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1. 发明授权

US5578067A Medical electrode system having a sleeve body and control element therefor for selectively positioning an exposed conductor area 失效
标题翻译：医用电极系统具有套筒体及其控制元件，用于选择性地定位暴露的导体区域
公开(公告)号：US5578067A
公开(公告)日：1996-11-26
申请号：US416221
申请日：1995-04-04
申请人： Christer Ekwall , Kurt Hognelid
发明人： Christer Ekwall , Kurt Hognelid
IPC分类号： A61N1/05 , A61N1/365 , A61N1/375
CPC分类号： A61N1/056
摘要： An electrode apparatus, such as an intravascular or intracardiac pacemaker or defibrillation electrode with an electrode cable has a jacket of insulation enclosing a first elongated, flexible conductor, connected to a first electrode arranged on the electrode cable, and also enclosing at least a second conductor, connected to a conductive surface forming a second electrode arranged on the electrode cable at a distance from the first electrode. In order to achieve an electrode apparatus with which the distance between the electrode on the electrode cable cart be changed in a very simple manner and in which the surface area exposed to tissue of at least one electrode can be enlarged, reduced and even rotated around the electrode cable in certain instances, the electrode apparatus is equipped with at least one sleeve-like body, insulated against the surroundings and slidable on the electrode cable, which at least partially covers the conductive surface and with which the second electrode can be formed whose position in relation to the first electrode and/or whose size can be varied.
摘要翻译：诸如血管内或心脏起搏器或具有电极电缆的除颤电极之类的电极装置具有绝缘套，其包围第一细长柔性导体，连接到布置在电极电缆上的第一电极，并且还包围至少第二导体连接到导电表面，所述导电表面在距离所述第一电极一定距离处形成布置在所述电极电缆上的第二电极。为了实现电极电缆车上的电极之间的距离以非常简单的方式改变的电极装置，并且其中暴露于至少一个电极的组织的表面积可以被放大，减小甚至围绕电极电缆在某些情况下，电极装置配备有至少一个套筒状体，其绝缘抵抗周围环境并且可在电极电缆上滑动，电极电缆至少部分地覆盖导电表面并且可以形成第二电极的位置相对于第一电极和/或其尺寸可以变化。

2. 发明授权

US5571164A Cardiac electrode device having at least a portion thereof which is ribbon shaped 失效
标题翻译：心电极装置具有至少一部分为带状的心电极装置
公开(公告)号：US5571164A
公开(公告)日：1996-11-05
申请号：US533250
申请日：1995-09-25
申请人： Christer Ekwall , Jakub Hirschberg , Kurt Hognelid
发明人： Christer Ekwall , Jakub Hirschberg , Kurt Hognelid
IPC分类号： A61B5/042 , A61N1/05 , A61N1/362
CPC分类号： A61B5/6852 , A61B5/0422 , A61N1/056 , A61B2562/0209 , A61B2562/043
摘要： An electrode device, for intracardiac stimulation and/or defibrillation of heart tissue and/or sensing heart signals in a patient, has a soft, flexible electrode cable with an outer coating of insulation containing at least one elongate conductor connected to an electrode arranged on the electrode cable. In order to attain an electrode device of this kind which is structurally very simple and in which all the electrodes on the electrode cable can be applied to the heart wall in a very simple manner so the entire electrode surface faces the wall and firmly presses against it, the electrode cable is at least partially ribbon-shaped.
摘要翻译：用于心脏刺激和/或心脏组织除颤和/或感测患者心脏信号的电极装置具有软的柔性电极电缆，其具有外部涂层绝缘体，其包含至少一个连接到布置在所述电极上的电极的细长导体电极电缆。为了获得这样一种结构上非常简单的电极装置，其中电极电缆上的所有电极可以以非常简单的方式施加到心脏壁上，使得整个电极表面面向壁并且牢固地压靠在其上电极电缆至少部分是带状的。

3. 发明授权

US5193538A In vivo implantable medical device with battery monitoring circuitry 失效
标题翻译：具有电池监测电路的VIVO可植入医疗器械
公开(公告)号：US5193538A
公开(公告)日：1993-03-16
申请号：US743391
申请日：1992-01-09
申请人： Christer Ekwall
发明人： Christer Ekwall
IPC分类号： A61N1/37 , A61N1/378
CPC分类号： A61N1/378 , A61N1/3708
摘要： It is known that modern implantable electromedical devices for the stimulation of a physiological function, such as pacemakers, are programmable to work in different stimulating modes and comprise sensing and evaluating means for monitoring the capacity of the battery within the device. In order to achieve a constant time duration between the point in time when the battery capacity drops below a threshold value and the end of life of the battery, said threshold value is varied in dependence on the utilized stimulating mode in such a way that a higher threshold value is selected for a stimulating mode with a high energy consumption and vice versa.
摘要翻译： PCT No.PCP / FP90 / 00239 Sec。 371日期1992年1月9日 102（e）日期1992年1月9日PCT提交1990年2月14日PCT公布。出版物WO90 / 09208 日期1990年8月23日。已知用于刺激生理功能的现代植入式电动医疗装置（例如起搏器）可编程为以不同的刺激模式工作，并且包括用于监测电池内部的电池的容量的感测和评估装置设备。为了在电池容量下降到低于阈值的时间点与电池的寿命终止之间实现恒定的持续时间，所述阈值根据利用的刺激模式而变化，使得较高对于具有高能量消耗的刺激模式选择阈值，反之亦然。

