
公开(公告)日：2001-01-02
申请号：US09328182
申请日：1999-06-08
申请人： Hazel Joan Dyke , Verity Margaret Sabin , Andrew Sharpe , Alan Findlay Haughan , Christopher Lowe , George Buckley , John Montana
发明人： Hazel Joan Dyke , Verity Margaret Sabin , Andrew Sharpe , Alan Findlay Haughan , Christopher Lowe , George Buckley , John Montana
IPC分类号： C07D491048
CPC分类号： C07D491/04
摘要： The compound, according to formula (i) wherein X and Y are independently CH, N or N-oxide, provided that X and Y do not both represent CH; Z is CO or CS; R1 is alkyl, optionally substituted with one or more halogens; and R2, R3, R4 and R5 are each various organic groups. Such compounds have therapeutic utility, via inhibition of phosphodiesterase IV.
摘要翻译：根据式（ⅰ）的化合物，其中X和Y独立地是CH，N或N-氧化物，条件是X和Y不都表示CH; Z是CO或CS; R1是烷基，任选被一个或多个卤素 R2，R3，R4和R5分别是各种有机基团。这些化合物通过抑制磷酸二酯酶IV具有治疗效用。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式