4. 发明授权

US06256538B1 Implantable heart stimulator 有权
标题翻译：植入心脏刺激器
公开(公告)号：US06256538B1
公开(公告)日：2001-07-03
申请号：US09341941
申请日：1999-09-22
申请人： Christer Ekwall
发明人： Christer Ekwall
IPC分类号： A61N1365
CPC分类号： A61N1/365 , A61B5/0535 , A61B5/1107 , A61B7/00 , A61N1/36514 , A61N1/36521 , A61N1/36564
摘要： An implantable heart stimulator has a control unit which controls the delivery of stimulation pulses to a subject, and an ischemia detector. The control unit is connected to the ischemia detector and reduces the stimulation rate in response to a detection of ischemia.
摘要翻译：可植入心脏刺激器具有控制单元，其控制对受试者的刺激脉冲的输送和缺血检测器。控制单元连接到缺血检测器，并响应于局部缺血的检测而降低刺激速率。

5. 发明授权

US06233486B1 Ischemia detector and heart stimulator provided with such an ischemia detector 失效
标题翻译：缺血检测器和心脏刺激器配备有这样的缺血检测器
公开(公告)号：US06233486B1
公开(公告)日：2001-05-15
申请号：US09341944
申请日：1999-07-20
申请人： Christer Ekwall , Christina Nyhlén
发明人： Christer Ekwall , Christina Nyhlén
IPC分类号： A61B500
CPC分类号： A61N1/36564 , A61B5/0215 , A61M2025/0002 , A61M2210/125
摘要： An ischemia detector has a sensor unit which determines the systolic pressure of a subject, a unit wherein a relation is established between the systolic pressure and the subject's heart rate, as the heart rate is varied over a range, and an analyzer which determines the occurrence of ischemia from this relation.
摘要翻译：缺血检测器具有确定受试者的收缩压的传感器单元，其中在心率在一定范围内变化时，在收缩压与受试者的心率之间建立关系的单元，以及确定发生的分析仪的这种关系的缺血。

6. 发明授权

US5016634A Implantable medical device with means for telemetric transmission of data 失效
标题翻译：具有遥测数据传输方式的植入式医疗设备
公开(公告)号：US5016634A
公开(公告)日：1991-05-21
申请号：US505509
申请日：1990-04-06
申请人： Josef Vock , Jan Ljungstroem , Christer Ekwall
发明人： Josef Vock , Jan Ljungstroem , Christer Ekwall
IPC分类号： A61N1/365 , A61N1/37 , A61N1/372
CPC分类号： A61N1/37211
摘要： A medical device adapted to be implanted in a patient includes components for detecting physiological events and/or for stimulating physiological events, and includes control logic connected to the detecting and or stimulating components, and further components for the telemetric transmission of data relating to the logical status of the control logic to and from an external receiver. The components for telemetrically transmitting data are connected to the control logic, and continuously transmit data identifying the current logical status of the control logic to the external receiver.
摘要翻译：适于植入患者的医疗装置包括用于检测生理事件和/或用于刺激生理事件的组件，并且包括连接到检测和/或刺激部件的控制逻辑，以及与逻辑相关的数据的遥测传输的其他部件来自外部接收器的控制逻辑的状态。用于遥测数据传输的组件连接到控制逻辑，并将识别控制逻辑的当前逻辑状态的数据连续发送到外部接收器。

7. 发明授权

US4827934A Sensing margin detectors for implantable electromedical devices 失效
标题翻译：用于植入式电子医疗设备的感应余量检测器
公开(公告)号：US4827934A
公开(公告)日：1989-05-09
申请号：US114327
申请日：1987-10-27
申请人： Christer Ekwall
发明人： Christer Ekwall
IPC分类号： A61N1/365 , A61N1/37
CPC分类号： A61N1/3706 , A61N1/36514
摘要： Circuitry for quantitatively determining the level of processed heart signals relative to actual sensing sensitivity level (threshold) in an implantable pacemaker. The measurement is useful for adjusting the settable threshold, polarity, filtering or amplification parameter settings for safe operation and noise rejection of the pacemaker.
摘要翻译：用于定量确定可植入心脏起搏器中相对于实际感测灵敏度水平（阈值）的经处理的心脏信号的电平的电路。该测量对于调整起搏器的安全操作和噪声抑制的可设定阈值，极性，滤波或放大参数设置非常有用。

8. 发明授权

US06591143B1 Bending sensor for an implantable lead and a heart stimulator with a lead having such a sensor 失效
标题翻译：用于可植入引线的弯曲传感器和具有这种传感器的引线的心脏刺激器
公开(公告)号：US06591143B1
公开(公告)日：2003-07-08
申请号：US09555085
申请日：2000-05-24
申请人： Christer Ekwall
发明人： Christer Ekwall
IPC分类号： A61N100
CPC分类号： A61N1/056 , A61B5/042 , A61B5/1107 , A61B5/686 , A61B2562/0261 , A61B2562/222 , A61N1/36521
摘要： A sensor arrangement, and a heart stimulator employing such a sensor arrangement, identify bending of an electrode lead. A lead which is implantable in a patient is subjected to bending due to movement of the surrounding tissue, and the lead has a deformation sensor therein which emits an electrical signal dependent on the magnitude and orientation of the bending. The deformation sensor can be formed by two parallel channels extending from the tip of the lead within an insulating sleeve of the lead which encloses a conductor element. The channels are filled with an electrically conductive fluid and are connected at their opposite ends to a resistance measuring unit. Bending of the lead causes the resistance of the fluid to change, which is measured by the resistance measuring unit. The channels can be disposed asymmetrically relative to a longitudinal axis of the lead, so that orientation of the bending can also be identified by comparing signals from the respective channels to each other.
摘要翻译：传感器装置和使用这种传感器装置的心脏刺激器识别电极引线的弯曲。可植入患者的引线由于周围组织的移动而受到弯曲，并且引线在其中具有取决于弯曲的大小和取向的电信号的变形传感器。变形传感器可以由两个平行的通道形成，该两个平行的通道在引线的绝缘套管内从引线的顶端延伸，该绝缘套管包围导体元件。通道填充有导电流体，并在其相对端连接到电阻测量单元。铅的弯曲会导致流体的电阻变化，这是由电阻测量单元测量的。通道可以相对于引线的纵向轴线非对称地布置，从而也可以通过将来自各个通道的信号彼此进行比较来识别弯曲的取向。

9. 发明授权

US6016443A Implantable ischemia detector and implantable stimulator employing same 失效
标题翻译：植入式缺血检测器和采用其的可植入式刺激器
公开(公告)号：US6016443A
公开(公告)日：2000-01-18
申请号：US48521
申请日：1998-03-26
申请人： Christer Ekwall , Kjell Noren
发明人： Christer Ekwall , Kjell Noren
IPC分类号： A61N1/365 , A61B5/04
CPC分类号： A61N1/36514 , A61N1/36585
摘要： An ischemia detector includes repolarization sensor which senses repolarization of the heart of a patient and delivers corresponding repolarization signals to a detecting unit and a workload sensor which senses the workload of the patient and delivers corresponding workload signals to the detecting unit. The detecting unit identifies a state of ischemia as existing upon the occurrence of a predetermined relation between sensed repolarization and sensed workload.
摘要翻译：缺血检测器包括复极度传感器，其感测患者心脏的复极化，并将相应的复极信号传送到检测单元和工作负载传感器，其感测患者的工作量并将相应的工作负载信号传送到检测单元。检测单元在检测到的复极化和检测到的工作负荷之间发生预定关系时，识别存在的局部缺血状态。

10. 发明授权

US5601614A Method and device for determining whether electrical signals in a heart are caused by an atrial depolarization 失效
标题翻译：用于确定心脏中的电信号是否由心房去极化引起的方法和装置
公开(公告)号：US5601614A
公开(公告)日：1997-02-11
申请号：US227325
申请日：1994-04-14
申请人： Christer Ekwall
发明人： Christer Ekwall
IPC分类号： A61B5/0428 , A61N1/365 , A61N1/37 , A61N1/362
CPC分类号： A61N1/3702 , A61N1/365
摘要： In a method and apparatus for determining whether electrical signals in a heart are caused by atrial depolarizations or ventricular depolarizations, heart signals are sensed in the upper part of the ventricular heart tissue, preferably the upper part of the ventricular septum. The detection of heart signals from both the atrium and ventricle and the identification of depolarization is facilitated if the course of the signals is monitored, with monophasic heart signals being caused by an atrial depolarization and biphasic signals being caused by a ventricular depolarization.
摘要翻译：在用于确定心脏中的电信号是否由心房去极化或心室去极化引起的方法和装置中，在心室心脏组织的上部，优选心室隔膜的上部感测到心脏信号。如果监测信号的过程，则单向心脏信号由心房去极化引起，双相信号由心室去极化引起，来自心房和心室的心脏信号的检测和去极化的识别是有利的。

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